Disney+ has ordered a new series for the Marvel character, picking up where WandaVision left off.

The post Vision Is Getting His Own Show, From Star Trek’s Terry Matalas first appeared on SciFi Stream.

Catalase is an antioxidant enzyme that breaks down hydrogen peroxide (H2O2) into molecular oxygen and water. In all monofunctional catalases the pathway that H2O2 takes to the catalytic centre is via the `main channel'. However, the structure of this channel differs in large-subunit and small-subunit catalases. In large-subunit catalases the channel is 15 Å longer and consists of two distinct parts, including a hydrophobic lower region near the heme and a hydrophilic upper region where multiple H2O2 routes are possible. Conserved glutamic acid and threonine residues are located near the intersection of these two regions. Mutations of these two residues in the Scytalidium thermophilum catalase had no significant effect on catalase activity. However, the secondary phenol oxidase activity was markedly altered, with kcat and kcat/Km values that were significantly increased in the five variants E484A, E484I, T188D, T188I and T188F. These variants also showed a lower affinity for inhibitors of oxidase activity than the wild-type enzyme and a higher affinity for phenolic substrates. Oxidation of heme b to heme d did not occur in most of the studied variants. Structural changes in solvent-chain integrity and channel architecture were also observed. In summary, modification of the main-channel gate glutamic acid and threonine residues has a greater influence on the secondary activity of the catalase enzyme, and the oxidation of heme b to heme d is predominantly inhibited by their conversion to aliphatic and aromatic residues.

Staff of the National Centre of the Kyrgyz Republic for the Prevention of Torture, with support of the OSCE Centre in Bishkek will conduct monitoring visits to the detention facilities in Isyk-Kul, Naryn and Talas provinces between 10 and 17 August. These visits aim at monitoring detention conditions and human rights situation in the closed facilities.

The monitoring findings will be included in the 2016 Annual Report of the National Centre for the Prevention of Torture.

Related Stories

• OSCE Centre supports the 3rd training for prosecutors on effective investigation of cases of torture in Kyrgyzstan
• To mark World Day against Trafficking in Persons OSCE Centre in Bishkek supports public awareness raising campaign
• OSCE Centre in Bishkek supports summer school on topical issues of police reform

A statement issued by the rocker's family reveals that the 63-year-old passed away on May 2 night surrounded by his family and closest friends at his home in Rochester.

Fischbach, Margaret A