In the final broadcast of TOTN, NPR senior Washington editor Ron Elving, senior business editor Marilyn Geewax and science correspondent Richard Harris discuss the big stories they're covering. Callers talk about the issues that have their communities and social circles abuzz.

In today’s rapidly evolving digital landscape, managing IP infrastructure has become increasingly complex and critical for organizations of all sizes. As networks

The post Don’t Ignore What You Can Easily Control: Your IP Infrastructure appeared first on Gigaom.

Chinese business people may be able to find creative ways to avoid U.S. tariffs, but for Beijing, its concerns for the incoming Trump presidency go beyond trade.

Jyotsana Jagannathan and Brindha Manikavasagan brought alive the myriad facets of Meenakshi through their refreshing approach

Marvel Animation’s ‘What If...?’ Season 3 trailer has revealed new characters and genres. The final season will premiere on Disney Plus on December 22, 2024

Join Sean Gallagher, Dell's Ivan Nekrasov, and me today, January 21, at 3:15pm Eastern!

As humans leave space junk behind, there may come a time when human bodies would need to decompose in space. Learn how this happens and why it's a slow process.

Research suggests that cats can learn words, sometimes faster than a human baby.

There is not a ton of evidence of what education looked like in ancient society, but we do know it existed - although not for everyone.

On day one of Donald Trump's presidency, Robert F. Kennedy Jr. says he'll be advising Trump to take fluoride out of public water. The former presidential hopeful — and prominent proponent of debunked public health claims — has described fluoride as "industrial waste."

Generational curses impact family patterns and behaviors. Learn how to identify, break, and heal from ancestral trauma to free yourself and future generations.

Earthquakes are among the most powerful natural forces on Earth, often causing widespread devastation, triggering tsunamis and altering the landscape of a region. But how strong was the strongest earthquake of all time?

Angel number 33 symbolizes spiritual growth, compassion, and creativity. Discover its powerful meaning in love, career, and life purpose as a Master Number.

The United States is home to some truly spectacular lakes. Whether considering the massive Great Lakes themselves or deep alpine gems like Lake Tahoe, with its crystal-clear waters, America is well-stocked with many sizable bodies of water.

As Toronto readies for Taylor Swift's arrival this week, some crowd management and planning experts say additional safety precautions should be taken when tens of thousands of fans fill the city's downtown core on show nights.

The federal government ordered an end to TikTok's Canadian operations on Wednesday, citing national security concerns. But its decision to keep the app itself available has privacy experts puzzled.

Robert Musselle, customer engineering manager EMEA at Protolabs shares what you need to consider with 3D printing and plastics prototyping.

A strange supernova remnant first appeared as a “guest star” seen in 1181 by sky watchers in China and Japan

The new president-elect can go beyond just pulling out of the Paris Agreement. But it may be more difficult to roll back clean energy policies

This week, I’m rerunning some popular posts while we put the finishing touches on DCI’s new 2024-25 Economic Report on Pharmaceutical Wholesalers and Specialty Distributors.

Last week, the Federal Trade Commission (FTC) released the redacted version of administrative complaint against the three largest pharmacy benefit managers (PBMs). The FTC rightly calls out how the gross-to-net bubble can raise patients’ out-of-pocket costs, while also acknowledging how rebates can reduce a plan's (but not the patient’s) costs. Apparently, the FTC believes that PBMs’ customers are pretty dumb, because PBMs are able to prevent plans from “appreciating” such healthcare financing dynamics.

Section V.E. of the complaint (starting on page 23) focuses on the PBMs’ alleged unlawful conduct related to preferring high-list/high-rebate insulin products over versions with lower list prices. I thought it would therefore be fun to take the Wayback Machine to November 2021, when I wrote about this specific topic.

Below, you can review my commentary about the warped incentives behind Viatris’ dual-pricing strategy for its interchangeable biosimilar of Lantus. Much of the FTC’s description of the drug channel aligns with my commentary. But before you fist pump too hard for Ms. Khan’s FTC, you should pause to reflect on the agency’s legal theories in light of plans’ revealed preferences.

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The Food & Drug Administration (FDA) recently approved the first interchangeable biosimilar insulin product: the insulin glargine-yfgn injection from Viatris. Read the FDA’s press release.

Alas, I’m sad to report that the warped incentives baked into the U.S. drug channel will limit the impact of this impressive breakthrough.

Viatris is being forced to launch both a high-priced and a low-priced version of the biosimilar. However, only the high-list/high-rebate, branded version will be available on Express Scripts’ largest commercial formulary. Express Scripts will block both the branded reference product and the lower-priced, unbranded—but also interchangeable—version. Meanwhile, Prime Therapeutics will place both versions on its formularies, leaving the choice up to its plan sponsor clients.

Consequently, many commercial payers will adopt the more expensive product instead of the identical—but cheaper—version. As usual, patients will be the ultimate victims of our current drug pricing system.

Below, I explain the weird economics behind this decision, highlight the negative impact on patients, and speculate on what this all could mean for biosimilars’ future. Until plan sponsors break their addiction to rebates, today’s U.S. drug channel problems will remain.
Read more »

Today’s guest post comes from Greg Skalicky, President, EVERSANA and Faruk Abdullah, President, Professional Services & Chief Business Officer, EVERSANA

Greg and Faruk walk through the marketplace pressures driving Direct-to-Patient commercialization models. They argue that a technology-enabled infrastructure,  combined with clinical and reimbursement support specialists, can improve  patients' access to new therapies, shorten the time to therapy, and enable better overall clinical outcomes.

Click here to learn more about EVERSANA’s Direct-to-Patient care model.

Read on for Greg and Faruk’s insights.
Read more »

The U.S. Food and Drug Administration posted a video:

What happens after a drug is approved? And how and why do drug recalls happen? Learn more in this short video from FDA’s Center for Drug Evaluation and Research (CDER).

The U.S. Food and Drug Administration posted a video:

What happens after a drug is approved? And how and why do drug recalls happen? Learn more in this short video from FDA’s Center for Drug Evaluation and Research (CDER).

The U.S. Food and Drug Administration posted a video:

The FDA oversees prescription, generic, biosimilars, and over-the-counter drugs. But what is the FDA’s role when it comes to drug regulation? Learn more in this short video from FDA’s Center for Drug Evaluation and Research (CDER).

The U.S. Food and Drug Administration posted a video:

The FDA oversees prescription, generic, biosimilars, and over-the-counter drugs. But what is the FDA’s role when it comes to drug regulation? Learn more in this short video from FDA’s Center for Drug Evaluation and Research (CDER).

We still don’t know what COVID-19 is doing to the heart or how we should be investigating it and treating it. Last month JAMA Cardiology published a German cohort study of 100 patients recently recovered from COVID-19… A number of striking problems with the study were noted on Twitter…...

Click here to continue reading...

By Ankit Mahadevia, chairman of Spero Therapeutics, as part of the From The Trenches feature of LifeSciVC A common theme in startup literature is that by cutting a range of unnecessary tasks, a step-change in results will follow.  I’ve found

The post Keeping It Simple: What Really Matters For Emerging Enterprises   appeared first on LifeSciVC.

President-elect Donald Trump tried unsuccessfully to get rid of the Affordable Care Act during his first term. What action will he take this time around?

As a leader who has committed much of his career to improving healthcare — an industry that holds millions of people’s lives in its hands — I took from this terrifying incident a new guiding principle. Healthcare needs to pursue a zero-failure rate.

The post What My Daughter’s Harrowing Alaska Airlines Flight Taught Me About Healthcare appeared first on MedCity News.

Many companies are entering the digital youth mental health space, but it’s important to know which ones are effective, according to a panel of investors at the Behavioral Health Tech conference.

The post Measuring Impact in Digital Youth Mental Health: What Investors Look For appeared first on MedCity News.

Experts agree that the incoming Trump administration will likely shake things up in the prescription drug world — most notably when it comes to research and development, drug pricing and PBM reform.

The post What Might the Future of Prescription Drugs Look Like Under Trump? appeared first on MedCity News.

Hospitals across the U.S. have significantly restricted the use of pain medications containing narcotics. This shift comes amid […]

The post Pain Management in Crisis: Why Hospitals Are Limiting Pain Medications and What This Means for Patients appeared first on World of DTC Marketing.

The Centers for Medicare and Medicaid Services (CMS) recently announced a 2.9% cut to Medicare physician payments for […]

The post CMS Cuts Medicare Physician Payments: What It Means appeared first on World of DTC Marketing.

Oct 27, 2022

Kennedy’s statecraft in the missile crisis provides a rich source of clues that can help illuminate the challenge the United States now faces, and the choices President Joe Biden is making.

Aug 31, 2015

There is growing evidence that the Chinese economic miracle is a consequence of the rural entrepreneurship which started in the 1980s. This contradicts classical interpretations that focus on state-led enterprises and receptiveness to foreign direct investment....The lesson from China's experience is that development must be viewed as an expression of human potentialities, not as a product of external interventions.

Apr 5, 2024

6 months on: What is the impact of the war in Gaza?
Brookings experts reflect on the conflict

Dec 21, 2023

Artificial intelligence is poised to remove human limitations inherent in many systems, including information and logistical bottlenecks in decision-making.

 

Apr 2, 2024

Stephen Walt argues that because no one knows what Putin might do, NATO's European members should increase their defense capabilities and correct any obvious vulnerabilities. At the same time, however, the United States and its NATO allies should acknowledge Russia's legitimate security concerns and consider what they can do to allay them.

Jun 5, 2024

When asked whether the U.S. government works, most Americans say no. According to recent polling by Ipsos, more than two-thirds of adults in the United States think the country is going in the wrong direction. Gallup reports that only 26 percent have confidence in major U.S. institutions, such as the presidency, the Supreme Court, and Congress. Nearly half of Americans aged 18 to 25 say that they believe either that democracy or dictatorship “makes no difference” or that “dictatorship could be good in certain circumstances.” As a recent Economist cover story put it: “After victory in the Cold War, the American model seemed unassailable. A generation on, Americans themselves are losing confidence in it.”

May 30, 2024

The intersessional conference stands as one of the most important regular milestones in international climate negotiations, but its relatively unknown status compared to the COPs has made it difficult to understand its place in international climate policymaking.

Jun 3, 2024

As the climate crisis intensifies, demand is surging for minerals needed to manufacture clean energy technologies. In the race to secure supplies of critical minerals, Africa and the Arctic have taken center stage as companies and governments around the world eye their vast mineral deposits. These seemingly disparate regions now face the same question: how to capitalize on their mineral wealth while maximizing the socioeconomic benefits and minimizing the environmental harms of mining.

May 6, 2024

Stephen Walt advises protesters that people who haven't made up their minds yet are usually attracted by facts, logic, reason, and evidence. In his experience, they are turned off by anger, rudeness, intolerance, and especially by anyone who interferes with their own desire to learn more.

Jun 20, 2024

Stephen Walt argues that Americans who are deeply worried about China's rise should reflect on what Beijing has done well and what Washington has done poorly.

John Peden - #NMClientStory

Rob Riggle Stars alongside Brice Williams in the newest Easter Seals Dixon Center PSA, directed by Jim Fabio with support from Judd Apatow

Smartphones hold increasing amounts of sensitive personal data, so every device is now a mixed-use device. As a result, businesses must protect employee privacy as fiercely as corporate security.

Alien Invasion Might Happen

CES 2016: WHAT�S NEXT IN HIGH TECH!

Neutrogena� Launches See What�s Possible

Everyday Health Inc. Introduces the What to Expect Pregnancy Clock Apple Watch� app.