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BRITs 2020: Lewis Capaldi and Stormzy lead male-dominated award winners

Lewis Capaldi, Stormzy and Billie Eilish led the winners on Tuesday evening in a largely male dominated BRIT Awards shortlist.




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Formula One mourn the death of Stirling Moss as Valtteri Bottas and George Russell lead the tributes

Moss, who was often described as the greatest driver never to win the World Championship, passed away in the early hours of Easter Sunday at his London home following a long battle with illness.




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Covidiot leads police on 151mph chase up the M1 as chief warns offences have doubled under lockdown

Drivers were caught driving at 'extreme speeds' on quiet roads over the Easter weekend, including a man who was clocked at 151mph on the M1 near London as he led police on a high-speed chase.




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Why state leaders need to end lockdown now

Leaders in Victoria and New South Wales refused to make any changes and suggested most rules will be in place until June - even though we've had only four coronavirus deaths in the past week.




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Will it be another Super Saturday? Jess Ennis-Hill heads possible gold rush as she leads heptathlon while London 2012 stars Mo Farah and Greg Rutherford prepare for their shots at glory

Golden girl Ennis-Hill was not at her best in the throwing event in Rio but was able to jump up one place from third after registering a 13.86m throw.




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Jessica Ennis-Hill loses heptathlon lead at Rio 2016

Jessica Ennis-Hill remains on course to defend her Olympic heptathlon title with just two events remaining after producing a solid performance in the long jump.




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Mark Cavendish and Greg Rutherford lead British athletes' Rio Olympics 2016

Britain's bronze medal long jumper Greg Rutherford had an emotional reunion with his partner Susie Verrill and son Milo, while silver medallist Mark Cavendish also returned from Rio.




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Mo Farah and Jessica Ennis-Hill lead list of sporting stars to be acknowledged in New Year Honours

Two of Great Britain's greatest track and field athletes, Mo Farah and Jessica Ennis-Hill, lead the list of sporting stars to be acknowledged in the New Year Honours.




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Stormzy leads celebrities tweeting support for bullied boy

Christopher Hope-Smith, from Leeds, took to Twitter to ask famous people could send birthday greetings to Ollie, who turns nine on July 9th. Several celebrities have responded to his request.




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'That's not fair - give me a break': Matt Hancock pleads to PM in clash over UK's COVID-19 response

Matt Hancock is living on 'borrowed time' as Health Secretary following clashes with the three most powerful members of the Government over the Covid crisis, The Mail on Sunday has been told.




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Theresa May leads mourners at Sir Jeremy Heywood's memorial service

Former Cabinet Secretary Sir Jeremy Heywood lost his battle with cancer last November and was remembered at a memorial service at Westminster Abbey this afternoon.




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Cong leaders making absurd remarks, weakening fight against COVID-19: BJP

Dubbing Congress' criticism of the central government's handling of COVID-19 crisis as "absurd", the BJP on Saturday said the opposition party is weakening the country's fight against COVID-19 instead of extending cooperation. BJP's national media incharge Anil Baluni said Congress leaders, on a regular basis, are making "absurd statements on the behest of their party president Sonia Gandhi and Rahul Gandhi, to remain relevant in news". Baluni said the BJP-led government at the Centre welcomes Opposition's constructive suggestions in the battle against COVID-19, but "the opposition party should not do politics" over the pandemic. "Rather than becoming a part of the battle against COVID-19, the Congress is unfortunately resorting to politics and its leaders are trying to weaken the fight by making absurd statements, Baluni said. Underscoring that India has done relatively well than other countries and has been praised for effectively handling the coronavirus, Baluni said the Congress ..




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Senior BJD leader & WODC chairman Subhas Chauhan dies

Senior Biju Janata Dal (BJD) leader and Chairman of the Western Odisha Development Council (WODC), Subash Chauhan died at a private hospital here on Sunday following a prolonged illness. He was 54. Chauhan, who was undergoing treatment for liver ailment was a bachelor and breathed his last in the morning, family sources said. Closely associated with the RSS and VHP for many years, the former national Convenor of the Bajrang Dal had quit the BJP and joined the Biju Janata Dal in the run-up to the 2019 general elections. Chauhan was subsequently appointed the chairman of WODC in September last year. A host of dignitaries including Odisha Chief Minister Naveen Patnaik and Union Ministers Dharmendra Pradhan and Pratap Sarangi condoled the demise of Chauhan describing it as a big loss for the state. Expressing deep grief, Patnaik said the contributions made by Chauhan for the welfare of the people will always be remembered by all in the state. Praying for peace for the ...




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Want to be a leader? Here's the place to be




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Rebel leader was spreading Covid-19 awareness when killed: Maoists




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State board principals’ association leading a ‘tech revolution’




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Punjab: Congress leaders' wives speak against booze home delivery

Even though reopening of liquor vends is a priority for the state Congress government, wives of two prominent leaders of the ruling party - cabinet minister Bharat Bhushan Ashu and MLA Amarinder Singh Raja Warring - have asked chief minister Amarinder Singh to reconsider home delivery of liquor during lockdown.




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Maa Jaisa Koi Nahi: Virat Kohli and Virender Sehwag Lead Mother's Day Wishes

Kohli, who has been actively doing his bit to help during the coronavirus lockdown along with wife Anushka Sharma, posted a couple of pictures with his mother on social media.




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Senior Biju Janata Dal Leader Subhas Chauhan Dies At 54

Senior Biju Janata Dal (BJD) leader and Chairman of the Western Odisha Development Council (WODC), Subash Chauhan died at a private hospital in Bhubaneswar on Sunday following a prolonged illness. He...




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When KGF Star Yash's Special Song With Shriya Saran Made The Lead Actor Of The Film Insecure

Rocking Star Yash is one of the best dancers in the Kannada film industry. Way back in 2013, the KGF actor had done a special song with Shriya Saran in Roopa Iyer's film, Chandra, which also starred Prem. But the special




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U.S. to allow states to distribute Gilead's remdesivir to fight COVID-19

The U.S. Department of Health and Human Services (HHS) said on Saturday it would allow state health departments to distribute Gilead Sciences Inc's remdesivir drug to fight COVID-19, and the United States would receive about 40% of the drug maker's global donation.




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COVID-19 & Remdesivir: Coronavirus Patients Recover With Gilead’s Drug

An experimental antiviral drug developed by a research-based biopharmaceutical company, Gilead Sciences showed positive results on its application, where more than half of a group of severely ill coronavirus patients improved. UPDATE: On 29 April, Gilead Sciences Inc. announced that in Phase




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New research can lead to interventions for treating cocaine addiction




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Surat police detains Congress leaders for flagging off train for migrant workers




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Teenage obesity, BP may lead to prematurely aged arteries




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Study suggests sleep disturbances among infants may lead to altered brain development




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TOI widens gap, leads HT by 2.9L in Delhi-NCR readership

The Times of India remains the dominant market leader among English dailies with its total readership of over 1.73 crore, almost equal to the combined readership of the three biggest dailies outside the Times Group – The Hindu, Hindustan Times and The Indian Express. This has emerged from the just released Indian Readership Survey for the fourth quarter (Q4) of 2019.




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6 times when BJP leaders insulted Mahatma Gandhi

Former Union minister and controversial Bharatiya Janata Party MP Anantkumar Hegde has once again stoked a row by calling the freedom struggle led by Mahatma Gandhi a "drama".However, this is not the first time a leader from the ruling party has insulted the Father of the Nation.Here are other instances when BJP leaders took a swipe at Mohandas Karamchand Gandhi.





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TMC leaders hit out at Shah, say West Bengal has seven-stage programme to bring back people




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Meet Bengaluru’s Covid warrior mothers, who are leading the fight against the pandemic

Meet Bengaluru’s Covid warrior mothers, who are leading the fight against the pandemic




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The Warrior Moms: Meet the mothers leading the battle against COVID19

The Warrior Moms: Meet the mothers leading the battle against COVID19




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Meet Bengaluru’s Covid warrior mothers, who are leading the fight against the pandemic

Meet Bengaluru’s Covid warrior mothers, who are leading the fight against the pandemic




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TOI leads HT by 2.9L in Delhi-NCR readership

TOI leads HT by 2.9L in Delhi-NCR readership




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Punjab gangster Budha's interrogation leads to 23 arrests




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Akali Dal leader arrested in last month's drug haul




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SAD leader Majithia slams Punjab DGP for his Kartarpur remark




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Coronavirus will lead to economic slowdown: Punjab CM




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Not interested in leaving Punjab, Rahul Gandhi should steer Congress as its leader: Amarinder




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Punjab enforces statewide lockdown till March 31 (Third Lead)




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Concealing travel history in Punjab can lead to impounding of passport




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Will follow curfew till May 3: Punjab CM to all-party leaders




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Blame on Punjab drivers for corona infections misleading: Minister





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Symmetry-mode analysis for intuitive observation of structure–property relationships in the lead-free antiferroelectric (1−x)AgNbO3–xLiTaO3

Functional materials are of critical importance to electronic and smart devices. A deep understanding of the structure–property relationship is essential for designing new materials. In this work, instead of utilizing conventional atomic coordinates, a symmetry-mode approach is successfully used to conduct structure refinement of the neutron powder diffraction data of (1−x)AgNbO3–xLiTaO3 (0 ≤ x ≤ 0.09) ceramics. This provides rich structural information that not only clarifies the controversial symmetry assigned to pure AgNbO3 but also explains well the detailed structural evolution of (1−x)AgNbO3–xLiTaO3 (0 ≤ x ≤ 0.09) ceramics, and builds a comprehensive and straightforward relationship between structural distortion and electrical properties. It is concluded that there are four relatively large-amplitude major modes that dominate the distorted Pmc21 structure of pure AgNbO3, namely a Λ3 antiferroelectric mode, a T4+ a−a−c0 octahedral tilting mode, an H2 a0a0c+/a0a0c− octahedral tilting mode and a Γ4− ferroelectric mode. The H2 and Λ3 modes become progressively inactive with increasing x and their destabilization is the driving force behind the composition-driven phase transition between the Pmc21 and R3c phases. This structural variation is consistent with the trend observed in the measured temperature-dependent dielectric properties and polarization–electric field (P-E) hysteresis loops. The mode crystallography applied in this study provides a strategy for optimizing related properties by tuning the amplitudes of the corresponding modes in these novel AgNbO3-based (anti)ferroelectric materials.




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Smithsonian to lead study on degradation of nearshore coastal habitats of the Chesapeake

Invasive species, contaminants, excessive nutrient's and sediment are just some of the many factors threatening sensitive wetlands and seagrass beds.

The post Smithsonian to lead study on degradation of nearshore coastal habitats of the Chesapeake appeared first on Smithsonian Insider.




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Evidence of asteroid mining in our galaxy may lead to the discovery of extraterrestrial civilizations

If intelligent and more advanced civilizations exist on other planets then its a good bet that some of these civilizations turned to asteroid mining long ago. If so, the hallmarks of their mining activities, such as unusual dirty halos of cast-off dust and debris around large asteroids, might be detectable from earth.

The post Evidence of asteroid mining in our galaxy may lead to the discovery of extraterrestrial civilizations appeared first on Smithsonian Insider.





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Jamestown skeletons identified as colony leaders

Within the 1608 church where Pocahontas and John Rolfe married, the skeletal remains of four early settlers were uncovered during a 2013 archaeological dig at […]

The post Jamestown skeletons identified as colony leaders appeared first on Smithsonian Insider.




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Serine 319 phosphorylation is necessary and sufficient to induce a Cx37 conformation that leads to arrested cell cycling [RESEARCH ARTICLE]

Samantha-Su Z. Taylor, Nicole L. Jacobsen, Tasha K. Pontifex, Paul Langlais, and Janis M. Burt

Connexin 37 (Cx37) expression profoundly suppresses proliferation of rat insulinoma (Rin) cells in a manner dependent on gap junction channel (GJCh) functionality and the presence and phosphorylation status of its carboxyl-terminus (CT). In Rin cells growth arrested by induced Cx37 expression, serine 319 (S319) is frequently phosphorylated. Preventing phosphorylation at this site (alanine substitution; S319A) relieved Cx37 of its growth suppressive effect whereas mimicking phosphorylation at this site (aspartate substitution; S319D) enhanced Cx37's growth suppressive properties. Like Cx37-WT, -S319D GJChs and hemichannels (HChs) preferred the closed state, rarely opening fully, and gated slowly. In contrast, Cx37-S319A channels preferred open states, opened fully, and gated rapidly. These data indicate that phosphorylation-dependent conformational differences in Cx37 protein and channel function underlie Cx37-induced growth arrest vs. growth permissive phenotypes. That the closed state of -WT and Cx37-S319D GJChs and HChs favors growth arrest suggests that rather than specific permeants mediating cell cycle arrest, the closed conformation instead supports interaction of Cx37 with growth regulatory proteins that result in growth arrest.