On 28 April 2020, the Russian President issued Decree No. 294 On Prolonging Measures To Ensure Sanitary and Epidemiological Wellbeing of the Population in the Russian Federation due to the Spread of the Novel Coronavirus (COVID-19). The following da...

Auto production in Mexico and Brazil, Latin America's top producers, plunged by an unprecedented 99% in April as a result of the coronavirus crisis, with the two countries building a total of just 5,569 vehicles.

Speed brief: On 11 July 2019, the UK Government published legislation confirming its intention to introduce a digital services tax (DST). The key features of this DST are as follows: • 2% tax on revenues (not profit) generated from UK users &bu...

President Cyril Ramaphosa has received a request from the Information Regulator Chairperson to declare that the remaining provisions of the Protection of Personal Information Act (POPIA) commence on 1 April 2020. If the President acts on the Informa...

As web-based child exploitation explodes, cops have to carry on doing their job while trying to stay safe from COVID-19 infection. ......

Turkish Treasury's cash balance this April posted a deficit of 46.2 billion Turkish liras ($6.6 billion), the Treasury and Finance Ministry said on May 8. 

Background The Parental Bereavement (Leave and Pay) Act 2018 received Royal Assent as long ago as 13 September 2018. The intention was the Act would come into force in 2020, with further clarification on the provisions to be contained in regulations...

The U.S. president became his own worst enemy over the course of 30 days.

[Namibian] POLICE arrested 143 suspects for drug-related crimes in April, the latest police report on drug busts and arrests says.

The Labor Department's monthly employment report also showed the unemployment rate surging to 14.7% last month, shattering the post-World War II record of 10.8% touched in November 1982.

China’s exports returned to growth in April, beating forecasts and suggesting that an expected demand shock from coronavirus containment efforts around the world will come further down the line.April exports rose by 3.5 per cent from a year earlier, reversing the 6.6 per cent fall in March and much better than the combined minus 17.2 per cent collapse in January and February. April’s return was much better than the expectations of a Bloomberg poll of analysts, which had predicted an 11 per cent…

Car sales in China likely rose in April from a year earlier, its top industry body said on Thursday, ending almost two years of declines and signalling that the world’s biggest market is recovering from the coronavirus shock.April’s sales of 2 million units likely pushed sales up 0.9 per cent from a year earlier, and 39.8 per cent from March, the China Association of Automobile Manufacturers (CAAM) said in a post on its official WeChat account.It added its forecast was based on sales data it…

A surprise jump in Chinese exports in April will be short-lived, analysts said, with the world’s second largest economy unable to stay sheltered from the demand shock to come from the global economic downturn.A 3.5 per cent rise in shipments last month caught economists by surprise and left them scrambling for explanations as the consensus forecast was for an 11 per cent contraction.The rise was, in part, due to factories coming back online in China in March and April to fulfil orders that had…

With shops and factories closed nationwide due to the coronavirus pandemic, nearly all of the jobs created in the US economy in the last decade were wiped out in a single month.An unprecedented 20.5 million jobs were destroyed in April in the world’s largest economy, driving the unemployment rate to 14.7 per cent compared to 4.4 per cent in March, the Labour Department said in its monthly report, the first to capture the impact of a full month of the lockdowns.The US is home to the world’s…

The coronavirus lockdown wiped out 20.5 million US jobs in April, destroying nearly all the positions created in the previous decade in the world's largest economy, the country's labour department reported on Friday.

The unprecedented collapse drove the unemployment rate to 14.7 per cent — well beyond the peak hit in late 2009 during the global financial crisis — from 4.4pc in March.

And job losses in March were worse than initially reported, falling 870,000 even though the business closures mostly happened in the second half of the month.

The plunge in non-farm payroll employment was the largest ever recorded since 1939, while the jobless rate was the highest and the biggest increase since 1948, the report said.

Employment fell sharply in all major industry sectors, with particularly heavy job losses in leisure and hospitality, the first sector hit and the one bearing the brunt of the impact of the lockdowns.

However, the labour department noted that the some workers were misclassified in the report as employed when they should have been counted as laid off.

Had they been listed properly, the unemployment rate would have been nearly five percentage points higher.

Meanwhile, US President Donald Trump downplayed unprecedented US job losses, saying they were not a surprise.

“It's fully expected, there's no surprise. Somebody said, 'oh look at this,'” he said on Fox News minutes after the labour department published the figures.

“I'll bring it back,” he said.

This paper documents the Chair's Summary of the Development Effectiveness Committee (DEC) discussion held on 14 April 2020. The commitee discussed the 2019 Development Effectiveness Review (DEfR), and the 2019 Annual Portfolio Performance Report (APPR).

MicroSolutions March/April 2017

MicroSolutions March/April 2018

Stamford, CT, Feb. 3, 2020 -- HARMAN, a wholly-owned subsidiary of Samsung Electronics Co., Ltd., focused on connected technologies and solutions for automotive, consumer and enterprise markets, today announced that Dinesh Paliwal will step down on April...

The latest figures from the Labor Department released on Friday showed the U.S. economy losing 20.5 million jobs in April, the steepest plunge in payrolls since the Great Depression. Colette Luke has more.

Global hedge funds posted their biggest monthly gain in more than a decade in April when stocks rocketed higher with the help of government rescue packages designed to fuel growth stalled by the...

Across the world, new roads, railways, dams and power lines are encroaching on previously virgin territory – with untold consequences for Earth’s wildlife

Our top photos from the past month.

The latest figures from the Labor Department released on Friday showed the U.S. economy losing 20.5 million jobs in April, the steepest plunge in payrolls since the Great Depression. Colette Luke has more.

Title: Health Highlights: April 26, 2010
Category: Health News
Created: 4/26/2010 12:10:00 PM
Last Editorial Review: 4/27/2010 12:00:00 AM

Title: Health Highlights: April 27, 2010
Category: Health News
Created: 4/27/2010 12:10:00 PM
Last Editorial Review: 4/28/2010 12:00:00 AM

Title: Health Highlights: April 28, 2010
Category: Health News
Created: 4/28/2010 12:10:00 PM
Last Editorial Review: 4/29/2010 12:00:00 AM

Title: Health Highlights: April 29, 2010
Category: Health News
Created: 4/29/2010 12:10:00 PM
Last Editorial Review: 4/30/2010 12:00:00 AM

Title: Health Highlights: April 27, 2012
Category: Health News
Created: 4/27/2012 2:05:00 PM
Last Editorial Review: 4/30/2012 12:00:00 AM

Title: Health Highlights: April 30, 2012
Category: Health News
Created: 4/30/2012 2:05:00 PM
Last Editorial Review: 5/1/2012 12:00:00 AM

Title: Got Unwanted Pills? Drug Take-Back Day Is April 30
Category: Health News
Created: 4/28/2016 12:00:00 AM
Last Editorial Review: 4/28/2016 12:00:00 AM

Title: Lexapro (escitalopram)
Category: Medications
Created: 3/16/2003 12:00:00 AM
Last Editorial Review: 2/24/2020 12:00:00 AM

Objective

To determine the contributions of apraxia of speech (AOS) and anomia to conversational dysfluency.

Glucagon-like peptide-2 (GLP-2) agonists have therapeutic potential in clinical indications in which the integrity or absorptive function of the intestinal mucosa is compromised, such as in short bowel syndrome (SBS). Native hGLP-2, a 33–amino acid peptide secreted from the small intestine, contributes to nutritional absorption but has a very short half-life because of enzymatic cleavage and renal clearance and thus is of limited therapeutic value. The GLP-2 analog teduglutide (Revestive/Gattex; Shire Inc.) has been approved for use in SBS since 2012 but has a once-daily injection regimen. Pharmacokinetic (PK) and pharmacodynamic studies confirm that apraglutide, a novel GLP-2 analog, has very low clearance, long elimination half-life, and high plasma protein binding compared with GLP-2 analogs teduglutide and glepaglutide. Apraglutide and teduglutide retain potency and selectivity at the GLP-2 receptor comparable to native hGLP-2, whereas glepaglutide was less potent and less selective. In rat intravenous PK studies, hGLP-2, teduglutide, glepaglutide, and apraglutide had clearances of 25, 9.9, 2.8, and 0.27 ml/kg per minute, respectively, and elimination half-lives of 6.4, 19, 16, and 159 minutes, respectively. The unique PK profile of apraglutide administered via intravenous and subcutaneous routes was confirmed in monkey and minipig and translated into significantly greater in vivo pharmacodynamic activity, measured as small intestinal growth in rats. Apraglutide showed greater intestinotrophic activity than the other peptides when administered at less-frequent dosing intervals because of its prolonged half-life. We postulate that apraglutide offers several advantages over existing GLP-2 analogs and is an excellent candidate for the treatment of gastrointestinal diseases, such as SBS.

Augmented, Virtual, and other mixed reality technologies are rapidly emerging and advancing, creating new and exciting opportunities for training and education. XR for Learning Weekly […]

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