protect Mother cow protecting her offspring By www.abc.net.au Published On :: Tue, 24 Sep 2019 07:14:00 +1000 Full Article ABC Goulburn Murray goulburnmurray Human Interest:All:All Human Interest:Animals:All Rural:All:All Rural:Livestock:All Rural:Veterinary Medicine:All Science and Technology:Animals:All Australia:VIC:Bonang 3888
protect Traditional owners call for extra protection under proposed Limmen Bight Marine Park plan By www.abc.net.au Published On :: Tue, 17 Sep 2019 18:21:00 +1000 As the NT Government releases its new management plan for the Limmen Bight Marine Park, traditional owners are pleading for far greater environmental protections and an end to overfishing in the area. Full Article ABC Radio Darwin darwin Community and Society:All:All Community and Society:Indigenous (Aboriginal and Torres Strait Islander):Aboriginal Community and Society:Indigenous (Aboriginal and Torres Strait Islander):All Environment:All:All Environment:Conservation:All Environment:Conservation:Marine Parks Environment:Environmental Impact:All Environment:Environmental Management:All Environment:Environmental Policy:All Government and Politics:Forms of Government:All Australia:NT:All Australia:NT:Darwin 0800
protect ICAC calls for better whistleblower protections in Northern Territory By www.abc.net.au Published On :: Mon, 21 Oct 2019 10:36:00 +1100 An "extremely disturbing" trend of Northern Territory Government workers facing "reprisals" for raising concerns about corruption or improper conduct triggers a call for the region's whistleblower laws to be strengthened. Full Article ABC Radio Darwin alicesprings darwin katherine Government and Politics:Forms of Government:All Law Crime and Justice:Corruption:All Australia:NT:Alice Springs 0870 Australia:NT:Darwin 0800 Australia:NT:Katherine 0850 Australia:NT:Nhulunbuy 0880 Australia:NT:Tennant Creek 0860
protect Territory Families records fewer child protection notifications and closes fewer investigations By www.abc.net.au Published On :: Fri, 25 Oct 2019 08:05:00 +1100 The Territory Families Department finalised half the number of child-protection investigations it planned to last financial year, but child welfare advocates say the figure is a result of longer-term reforms. Full Article ABC Radio Darwin darwin Community and Society:All:All Community and Society:Child Abuse:All Health:Child Health and Behaviour:All Law Crime and Justice:Crime Prevention:All Australia:NT:All Australia:NT:Darwin 0800
protect Victorian man who posted asbestos to foreign embassies wanted to 'protect firefighters' By www.abc.net.au Published On :: Fri, 06 Sep 2019 11:39:00 +1000 A Victorian man who sent 52 packages filled with asbestos to embassies in Sydney, Melbourne and Canberra has been sentenced to one year in prison. Full Article ABC Radio Canberra canberra sydney melbourne shepparton Government and Politics:Forms of Government:All Health:Asbestos:All Law Crime and Justice:Courts and Trials:All Law Crime and Justice:Crime:All Australia:ACT:Canberra 2600 Australia:NSW:Sydney 2000 Australia:VIC:Melbourne 3000 Australia:VIC:Shepparton 3630
protect Gardeners to face backyard blitz on netting with new laws proposed to protect wildlife By www.abc.net.au Published On :: Sat, 14 Sep 2019 06:00:00 +1000 Backyard gardeners could face fines of almost $2,500 if they are not careful when covering their fruit trees or vegetable gardens with netting. Full Article ABC Radio Canberra canberra melbourne Government and Politics:Federal Government:All Law Crime and Justice:Animal Welfare:All Lifestyle and Leisure:All:All Lifestyle and Leisure:Gardening:All Rural:Agricultural Policy:All Rural:All:All Australia:ACT:Parliament House 2600 Australia:All:All Australia:VIC:Melbourne 3000
protect Bullying and violence inquiry into Canberra schools backs protection orders, social workers By www.abc.net.au Published On :: Fri, 20 Sep 2019 17:25:00 +1000 A parliamentary inquiry into how Canberra schools handle bullying complaints reveals tragic stories of desperate parents and students, prompting a raft of recommendations. Full Article ABC Radio Canberra canberra Education:All:All Education:Bullying:All Education:Schools:All Education:Schools:Primary Schools Education:Schools:Public Schools Education:Schools:Secondary Schools Australia:ACT:All Australia:ACT:Canberra 2600 Australia:All:All
protect Honda lashes out over 'disappointing' mandatory roll bar protection for quad bikes By www.abc.net.au Published On :: Thu, 10 Oct 2019 15:24:00 +1100 Quad bike manufacturer Honda has described the Government's new roll bar rules as a "ban by stealth" and says that today is a "disappointing day for farm safety". Full Article ABC Radio Canberra canberra westernplains sydney darwin katherine northqld brisbane adelaide northandwest hobart northtas gippsland melbourne shepparton northwestwa perth Government and Politics:All:All Government and Politics:Federal Government:All Health:Occupational Health and Safety:All Health:safety:All Rural:Agribusiness:All Rural:Agricultural Policy:All Rural:Farm Labour:All Australia:ACT:Parliament House 2600 Australia:All:All Australia:NSW:Dubbo 2830 Australia:NSW:Sydney 2000 Australia:NT:Darwin 0800 Australia:NT:Katherine 0850 Australia:QLD:Bowen 4805 Australia:QLD:Brisbane 4000 Australia:SA:Adelaide 5000 Australia:SA:Port Pirie 5540 Australia:TAS:Hobart 7000 Australia:TAS:Launceston 7250 Australia:VIC:Bairnsdale 3875 Australia:VIC:Melbourne 3000 Australia:VIC:Shepparton 3630 Australia:WA:Karratha 6714 Australia:WA:Perth 6000
protect Great Barrier Reef protection laws see farmers rally against agricultural run-off limits in Townsville By www.abc.net.au Published On :: Tue, 03 Sep 2019 18:40:00 +1000 Hundreds of farmers have rallied in Queensland to protest against proposed new laws to protect the Great Barrier Reef, saying they are being treated as "guilty until proven innocent". Full Article ABC Far North widebay farnorth tropic northqld Environment:Environmental Impact:All Environment:Oceans and Reefs:Great Barrier Reef Government and Politics:All:All Rural:Agribusiness:All Rural:Agricultural Crops:All Rural:Agricultural Crops:Bananas Rural:Agricultural Crops:Sugar Australia:QLD:Bundaberg 4670 Australia:QLD:Cairns 4870 Australia:QLD:Mackay 4740 Australia:QLD:Proserpine 4800 Australia:QLD:Townsville 4810
protect Traffic controller who witnessed wife's death at work wants better protection for road workers By www.abc.net.au Published On :: Mon, 19 Aug 2019 16:37:00 +1000 What began as a great adventure led to the worst day of Colin Caudell's life as he watched a truck run over his wife while she was working as a traffic controller. Full Article ABC Capricornia sunshine capricornia Disasters and Accidents:Accidents:All Disasters and Accidents:Accidents:Workplace Health:Occupational Health and Safety:All Australia:QLD:All Australia:QLD:Maroochydore 4558 Australia:QLD:Rockhampton 4700
protect LawArXiv Papers | Analysis of the NHSX Contact Tracing App ‘Isle of Wight’ Data Protection Impact Assessment By osf.io Published On :: 2020-05-09T11:13:41+00:00 This note examines the published data protection impact assessment (DPIA) released by NHSX in relation to their contact tracing/proximity tracing app. It highlights a range of significant issues which leave the app falling short of data protection legislation. It does this in order so that these issues can be remedied before the next DPIA is published. Full Article
protect S. California Alliance of Publicly Owned Treatment Works v. US Environtmental Protection Agency By feeds.findlaw.com Published On :: 2017-04-12T08:00:00+00:00 (United States Ninth Circuit) - In a petition for review challenging an Objection Letter sent by the EPA regarding draft permits for water reclamation plants in El Monte and Pomona, California, the petition is dismissed for lack of subject matter jurisdiction where neither 33 U.S.C. section 1369(b)(1)(E) nor (F) of the Clean Water Act provided the court with subject matter jurisdiction to review the Objection Letter. Full Article Public Utilities Water Law Administrative Law Environmental Law
protect Alarm Detection Systems, Inc. v. Orlando Fire Protection District By feeds.findlaw.com Published On :: 2019-07-15T08:00:00+00:00 (United States Seventh Circuit) - District court's granting of summary judgment and bench verdict for Defendant affirmed. Sherman Act claim fails where the only current feasible way to comply with Chicagoland area city commercial fire safety ordinances was to use an exclusive provider. Under Fisher v. City of Berkeley, government restraints on trade imposed unilaterally do not form the basis of a Section 1 or Section 2 claim. Full Article Antitrust & Trade Regulation Government Contracts
protect Califonia Communities Against Toxics v. Environmental Protection Agency By feeds.findlaw.com Published On :: 2019-07-02T08:00:00+00:00 (United States DC Circuit) - Petition for review denied. The EPA did not act contrary to the Resource Conservation and Recovery Act in adopting a Transfer-Based Exclusion because hazardous materials are not necessarily "discarded" when they are transferred from a generator to a reclaimer along with payment. The policy was not arbitrary or capricious. Full Article Government Law Environmental Law
protect Delaware Riverkeeper Network v. Pennsylvania Department of Environmental Protection By feeds.findlaw.com Published On :: 2018-09-04T08:00:00+00:00 (United States Third Circuit) - Denied a petition for review of a Pennsylvania state regulators' decision to grant a Clean Water Act certification to a natural gas pipeline project. An environmental organization raised various procedural and substantive arguments against the environmental regulators' issuance of a water quality certification. On judicial review, the Third Circuit held that the environmentalists' challenge failed on the merits. Prior to reaching the merits, the panel discussed in detail questions regarding its jurisdiction under the Natural Gas Act. Full Article Water Law Environmental Law Oil and Gas Law
protect EOR Energy, LLC v. Illinois Environmental Protection Agency By feeds.findlaw.com Published On :: 2019-01-16T08:00:00+00:00 (United States Seventh Circuit) - Held that an energy company could not proceed with its claim that Illinois environmental regulators lacked jurisdiction over its handling of hazardous‐waste acid that it transported into the state. Affirmed a dismissal based on claim and issue preclusion, among other doctrines. Full Article Environmental Law Oil and Gas Law Civil Procedure
protect Califonia Communities Against Toxics v. Environmental Protection Agency By feeds.findlaw.com Published On :: 2019-07-02T08:00:00+00:00 (United States DC Circuit) - Petition for review denied. The EPA did not act contrary to the Resource Conservation and Recovery Act in adopting a Transfer-Based Exclusion because hazardous materials are not necessarily "discarded" when they are transferred from a generator to a reclaimer along with payment. The policy was not arbitrary or capricious. Full Article Government Law Environmental Law
protect Quigley v. Garden Valley Fire Protection Dist. By feeds.findlaw.com Published On :: 2019-07-15T08:00:00+00:00 (Supreme Court of California) - Reversed and remanded. The Government Claims Act immunity for public entities is an affirmative defense that can be waived or forfeited if not timely raised. Full Article Government Law Civil Procedure
protect RNC Launches 'Protect the Vote' to Fight Left's Vote-by-Mail Scheme By feedproxy.google.com Published On :: Fri, 08 May 2020 19:55:04 +0000 The Republican National Committee (RNC) launched a digital platform on Friday called "Protect the Vote" as a response to the left's increasing attempts to use the coronavirus pandemic to push their election agenda items, such as universal mail-in voting. Full Article 2020 Election Politics Joe Biden Marc Elias Nancy Pelosi Protect the Vote Republican National Committee RNC Ronna McDaniel vote by mail voter fraud
protect Hungary: 'Yes to Protecting Women, No to Gender Ideology, Illegal Migration' By feedproxy.google.com Published On :: Sat, 09 May 2020 08:44:16 +0000 Hungary's parliament has passed a declaration against signing the Istanbul Convention on preventing and combating violence against women because it smuggles in provisions declaring gender a "social construct" and allowing "gender-based asylum claims". Full Article London / Europe Politics Social Justice Council Of Europe gender gender identity gender politics globalism Hungary Identity Politics Illegal Aliens illegal immigration Istanbul Convention Mass Migration Migrant Crisis Migrants SJWs social justice warriors V4 Viktor Orbán Visegrad women Zoltán Kovács
protect Quigley v. Garden Valley Fire Protection Dist. By feeds.findlaw.com Published On :: 2019-07-15T08:00:00+00:00 (Supreme Court of California) - Reversed and remanded. The Government Claims Act immunity for public entities is an affirmative defense that can be waived or forfeited if not timely raised. Full Article Government Law Civil Procedure
protect Consumer Financial Protection Bureau v. Seila Law LLC By feeds.findlaw.com Published On :: 2019-05-06T08:00:00+00:00 (United States Ninth Circuit) - Held that the U.S. Consumer Financial Protection Bureau's structure is constitutionally permissible. A law firm raised the argument in contending that it was not required to comply with the bureau's investigative demand to respond to interrogatories about its debt relief services and marketing. The Ninth Circuit rejected the law firm's position. Full Article Debt Collection Banking Law Consumer Protection Law
protect Users are urged to get malware protection immediately By feedproxy.google.com Published On :: Thu, 10 Oct 2012 21:53:51 GMT Due to a sharp increase in malware related spam, we urge everyone to make sure that their computers are adequately protected against malware attacks. If you don't have protection against malware, we strongly suggest an Internet Security suite. Feel free to contact us if you need any information about malware protection. You might also want for check out the latest examples of malware spam e-mails. Full Article
protect Help, protection sought for Colorado’s immigrants amid pandemic By feeds.denverpost.com Published On :: Sat, 09 May 2020 12:00:25 +0000 Immigrant advocates are working with Colorado lawmakers to provide relief to vulnerable families during the coronavirus crisis. Full Article Colorado Legislature Colorado News Colorado Politics Immigration News Politics Colorado General Assembly coronavirus coronavirus in Colorado immigration Immigration and Customs Enforcement
protect Delaware Riverkeeper Network v. Pennsylvania Department of Environmental Protection By feeds.findlaw.com Published On :: 2018-09-04T08:00:00+00:00 (United States Third Circuit) - Denied a petition for review of a Pennsylvania state regulators' decision to grant a Clean Water Act certification to a natural gas pipeline project. An environmental organization raised various procedural and substantive arguments against the environmental regulators' issuance of a water quality certification. On judicial review, the Third Circuit held that the environmentalists' challenge failed on the merits. Prior to reaching the merits, the panel discussed in detail questions regarding its jurisdiction under the Natural Gas Act. Full Article Water Law Environmental Law Oil and Gas Law
protect Help, protection sought for Colorado’s immigrants amid pandemic By www.denverpost.com Published On :: Sat, 09 May 2020 12:00:25 +0000 Immigrant advocates are working with Colorado lawmakers to provide relief to vulnerable families during the coronavirus crisis. Full Article Colorado Legislature Colorado News Colorado Politics Immigration News Politics Colorado General Assembly coronavirus coronavirus in Colorado immigration Immigration and Customs Enforcement
protect Editorial: Protect those essential employees By feeds.denverpost.com Published On :: Wed, 01 Apr 2020 22:41:53 +0000 Employees on the front-lines of the coronavirus pandemic are truly essential. Employers must treat them as such. Full Article Editorials Opinion CDC City Market coronavirus doctors grocery stores hospital jobs King Soopers Kroger manufacturing nurses Safeway White House
protect UK Music Proposes Law To Protect Music Venues By feedproxy.google.com Published On :: New Legislation Would Protect Music Venues Threatened With Closure Full Article
protect Alarm Detection Systems, Inc. v. Orlando Fire Protection District By feeds.findlaw.com Published On :: 2019-07-15T08:00:00+00:00 (United States Seventh Circuit) - District court's granting of summary judgment and bench verdict for Defendant affirmed. Sherman Act claim fails where the only current feasible way to comply with Chicagoland area city commercial fire safety ordinances was to use an exclusive provider. Under Fisher v. City of Berkeley, government restraints on trade imposed unilaterally do not form the basis of a Section 1 or Section 2 claim. Full Article Antitrust & Trade Regulation Government Contracts
protect Neiman Marcus becomes 2nd major retailer to seek Chapter 11 bankruptcy protection By www.denverpost.com Published On :: Thu, 07 May 2020 18:09:12 +0000 Neiman Marcus has filed for Chapter 11 bankruptcy protection, the first department store chain and second major retailer to be toppled by the coronavirus pandemic. Full Article Business Latest News News Retail bankruptcy coronavirus department stores economic impact of coronavirus health Neiman Marcus
protect Neiman Marcus becomes 2nd major retailer to seek Chapter 11 bankruptcy protection By feeds.denverpost.com Published On :: Thu, 07 May 2020 18:09:12 +0000 Neiman Marcus has filed for Chapter 11 bankruptcy protection, the first department store chain and second major retailer to be toppled by the coronavirus pandemic. Full Article Business Latest News News Retail bankruptcy coronavirus department stores economic impact of coronavirus health Neiman Marcus
protect WATCH: MSU Denver uses 3D printing lab to produce personal protective equipment for health care workers By www.denverpost.com Published On :: Mon, 13 Apr 2020 16:14:41 +0000 Ted Shin, the chair of the Department of Industrial Design at Metropolitan State University of Denver, could see coronavirus coming, first in China, then in Italy. Full Article Business Colorado News Denver Post TV Latest News News News Video Newsmakers Photos Technology 3-D printer coronavirus coronavirus in Colorado Metro State University video
protect Meek Mill: Call Governors, Demand Protections For Prisoners By feeds.bet.com Published On :: Thu, 26 Mar 2020 09:00:00 EDT “We need everyone's voice right now.” Full Article Meek Mill Music News
protect Secret Service Agent Talks About Protecting Michelle Obama By feeds.bet.com Published On :: Thu, 7 May 2020 15:44:00 EDT He gave a rare interview for “Becoming.” Full Article National News
protect Sewing Teen Producing Protective Masks For Frontline Workers By feeds.bet.com Published On :: Thu, 30 Apr 2020 09:20:00 EDT Darius Brown wants to help protect hospital workers Full Article National News
protect Secret Service Agent Talks About Protecting Michelle Obama By feeds.bet.com Published On :: Thu, 7 May 2020 15:44:00 EDT He gave a rare interview for “Becoming.” Full Article National News
protect Sandra Bullock Wants to Protect Black Son ‘In a Bubble’ By feeds.bet.com Published On :: Wed, 7 Oct 2015 17:45:00 EDT She expresses concern over son's safety in this "mad world." Full Article Adoption Black Youth Celebrity Style News celebrity baby Parenting Motherhood black boys
protect Legitsu To Host “Embrace Protect & Connect” By bernews.com Published On :: Thu, 23 Jan 2020 10:42:45 +0000 Legitsu Academy is getting set to host “Embrace Protect & Connect” on Saturday, February 15th from 4.30pm to 6.00pm. The event poster says, “Bring anyone you love and share the gift of movement through self defence, acro yoga and Thai massage. “Saturday, February 15th from 4.30pm to 6.00pm at Legitsu Academy, [Old Berkeley School/ Cultural […](Click to read the full article) Full Article All Sports #MartialArts
protect HSBC’s Credit Card Alerts Offer Fraud Protection By bernews.com Published On :: Wed, 13 Nov 2019 13:12:14 +0000 HSBC is introducing credit card alerts to assist in protecting customers against fraud. A spokesperson said, “With over $5 billion in card related fraud losses being reported globally in 2019, every card holder should be aware of the importance of keeping their card data safe. “One of HSBC’s top priorities is to find ways to […](Click to read the full article) Full Article All Business technology #BermudaBanks #HSBCBank
protect Fishing In Seasonally Protected Areas Prohibited By bernews.com Published On :: Thu, 05 Apr 2018 14:38:17 +0000 The Ministry of Home Affairs is reminding commercial and recreational fishers, that fishing in the Seasonally Protected Areas — also known as the “Hind Grounds” and “Grouper Grounds” — will be prohibited from 15 April to 14 August 2018 in order to protect spawning Red Hinds and Black Groupers. “It should also be noted that […](Click to read the full article) Full Article All Environment News #BermudaMarine #Fishing
protect ‘Protecting Our Planet & The Public Purse’ By bernews.com Published On :: Tue, 10 Mar 2020 17:00:58 +0000 Guy Carpenter has released a new report: Protecting Our Planet & The Public Purse, which highlights how the “risk landscape for public sector entities is changing at an unparalleled rate.” A spokesperson said, “Severe weather events and demographic challenges are putting an increasing strain on government finances, requiring a rethink of how catastrophic events are […](Click to read the full article) Full Article All Business Environment #BermudaBusiness #ClimateChange
protect OBA’s Smith: ‘Police Budget Must Be Protected’ By bernews.com Published On :: Thu, 20 Feb 2020 13:18:57 +0000 “Following the recent spate of shootings, the police budget must be protected if they are to be able to combat gang crime,” Shadow National Security Minister Ben Smith said today. Mr. Smith said, “Recently, I expressed my concerns about reports reaching me that the Bermuda Police Service budget could be cut by as much as […](Click to read the full article) Full Article All News Politics #BermudaPolice #BermudaPolitics #Shootings
protect Featured Centennial Paper - TRB’s Role in Transportation Infrastructure Protection and Resilience By www.trb.org Published On :: Fri, 08 May 2020 06:39:14 GMT Standing Technical Committee on Critical Transportation Infrastructure got its start as the Task Force on Critical Transportation Infrastructure Security tied directly in response to the Presidential Decision Directive 63, Critical Infrastructure Protection (PPD-63). Soon after the task force was established, as a way to bring awareness to this topic, TRB published a special edition of TR News (211): Transportation Security: Protecting the System from Attack and Theft (November-December 2000). The editio... Full Article
protect Protecting Yourself Against COVID-19 By teenhealthandwellness.com Published On :: Mon, 23 Mar 2020 12:49:30 -0400 As more COVID-19 outbreaks are reported around the world, it’s important to stay calm, be informed, and take steps to protect yourself and others. Although older and chronically ill adults face greater risks, teens and young adults are also facing serious health complications from COVID-19. Dr. Anthony Fauci, the head of the U.S. National Institute of Allergy and Infectious Diseases, said, “Don’t get the attitude, ‘Well, I’m young, I’m invulnerable’ ... you don’t want to put your loved ones at risk, particularly the ones who are elderly and the ones who have compromised conditions. We can’t do this without the young people cooperating. Please cooperate with us.” While there is currently no vaccine against COVID-19, there are things you can do to take care of your health. Avoid touching your eyes, nose, and mouth. Wash your hands frequently with soap and water for at least 20 seconds (the time it takes to sing “Happy Birthday” twice). Dry your hands thoroughly after washing them. If soap and water aren’t available, use an alcohol-based hand sanitizer. Cleaning and disinfecting surfaces that are commonly used by people can help, too. The U.S. Environmental Protection Agency (EPA) has released a list of approved disinfectants to help protect against the spread of COVID-19 on their website. Full Article
protect Protecting Children - B.S.A.'s Top Priority By www.scoutscapecod.org Published On :: Wed, 01 May 2019 09:17:53 -0400 Every adult leader must complete an extensive Youth Protection Training program. ... Full Article
protect Exosome-mediated protection of auditory hair cells from ototoxic insults By www.jci.org Published On :: Hearing loss caused by the death of sensory hair cells of the inner ear is an unfortunate side effect for many patients treated with aminoglycoside antibiotics or platinum-containing chemotherapy agents. In animal models, induction of heat shock confers substantial otoprotection against aminoglycoside- and cisplatin-induced hair cell death. In this issue of the JCI, Breglio et al. demonstrate that inner ear tissue released exosomes carrying heat shock protein 70 (HSP70) in response to heat stress. HSP70 acted by a paracrine mechanism that engaged the Toll-like receptor 4 (TLR4) on hair cells to protect them from death. Exosomes and the HSP70/TLR4 pathway could thus provide treatment targets for the protection of hair cells from chemically induced death or from other insults, such as noise. Full Article
protect Exosomes mediate sensory hair cell protection in the inner ear By www.jci.org Published On :: Hair cells, the mechanosensory receptors of the inner ear, are responsible for hearing and balance. Hair cell death and consequent hearing loss are common results of treatment with ototoxic drugs, including the widely used aminoglycoside antibiotics. Induction of heat shock proteins (HSPs) confers protection against aminoglycoside-induced hair cell death via paracrine signaling that requires extracellular heat shock 70-kDa protein (HSP70). We investigated the mechanisms underlying this non–cell-autonomous protective signaling in the inner ear. In response to heat stress, inner ear tissue releases exosomes that carry HSP70 in addition to canonical exosome markers and other proteins. Isolated exosomes from heat-shocked utricles were sufficient to improve survival of hair cells exposed to the aminoglycoside antibiotic neomycin, whereas inhibition or depletion of exosomes from the extracellular environment abolished the protective effect of heat shock. Hair cell–specific expression of the known HSP70 receptor TLR4 was required for the protective effect of exosomes, and exosomal HSP70 interacted with TLR4 on hair cells. Our results indicate that exosomes are a previously undescribed mechanism of intercellular communication in the inner ear that can mediate nonautonomous hair cell survival. Exosomes may hold potential as nanocarriers for delivery of therapeutics against hearing loss. Full Article
protect IL-17–producing γδ T cells protect against Clostridium difficile infection By www.jci.org Published On :: Colitis caused by Clostridium difficile infection is a growing cause of human morbidity and mortality, especially after antibiotic use in health care settings. The natural immunity of newborn infants and protective host immune mediators against C. difficile infection are not fully understood, with data suggesting that inflammation can be either protective or pathogenic. Here, we show an essential role for IL-17A produced by γδ T cells in host defense against C. difficile infection. Fecal extracts from children with C. difficile infection showed increased IL-17A and T cell receptor γ chain expression, and IL-17 production by intestinal γδ T cells was efficiently induced after infection in mice. C. difficile–induced tissue inflammation and mortality were markedly increased in mice deficient in IL-17A or γδ T cells. Neonatal mice, with naturally expanded RORγt+ γδ T cells poised for IL-17 production were resistant to C. difficile infection, whereas elimination of γδ T cells or IL-17A each efficiently overturned neonatal resistance against infection. These results reveal an expanded role for IL-17–producing γδ T cells in neonatal host defense against infection and provide a mechanistic explanation for the clinically observed resistance of infants to C. difficile colitis. Full Article
protect The SEBAC agreement is the mother of all can-kicks a sweetheart deal protected by contract for a full decade By www.cpa-connecticut.com Published On :: Mon, 02 Oct 2017 19:34:00 +0000 The sweetheart deal that Governor Malloy and his fellow Democrats in the General Assembly cut with state employee unions, the so-called SEBAC agreement, is protected by contract for a full decade —leaving meaningful reforms waaay down the road. The contract is the mother of all can-kicks. Continue reading → Full Article Accountants CPA Hartford Articles Connecticut union concession bill Democrat GOP budget Governor Malloy Joe Aresimowicz kicking the can down the road Republican SEBAC agreement spiking state employee unions The SEBAC agreement is the mother of all can-kicks The SEBAC agreement is the mother of all can-kicks a sweetheart deal protected by contract for a full decade
protect IBM Achieves Major Climate Protection Goals Four Years Early By www.ibm.com Published On :: Fri, 23 Jun 2017 10:19:34 GMT Today, IBM announced that it achieved two major commitments four years ahead of schedule in its effort to help combat climate change. Full Article Smarter Planet