At 85, Dame Judi Dench has made history as the oldest person ever to star on the cover of Vogue magazine. The veteran actress looked striking on the cover of British Vogue and we couldn't take eyes off her.

While the city was on lockdown between March 23 and May 4, ACS received 3,855 new allegations of child neglect and abuse — 4,496 fewer cases than the 8,351 taken in by the child welfare agency at the same time last year.

With the UK government set to tighten its lockdown restrictions, fresh doubts have been cast over the viability of a British Grand Prix.

The Undertaker has revealed all over his injury hell, crippling doubts over his ability as he gets older and his biggest fears in a stunning tell-all documentary.

Damon Hill is no longer sure former drivers should be acting as full FIA stewards at grands prix

“If He holds back the waters, there is drought; if He lets them loose, they devastate the land”. To be fair, that was in the days before governments played “a key role in developing targeted policy responses to market failures that impede the mitigation and allocation of drought and flood risks”, as the OECD report on Mitigating Droughts and Floods in Agriculture puts it.

2. The Informant, a company incorporated in May, 2015, has been operating under the brand name of Treebo Hotels' and is in the business of providing franchising services to budget hotels in India. In addition to this, Treebo also provides service to numerous independent budget hotels who partner with it under its newly launched 'Hotel Superhero' scheme. Under the said scheme, Treebo only provides services such as hotel management technology services, listing on its platform and other online travel aggregators, credit facilities, support and quality control of the staff and hotel management resources etc. but does not provide its brand name.

3. MMT is an Online Travel Agency (OTA) engaged in the business of providing travel and tourism related services in India. It is a part of MakeMyTrip group of companies (MMT Group). OYO, on the other hand, provides budget accommodation to customers and is in the market for providing franchising services to budget hotels under the brand name 'OYO'.

After winning a third global heptathlon title on Sunday, surely cementing her status as Britain's greatest female athlete, Jessica Ennis-Hill thanked her 'team' for their unwavering support since childbirth.

MARTHA KELNER: The 29-year-old spoke passionately about feeling betrayed by the very people she should have been able to trust to protect her as a clean athlete.

CHRIS FOY IN MIYAZAKI: The 21-year-old joined several of his team-mates for paddle-boarding, to continue this phase of tough training and valuable down-time.

As part of the Virus-X Consortium that aims to identify and characterize novel proteins and enzymes from bacteriophages and archaeal viruses, the genes of the putative lytic proteins XepA from Bacillus subtilis prophage PBSX and YomS from prophage SPβ were cloned and the proteins were subsequently produced and functionally characterized. In order to elucidate the role and the molecular mechanism of XepA and YomS, the crystal structures of these proteins were solved at resolutions of 1.9 and 1.3 Å, respectively. XepA consists of two antiparallel β-sandwich domains connected by a 30-amino-acid linker region. A pentamer of this protein adopts a unique dumbbell-shaped architecture consisting of two discs and a central tunnel. YomS (12.9 kDa per monomer), which is less than half the size of XepA (30.3 kDa), shows homology to the C-terminal part of XepA and exhibits a similar pentameric disc arrangement. Each β-sandwich entity resembles the fold of typical cytoplasmic membrane-binding C2 domains. Only XepA exhibits distinct cytotoxic activity in vivo, suggesting that the N-terminal pentameric domain is essential for this biological activity. The biological and structural data presented here suggest that XepA disrupts the proton motive force of the cytoplasmatic membrane, thus supporting cell lysis.

Women's cheeks get redder when they are the most fertile, but this color change is so subtle that it is undetectable by the human eye.

Visit Steve Sauer's Seattle apartment, a 182-square-foot storage unit transformed into a cozy dwelling.

Advanced refrigeration system, nearly a mile long, is meant to keep contaminated water from the damaged nuclear plant from escaping into the sea.

This is the first photograph ever taken of the bizarre and mysterious species, Thismia neptunis.

A guild of artisans is preserving traditional weaving methods in a region of Peru overshadowed by the ruins of Machu Picchu.

Alexandra Cousteau revisits Scott St. Pierre in Louisiana and learns how he and others are coping with the oil spill.

Bizarre fish has evolved fins like no other and is capable of walking like a land animal.

An excerpt from the Climate Reality Project compares today's argument about climate change to the '60s argument over cigarettes.

Al Gore's 24-hour Climate Reality broadcast has attracted millions of online viewers. A competing broadcast by climate doubters had just thousands.

Bob Sutton, Stanford University professor and author of "The No Asshole Rule."

Patterns can be a powerful way to quickly add some real texture to your artwork with very minimal effort. In one-click you have beautiful texture overlays that will...

The post Seamless Vector Subtle Grunge Patterns appeared first on Function Design Blog.

During VR demos we have performed over last few years, many participants (in the absence of any haptic feedback) have commented on their perceived ability to 'feel' differences between simulated molecular objects. The mechanisms for such 'feeling' are not entirely clear: observing from outside VR, one can see that there is nothing physical for participants to 'feel'. Here we outline exploratory user studies designed to evaluate the extent to which participants can distinguish quantitative differences in the flexibility of VR-simulated molecular objects. The results suggest that an individual's capacity to detect differences in molecular flexibility is enhanced when they can interact with and manipulate the molecules, as opposed to merely observing the same interaction. Building on these results, we intend to carry out further studies investigating humans' ability to sense quantitative properties of VR simulations without haptic technology.

An α-amylase from Bacillus subtilis (AmyE) produces significant amounts of glucose from various carbohydrate substrates, including vegetable starch, maltoheptaose, and maltotriose. Among other things, this advantageous property allows AmyE or variants thereof to be used in a saccharification reaction having a reduced or eliminated requirement for glucoamylase. The reduction or elimination of the glucoamylase requirement significantly improves the efficiency of the production of ethanol or high fructose corn syrup, for example.

A computer-implemented method, system, and computer program product are disclosed for updating simulation models of a subterranean reservoir. An ensemble of reservoir models representing a subterranean reservoir having non-Gaussian characteristics is provided and the ensemble of reservoir models is updated using a subspace ensemble Kalman filter. Kemal principle component analysis parameterization or K-L expansion parameterization can be used to update the ensemble of reservoir models.

Methods for creating and using space-time surrogate models of subsurface regions, such as subsurface regions containing at least one hydrocarbon formation. The created surrogate models are explicit models that may be created from implicit models, such as computationally intensive full-physics models. The space-time surrogate models are parametric with respect to preselected variables, such as space, state, and/or design variables, while also indicating responsiveness of the preselected variables with respect to time. In some embodiments, the space-time surrogate model may be parametric with respect to preselected variables as well as to time. Methods for updating and evolving models of subsurface regions are also disclosed.

An information storage medium storing subtitle text-based information, and a method and apparatus utilizing same, process a subtitle The information storage medium includes: dialog information which contains script text information of the subtitle and information specifying an output type of the script text; and presentation information which contains style information used to convert the script text into a bitmap format through rendering. With this structure, the amount of data required for a subtitle and the amount of data that should be processed when a subtitle is output may be greatly reduced.

An educational game for teaching addition and subtraction of whole numbers includes a carpet/game board including ten positively numbered spaces from +1 to +10 inclusive a 0 space and negatively numbered spaces from −1 to −10 inclusive and wherein said positive numbered spaces proceed upwardly in a generally zigzag direction from 0 to plus 10 and the negatively numbered spaces proceed downwardly from 0 to minus 10 and an extra space above the plus 10 and an extra space below the minus 10 wherein the extra space above the plus 10 is a win space and the space below the minus 10 is a lose space. The game also includes a single cube shaped die having six faces with an indication of plus 2, minus 2 and no movement on three of the faces and a plus 1, minus 1 and plus 1 plus and additional turn on the sixth face. Further, the game includes six game pieces of separate distinct colors.

Expandable apparatus for use in subterranean boreholes include at least one member configured to move between a retracted position and an extended position. A latching member disposed in the tubular body may selectively retain the at least one member in the retracted position. Methods of operating an expandable apparatus include securing at least one member of the expandable apparatus in a retracted position by engaging an inner wall of a tubular body with at least one latch member disposed in at least one aperture formed in a latch sleeve.

Expandable apparatus for use in subterranean boreholes include at least one member configured to move between a retracted position and an extended position. Components of the expandable apparatus may include at least one surface for removing debris proximate to the tubular body. Components of the expandable apparatus may be configured to enable the expandable apparatus to increase a diameter of a subterranean borehole by greater than twenty percent. Components of the expandable apparatus may be configured to restrict fluid flow to nozzle assemblies. The expandable apparatus may include a protect sleeve having a push sleeve disposed therein. Methods of operating an expandable apparatus may include removing debris with a surface of the expandable apparatus. Methods of operating an expandable apparatus may also include selectively flowing fluid to nozzle assemblies.

A rotary joint for use in directional control of a subterranean rotary steerable drilling apparatus. The rotary joint is formed by mated spherical-shaped sockets, each of which is connected with a hollow rod. By virtue of this arrangement, a continuous passageway is provided for fluid to flow through the rotary joint, which fluid may be used for cooling the rotary joint during operation of the rotary steerable drilling system.

Methods of treating a wellbore in a subterranean formation including providing an oil-external treatment fluid, wherein the oil-external treatment fluid is a 3D-network comprising a chemical interaction between a hydrocarbon fluid, an aqueous fluid, and a surface modification agent; providing proppant particulates; suspending the proppant particulates in the oil-external treatment fluid; and introducing the oil-external treatment fluid comprising the proppant particulates into the wellbore in the subterranean formation.

A production saltwater disposal facility comprising a separator configured to receive production saltwater from a pipeline or a vehicle and separate hydrocarbons from the production saltwater, wherein the production saltwater received from the pipeline or vehicle is substantially the same composition as when the production saltwater was located in a subterranean formation, a hydrocarbon storage tank configured to receive hydrocarbons from the separator, a settling pit configured to receive the production saltwater from the separator and separate metals and/or other solids from the saltwater, an evaporator in fluid communication with the settling pit and comprising a nozzle configured to emit a stream of the saltwater along a path in air such that water in the saltwater evaporates, and a collection pit positioned under the path and configured to collect the salt from the saltwater after the water has evaporated.

News you don't want to miss for April 16:

1. As if you didn't have enough to worry about, but California may be heading toward a historic drought, the type that has only occurred four times in the past 1,200 years, the San Francisco Chronicle reports.…

HARRY Redknapp has “no doubt” Cherries will steer clear of trouble – and the club’s former boss says he admires Eddie Howe’s refusal to sacrifice his footballing principles as the survival battle hots up.

Laurence Inman is not in a hopeful mood, despite receiving good news

Bed Bath and Beyond has been struggling to boost sales in the face of changing consumer preferences towards online furniture retailers such as Wayfair Inc.

Am nächsten Wochenende setzt die Fußball-Bundesliga ihre Mitte März unterbrochene Saison fort. Für den Torjubel und auch andere Abläufe im und vor dem Spiel gibt es von der Deutschen Fußball Liga exakte Vorschriften.

Matthew Panzarino returns to the show. Topics include the brand new MacBook Air and iPad Pros, and, you know, global pandemics in the internet age.

In the 1970s Monsanto unveiled a miracle herbicide–Glyphosate. The pitch: it was as safe as table salt for people, but could flatten even the peskiest weeds. Farmers and homeowners alike have used the product ever since. Now, it shows up in detectable levels in many foods, and almost every American has some in their bodies....