The OSCE Center in Bishkek and the Training Centre for Prosecutors under the General Prosecutor’s Office will conduct a training course for twenty-four public prosecution officers from all provinces of Kyrgyzstan on effective investigation of cases of torture.

The training aims at enhancing theoretical and empirical knowledge of prosecution officers about the specifics of efficient investigation of torture allegations.

The participants will discuss the key challenges arising during investigation of torture allegations and exchange best practices applied within their respective duty stations to address these challenges. 

Related Stories

• OSCE supports preventive visits of the staff of the National Centre for the Prevention of Torture to the detention facilities in Isykkul, Naryn and Talas provinces
• To mark World Day against Trafficking in Persons OSCE Centre in Bishkek supports public awareness raising campaign
• OSCE Centre in Bishkek supports summer school on topical issues of police reform

Todd Golden ran Saturday's practice after the No. 21 Gators had a day off following Thursday night's 81-60 home win against Jacksonville. He is expected to be on the sidelines when  Grambling State visits at the O'Connell Center Monday night.

GSTP-CSS - The composite source signal as a measuring signal and a summary of various investigations on speech echo cancellers

The top Reporter’s Notebooks of 2023 continue to demonstrate the interest and desire for in-depth reporting, digging out more than the tidbits, but the stories behind the news.

The post Investigations into DoD struck a chord in 2023 first appeared on Federal News Network.

The U.S. Office of Public Affairs issued a statement on 4 September 2024 regarding the seizure of 32 websites that are believed to be part of the so-called "Doppelganger" campaign.

Phishing has been around for years, yet it still proves to be a major online threat. To continue profiting, cybercriminals must continuously adapt their techniques.

An obstetrician-gynecologist has been barred from practicing at Cedars-Sinai following an investigation into complaints. The doctor has denied wrongdoing.

Here are the key takeways from The Times' yearlong investigation into the science behind magnetic resonance therapy, or MERT, as a therapy for autism.

Shares of FirstCry fell 4.5% after the GST department initiated an investigation at its Mumbai head office and Pune warehouse. The company assured normal operations, with no details on alleged violations.

For more than nine months, Twitter and Facebook have tried to dodge the intense public scrutiny involved with the investigation into Russian interference in last year's presidential election. Now they're in the spotlight. Congressional investigators are digging in on Russia's use of Facebook, Twitter and other social media companies to try to influence the 2016 campaign. And after a series of escalating complaints by the leaders of the Senate Intelligence Committee, Facebook said Thursday it was handing over the content of more than 3,000 ads believed to be linked with Moscow's attack on the election. "We support Congress in deciding how to best use this information to inform the public, and we expect the government to publish its findings when their investigation is complete," said Facebook CEO Mark Zuckerberg . And there'll be much more: The chairman of the Senate Intelligence Committee has said he wants to hold a public hearing next month on Moscow's efforts to manipulate social

Thomas Windom, a little-known federal prosecutor, is overseeing key elements of the Justice Department’s intensifying investigation into efforts to overturn the 2020 election results.

The Denver district attorney has launched an investigation into how a spreadsheet of voting system passwords ended up on the Colorado secretary of state's website earlier this year.

A recent spate of Xcel power outages across metro Denver has prompted the Colorado Public Utilities Commission to consider opening an investigation.

"Hundreds of voting machine passwords were accidentally released but what exactly was Secretary of State Jena Griswold doing to address the security breach?" -- The Denver Post Editorial Board

The listed phone number for Wyatts rings to Elite Towing. An operator who answered the phone on Tuesday said “Wyatts Towing no longer exists.”

The owners of several dilapidated apartment buildings in Aurora and Denver have faced a new threat: an investigation by the Colorado Attorney General's Office.

Video of the shocking incident went viral.

Police reportedly applied pressure to his neck.

Today marks the seventh anniversary of the murder of Patrick Dill — who was fatally shot in Pembroke in 2016 — and the police are renewing their appeal for anyone with any information to please come forward. A police spokesperson said, “Today is the seventh year anniversary of the murder of Patrick Dill. Mr. Dill […]

“Between 2021 and the present, five people have been convicted and monies seized following investigations into suspected money laundering offences,” the police said. A police spokesperson said, “Investigations by the Bermuda Police Service [BPS] Financial Crime Unit into acts of money laundering have led to a number of convictions and resulted in the seizure of […]

The police have renewed their appeal for information about the murder of Jahkoby Smith in 2017. A police spokesperson said, “Around 7:15pm on Saturday 29th July, 2017, Jahkoby Smith, was fatally stabbed after he was involved in an altercation that took place at the West End Sailboat Club, Sandys. At that time, there was a wake […]

THE SECURITY STATE HAS EXISTED SINCE THE END OF WORLD WAR II. THEY'VE BEEN OPERATING IN SECRET AND WITH NO DEMOCRATIC ACCOUNTABILITY FOR EIGHT OR NINE DECADES NOW. DWIGHT EISENHOWER WHEN HE LEFT OFFICE WARNED THE COUNTRY ABOUT THE DANGERS THAT THEY POSE. Continue reading →

The Football Association launches its own investigation into the video that appears to show Premier League referee David Coote using foul language to describe former Liverpool boss Jurgen Klopp.

The following article, ‘Blatant Weaponization’: FEMA Facing Investigations For Targeting Suffering Trump Supporters, was first published on Conservative Firing Line.

Republicans are calling for investigations, or are already launching their own, into charges that the federal government deliberately and willfully discriminated against supporters of President-elect Donald Trump following a hurricane disaster in Florida. It was the Daily Wire that initially documented how Marn’I Washington, a Federal Emergency Management Agency supervisor, instructed employees under her authority …

Continue reading ‘Blatant Weaponization’: FEMA Facing Investigations For Targeting Suffering Trump Supporters ...

Lipoprotein (a) [Lp(a)] is a well-known risk factor for cardiovascular disease, but analysis on Lp(a) and renal dysfunction is scarce. We aimed to investigate prospectively the association of serum Lp(a) with the risk of reduced renal function, and further investigated whether diabetic or hypertensive status modified such association. Six thousand two hundred and fifty-seven Chinese adults aged ≤40 years and free of reduced renal function at baseline were included in the study. Reduced renal function was defined as estimated glomerular filtration rate <60 ml/min/1.73 m². During a mean follow-up of 4.4 years, 158 participants developed reduced renal function. Each one-unit increase in log₁₀-Lp(a) (milligrams per deciliter) was associated with a 1.99-fold (95% CI 1.15–3.43) increased risk of incident reduced renal function; the multivariable-adjusted odds ratio (OR) for the highest tertile of Lp(a) was 1.61 (95% CI 1.03–2.52) compared with the lowest tertile (P for trend = 0.03). The stratified analysis showed the association of serum Lp(a) and incident reduced renal function was more prominent in participants with prevalent diabetes [OR 4.04, 95% CI (1.42–11.54)] or hypertension [OR 2.18, 95% CI (1.22–3.89)]. A stronger association was observed in the group with diabetes and high Lp(a) (>25 mg/dl), indicating a combined effect of diabetes and high Lp(a) on the reduced renal function risk. An elevated Lp(a) level was independently associated with risk of incident reduced renal function, especially in diabetic or hypertensive patients.

In eukaryotic DNA replication, DNA polymerase ε (Polε) is responsible for leading strand synthesis, whereas DNA polymerases α and δ synthesize the lagging strand. The human Polε (hPolε) holoenzyme is comprised of the catalytic p261 subunit and the noncatalytic p59, p17, and p12 small subunits. So far, the contribution of the noncatalytic subunits to hPolε function is not well understood. Using pre-steady-state kinetic methods, we established a minimal kinetic mechanism for DNA polymerization and editing catalyzed by the hPolε holoenzyme. Compared with the 140-kDa N-terminal catalytic fragment of p261 (p261N), which we kinetically characterized in our earlier studies, the presence of the p261 C-terminal domain (p261C) and the three small subunits increased the DNA binding affinity and the base substitution fidelity. Although the small subunits enhanced correct nucleotide incorporation efficiency, there was a wide range of rate constants when incorporating a correct nucleotide over a single-base mismatch. Surprisingly, the 3'→5' exonuclease activity of the hPolε holoenzyme was significantly slower than that of p261N when editing both matched and mismatched DNA substrates. This suggests that the presence of p261C and the three small subunits regulates the 3'→5' exonuclease activity of the hPolε holoenzyme. Together, the 3'→5' exonuclease activity and the variable mismatch extension activity modulate the overall fidelity of the hPolε holoenzyme by up to 3 orders of magnitude. Thus, the presence of p261C and the three noncatalytic subunits optimizes the dual enzymatic activities of the catalytic p261 subunit and makes the hPolε holoenzyme an efficient and faithful replicative DNA polymerase.

President-elect Donald Trump wants legal authorities to investigate what he said were possibly illegal rumors he is going to sell his majority stock stake in Trump Media. He claims he won't sell.

The student newspaper at duPont Manual High School in Louisville, Ky., first reported on the state's problematic police training material.

Low-intensity transcranial focused ultrasound stimulation (TUS) is a novel technique for noninvasive brain stimulation (NIBS). TUS delivered in a theta (5 Hz) burst pattern (tbTUS) induces plasticity in the human primary motor cortex (M1) for 30–60 min, showing promise for therapeutic development. Metaplasticity refers to activity-dependent changes in neural functions governing synaptic plasticity; depotentiation is the reversal of long-term potentiation (LTP) by a subsequent protocol with no effect alone. Metaplasticity can enhance plasticity induction and clinical efficacy of NIBS protocols. In our study, we compared four NIBS protocol combinations to investigate metaplasticity on tbTUS in humans of either sex. We delivered four interventions: (1) sham continuous theta burst stimulation with 150 pulses (cTBS150) followed by real tbTUS (tbTUS only), (2) real cTBS150 followed by sham tbTUS (cTBS only), (3) real cTBS150 followed by real tbTUS (metaplasticity), and (4) real tbTUS followed by real cTBS150 (depotentiation). We measured motor-evoked potential amplitude, short-interval intracortical inhibition, long-interval intracortical inhibition, intracortical facilitation (ICF), and short-interval intracortical facilitation before and up to 90 min after plasticity intervention. Plasticity effects lasted at least 60 min longer when tbTUS was primed with cTBS150 compared with tbTUS alone. Plasticity was abolished when cTBS150 was delivered after tbTUS. cTBS150 alone had no significant effect. No changes in M1 intracortical circuits were observed. Plasticity induction by tbTUS can be modified in manners consistent with homeostatic metaplasticity and depotentiation. This substantiates evidence that tbTUS induces LTP-like processes and suggests that metaplasticity can be harnessed in the therapeutic development of TUS.

Ontario Provincial Police (OPP) have released dashcam footage of a crash that sent two people to hospital in life-threatening condition, linked to an ongoing investigation into rocks being thrown at moving vehicles in the GTA.

A New Castle County grand jury has indicted a New Castle woman for 53 felonies following the alleged murder of an infant and the abuse of four other children at a Bear daycare facility. Dejoynay Ferguson, 20, is alleged to have suffocated a 4-month-old child to death and to have abused that child and four other children between July […]

Police seek information on suspect Prosecutors have secured the indictment of Justin Michael Chaffier in a February 2021 killing. Chaffier, 35, is charged with Murder First Degree and Stalking following a New Castle County police investigation into the murder of Nicole Crawford. “Nobody should ever have to know the pain that the Crawford family is […]

Attorney General Jennings today joined a nationwide investigation into Meta Platforms, Inc., formerly known as Facebook, for providing and promoting its social media platform – Instagram – to children and young adults despite knowing that such use is associated with physical and mental health harms. Attorneys General across the country are examining whether the company […]

Attorney General Kathleen Jennings announced today that the Delaware Department of Justice Consumer Protection Unit is investigating tech sales bootcamp Prehired and its CEO, Joshua Jordan. The investigation began in March, after Prehired filed nearly 300 debt-collection lawsuits in the Delaware Justice of the Peace Court seeking to enforce its income share agreements. Prehired started […]

Manila, Philippines — Former Philippine President Rodrigo Duterte said the International Criminal Court (ICC) should 'hurry up' with its probe of his war on drugs, remaining firm in his defense of the brutal campaign as he said the investigation should start immediately. "I'm asking the ICC to hurry up, and if possible, they can come here and start the investigation tomorrow," Duterte said in a congressional inquiry on his war on drugs. "If I am found guilty, I will go to prison." According to police data, more than 6,200 people died in anti-drug operations under Duterte's presidency, during which police typically said they had killed suspects in self-defense. Human rights groups believe the real toll to be far greater, with thousands more users and small-time peddlers killed in mysterious circumstances by unknown assailants. "I assume full responsibility for whatever happened in the actions taken by law enforcement agencies of this country to... stop the serious problem of drugs affecting our people," said Duterte, who served as president from 2016 to 2022. The ICC last year cleared the way for an investigation into the several thousand deaths and other suspected rights abuses. The Philippines withdrew from the ICC in March 2019. Appeals judges at the ICC subsequently ruled prosecutors still had jurisdiction over the alleged crimes because they occurred when the Philippines was an ICC member.

“While the investigation takes place, the town will refrain from any additional comment on this matter," according to a press release.

Exogenous substances, including drugs and chemicals, can transfer into human seminal fluid and influence male fertility and reproduction. In addition, substances relevant in the context of sports drug testing programs, can be transferred into the urine of a female athlete (after unprotected sexual intercourse) and trigger a so-called adverse analytical finding. Here, the question arises as to whether it is possible to distinguish analytically between intentional doping offenses and unintentional contamination of urine by seminal fluid. To this end, 480 seminal fluids from nonathletes were analyzed to identify concentration ranges and metabolite profiles of therapeutic drugs that are also classified as doping agents. Therefore, a screening procedure was developed using liquid chromatography connected to a triple quadrupole mass spectrometer, and suspect samples (i.e., samples indicating the presence of relevant compounds) were further subjected to liquid chromatography-high-resolution accurate mass (tandem) mass spectrometry. The screening method yielded 90 findings (including aromatase inhibitors, selective estrogen receptor modulators, diuretics, stimulants, glucocorticoids, beta-blockers, antidepressants, and the nonapproved proliferator-activated receptor delta agonist GW1516) in a total of 81 samples, with 91% of these suspected cases being verified by the confirmation method. In addition to the intact drug, phase-I and -II metabolites were also occasionally observed in the seminal fluid. This study demonstrated that various drugs including those categorized as doping agents partition into seminal fluid. Monitoring substances and metabolites may contribute to a better understanding of the distribution and metabolism of exogenous substances in seminal fluid that may be responsible for the impairment of male fertility.

The role of gastrin-releasing peptide receptor (GRPR) in various diseases, including cancer, has been extensively studied and has emerged as a promising therapeutic target. In this study, we successfully achieved the use of [²¹²Pb]Pb-DOTAM-GRPR1, comprising the α-particle generator, ²¹²Pb, combined with a GRPR-targeting peptide, GRPR1, in a prostate cancer model. Methods: Pharmacokinetics, toxicity, radiation dosimetry, and efficacy were assessed in GRPR-positive prostate tumor–bearing mice after intravenous administration of [²¹²Pb]Pb-DOTAM-GRPR1 (where DOTAM is 1,4,7,10-tetrakis(carbamoylmethyl)-1,4,7,10-tetraazacyclododecane). Results: Preclinical studies have shown tumor targeting of up to 5 percent injected dose per gram over 24 h, and optimization of the drug formulation and quantity has led to minimized oxidation and off-target binding, respectively. Particularly, an increase in peptide amount from 28 to 280 ng was shown to reduce off-target uptake, especially at the level of the pancreas, by about 30%. Furthermore, dosimetry studies confirmed the kidney as the dose-limiting organ, and toxicity studies revealed that a nontoxic dose of up to 1,665 kBq could be injected into mice. Efficacy studies indicated a median survival time of 9 wk in the control group, which received only a buffer solution, compared with 19 wk in the group that received 4 injections of 370 kBq at 3-wk intervals. Conclusion: Taken together, these combined data demonstrate the safety, tolerability, and efficacy of [²¹²Pb]Pb-DOTAM-GRPR1, thus warranting further exploration in clinical trials.

AI tools could help eliminate human bias in forensic investigations, say UCL scientists, who are using eye-tracking technology to study decision-making in skeletal analysis and crime scene examinations

The Competition Bureau has announced that it has expanded its investigation into Google’s online ad practices. This is the first major update to the investigation since it began in 2020, and a year later the competition watchdog obtained a court order from the Federal Courts of Appeal, requiring Google to produce records and written information […]

Greater Manchester Police launched a public appeal to help find Jane Burton on Tuesday morning but have paused the search after a body was found

An investigation into a Salmonella outbreak in Sweden has been restarted after more people fell sick. From August to October, 81 people from 18 regions contracted Salmonella Typhimurium with sequence type (ST) 36. Where information about the country of infection is available, all cases were infected in Sweden. Folkhälsomyndigheten (the Public... Continue Reading