fat American Kids Growing Fatter Than Their Canadian Cousins By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: American Kids Growing Fatter Than Their Canadian CousinsCategory: Health NewsCreated: 8/25/2015 12:00:00 AMLast Editorial Review: 8/26/2015 12:00:00 AM Full Article
fat Diet Study Suggests It's Carbs, Not Fats, That Are Bad for You By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Diet Study Suggests It's Carbs, Not Fats, That Are Bad for YouCategory: Health NewsCreated: 8/29/2017 12:00:00 AMLast Editorial Review: 8/30/2017 12:00:00 AM Full Article
fat Science Weighs in On How Fat Raises Cancer Risk By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Science Weighs in On How Fat Raises Cancer RiskCategory: Health NewsCreated: 9/1/2017 12:00:00 AMLast Editorial Review: 9/1/2017 12:00:00 AM Full Article
fat Later Breakfast, Earlier Dinner Might Help You Shed Body Fat By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Later Breakfast, Earlier Dinner Might Help You Shed Body FatCategory: Health NewsCreated: 8/30/2018 12:00:00 AMLast Editorial Review: 8/31/2018 12:00:00 AM Full Article
fat Caw-lesterol? Fatty City Food Hits Crows' Arteries By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Caw-lesterol? Fatty City Food Hits Crows' ArteriesCategory: Health NewsCreated: 8/26/2019 12:00:00 AMLast Editorial Review: 8/26/2019 12:00:00 AM Full Article
fat AHA News: Helping Fathers Connect With Their Kids, Involved Dad's Name Says It All By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: AHA News: Helping Fathers Connect With Their Kids, Involved Dad's Name Says It AllCategory: Health NewsCreated: 8/26/2020 12:00:00 AMLast Editorial Review: 8/27/2020 12:00:00 AM Full Article
fat Age Can Impair a Man's Odds for Fatherhood: Study By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Age Can Impair a Man's Odds for Fatherhood: StudyCategory: Health NewsCreated: 8/23/2021 12:00:00 AMLast Editorial Review: 8/23/2021 12:00:00 AM Full Article
fat Pandemic Tied to Rising Number of Fatal Opioid ODs By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Pandemic Tied to Rising Number of Fatal Opioid ODsCategory: Health NewsCreated: 8/24/2021 12:00:00 AMLast Editorial Review: 8/24/2021 12:00:00 AM Full Article
fat Fatal ODs From Illicit Tranquilizers Jumped 6-Fold During Pandemic By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Fatal ODs From Illicit Tranquilizers Jumped 6-Fold During PandemicCategory: Health NewsCreated: 8/26/2021 12:00:00 AMLast Editorial Review: 8/27/2021 12:00:00 AM Full Article
fat The effect of graded exercise therapy on fatigue in people with serious respiratory illness: a systematic review By err.ersjournals.com Published On :: 2024-10-09T00:15:15-07:00 Background In adults with serious respiratory illness, fatigue is prevalent and under-recognised, with few treatment options. The aim of this review was to assess the impact of graded exercise therapy (GET) on fatigue in adults with serious respiratory illness. Methods Electronic databases were searched to identify randomised controlled trials (RCTs) testing GET (involving incremental increases in exercise from an established baseline) in adults with serious respiratory illness. The primary outcome was fatigue and secondary outcomes were health-related quality of life (HRQoL) and adverse events. Two authors independently screened for inclusion, evaluated risk of bias and extracted data. Results 76 RCTs were included with 3309 participants, most with a diagnosis of COPD or asthma. Reductions in fatigue measured by the Chronic Respiratory Disease Questionnaire fatigue domain score were demonstrated following GET consisting of aerobic with/without resistance training (mean difference (MD) 0.53 points, 95% CI 0.41–0.65, 11 RCTs, 624 participants) and GET using resistance training alone (MD 0.58 points, 95% CI 0.21–0.96, two RCTs, 82 participants) compared with usual care. Although the mean effect exceeded the minimal important difference, the lower end of the confidence intervals did not always exceed this threshold so the clinical significance could not be confirmed. GET consistently improved HRQoL in people with a range of chronic respiratory diseases on multiple HRQoL measures. No serious adverse events related to GET were reported. Conclusion GET may improve fatigue alongside consistent improvements in HRQoL in people with serious respiratory illness. These findings support the use of GET in the care of people with serious respiratory illness. Full Article
fat Potential Drawbacks of Noninvasive Diagnostic Methods for Nonalcoholic Fatty Liver Disease By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 The rising obesity epidemic is a phenomenon that has gained increasing attention from health providers and health policy makers. This led to recognition of nonalcoholic fatty liver disease (MASLD). The standard for its assessment has been histologic, which is neither practical nor acceptable by patients. Subsequently, a number of noninvasive assessment methods have been developed. However, despite ease of implementation, their confounding variables do hinder their accuracy. Nonetheless, the development of the liver stiffness measurement (LSM) and incorporation of other biological parameters has minimized but not eliminated the need for liver biopsy. Imaging methods are useful in evaluation, estimation, and following the progression of steatosis and fibrosis with particular attention to controlled attenuation parameter (CAP) and MRI–Proton Density Fat Fraction (MRI-PDFF). The choices for the family physician are broad and rely on tests’ availability, cost, and patient acceptance. Great efforts have been undertaken to produce more robust and novel noninvasive markers that indicate fibrinogenesis directly in an implementable and cost-effective way. Full Article
fat The Simultaneous Inhibition of Solute Carrier Family 6 Member 19 and Breast Cancer Resistance Protein Transporters Leads to an Increase of Indoxyl Sulfate (a Uremic Toxin) in Plasma and Kidney [Articles] By dmd.aspetjournals.org Published On :: 2024-10-16T09:02:03-07:00 Solute carrier family 6 member 19 (SLC6A19) inhibitors are being studied as therapeutic agents for phenylketonuria. In this work, a potent SLC6A19 inhibitor (RA836) elevated rat kidney uremic toxin indoxyl sulfate (IDS) levels by intensity (arbitrary unit) of 13.7 ± 7.7 compared with vehicle 0.3 ± 0.1 (P = 0.01) as determined by tissue mass spectrometry imaging analysis. We hypothesized that increased plasma and kidney levels of IDS could be caused by the simultaneous inhibition of both Slc6a19 and a kidney IDS transporter responsible for excretion of IDS into urine. To test this, we first confirmed the formation of IDS through tryptophan metabolism by feeding rats a Trp-free diet. Inhibiting Slc6a19 with RA836 led to increased IDS in these rats. Next, RA836 and its key metabolites were evaluated in vitro for inhibiting kidney transporters such as organic anion transporter (OAT)1, OAT3, and breast cancer resistance protein (BCRP). RA836 inhibits BCRP with an IC50 of 0.045 μM but shows no significant inhibition of OAT1 or OAT3. Finally, RA836 analogs with either potent or no inhibition of SLC6A19 and/or BCRP were synthesized and administered to rats fed a normal diet. Plasma and kidney samples were collected to quantify IDS using liquid chromatography–mass spectrometry. Neither a SLC6A19 inactive but potent BCRP inhibitor nor a SLC6A19 active but weak BCRP inhibitor raised IDS levels, whereas compounds inhibiting both transporters caused IDS accumulation in rat plasma and kidney, supporting the hypothesis that rat Bcrp contributes to the excretion of IDS. In summary, we identified that inhibiting Slc6a19 increases IDS formation, while simultaneously inhibiting Bcrp results in IDS accumulation in the kidney and plasma. SIGNIFICANCE STATEMENT This is the first publication to decipher the mechanism for accumulation of indoxyl sulfate (IDS) (a uremic toxin) in rats via inhibition of both Slc6a19 and Bcrp. Specifically, inhibition of Slc6a19 in the gastrointestinal track increases IDS formation, and inhibition of Bcrp in the kidney blocks IDS excretion. Therefore, we should avoid inhibiting both solute carrier family 6 member 19 and breast cancer resistance protein simultaneously in humans to prevent accumulation of IDS, a known risk factor for cardiovascular disease, psychic anxiety, and mortality in chronic kidney disease patients. Full Article
fat Proteomic Analysis of Signaling Pathways Modulated by Fatty Acid Binding Protein 5 (FABP5) in Macrophages [Special Section: Cannabinoid Signaling in Human Health and Disease] By jpet.aspetjournals.org Published On :: 2024-10-18T07:04:15-07:00 Although acute inflammation serves essential functions in maintaining tissue homeostasis, chronic inflammation is causally linked to many diseases. Macrophages are a major cell type that orchestrates inflammatory processes. During inflammation, macrophages undergo polarization and activation, thereby mobilizing pro-inflammatory and anti-inflammatory transcriptional programs that regulate ensuing macrophage functions. Fatty acid binding protein 5 (FABP5) is a lipid chaperone highly expressed in macrophages. FABP5 deletion is implicated in driving macrophages toward an anti-inflammatory phenotype, yet signaling pathways regulated by macrophage-FABP5 have not been systematically profiled. We leveraged proteomic and phosphoproteomic approaches to characterize pathways modulated by FABP5 in M1 and M2 polarized bone marrow-derived macrophages (BMDMs). Stable isotope labeling by amino acids-based analysis of M1 and M2 polarized wild-type and FABP5 knockout BMDMs revealed numerous differentially regulated proteins and phosphoproteins. FABP5 deletion impacted downstream pathways associated with inflammation, cytokine production, oxidative stress, and kinase activity. Toll-like receptor 2 (TLR2) emerged as a novel target of FABP5 and pharmacological FABP5 inhibition blunted TLR2-mediated activation of downstream pathways, ascribing a novel role for FABP5 in TLR2 signaling. This study represents a comprehensive characterization of the impact of FABP5 deletion on the proteomic and phosphoproteomic landscape of M1 and M2 polarized BMDMs. Loss of FABP5 altered pathways implicated in inflammatory responses, macrophage function, and TLR2 signaling. This work provides a foundation for future studies seeking to investigate the therapeutic potential of FABP5 inhibition in pathophysiological states resulting from dysregulated inflammatory signaling. SIGNIFICANCE STATEMENT This research offers a comprehensive analysis of fatty acid binding protein 5 (FABP5) in macrophages during inflammatory response. The authors employed quantitative proteomic and phosphoproteomic approaches to investigate this utilizing bone marrow-derived macrophages that were M1 and M2 polarized using lipopolysaccharide with interferon and interleukin-4, respectively. This revealed multiple pathways related to inflammation that were differentially regulated due to the absence of FABP5. These findings underscore the potential therapeutic significance of macrophage-FABP5 as a candidate for addressing inflammatory-related diseases. Full Article
fat Prevalence of Rathke Cleft and Other Incidental Pituitary Gland Findings on Contrast-Enhanced 3D Fat-Saturated T1 MPRAGE at 7T MRI [CLINICAL PRACTICE] By www.ajnr.org Published On :: 2024-11-07T15:14:12-08:00 BACKGROUND AND PURPOSE: A cleftlike nonenhancing hypointensity was observed repeatedly in the pituitary gland at the adenohypophysis/neurohypophysis border on contrast-enhanced 3D fat-saturated T1-MPRAGE using clinical 7T MRI. Our primary goal was to assess the prevalence of this finding. The secondary goals were to evaluate the frequency of other incidental pituitary lesions, MRI artifacts, and their effect on pituitary imaging on the contrast-enhanced 3D fat-saturated T1 MPRAGE at 7T. MATERIALS AND METHODS: One hundred patients who underwent 7T neuroimaging between October 27, 2021, and August 10, 2023, were included. Each case was evaluated for cleftlike pituitary hypointensity, pituitary masses, and artifacts on contrast-enhanced 3D fat-saturated T1 MPRAGE. Follow-up examinations were evaluated if present. The average prevalence for each finding was calculated, as were descriptive statistics for age and sex. RESULTS: A cleftlike hypointensity was present in 66% of 7T MRIs. There were no significant differences between the "cleftlike present" and "cleftlike absent" groups regarding sex (P = .39) and age (P = .32). The cleftlike hypointensity was demonstrated on follow-up MRIs in 3/3 patients with 7T, 1/12 with 3T, and 1/5 with 1.5T. A mass was found in 22%, while 75% had no mass and 3% were indeterminate. A mass was found in 18 (27%) of the cleftlike present and 4 (13%) of the cleftlike absent groups. The most common mass types were Rathke cleft cyst in 7 (31.8%) patients, "Rathke cleft cyst versus entrapped CSF" in 6 (27.3%), and microadenoma in 6 (22.2%) in the cleftlike present group. There were no significant differences in the mass types between the cleftlike present and cleftlike absent groups (P = .23). Susceptibility and/or motion artifacts were frequent using contrast-enhanced 3D fat-saturated T1 MPRAGE (54%). Artifact-free scans were significantly more frequent in the cleftlike present group (P = .03). CONCLUSIONS: A cleftlike nonenhancing hypointensity was frequently seen on the contrast-enhanced 3D fat-saturated T1 MPRAGE images at 7T MRI, which most likely represents a normal embryologic Rathke cleft remnant and cannot be seen in lower-field-strength MRIs. Susceptibility and motion artifacts are common in the sella. They may affect image quality, and the artifacts at 7T may lead to an underestimation of the prevalence of the Rathke cleft and other incidental findings. Full Article
fat Pericarotid Fat as a Marker of Cerebrovascular Risk [RESEARCH] By www.ajnr.org Published On :: 2024-11-07T15:14:12-08:00 SUMMARY: Vascular inflammation is widely recognized as an important factor in the atherosclerotic process, particularly in terms of plaque development and progression. Conventional tests, such as measuring circulating inflammatory biomarkers, lack the precision to identify specific areas of vascular inflammation. In this context, noninvasive imaging modalities can detect perivascular fat changes, serving as a marker of vascular inflammation. This review aims to provide a comprehensive overview of the key concepts related to perivascular carotid fat and its pathophysiology. Additionally, we examine the existing literature on the association of pericarotid fat with features of plaque vulnerability and cerebrovascular events. Finally, we scrutinize the advantages and limitations of the noninvasive assessment of pericarotid fat. Full Article
fat San Antonio truck driver pleads guilty in fatal human smuggling case By www.pbs.org Published On :: Tue, 17 Oct 2017 14:44:25 +0000 Police officers work on a crime scene after 10 undocumented immigrants being smuggled into the U.S. were found dead inside a sweltering 18-wheeler trailer parked behind a Walmart store in San Antonio. Photo by Ray Whitehouse/Reuters A 61-year-old San Antonio man pleaded guilty to two federal charges in the human smuggling incident that led to the deaths of 10 undocumented immigrants this summer. James Matthew Bradley Jr., who appeared before a U.S. magistrate judge Monday, pleaded guilty to “one count of conspiracy to transport aliens resulting in death and one count of transporting aliens resulting in death,” according to a statement from the U.S. Attorney’s Office for the Western District of Texas. The office added that Bradley’s “admission of guilt” meant he packed dozens of unauthorized immigrants into a tractor-trailer for financial gain, adding that the suspect confirmed that details from court documents were “factually correct.” On July 23, San Antonio Police Department officers responded to a call from a Walmart employee shortly past midnight. Once officers arrived, they found 39 immigrants at the scene. Of those carried in the tractor-trailer, eight were found dead in the rear of the trailer, while two died later at nearby hospitals, the statement said. Survivors of the incident said there was no air conditioning in the overheated trailer and had to take turns to breath through a hole in the back of the truck for air. Bradley also initially told investigators that he was unaware of the immigrants in the trailer until he had stopped at the Walmart in San Antonio for bathroom break. The attorney’s office also said Bradley faces up to life in prison with the charges and that he is scheduled to be sentenced in January 2018. Immigrants said there were up to 200 people transported on the trailer and that different fees were quoted to them for the ride north from the U.S.-Mexico border, the statement added. Jason Buch of San Antonio Express-News told the NewsHour earlier this year that Border Patrol agents in Laredo, Texas, reported an uptick of immigrants using tractor-trailers to get pass checkpoints at the border. “People are usually going on to major metropolitan areas or regions of the country that employ a lot of immigrant laborers, so, areas with large agriculture industries or construction booms,” Buch said. The NewsHour’s John Yang learned more about the July human smuggling case and immigration politics from Jason Buch of San Antonio Express News. Shane M. Folden, special agent in charge of homeland security investigations in San Antonio, said in the statement that the proceeding “helps to close the door on one of the conspirators responsible for causing the tragic loss of life and wreaking havoc on those who survived this horrific incident.” “This case is a glaring reminder that alien smugglers are driven by greed and have little regard for the health and well-being of their human cargo, which can prove to be a deadly combination,” he added. Bradley’s co-defendant Pedro Silva Segura was also indicted last month with faces two counts of conspiracy and two counts of transporting undocumented immigrants resulting in serious bodily injury and placing lives in jeopardy. Segura, 47, is an undocumented immigrant who resides in Laredo, Texas. The post San Antonio truck driver pleads guilty in fatal human smuggling case appeared first on PBS NewsHour. Full Article human smuggling immigration James Matthew Bradley Jr. San Antonio texas
fat Planet in the 'forbidden zone' of dead star could reveal Earth's fate By www.newscientist.com Published On :: Thu, 26 Sep 2024 11:00:57 +0100 A distant planet should have been consumed when its star expanded to become a red giant, perhaps offering insights into planetary migration Full Article
fat What We Do in the Shadows Recap: Like Father, Like Son By www.vulture.com Published On :: Wed, 13 Nov 2024 00:41:30 GMT Ghost dads are so embarrassing. Full Article tv tv recaps overnights recaps what we do in the shadows what we do in the shadows season 6 fx comedy
fat Father and son team die at Isle of Man TT to take death total to five By www.telegraph.co.uk Published On :: Fri, 10 Jun 2022 17:49:10 GMT Full Article topics:places/isle-of-man structure:sport storytype:standard
fat Chronic fatigue syndrome could be quickly diagnosed via a blood test By www.newscientist.com Published On :: Mon, 09 Sep 2024 17:19:21 +0100 Levels of certain cells, fatty molecules and proteins in the blood are different in people with chronic fatigue syndrome than in those without it, which could help doctors spot the condition sooner Full Article
fat The Chonky Superstar of Fat Bear Week Is Missing, and the Competition Won't Be the Same Without Him By www.smithsonianmag.com Published On :: Thu, 03 Oct 2024 12:00:00 +0000 While other bears battled over fish in a prime spot, Otis would sit off to the side and wait for the fish to come to him. But so far this year, he hasn’t been spotted in Katmai National Park and Preserve Full Article
fat The Tears of Unfathomable Sadness: SNL Cast Member Admits That Elon Musk Made Her Cry By twitchy.com Published On :: Tue, 12 Nov 2024 15:30:00 -0500 Full Article <![CDATA[crying]]> <![CDATA[Elon Musk]]> <![CDATA[saturday night live]]> <![CDATA[SNL]]>
fat Apple Arcade Weekly Round-Up: New Content and Feature Updates Are Now Live for TMNT Splintered Fate, Temple Run: Legends, Vampire Survivors, Simon’s Cat, and More By toucharcade.com Published On :: Thu, 22 Aug 2024 08:09:15 +0000 Following yesterday’s big Disney Dreamlight Valley update on Apple Arcade and other platforms, a few more notable games on Apple’s … Continue reading "Apple Arcade Weekly Round-Up: New Content and Feature Updates Are Now Live for TMNT Splintered Fate, Temple Run: Legends, Vampire Survivors, Simon’s Cat, and More" Full Article Apple Arcade Featured Games iPad Games iPhone games News Universal
fat Best iPhone Game Updates: ‘TMNT Splintered Fate’, ‘Subway Surfers’, ‘Another Eden’, and More By toucharcade.com Published On :: Mon, 26 Aug 2024 22:00:04 +0000 Hello everyone, and welcome to the week! It’s time once again for our look back at the noteworthy updates of … Continue reading "Best iPhone Game Updates: ‘TMNT Splintered Fate’, ‘Subway Surfers’, ‘Another Eden’, and More" Full Article Featured Games iPad Games iPhone games News Updates
fat The Best Switch Visual Novels and Adventure Games in 2024 – From Fata Morgana and VA-11 Hall-A to Famicom Detective Club and Gnosia By toucharcade.com Published On :: Wed, 04 Sep 2024 23:38:08 +0000 After tackling the best party games on Switch in 2024, the recent release of Emio – The Smiling Man: Famicom … Continue reading "The Best Switch Visual Novels and Adventure Games in 2024 – From Fata Morgana and VA-11 Hall-A to Famicom Detective Club and Gnosia" Full Article Featured News SwitchArcade
fat DFAT makes room for women By www.theaustralian.com.au Published On :: Wed, 11 Jan 2017 13:00:00 GMT The Department of Foreign Affairs and Trade has renamed its meeting rooms in honour of pioneering female diplomats. Full Article
fat 236332: US saw "additional opportunities" to embed own troops in Pakistan military’s FATA operations By www.thehindu.com Published On :: Sat, 21 May 2011 02:26:52 +0530 Full Article The Cables
fat Get Ready to #PutSomeWindexOnIt - Windex� Brand and My Big Fat Greek Wedding 2 By www.multivu.com Published On :: 18 Mar 2016 10:45:00 EDT Windex� Brand celebrates the upcoming launch of My Big Fat Greek Wedding 2 Full Article Advertising Film & Motion picture Household Consumer Cosmetics Retail Household Products (vacuum cleaners supplies etc) Social Media Broadcast Feed Announcements MultiVu Video
fat New PSAs Released as Part of Ad Council and AARP Caregiver Assistance Campaign Supported by NAB, RAB, and OAAA This Mother's and Father's Day - PERSPECTIVES :30 By www.multivu.com Published On :: 05 May 2015 15:20:00 EDT PERSPECTIVES :30 Full Article Advertising Healthcare Hospitals Broadcast Feed Announcements Senior Citizens MultiVu Video
fat As Fat Grafting Evolves, Aesthetic Plastic Surgeons Discover That Less Can Be More, It's Not Just For The Breasts And Buttocks, And Fat Doesn't Always Act Like Fat - Body Contouring with Fat, AKA Liquid Gold By www.multivu.com Published On :: 18 May 2015 20:35:00 EDT Video 1 Preview Image Caption Full Article Healthcare Hospitals Medical Pharmaceuticals Broadcast Feed Announcements MultiVu Video
fat Colgate Total� Teams Up with the American Diabetes Association� and Funnyman Joey Fatone to Bring "30 Days of Laughter" to the Diabetes Community - Joey Fatone: IN SINK By www.multivu.com Published On :: 12 Nov 2015 10:37:00 EST Joey Fatone: IN SINK Full Article Entertainment Healthcare Hospitals Household Consumer Cosmetics Retail Dentistry Broadcast Feed Announcements MultiVu Video
fat Fatima Bhutto: Kamala Harris's Support for Israel's Genocide in Gaza Is a Betrayal of True Feminism By www.democracynow.org Published On :: Thu, 07 Nov 2024 08:34:25 -0500 With former U.S. President Donald Trump returning to the White House for a second term, we speak with Pakistani author and columnist Fatima Bhutto. Bhutto is an award-winning author and writes a monthly column for Zeteo on world affairs. She criticizes Kamala Harris’s campaign for relying heavily on celebrity endorsements and vague appeals to “joy” while silencing dissent on Gaza as the Biden administration continues backing Israel. “You don’t need to be a man to practice toxic masculinity, and you don’t need to be white to practice white supremacy,” says Bhutto. Full Article
fat People with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome May Have an "Exhausted" Immune System By www.scientificamerican.com Published On :: Wed, 21 Feb 2024 19:15:00 GMT A long-awaited study of people with ME/CFS revealed differences in their immune and nervous system. The findings may offer clues about long COVID Full Article Health Epidemiology Medicine Mind & Brain
fat 25 Pawsitive Energy Meowtivation Memes of Fierce Felines for Fending off Fall Fatigue By cheezburger.com Published On :: Sat, 09 Nov 2024 14:00:00 -0800 Unfortunately, life offers a myriad of buzzkillers throughout the day. Sometimes they pounce on you with some alarming news, but most of the time they creep in, luring you to slouch on the couch like snoozy sirens, and you can't find the will to fight back. It can be the cold weather, a grouchy boss, or even current events - negative thoughts and low energy tend to spread like a bad odor. Well, that's just not going to happen, fellow I Can Has-ers! We got your back. All you need is an energy boost of fierce feline funnies, furrociously pumping their paws. True, there are plenty of meownching photos in our content menu. We don't deny it! For everything, there is a season, a time to munch, and a time to crunch. For days of gloomy clouds, boring work, or just when your boss doesn't get your priorities (cats first, obviously), our Paw Power Practice is just the thing for you. The method we developed is both refreshing AND as old as time: the secret is to laugh until your abs strengthen, and your frown is upside down. Feline Fitness Fun, Try it! Fending off fall fatigue has never been so easy. Full Article funny cat memes motivation feline funnies gym workout mood booster fitness funny memes Memes cat memes
fat 22 Fatigued Feline Memes Taking a 16-Hour Nap Nocturnating During the Day. And Night. And the Day After. By cheezburger.com Published On :: Tue, 12 Nov 2024 13:00:00 -0800 Cats can sleep for eternity, and somehow still be tired. Sleep surrounds cats, probably because they're such cutie patooties when they sleep. It's like the universe graces us, humble hoomans, with the gift of watching cats sleep - and it gives it to us in abundance. Sleepy cats are among the cutest things the world can offer us, and we cannot be more grateful for the eep that cats have. It's a true internal struggle - the urge to schmoop them and pet them because cats are absolutely pawdorable when they sleep - but with the realization that we can't, because it will disturb their precious princely sleep.Since we cannot disturb the cats with the big eep who sleep, we prepared a bunch of sleepy cat memes to scroll through, so we can deal with the pet urge together, all cat pawrents. Gather the strength and don't fall asleep - it's worth it. Full Article sleep memes hilarious Memes hilarious memes sleep Cats hilarious cats sleeping sleepy cat memes
fat anyone can be a father By www.toothpastefordinner.com Published On :: Mon, 27 Mar 2023 05:00:00 EDT Today on Toothpaste For Dinner: anyone can be a fatherThis RSS feed is brought to you by Drew and Natalie's podcast Garbage Brain University. Our new series Everything Is Real explores the world of cryptids, aliens, quantum physics, the occult, and more. If you use this RSS feed, please consider supporting us by becoming a patron. Patronage includes membership to our private Discord server and other bonus material non-patrons never see! Full Article comic
fat Stepsisters hide 18-year-old's passport so she would miss the family vacation and take care of the kids, father retaliates by cancelling the whole trip: 'I was livid' By cheezburger.com Published On :: Tue, 12 Nov 2024 11:00:00 -0800 There is a lot of irresponsible parenting in this story. First, let's start with the stepsisters in question. This is a pair of 25 and 28-year-old single moms who were so reliant on the Redditor's 18-year-old daughter to babysit their kids that they couldn't possibly get a real babysitter to take care of them. So when it came time for a family vacation, the stepsisters tried to convince the Redditor's daughter to stay behind, despite the fact that she wanted to partake in some much-deserved time off as well.Then, there's the Redditor's wife, who tried to defend her fully-grown daughters for trying to sabotage the 18-year-old's ability to join the family on the trip. These ladies stole her passport, leaving the 18-year-old and her father scrambling just hours before their flight departure. Tension was so high between all the members of the family that the Redditor decided to cancel the entire trip. Looks like his stepdaughters would have to take care of their own kids for a change.Keep scrolling below for the full story and for the best reactions from folks in the comments section. For more, check out this post about a Thanksgiving meltdown. Full Article family drama aita stepsisters family stepdad reddit thread Reddit Father
fat Don’t let small town values decide the fate of women By freethoughtblogs.com Published On :: Sun, 03 Nov 2024 21:34:18 +0000 Republicans seem to be proud of their ‘solution’ for abortion: they’ll just devolve everything to the states and local authorities, so they don’t have their callousness and brutality thrown into their faces on the national level anymore. As far as I’m concerned, this is the worst possible solution. It puts women under the thumb of […] Full Article Abortion
fat Jury shown video of father slapping Sara Sharif By www.bbc.com Published On :: Tue, 12 Nov 2024 16:59:48 GMT The home video was filmed less than 13 months before Sara was found dead with multiple injuries. Full Article
fat How a High-Fat Diet Impacts Your Brain and Body? By www.medindia.net Published On :: Research suggests that while a high-fat diet raises the risk of diabetes and obesity, it might not be the sole factor causing changes in the brain. Full Article
fat Curb High-Fat Dairy to Lower Fatty Liver Disease Risk By www.medindia.net Published On :: Reducing high-fat dairy intake may help lower the risk of developing fatty liver disease, offering a simple dietary step for better liver health. Full Article
fat Forced Fatherhood - Men's Rights Differ Regarding Parenthood By www.medindia.net Published On :: The inconsistencies in the law regarding the rights of men in claiming parenthood with frozen embryos and developing embryo situations in pregnancies Full Article
fat Supreme Court of India rules on Condition of Persons Suffering from Chronic Fatigue Syndrome By www.medindia.net Published On :: b Highlights:/b ul class="group-list punch-points" li The petition arose from the denial of diagnosing the treatment of CFS./li li Diagnosis, Full Article
fat Fat Metabolism Inhibits Regeneration in Central Nervous System By www.medindia.net Published On :: Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system in which the immune system attacks the protective sheath myelin that covers the nerve fibers. Full Article
fat Enzyme That 'Loads Up' Fat-Carrying Particles Found Out By www.medindia.net Published On :: A new enzyme that loads up fat-carrying particles in the liver before transporting it to different parts of the body has been discovered by the researchers. Full Article
fat Blood Fats Predict the Onset of Diabetes and Cardiovascular Disease By www.medindia.net Published On :: Measuring various types of fats in the blood ("lipidomics") can predict the risk of developing type 2 diabetes (T2D) and cardiovascular disease (CVD) Full Article
fat Indians Predisposed to Insulin Resistance More Prone to Fatty Liver Disease By www.medindia.net Published On :: Being highly predisposed to insulin resistance puts Indians at a higher risk of developing non-alcoholic fatty liver disease (NAFLD), suggest health experts. Full Article
fat Health Ministry Launches New Guidelines for Non-Alcoholic Fatty Liver Disease By www.medindia.net Published On :: The Union Health Ministry released revised operational guidelines and a training module aimed at enhancing care for individuals with bNon-Alcoholic Fatty Liver Disease (NAFLD)/b. Full Article
fat Inhalation of Hydrogen-Rich Gas Reduces Exercise Fatigue By www.medindia.net Published On :: A recent study featured in the iInternational Journal of Sports Medicine/i titled "Inhalation of Hydrogen-Rich Gas Before Acute Exercise Alleviates Full Article
fat South Korean Workplace Culture Shifts as Fathers Embrace Childcare By www.medindia.net Published On :: South Korean men made up one-third of all medlinkchildcare/medlink leave takers in the first half of this year, marking a historic milestone as their Full Article
