Let’s try and get you up to speed on the fascinating oddity that is simulation game Ecosystem, on the off chance that Nate's coverage of it hasn't stuck with you like an unwelcome brain parasite you’re nonetheless unwilling to get removed for fear of the lingering emptiness it might cause (he once described an eel as “a quaver with erectile dysfunction”). Broadly speaking, this game is Spore’s evolutionary-biology-degree-having cousin. It’s been in early access for about three years now, but with the latest "Crustacean" update, it’s just hit 1.0. Once again, carcinization has come for all things.

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In the centre of a distant galaxy, a supermassive black hole has swallowed up a star 9 times the sun’s mass in the biggest and brightest such cosmic meal we’ve ever seen

Spanning 23 million light years, or 220 Milky Way galaxies, a set of giant, newly discovered black hole jets known as Porphyrion may change our understanding of black holes and the structure of the universe

The Biden administration passed $3 trillion of legislation aimed at revitalizing the American economy and fostering green, equitable, "middle-out" growth.

Geraint Thomas wins bronze after crash proves costly in men's time trial

It is official - England is the world's heptathlon talent factory

Eilish McColgan follows mother's footsteps with thrilling gold medal run at Commonwealth Games

Anna Henderson wins silver in women's time trial

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Estimates on the cost of foodborne illness in Australia have revealed poultry is associated with the highest burden. In 2023, Food Standards Australia New Zealand (FSANZ) commissioned the University of Melbourne and the Australian National University to estimate the annual cost of foodborne illness caused by food commodities and pathogens.... Continue Reading

I’ve been hearing a lot about IPTV lately. There’s no denying that it’s shaken up the way we consume content. From streaming live sports events to watching your favorite shows on demand, IPTV services have become incredibly popular. But let’s be honest: with so many different subscription options out there, it can get a little […]

The post Is a Premium IPTV Subscription Worth the Extra Cost? appeared first on Chart Attack.

As a truck owner who’s watching every penny, you know how quickly maintenance expenses can get out of hand. There’s always another issue, another part to replace, another tool you didn’t know you needed. But there’s good news – plenty of ways exist to keep those trucks running smoothly without draining your wallet. With a […]

The post Maintenance Tips for Budget-Conscious Truck Owners ─ Keeping Costs Down appeared first on Chart Attack.

Speculator swapped pricey domain for OpenAI shares instead of taking cash payment.

Significant visual and comfort compromises make last year's Quest 3 a better VR investment.

Among Us (Free) has done loads of crossovers and collaborations over the years, but one I didn’t expect at all …

Continue reading "‘Among Us’ Is Collaborating With ‘Ace Attorney Investigations’ for Its Newest Free Cosmetic DLC Out Next Week"

A dome-shaped device floating in Halifax’s Northwest Arm could easily be confused with a buoy, but it is actually a contraption meant to turn ocean water into fresh water. Two Dalhousie University researchers hope it can help with water scarcity in the real world.

Via Rail's service standards have eroded substantially over the last decade, with many more trains arriving late.

The UK could face a £22bn hit to its exports if Donald Trump carries out his tariff threats, researchers say.

New research suggests the ­majority of businesses expect to be hit with energy price rises again this year.

A Muslim bigamist will have his court costs paid by the federal government.

An Iftar dinner party thrown by the PM and attended by a controversial Islamic preacher cost taxpayers more than $30,000.

The Federation of Pharmaceutical Entrepreneurs (FOPE) has identified potential opportunities for Indian pharmaceutical companies to expand in Australia. Further, the India─Australia Economic Cooperation and Trade

Indian pharma and biotech companies are confident that under the new US President Donald Trump, its strengths in high quality generics manufacture and export will continue to command respect. This view is

This week, I’m rerunning some popular posts while we put the finishing touches on DCI’s new 2024-25 Economic Report on Pharmaceutical Wholesalers and Specialty Distributors.

The article below highlights an underappreciated consequence of the Inflation Reduction Act’s inflation rebates for Medicare Part B drugs. Last night, I posted an updated analysis showing that the volatility in seniors' coinsurance rates continues. For the fourther quarter of 2024, coinsurance rates for 51 drugs increased, while rates for only 19 drugs decreased. What's more, rates for 17 drugs returned to their original 20% level. Click here to see our original post from May 2024.

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Contrary to what you may have heard, the Inflation Reduction Act’s (IRA) inflation rebates for Medicare Part B drugs do not always save money for seniors.

As we document below, a growing share of Part B drugs have inflation-adjusted coinsurance rates that have been increasing, not declining. In many cases, the coinsurance rate declines only briefly before rebounding back to the standard 20% rate. What’s more, these fluctuations have triggered huge jumps in patients’ out-of-pocket obligations for some drugs—even when a drug’s costs were falling.

Chalk off these coinsurance surprises to yet another unintended consequence of the IRA. Seniors who are expecting to see costs drop may find they are instead being taken for a rollercoaster ride.
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Community pharmacies should be reimbursed for their additional costs during the COVID-19 pandemic “as soon as possible”, the prime minister has told The Pharmaceutical Journal.

For people with diabetes, glucose monitors are a valuable tool to monitor their blood sugar. The current generation of these biosensors detect glucose levels with thin, metallic filaments inserted in subcutaneous tissue, the deepest layer of the skin where most body fat is stored.

Medical technology company Biolinq is developing a new type of glucose sensor that doesn’t go deeper than the dermis, the middle layer of skin that sits above the subcutaneous tissue. The company’s “intradermal” biosensors take advantage of metabolic activity in shallower layers of skin, using an array of electrochemical microsensors to measure glucose—and other chemicals in the body—just beneath the skin’s surface.

Biolinq just concluded a pivotal clinical trial earlier this month, according to CEO Rich Yang, and the company plans to submit the device to the U.S. Food and Drug Administration for approval at the end of the year. In April, Biolinq received US $58 million in funding to support the completion of its clinical trials and subsequent submission to the FDA.

Biolinq’s glucose sensor is “the world’s first intradermal sensor that is completely autonomous,” Yang says. While other glucose monitors require a smartphone or other reader to collect and display the data, Biolinq’s includes an LED display to show when the user’s glucose is within a healthy range (indicated by a blue light) or above that range (yellow light). “We’re providing real-time feedback for people who otherwise could not see or feel their symptoms,” Yang says. (In addition to this real-time feedback, the user can also load long-term data onto a smartphone by placing it next to the sensor, like Abbott’s FreeStyle Libre, another glucose monitor.)

More than 2,000 microsensor components are etched onto each 200-millimeter silicon wafer used to manufacture the biosensors.Biolinq

Biolinq’s hope is that its approach could lead to sustainable changes in behavior on the part of the individual using the sensor. The device is intentionally placed on the upper forearm to be in plain sight, so users can receive immediate feedback without manually checking a reader. “If you drink a glass of orange juice or soda, you’ll see this go from blue to yellow,” Yang explains. That could help users better understand how their actions—such as drinking a sugary beverage—change their blood sugar and take steps to reduce that effect.

Biolinq’s device consists of an array of microneedles etched onto a silicon wafer using semiconductor manufacturing. (Other glucose sensors’ filaments are inserted with an introducer needle.) Each chip has a small 2-millimeter by 2-millimeter footprint and contains seven independent microneedles, which are coated with membranes through a process similar to electroplating in jewelry making. One challenge the industry has faced is ensuring that microsensors do not break at this small scale. The key engineering insight Biolinq introduced, Yang says, was using semiconductor manufacturing to build the biosensors. Importantly, he says, silicon “is harder than titanium and steel at this scale.”

Miniaturization allows for sensing closer to the surface of the skin, where there is a high level of metabolic activity. That makes the shallow depth ideal for monitoring glucose, as well as other important biomarkers, Yang says. Due to this versatility, combined with the use of a sensor array, the device in development can also monitor lactate, an important indicator of muscle fatigue. With the addition of a third data point, ketones (which are produced when the body burns fat), Biolinq aims to “essentially have a metabolic panel on one chip,” Yang says.

Using an array of sensors also creates redundancy, improving the reliability of the device if one sensor fails or becomes less accurate. Glucose monitors tend to drift over the course of wear, but with multiple sensors, Yang says that drift can be better managed.

One downside to the autonomous display is the drain on battery life, Yang says. The battery life limits the biosensor’s wear time to 5 days in the first-generation device. Biolinq aims to extend that to 10 days of continuous wear in its second generation, which is currently in development, by using a custom chip optimized for low-power consumption rather than off-the-shelf components.

The company has collected nearly 1 million hours of human performance data, along with comparators including commercial glucose monitors and venous blood samples, Yang says. Biolinq aims to gain FDA approval first for use in people with type 2 diabetes not using insulin and later expand to other medical indications.

This article appears in the August 2024 print issue as “Glucose Monitor Takes Page From Chipmaking.”

Jun 26, 2024

Air-source heat pump adoption will increase heating costs for approximately half of all Massachusetts households due to high electricity prices, according to a new town-level spatial analysis by researchers at Harvard University. Concerns around increased energy bills could challenge Massachusetts’ ability to achieve its ambitions for decarbonization of buildings across the state.

Jun 26, 2024

The first-ever town-level spatial analysis of the effect of heat pump adoption on residential heating bills finds that air-source heat pump adoption will increase heating costs for approximately half of all Massachusetts households due to high electricity prices, challenging the state’s ability to achieve its recently announced ambitions for heat pump adoption.

Genworth Breaks Down the Basics of Long Term Care

The Thumb Loop system is designed to meet the maximum wind energy potential of Michigan�s Thumb region as well as contribute to regional system reliability and facilitate wholesale market competition.

Barbara Bermudo nos habla sobre el regreso al colegio y la importancia de donar leche

Conoce al legendario restaurador y mecánico Martín Vaca quien construye autos fuera de serie desde hace más de 50 años. MEXICÁNICOS, estreno el 2 de marzo a las 10PM

Trust is critical, especially for a person with autism and their family. Meet the Vollmert family and get a sense of how they approach daily life and planning for a financially secure future with their autistic son, Scott. Learn more: http://u.nm.com/1AQBAsN

Is a Nonsurgical Facelift a Reality and How Does it Impact Facial Aging?

Robert Kuske, MD

Download CA Intermediate Cost and Management Accounting Question Papers New Course Sep 2024 in PDF. For other question papers of CA Inter May 2024, Nov 2023, May 2023, Nov 2022, May 2022, Dec 2021, July 2021, Nov 2020, Nov 2019, May 2019, Nov 18, May 2018, Nov 2017, Nov 2016, May 2016, May 17, may 2016, CA IPC Nov 2015, CA IPC may 2015, CA IPC Nov 2014 check similar section. Previous years Taxation CA IPCC IPC question papers can also be downloaded using Search. You can also search and download may 2015 Final question papers here. We are providing ca final question papers of may 2016 for Financial Reporting FR, Advanced Financial Management AFM, Advanced Auditing and Professional Ethics, Taxation, Corporate & Allied Laws,Advanced & Management Accounting AMA, Direct Tax Laws DT, Indirect Tax Laws IDT and IPCC/IPC may 2015 question papers for Advanced Accounting , Business, Law, Ethics & Communications, Taxation, Advanced Accounting , Auditing & Assurance, Information Technology & Strategic Management ITSM.

Read The High Cost Of Lazy Reading

Manager: “[My Name], why are our material costs this month £2.5 million?!”

Read The High Cost Of Lazy Reading

New observations from the James Webb Space Telescope are exposing the pathways that water takes to reach terrestrial planets

Campaign shot by fashion photographer Jean Paul Goude...

The post Lacose Christmas campaign 2016 first appeared on peopleofdesign.

Alan Turing's theories about computation seem to have a startling consequence, placing hard limits on how fast or slow any physical process in the universe can grow

Prescribing non-steroidal anti-inflammatory drugs (NSAIDs) to high-risk individuals in England costs the NHS around 31 million and results in over 6,000

61% of Medicare-eligible adults have a medlinkBMI/medlink of 27 or higher, indicating they could potentially benefit from a GLP-1 receptor agonist like semaglutide for weight loss (!--ref1--).

Highlights: With the updated 2023 guideline, Australian physicians and reproductive health specialists offer better

The Indonesian Government has legislated to shoulder the value-added tax liability of retail businesses on rent and service charges due between August and October 2021.

New book urges fundamental re-think to unite farmers and conservationists for sustainable development. STOCKHOLM (4 SEPTEMBER 2013) — We must prioritize the health of ecosystems and water supplies if we are to grow enough food to feed the world’s rising population. This is the key message of the book Managing Water and Agroecosystems for Food […]

The post Healthy ecosystems are the key to productive agriculture first appeared on International Water Management Institute (IWMI).

2nd February 2014 – Colombo, Sri Lanka Agriculture and wetlands should be managed in unison in order to conserve vital ecosystems and support the livelihoods of millions of people, according to a new report published to coincide with World Wetlands Day, today. Download the full media release Download the report

The post Millions affected, billions at stake: Scientists urge ‘wiser’ use of wetlands to tackle poverty and conserve ecosystems first appeared on International Water Management Institute (IWMI).

IWMI Pakistan and Khwaja Fareed University of Engineering and Information Technology (KFUEIT), RYK join hands to organize an international workshop on Water, Energy, Food and Ecosystem (WEFE) Nexus for Indus Basin

The post International workshop on Water, Energy, Food and Ecosystem Nexus for Indus Basin first appeared on International Water Management Institute (IWMI).

Medical scientists are calling for greater investment in accessible, clean drinking water infrastructure to mitigate the health and environmental risks

The cost-effectiveness of artificial intelligence (AI)-supported detection of proximal caries was assessed by new study published in iInternational Association for Dental Research (IADR)/i.

Scientists have developed a groundbreaking vaccine offering a cost-effective approach to lower "bad" LDL cholesterol, responsible for perilous plaques

A groundbreaking portable device developed by a team of researchers at The University of Texas at El Paso can quickly and affordably detect colorectal

25% of Indians have varicose veins (!--ref1--), a condition often overlooked and treatable without surgery, according to leading medical experts. They

IWMI research shows that cocoa farmers in Ghana are interested in solar-powered irrigation pumps but face financial barriers. Policy changes and education are needed.

The post Cocoa farmers in Ghana show strong interest in solar-based irrigation, but pump costs are often too high first appeared on International Water Management Institute (IWMI).