Even though that perception is partly the creation of right-wing media, the Democrats surely need to hone their identity.

Death Stranding, originally launched in 2019, has finally come to Xbox consoles five years after its initial debut as a Director's Cut version from Hideo Kojima.

In Canada, your IP address has the right to remain silent. Elon Musk is suing OpenAI for not being Open. Apple faces a class action not allowing competitive access to backup services and the World Server Throwing Competition in March 2024 is accused of being too violent towards servers.   All this and more on the […]

Jill Parton, 46, suffered fatal injuries when she was hit by a freight train in Heaton Chapel in the early hours of June 3 this year, an inquest heard

A band that measures the acidity of sweat could flag if athletes or manual workers are overexerting themselves

More than 600 types of viruses that infect bacteria have been found living on toothbrushes and showerheads – and many of them have never been seen before

Popular weight-loss medications including Ozempic and Wegovy contain a drug that seems to decrease cravings for food and drugs – and now there’s evidence that it might make exercise less rewarding, too

A chemical produced by gut bacteria could be the basis for a non-invasive test for endometriosis – and mouse experiments suggest it might also help treat the condition

If you’ve ever tried to make a portrait that looks like the person you’re sketching, you know it’s no walk in the park. Maybe you’ve got the eyes perfectly, but then the mouth looks… well, let’s say “abstract.” So, how do the pros do it? What tools, materials, and techniques help bring out that jaw-dropping […]

The post Draw Portraits Like a Pro – Essential Tools and Materials for Photo-Realistic Results appeared first on Chart Attack.

On this timeline Russia is nearly a decade and a half behind SpaceX.

Broadcom acquisition was a "wake-up call" for VMware-dependent SMBs.

Music director and singer Adnan Sami said he was saddened by the demise of “one of the greatest Sarangi Maestros that the entire Indian subcontinent has ever witnessed”.

Cloud-based business management software (CRM, ERP) can revolutionise an SME.

‘They acted like Republicans for the last four months,’ Stewart lamented in a scathing monologue

SYDNEY and Brisbane are hot but there are two towns redefining the word “scorcher” and adopting bizarre solutions for dealing with the heat.

When chemist Dora Richardson’s employer decided to terminate the breast cancer research on the drug Tamoxifen in the early 1970s, she and her colleagues continued the work in secret.

The Orphan Drug Act (ODA) turned 30 this month, demonstrating that good laws really can have an enduring impact. Amidst the celebrations, a reporter asked me a provocative question: can we afford more orphan drugs costing hundreds of thousands of dollars per year? FDA Matters answered “yes.” However, I added a caveat that should worry everyone eager for orphan drugs to succeed. When genomics and personalized medicine become successful, this will multiply the number of rare diseases and the overall cost of orphan drugs, perhaps beyond what the system can bear.

This article is part of our exclusive IEEE Journal Watch series in partnership with IEEE Xplore.

Any imaging technique that allows scientists to observe the inner workings of a living organism, in real-time, provides a wealth of information compared to experiments in a test tube. While there are many such imaging approaches in existence, they require test subjects—in this case rodents—to be tethered to the monitoring device. This limits the ability of animals under study to roam freely during experiments.

Researchers have recently designed a new microscope with a unique feature: It’s capable of transmitting real-time imaging from inside live mice via Bluetooth to a nearby phone or laptop. Once the device has been further miniaturized, the wireless connection will allow mice and other test subject animals to roam freely, making it easier to observe them in a more natural state.

“To the best of our knowledge, this is the first Bluetooth wireless microscope,” says Arvind Pathak, a professor at the Johns Hopkins University School of Medicine.

Through a series of experiments, Pathak and his colleagues demonstrate how the novel wireless microscope, called BLEscope, offers continuous monitoring of blood vessels and tumors in the brains of mice. The results are described in a study published 24 September in IEEE Transactions on Biomedical Engineering.

Microscopes have helped shed light on many biological mysteries, but the devices typically require that cells be removed from an organism and studied in a test tube. Any opportunity to study the biological process as it naturally occurs in the in the body (“in vivo”) tends to offer more useful and thorough information.

Several different miniature microscopes designed for in vivo experiments in animals exist. However, Pathak notes that these often require high power consumption or a wire to be tethered to the device to transmit the data—or both—which may restrict an animal’s natural movements and behavior.

“To overcome these hurdles, [Johns Hopkins University Ph.D. candidate] Subhrajit Das and our team designed an imaging system that operates with ultra-low power consumption—below 50 milliwatts—while enabling wireless data transmission and continuous, functional imaging at spatial resolutions of 5 to 10 micrometers in [rodents],” says Pathak.

The researchers created BLEscope using an off-the-shelf, low-power image sensor and microcontroller, which are integrated on a printed circuit board. Importantly, it has two LED lights of different colors—green and blue—that help create contrast during imaging.

“The BLE protocol enabled wireless control of the BLEscope, which then captures and transmits images wirelessly to a laptop or phone,” Pathak explains. “Its low power consumption and portability make it ideal for remote, real-time imaging.”

Pathak and his colleagues tested BLEscope in live mice through two experiments. In the first scenario, they added a fluorescent marker into the blood of mice and used BLEscope to characterize blood flow within the animals’ brains in real-time. In the second experiment, the researchers altered the oxygen and carbon dioxide ratios of the air being breathed in by mice with brain tumors, and were able to observe blood vessel changes in the fluorescently marked tumors.

“The BLEscope’s key strength is its ability to wirelessly conduct high-resolution, multi-contrast imaging for up to 1.5 hours, without the need for a tethered power supply,” Pathak says.

However, Pathak points out that the current prototype is limited by its size and weight. BLEscope will need to be further miniaturized, so that it doesn’t interfere with animals’ abilities to roam freely during experiments.

“We’re planning to miniaturize the necessary electronic components onto a flexible light-weight printed circuit board, which would reduce weight and footprint of the BLEscope to make it suitable for use on freely moving animals,” says Pathak.

This story was updated on 14 October 2024, to correct a statement about the size of the BLEscope.

Chicken products cause an estimated 1 in 7 of the nation’s human Salmonella illnesses each year, partly because the pathogen can easily contaminate the environments where birds are raised. To reduce the risk that contaminated meat will reach consumers, poultry companies need measures that control the bacterium on farms where chickens are bred and raised.

Mar 14, 2024

Stephen Walt writes that those who favor foreign policy restraint believe the United States should trade and invest in other countries, encourage other states to do the same, and be open to managed immigration instead of building walls in a fit of xenophobia.

hello products are a solution to the struggle at the sink. This advertisement shows the frustrations moms and dads can face when it�s brush time and they need to negotiate with their kids to brush.

First Response� Unveils First Ever Bluetooth�-Enabled Pregnancy Test at CES

Here's 900 words about me coming to terms with the fact that I absolutely need to channel my anger over this pandemic

If you take the time to talk to African scammers, you can open up a lot about them.

Hi, all. Waiting is hard. So here are some pretty pics to distract you. 

Friday was the day I'd scheduled to take some time off, go for nice walk, and get some pictures of the fall foliage.

In typical 2020 fashion, it didn't go quite as planned… 

So I went with it.

Now for some pictures of inside things. I don't know about you, but this is a pretty stressful time for me, and I'm using every tool in my toolbox to stay healthy and well. One of those is — always — writing, and hardly anything gives me greater comfort than having fun with my writing tools.

I've explained before that I write by hand. Then, when I've written a sufficient amount that I start to worry about the house burning down, I transcribe my writing into a Word document, using voice recognition software. If you're curious about the kind of notebooks I've written in previously and what my writing used to look like — and if you're a writer who wants a reminder of how normal it is for writing to be hard — go check out my old post, Pictures of a Book Being Made. 

In recent years, I have some new tools.

Writing by hand has always been my way, even before I developed a disability that makes typing prohibitively painful. I'm left-handed, but not too long ago, after doing some realistic thinking about how much pain I work through on a daily basis, I began to teach myself to write right-handed, so that I can increase the likelihood I'll be able to write forever. 

Now, after much practice, I alternate between hands pretty regularly as I work. The right-handed writing is slower and messier, and my hand gets tired faster. But it's fine.

I've also started using smaller, lighter notebooks. This is partly to save my hands, and partly because the most recent books I've been writing feel different, and have been asking me for new supplies.

In particular, they're asking me for smaller, lighter, less intimidating notebooks — and stickers. :o)

I've been hunting for stickers that feel like my books. Stickers that match my characters, my plot, the feelings that imbue my story. Then, as I write, I plop the stickers onto the page… And it helps. It gives me ideas; it slows me down, so that my writing is more thoughtful; it gives me joy. 

I'll share some pictures of my stickers… And include, with some of them, samples of my right-handed writing, so you can see what I mean about that. Anytime you see handwriting, that's my right-handed work. And anytime you see a sticker created by an individual/independent artist, I have gotten permission to share it.

Here goes.

There's one more artist whose work I wanted to share, but I didn't get permission from her in time. Her Etsy shop is on a short break at the moment, but keep the shop of Helen Ahpornsiri in mind; she creates animals using pressed flowers and plants, and the results are beautiful.

And that's my distraction for today.

Everyone, give yourself a break over the next few days and then however long this takes. Try not to check the news compulsively; wear masks to protect the vulnerable; forgive yourself for being stressed out. And hang in there.

♥♥♥

Virtual-reality could assist researchers in decoding how emotions spur a decision to commit a crime

Animals that hibernate need a way to keep their blood flowing as their body temperature drops, and it seems that the mechanical properties of red blood cells may be key

In a wetland on the south coast of England, archaeologists dug up one of the oldest and most complete wooden tools ever found in Britain, which is around 3500 years old

Google DeepMind has been using its AI watermarking method on Gemini chatbot responses for months – and now it’s making the tool available to any AI developer

This or any DORK TOWER strip is now available as a signed, high-quality print, from just $25!  CLICK HERE to find out more! HEY! Want to help keep DORK TOWER going  – join the DORK TOWER Patreon and ENLIST IN THE ARMY OF DORKNESS TODAY! (We have COOKIES!) (And SWAG!) (And GRATITUDE!)

it's probably fine

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South Korean orphan Milton dreamed of making it to America, the land of his father. One day he seized his chance.

University fees are rising to £9,535, meaning students will be left in more debt after their course.