pera Why we are finally within reach of a room-temperature superconductor By www.newscientist.com Published On :: Tue, 07 May 2024 17:00:00 +0100 A practical superconductor would transform the efficiency of electronics. After decades of hunting, several key breakthroughs are inching us very close to this coveted prize Full Article
pera Sunlight-trapping device can generate temperatures over 1000°C By www.newscientist.com Published On :: Wed, 15 May 2024 17:00:48 +0100 A solar energy absorber that uses quartz to trap heat reached 1050°C in tests and could offer a way to decarbonise the production of steel and cement Full Article
pera Atoms at temperatures beyond absolute zero may be a new form of matter By www.newscientist.com Published On :: Fri, 07 Jun 2024 12:00:10 +0100 Physicists have coaxed a cloud of atoms into having a temperature beyond absolute zero and placed them in a geometric structure that could produce an unknown form of matter Full Article
pera Mexico Farm Tied to Stomach Bug Back in Operation By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Mexico Farm Tied to Stomach Bug Back in OperationCategory: Health NewsCreated: 8/27/2013 4:36:00 PMLast Editorial Review: 8/28/2013 12:00:00 AM Full Article
pera As Temperatures Fall, Heart Attacks May Rise By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: As Temperatures Fall, Heart Attacks May RiseCategory: Health NewsCreated: 8/29/2017 12:00:00 AMLast Editorial Review: 8/30/2017 12:00:00 AM Full Article
pera Temperature matters: the potential impact of thermoregulatory mechanisms in brain-body physiology [Special Section: Symposium Outlook] By genesdev.cshlp.org Published On :: 2024-10-16T07:18:56-07:00 Thermoregulation, responsible for maintaining a stable core temperature during wide fluctuations in external and internal thermal environments, is an iconic homeostatic process. However, we suggest that despite its fundamental physiological significance, the potential for required cool housing temperatures and thermoregulatory mechanisms to influence the interpretation of experimental data is not sufficiently appreciated. Moreover, although it is generally assumed that the major thermoregulatory pathways are well understood, here we discuss new research that suggests otherwise and reveals the emergence of a new wave of exciting ideas for this "old" field of research. Full Article
pera {Delta}9-Tetrahydrocannabinol Alleviates Hyperalgesia in a Humanized Mouse Model of Sickle Cell Disease [Special Section: Cannabinoid Signaling in Human Health and Disease] By jpet.aspetjournals.org Published On :: 2024-10-18T07:04:15-07:00 People with sickle cell disease (SCD) often experience chronic pain as well as unpredictable episodes of acute pain, which significantly affects their quality of life and life expectancy. Current treatment strategies for SCD-associated pain primarily rely on opioid analgesics, which have limited efficacy and cause serious adverse effects. Cannabis has emerged as a potential alternative, yet its efficacy remains uncertain. In this study, we investigated the antinociceptive effects of 9-tetrahydrocannabinol (THC), cannabis’ intoxicating constituent, in male HbSS mice, which express >99% human sickle hemoglobin, and male HbAA mice, which express normal human hemoglobin A, as a control. Acute THC administration (0.1–3 mg/kg–1, i.p.) dose-dependently reduced mechanical and cold hypersensitivity in human sickle hemoglobin (HbSS) but not human normal hemoglobin A (HbAA) mice. In the tail-flick assay, THC (1 and 3 mg/kg–1, i.p.) produced substantial antinociceptive effects in HbSS mice. By contrast, THC (1 mg/kg–1, i.p.) did not alter anxiety-like behavior (elevated plus maze) or long-term memory (24-hour novel object recognition). Subchronic THC treatment (1 and 3 mg/kg–1, i.p.) provided sustained relief of mechanical hypersensitivity but led to tolerance in cold hypersensitivity in HbSS mice. Together, the findings identify THC as a possible therapeutic option for the management of chronic pain in SCD. Further research is warranted to elucidate its mechanism of action and possible interaction with other cannabis constituents. SIGNIFICANCE STATEMENT The study explores 9-tetrahydrocannabinol (THC)’s efficacy in alleviating pain in sickle cell disease (SCD) using a humanized mouse model. Findings indicate that acute THC administration reduces mechanical and cold hypersensitivity in SCD mice without impacting emotional and cognitive dysfunction. Subchronic THC treatment offers sustained relief of mechanical hypersensitivity but leads to cold hypersensitivity tolerance. These results offer insights into THC's potential as an alternative pain management option in SCD, highlighting both its benefits and limitations. Full Article
pera Utility of Early Postoperative DWI to Assess the Extent of Resection of Adult-Type World Health Organization Grade 2 and 3 Diffuse Gliomas [CLINICAL PRACTICE] By www.ajnr.org Published On :: 2024-11-07T15:14:12-08:00 BACKGROUND AND PURPOSE: World Health Organization (WHO) grade 2 and 3 diffuse gliomas account for approximately 5% of primary brain tumors. They are invasive and infiltrative tumors and have considerable morbidity, causing progressive neurologic deterioration. The mean survival time is <10 years from diagnosis. Surgical debulking represents first-line management. The extent of resection is associated with progression-free and overall survival. Radiologic assessment of the extent of resection is challenging. This can be underestimated on early postoperative MRI, meaning that accurate assessment may be achieved only on delayed follow-up imaging. We hypothesized that DWI may help facilitate more reliable estimates of the extent of resection on early postoperative MRI. This study aimed to assess the utility of DWI in early postoperative MRI to evaluate the extent of resection. MATERIALS AND METHODS: A single-center observational cohort study was performed. All patients with histologically confirmed WHO grade 2 and 3 gliomas managed with surgical debulking between January 2015 and December 2020 were identified. Preoperative, early postoperative, and follow-up imaging were reviewed independently by 2 consultant neuroradiologists. The extent of resection was estimated with and without DWI sequences for each case. RESULTS: Two hundred twenty-four patients with WHO grade 2 and 3 gliomas were managed with surgical debulking between 2015 and 2020. DWI was not performed on early postoperative MRI in 2 patients. With the use of DWI, the extent of resection was upgraded in 30% of cases (n = 66/222) and classified as "complete" or "supramaximal" in 58% of these patients (n = 38/66). In cases in which the extent of resection was upgraded with the use of DWI, signal abnormality was stable or reduced at follow-up in 78% (n = 49/63). In cases with worsening signal abnormality, 64% were deemed to be secondary to adjuvant radiation therapy (n = 9/14). Eight percent (n = 5/63) of patients with an increased estimated extent of resection using DWI demonstrated signal progression attributed to true disease progression at follow-up. CONCLUSIONS: DWI is a helpful and reliable adjunct in differentiating residual tumor from marginal ischemia in early postoperative MRI in WHO grade 2 and 3 diffuse gliomas and increases the accuracy in assessing the extent of resection. It should be used routinely in these cases. Full Article
pera Preoperative Assessment of Meningioma Consistency Using a Combination of MR Elastography and DTI [RESEARCH] By www.ajnr.org Published On :: 2024-11-07T15:14:12-08:00 BACKGROUND AND PURPOSE: Preoperative assessment of meningioma consistency is beneficial for optimizing surgical strategy and prognosis of patients. We aim to develop a noninvasive prediction model for meningioma consistency utilizing MR elastography and DTI. MATERIALS AND METHODS: Ninety-four patients (52 ± 22 years old, 69 women, 25 men) diagnosed with meningioma were recruited in the study. Each patient underwent preoperative T1WI, T2WI, DTI, and MR elastography. Combined MR elastography–DTI model was developed based on multiple logistic regression. Intraoperative tumor descriptions served as clinical criteria for evaluating meningioma consistency. The diagnostic efficacy in determining meningioma consistency was evaluated by using a receiver operating characteristic curve. Further validation was conducted in 27 stereotactic biopsies by using indentation tests and underlying mechanism was investigated by histologic analysis. RESULTS: Among all the imaging modalities, MR elastography demonstrated the highest efficacy with the shear modulus magnitude (|G*|) achieving an area under the curve (AUC) of 0.81 (95% CI: 0.699–0.929). When combined with DTI, the diagnostic accuracy further increased (AUC: 0.88, 95% CI: 0.784–0.971), surpassing any technique alone. Indentation measurement based on stereotactic biopsies further demonstrated that the MR elastography–DTI model was suitable for predicting intratumor consistency. Histologic analysis suggested that meningioma consistency may be correlated with tumor cell density and fibrous content. CONCLUSIONS: The MR elastography–DTI combined model is effective in noninvasive prediction of meningioma consistency. Full Article
pera Man Utd fans DESPERATE for Alexis Sanchez to CELEBRATE if he scores against Arsenal By www.sport.co.uk Published On :: Fri, 25 Jan 2019 17:25:00 +0000 ALEXIS SANCHEZ returns to former club Arsenal tonight - and Manchester United fans are desperate to see him celebrate if he scores at the Emirates.. Full Article
pera Pornhub operator broke Canadian privacy law, watchdog rules By www.itbusiness.ca Published On :: Fri, 01 Mar 2024 02:51:21 +0000 The company behind Pornhub and other popular pornographic sites broke Canadian privacy law by allowing intimate images to be shared on its websites without the direct knowledge or consent of everyone depicted, the federal privacy commissioner has ruled. The Office of the Privacy Commissioner’s (OPC) investigation into Aylo (formerly MindGeek), one of the world’s largest […] The post Pornhub operator broke Canadian privacy law, watchdog rules first appeared on ITBusiness.ca. Full Article Privacy aylo privacy commissioner of Canada security strategies Top Story
pera In a Landmark Study, Scientists Discover Just How Much Earth's Temperature Has Changed Over Nearly 500 Million Years By www.smithsonianmag.com Published On :: Thu, 19 Sep 2024 18:00:00 +0000 Researchers show the average surface temperature on our planet has shifted between 51.8 to 96.8 degrees Fahrenheit Full Article
pera The Role of MES Consultants in Streamlining Manufacturing Operations By www.chartsattack.com Published On :: Sun, 29 Sep 2024 03:03:07 +0000 Manufacturing efficiency has always been a priority. As competition grows, optimizing every aspect of production becomes critical. Manufacturers turn to experts to make the right improvements and introduce systems that boost overall performance. One key area where many businesses seek help is through Manufacturing Execution Systems (MES). MES consultants play a pivotal role in achieving […] The post The Role of MES Consultants in Streamlining Manufacturing Operations appeared first on Chart Attack. Full Article Business Technology Manufacturing Operations MES Consultants Streamlining Manufacturing Operations
pera Law enforcement operation takes down 22,000 malicious IP addresses worldwide By arstechnica.com Published On :: Thu, 07 Nov 2024 23:12:23 +0000 Operation Synergia II took aim at phishing, ransomware, and information stealing. Full Article Biz & IT Security cybercrime Interpol police
pera Trudeau government bans TikTok from operating in Canada — but Canadians can still use it By www.cbc.ca Published On :: Wed, 06 Nov 2024 17:30:48 EST Citing national security concerns, the federal government has ordered TikTok to shutter its Canadian operations — but users will still be able to access the popular video app. Full Article News/Politics
pera What the federal ban on TikTok's Canadian operations means for you By www.cbc.ca Published On :: Thu, 07 Nov 2024 18:09:04 EST The federal government ordered an end to TikTok's Canadian operations on Wednesday, citing national security concerns. But its decision to keep the app itself available has privacy experts puzzled. Full Article News/Politics
pera Fancy a night at the Opera? By www.theaustralian.com.au Published On :: Wed, 11 Jan 2017 13:00:00 GMT Sydney Opera House is considering introducing a lottery for guests to stay for free in the landmark. Full Article
pera DoP releases operational guidelines for Strengthening of Medical Device Industry scheme By www.pharmabiz.com Published On :: Tuesday, November 12, 2024 08:00 IST The Department of Pharmaceuticals (DoP) has released the operational guidelines for the newly announced central sector scheme for Strengthening of Medical Device Industry (SMDI), aiming at providing Full Article
pera Researchers Explore How the Human Body Senses Temperature By www.pewtrusts.org Published On :: Fri, 18 Dec 2020 09:53:54 -0500 As winter arrives and daylight hours decrease, it gets easier to hit the snooze button and stay in bed. It turns out that there’s a scientific reason behind this phenomenon that helps to explain why people struggle to adjust their internal clocks—also known as circadian rhythm or sleep-wake cycle—when the weather turns colder. Full Article
pera 236332: US saw "additional opportunities" to embed own troops in Pakistan military’s FATA operations By www.thehindu.com Published On :: Sat, 21 May 2011 02:26:52 +0530 Full Article The Cables
pera 226157: Pakistan accepted U.S. military role in counter-insurgency operations By www.thehindu.com Published On :: Sat, 21 May 2011 02:27:09 +0530 Full Article The Cables
pera 207373: U.S. Special Forces embedded with Pakistan Special Services Group and Frontier Corps for operations in NWFP By www.thehindu.com Published On :: Sat, 21 May 2011 02:27:20 +0530 Full Article The Cables
pera 204652: US. "boots on the ground" were to accompany Pakistan Frontier Corps for a joint operation, but were "denied deployment" at the last minute By www.thehindu.com Published On :: Sat, 21 May 2011 02:27:36 +0530 Full Article The Cables
pera 204260: U.S. special forces were embedded with Pakistan troops in 2009 anti-Taliban operations in the North-West Frontier Province By www.thehindu.com Published On :: Sat, 21 May 2011 02:27:46 +0530 Full Article The Cables
pera 191725: Ambassador presses Menon to implement civil nuclear cooperation with U.S. By www.thehindu.com Published On :: Sat, 18 Jun 2011 01:17:10 +0530 The Indian civil nuclear bureaucracy understands it is "essential" to advance cooperation with the U.S., but claims progress is stymied by the inability of U.S. firms to share sensitive technical information pending the authorizations required under U.S. licensing regulations. Full Article The Cables
pera Poland's Azoty ramps up PDH/PP operations at Police By www.argusmedia.com Published On :: 08 Nov 2024 17:03 GMT Full Article Propylene Propane Polypropylene Poland Joint ventures and alliances Strategy Supply
pera The 50th Anniversary of GPS: New Avenues for Cooperating with Europe's Galileo By www.belfercenter.org Published On :: Apr 9, 2024 Apr 9, 2024 This paper delves into the evolution and future prospects of Global Navigation Satellite Systems (GNSS), with a particular focus on the United States' Global Positioning System (GPS) and Europe's Galileo. As GPS celebrates its 50th anniversary, it is a timely moment to assess its historical trajectory, current status, and future directions, especially considering the emergence of new competitors like China's BeiDou. Based on interviews with two GNSS experts from the European Commission, this study aims to analyze the potential for cooperation between GPS and Galileo, exploring avenues for collaboration and mutual learning. Full Article
pera Mapping a Path Forward for Arctic Cooperation with Russia: A Biodiversity Case Study By www.belfercenter.org Published On :: Apr 22, 2024 Apr 22, 2024 For most of this century, the Arctic has been a place of peaceful cooperation in science and environmental protection, an approach built on a foundation of multiple agreements reached in the twentieth century. The Russian invasion of Ukraine and the geopolitical reverberations of the war have disrupted or outright halted most collaboration between Western and Russian scientists and conservationists. Full Article
pera Current and Future Arctic Cooperation: Where to Next? By www.belfercenter.org Published On :: May 1, 2024 May 1, 2024 Viktoria Waldenfels MPA 2025 reflects on promising ways forward for Arctic cooperation.This study group, led by Arctic Initiative Senior Fellow Margaret Williams, is evaluating the costs and benefits of renewing cooperation with Russia on science and conservation issues. Full Article
pera Africa Beyond the Headlines: A Kaleidoscopic Exploration of Contemporary African Politics and International Cooperation By www.belfercenter.org Published On :: Jun 14, 2024 Jun 14, 2024 Dr. Gloria Ayee led a study group over the course of five sessions during the Spring of 2024, exploring the current pivotal moment on the African continent. Participants of the study group were invited to reflect on the role that international cooperation must play in supporting inclusive, sustainable development in Africa, as well as to move beyond outdated perspectives and learn about Africa’s profound transformation through trade, investments in clean energy and health, and youth empowerment initiatives. Full Article
pera Beyond the Headlines: A Kaleidoscopic Exploration of Contemporary African Politics and International Cooperation By www.belfercenter.org Published On :: Jun 21, 2024 Jun 21, 2024 Dr. Gloria Ayee led a study group over the course of five sessions during the Spring of 2024, exploring the current pivotal moment on the African continent. Reflecting back, Dr. Ayee highlights the key takeaways from the study group. Full Article
pera US-China Cooperation Remains Possible By www.belfercenter.org Published On :: May 6, 2024 May 6, 2024 Joseph S. Nye advocates for identifying areas for cooperation between the United States and China such as climate change and public health. Full Article
pera The Makers of the SPAM� Brand Team Up with Operation Gratitude and Veteran Sunny Anderson to Highlight the Return of the SPAMERICAN Food Truck Tour - Video One By www.multivu.com Published On :: 20 Apr 2016 09:15:00 EDT Video One Full Article Food Beverages Household Consumer Cosmetics Retail Supermarkets Household Products (vacuum cleaners supplies etc) New Products Services Broadcast Feed Announcements Corporate Social Responsibility Veterans MultiVu Video
pera They Say There’s No Room for Immigrants While Desperate Rural Towns Lie Empty All Across the Western World By tobiasbuckell.com Published On :: Tue, 16 Jul 2019 17:38:20 +0000 Here’s a thing I keep noticing, and it drives me nuts. In Italy, a ship captain is arrested for bringing immigrants to shore after rescuing from them near death at sea: The number of migrants reaching Italy’s shores has drastically diminished – just 2,800 so far this year – and the country is now led […] Full Article Life Log immigration western world
pera Competition and Cooperation By dreamcafe.com Published On :: Fri, 06 Aug 2021 00:42:57 +0000 The question of competition versus cooperation among humans has come up on my Twitter timeline again. It emerges every now and then, when someone desperate to find a defense for capitalism falls back on, “You socialists want to eliminate competition, but competition is a part of nature, so eliminating it is impossible.” Okay, let’s talk … Continue reading Competition and Cooperation Full Article Politics
pera Probability of operating an alarm clock Rubix cube, doable with hours of concentration Qauntum physicists have yet to unravel the mysteries By cheezburger.com Published On :: Tue, 22 Jun 2010 22:35:14 -0700 Probability of operating an alarm clock Full Article
pera Dengue Virus Grows More Virulent in Warmer Temperatures By www.medindia.net Published On :: medlinkDengue/medlink, a recurring tropical disease that experiences outbreaks during the monsoon season, becomes more aggressive and severe in animal Full Article
pera Increased Temperatures Pose Growing Dengue Risk By www.medindia.net Published On :: The escalating impact of climate change is anticipated to expand the reach of medlinkdengue/medlink, a mosquito-borne disease claiming thousands of Full Article
pera Predicting Global Dengue Patterns With Sea Surface Temperature Anomalies By www.medindia.net Published On :: Chinese scientists found that anomalies in tropical Indian Ocean sea surface temperatures can forecast the severity of global medlinkdengue outbreaks/medlink (!--ref1--). Full Article
pera World’s First Solar Irrigation Cooperative Receives Award By www.iwmi.org Published On :: Mon, 09 May 2016 11:33:15 +0000 Chief Minister of Gujarat, Smt Anandiben Patel awarded a certificate of appreciation to the Dhundi Saur Urja Utpadak Sahakari Mandali (DSUUSM). The post World’s First Solar Irrigation Cooperative Receives Award first appeared on International Water Management Institute (IWMI). Full Article Press releases ccafs solar solar water pumps sparc
pera Childhood Home Temperatures Predict Adult Thermostat Settings By www.medindia.net Published On :: The temperature of one's medlinkchildhood/medlink home and the sense of community connectedness can help predict how U.S. residents set their thermostats, Full Article
pera Sleep Well Before Surgery to Avoid Postoperative Delirium By www.medindia.net Published On :: Poor sleep in the month before surgery raises the risk of postoperative delirium, warns a new study. The findings of the study will be presented at Full Article
pera Development of a composite drought indicator for operational drought monitoring in the MENA region By www.iwmi.org Published On :: Wed, 06 Mar 2024 09:50:32 +0000 The composite drought indicator (CDI) supports operational drought management decision making in Jordan, Lebanon, Morocco and Tunisia. The post Development of a composite drought indicator for operational drought monitoring in the MENA region first appeared on International Water Management Institute (IWMI). Full Article Publications drought drought monitoring
pera IWMI and GWP promote water cooperation through a study tour to Central Asia By www.iwmi.org Published On :: Fri, 05 Jul 2024 10:20:46 +0000 The visit for water professionals from South Asia laid the groundwork for furthering dialogue on transboundary river management for water security. The post IWMI and GWP promote water cooperation through a study tour to Central Asia first appeared on International Water Management Institute (IWMI). Full Article News transboundary water management water security
pera Farmers urged to prepare for El Niño to trigger record-high temperatures By www.iwmi.org Published On :: Mon, 04 Sep 2023 11:09:59 +0000 IWMI and CIMMYT warn of changing climate patterns in South Africa. The post Farmers urged to prepare for El Niño to trigger record-high temperatures first appeared on International Water Management Institute (IWMI). Full Article In the media
pera IWMI and GWP promote water cooperation through a study tour to Central Asia By www.iwmi.org Published On :: Thu, 11 Jul 2024 04:49:57 +0000 The visit for water professionals from South Asia laid the groundwork for furthering dialogue on transboundary river management for water security. The post IWMI and GWP promote water cooperation through a study tour to Central Asia first appeared on International Water Management Institute (IWMI). Full Article In the media water cooperation
pera Warner Chilcott Reports Operating Results for the Quarter Ended March 31, 2010 By www.medindia.com Published On :: Warner Chilcott Reports Operating Results for the Quarter Ended March 31, 2010 Full Article
pera Bird Flu Virus Gets Killed at Cooking Temperature By www.medindia.net Published On :: Bird flu or avian influenza virus does not infect people as the virus is heat liable, degraded and killed when subjected to high temperature, said health experts. Full Article
pera How Aphy Transformed citizenM’s Operations With Automation By www.hospitalitynet.org Published On :: Tue, 12 Nov 2024 15:02:00 +0200 citizenM, a global leader in modern, affordable luxury hotels, has long prioritized offering a premium level of service. For that, they believe in empowering their team, rather than having them hindered by manual processes. This led them to seek a solution that could optimize their workforce capabilities. Full Article
pera India's first railway test track for high-speed trials to be operational in Dec 2025 By www.ibtimes.co.in Published On :: Sun, 10 Nov 2024 14:46:29 +0530 India's first dedicated railway test track, under construction in Rajasthan, is expected to be completed by December 2025 with a total investment of Rs 820 crore, according to the Ministry of Railways. Full Article