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Dora Richardson Took Her Research Underground to Develop Lifesaving Tamoxifen

When chemist Dora Richardson’s employer decided to terminate the breast cancer research on the drug Tamoxifen in the early 1970s, she and her colleagues continued the work in secret.




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Drug Channels News Roundup, September 2024: Inside JNJ’s Gross-to-Net Bubble, Optum Rx’s Private Label Biosimilars, Where Biosimilars Boom, Accumulators vs. Patients, and Steve Collis Retires

Autumn is here! Curl up with your favorite pumpkin-spiced blog and savor these acorns that we’ve squirrelled away for you:
  • Johnson & Johnson Innovative Medicines gives a peek inside its $43 billion gross-to-net bubble
  • Optum Rx joins the private label biosimilar bandwagon
  • Biosimilars boom for provider-administered drugs
  • Fresh evidence of how copay accumulators hurt patients
Plus, words of wisdom from Cencora's soon-to-be-former CEO Steve Collis.

P.S. Join my more than 58,000 LinkedIn followers for daily links to neat stuff along with thoughtful and provocative commentary from the DCI community.

There’s still time to request an invite to the inaugural Drug Channels Leadership Forum. Attendance will be highly limited. We have already begun extending invitations, so apply now to be considered. Click here to view the full agenda.

Read more »
       




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Drug Channels News Roundup, October 2024: Humira Price War Update, PA vs. Providers, IRA vs. Physicians, My AI Podcast, New DCI Jobs, and Dr. G on Copayments

Eeek! It's time for Drug Channels’ Halloween roundup of terrifying tales to share with your ghoulish fiends. This month’s tricks and treats:
  • Spooky! Blue Shield of California frightens away the gross-to-net bubble with its Humira biosimilar strategy
  • Vampiric! Prior authorization sinks its fangs into providers’ time
  • Wicked! How the IRA will put a stake through specialty physician practices
  • Eerie! Google’s monstrous AI podcasts leave me petrified
  • Zoinks! Join the vampire hunters at Drug Channels Institute
Plus, Dr. Glaucomflecken tells us a frightening tale of copayments.

P.S. Stretch out your arms and join the ever-growing zombie horde who shamble after me on LinkedIn. You’ll find my ghostly rantings along with commentary from the undead hordes in the DCI community.
Read more »
       




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Health boards say around half of pharmacies have expressed interest in providing COVID-19 vaccines

Around half of Wales’ community pharmacies have expressed interest to health boards in providing COVID-19 vaccinations as part of the national programme.




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Lessons From A Private Funding Round: Science, Relationships, And Experience

By Mike Cloonan, CEO of Sionna Therapeutics, as part of the From The Trenches feature of LifeSciVC An insightful piece on this blog following the JPM healthcare conference noted the “refreshing burst of enthusiasm” in the biotech sector. It’s true

The post Lessons From A Private Funding Round: Science, Relationships, And Experience appeared first on LifeSciVC.




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204652: US. "boots on the ground" were to accompany Pakistan Frontier Corps for a joint operation, but were "denied deployment" at the last minute





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H-Diplo|RJISSF Roundtable 15-26 on Hazelton, Bullets not Ballots

Jacqueline L. Hazelton's Bullets not Ballots: Success in Counterinsurgency Warfare (Cornell University Press, 2021) is the subject of a Roundtable Review.






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Garlock Bankruptcy Affects Individuals Who Worked Around Gaskets or Packing Containing Asbestos - Garlock Bankruptcy Overview Video

Garlock Bankruptcy Overview Video




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Gout & Uric Acid Education Society Hosts Roundtable Exploring Strategies for Elevating the Severity of Gout and Improving Access to Public Education and Treatment - Gout as a Serious Health Issue

Gout as a Serious Health Issue




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Error'd: What Goes Around

No obvious pattern fell out of last week's submissions for Error'd, but I did especially like Caleb Su's example.

Michael R. , apparently still job hunting, reports "I have signed up to outlier.ai to make some $$$ on the side. No instructions necessary."

 

Peter G. repeats a recurring theme of lost packages, saying "(Insert obligatory snark about Americans and geography. No, New Zealand isn't located in Washington DC)." A very odd coincidence, since neither the lat/long nor the zip code are particularly interesting.

 

"The Past Is Mutable," declares Caleb Su , explaining "In the race to compete with Gmail feature scheduling emails to send in the *future*, Outlook now lets you send emails in the past! Clearly, someone at Microsoft deserves a Nobel Prize for defying the basic laws of unidirectional time." That's thinking different.

 

Explorer xOneca explains this snapshot: "Was going to watch a Youtube video in DuckDuckGo, and while diagnosing why it wasn't playing I found this. It seems that youtube-nocookie.com actually *sets* cookies..?"

 

Morgan either found or made a funny. But it is a funny. "Now when I think about it I do like Option 3 more…" I rate this question a ????

 

[Advertisement] ProGet’s got you covered with security and access controls on your NuGet feeds. Learn more.




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Cloud-inspired material can bend light around corners

Light can be directed and steered around bends using a method similar to the way clouds scatter photons, which could lead to advances in medical imaging, cooling systems and even nuclear reactors




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24 Cute Chonky Cats Celebrating a Cheerful Carbs Season By Impurrsonating Your Round Thanksgiving Turkey

'Tis the season to get chonky, fa la la la la, la la la la. We love almost every holiday, but Thanksgiving and Christmas are the best ones because we get to eat as much delicious food as we want and no one can tell us otherwise. From pumpkin pie to turkey, to stuffing and cranberry sauce, we can't wet to get our chonk on and eat as many plates as we can. We also like to spread some of he holiday cheer to our cats by giving them a little extra treat on the holidays, if we can get chonky, why can't they?

These cheerful chonkers are celebrating carbs season in the cutest way pawssible. They are large and in charge, chunky yet funky, and purrfectly round for all the belly rubs you desire. The more belly there is, the more belly rubs to be had, and then, everyone is happy. So, embrace the chonk this holiday season, eat all the turkey, and remember to wear stretchy pants during holiday meals. Enjoy!






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Media Release: 18 Natural Infrastructure Innovations Confronting Climate Change from Underground

More than 5 billion people could suffer water shortages by 2050 due to climate change, Pincreased demand and polluted supplies, concluded the UN’s 2018 report on the state of the world’s water.

The post Media Release: 18 Natural Infrastructure Innovations Confronting Climate Change from Underground first appeared on International Water Management Institute (IWMI).




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Press Release: Groundwater in Peril – IWMI joins 700+ scientists and practitioners in urgent call for action on global groundwater

The call to action highlighted in Nature this week cites recent scientific breakthroughs on
groundwater’s vital role in supporting rivers globally.

The post Press Release: Groundwater in Peril – IWMI joins 700+ scientists and practitioners in urgent call for action on global groundwater first appeared on International Water Management Institute (IWMI).




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New project brings five African countries together to jointly manage region’s groundwater

The five Partner States of the Kavango Zambezi Transfrontier Conservation Area (KAZA TFCA) have joined forces with IWMI to manage groundwater resources spanning an area larger than Austria and Germany.

The post New project brings five African countries together to jointly manage region’s groundwater first appeared on International Water Management Institute (IWMI).




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Transforming the future of water at ground-breaking conference

The Transformative Futures for Water Security (TFWS) initiative is raising the ambition for water and bridging the gaps between science, policy and action.

The post Transforming the future of water at ground-breaking conference first appeared on International Water Management Institute (IWMI).













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Solar-powered farming is quickly depleting the world’s groundwater supply

Tushaar Shah, a Scientist Emeritus at IWMI, comments on the rapid spread of solar pumps among rural communities in many water-starved regions, including India.

The post Solar-powered farming is quickly depleting the world’s groundwater supply first appeared on International Water Management Institute (IWMI).







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Groundbreaking Ceremony for Sofitel Dublin Airport: A New Era of Luxury Hospitality in Ireland

Accor and the Arora Group are proud to announce the groundbreaking of the highly anticipated Sofitel Dublin Airport, a new luxury hotel set to redefine the hospitality experience at Ireland’s main international gateway. The hotel will feature 412 elegantly designed rooms and suites, an all-day dining restaurant, a tea salon, and a sky bar located on the 11th floor, offering stunning views of the airport and beyond. This franchised development project features a new-build Sofitel hotel located at Dublin Airport, set to open by late 2026 as a full-service luxury hotel comprising approximately 412 guest rooms. The hotel will be directly linked to the airport’s Terminal 2, providing seamless connectivity for travellers. The developer for this project is the Arora Group, a significant franchise partner of Accor in the UK and the owner of both the Sofitel London Heathrow Airport and the Sofitel London Gatwick Airport. In 2018, Arora was awarded the opportunity to develop this over €100 mill...




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Employees and Companies Have a Shared Responsibility for Ensuring Ground Transport Safety for Business Travel, According to New Report from FREENOW and GBTA

Both corporate travel managers and business travellers in Europe have a shared responsibility as well as opportunities to mitigate risk by making smart choices when it comes to ground transportation for business trips. This is according to a new report, titled Maximising Duty of Care: Choosing the Safest ‘Last Mile’ Option for Your Business Travel from FREENOW, Europe’s multi mobility app with taxi at its core, and the Global Business Travel Association (GBTA), the world’s largest business travel association.




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Travel around the soil of Immense warriors in Rajasthan

Culture is another name of Rajasthan and famous for their festivals and traditional fairs. While you are exploring this state where golden sand dune desert exist. So the desert may offer a magical view of sandy vastness that spread miles...




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Walk around the natural charm of the Taj

Every visitor thinks about the Taj Mahal when they make any trip to India. Regularly considered to be one of the seventh wonder of the world, Taj Mahal should be explored by all visitors at least once in the whole life. About this...




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Hedosophia leads $7M seed round into retail supply chain AI startup Ameba

Ameba takes the unstructured data in a retailer’s supply chain systems, sprinkles in some generative AI, and makes the whole thing more efficient. 

© 2024 TechCrunch. All rights reserved. For personal use only.




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Couchbase raises $105M Series G funding round

Couchbase, the Santa Clara-based company behind the eponymous NoSQL cloud database service, today announced that it has raised a $105 million all-equity Series G round “to expand product development and global go-to-market capabilities.” The oversubscribed round was led by GPI Capital, with participation from existing investors Accel, Sorenson Capital, North Bridge Venture Partners, Glynn Capital, […]

© 2024 TechCrunch. All rights reserved. For personal use only.




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Castiron serves up a $6M seed round to support ‘food artisans’

The pandemic hasn’t been easy for anyone, but the food service industry has been hit particularly hard. More than 90,000 restaurants and bars have closed, leaving workers unemployed in an already precarious industry. And those who kept their jobs faced the stressful demands of customer-facing work in a pandemic. In response to the changed industry […]

© 2024 TechCrunch. All rights reserved. For personal use only.




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Turkey’s Spyke raises $55M in a seed round to bring a social twist to casual mobile games

Istanbul has become a city to watch when it comes to casual gaming startups, boosted by the likes of Peak (acquired by Zynga for $1.8 billion) and Dream (valued at $1 billion in a funding round last year). Now, a new startup is announcing a major round of funding to make its own mark on […]

© 2024 TechCrunch. All rights reserved. For personal use only.




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Equity Monday: Quibi, two Boston rounds and a shift to pessimism

Hello and welcome back to Equity, TechCrunch’s venture capital-focused podcast, where we unpack the numbers behind the headlines. This is Equity Monday, our short-form week-starter in which we go over the weekend, look to the week ahead, talk about some neat funding rounds and dig into what is stuck on our minds. So, by section then: […]

© 2024 TechCrunch. All rights reserved. For personal use only.




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Kaszek Ventures leads a $15 million round in Chilean asset management startup, Fintual

Like other financial sectors in Latin America, the retail investing space is getting a facelift by local tech startups that are cashing in on the untapped potential for democratizing asset management in the region. One of those startups is Chilean-based Fintual, which today announced a $15 million round led by Kaszek Ventures, the largest fund […]

© 2024 TechCrunch. All rights reserved. For personal use only.




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Groupon cuts another 500 employees in second round of layoffs

Groupon has laid off another 500 employees in a bid to cut costs, the company said in an SEC filing last week. The e-commerce company had cut 500 jobs — nearly 15% of its workforce then — in August 2022. The company said this new set of layoffs will be spread across the first two […]

© 2024 TechCrunch. All rights reserved. For personal use only.




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Google’s Gemini API and AI Studio get grounding with Google Search

Starting today, developers using Google’s Gemini API and its Google AI Studio to build AI-based services and bots will be able to ground their prompts’ results with data from Google Search. This should enable more accurate responses based on fresher data. As has been the case before, developers will be able to try out grounding […]

© 2024 TechCrunch. All rights reserved. For personal use only.







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19-Year-Old Becomes Youngest Woman to Fly Around the World Solo

After landing her Shark UL aircraft in Belgium Thursday, 19-year-old Zara Rutherford became the youngest woman to fly solo around the world. Photo: Kurt Desplenter/Zuma Press