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Volkswagen's stake in Rivian grows to $5.8B, joint venture now formed

VW's taking a larger stake in Rivian, now up to $5.8 billion Rivian and VW's joint venture has formally been created The Rivian R2 in 2026 and a Volkswagen in 2027 will be the first vehicles to feature the new joint-venture electrical architecture The Volkswagen Group on Tuesday announced that it would up its investment in Rivian as the two...




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CAF WCL: Edo Queens walk tight rope after Masar stalemate

Edo Queens on Wednesday battled FC Masar of Egypt to a goalless draw in their second Group B match of the 2024 CAF Women’s Champions League in Morocco, leaving their chances of progressing to the semifinals in the balance, PUNCH Sports Extra reports. The Nigerian and West African champions still maintain their pole position on


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At UN climate talks, nations big and small get chance to bear witness to climate change

BAKU, Azerbaijan — When more than two dozen world leaders deliver remarks at the United Nations' annual climate conference on Wednesday, many have detailed their nations' firsthand experience with the catastrophic weather that has come with climate change. “Over the past year, catastrophic floods in Spain, Bosnia and Herzegovina as well as well as in southern Croatia have shown the devastating impact of rising temperatures,” said Croatia's prime minister, Andrej Plenkovic. “The Mediterranean, one of the most vulnerable regions, calls for urgent action.” The Greek prime minister said Europe and the world needs to be “more honest” about the trade-offs needed to keep global temperatures down. “We need to ask hard questions about a path that goes very fast, at the expense of our competitiveness, and a path that goes some much slower, but allows our industry to adapt and to thrive,” he said. His nation this summer was hammered by successive heat waves after three years of below-average rainfall. In Greece, the misery included water shortages, dried-up lakes and the death of wild horses. Other speakers on the list include Pakistan Prime Minister Shehbaz Sharif, whose nation has seen deadly flooding this year from monsoon rains that scientists say have become heavier with climate change. Just two years ago, more than 1,700 people died in widespread flooding. Pakistan has also suffered from dangerous heat, with thousands of people hospitalized with heatstroke this spring as temperatures soared to 47 degrees Celsius. Also on the list of speakers Wednesday is Bahamas Prime Minister Philip Edward Davis. Like many other countries in the Global South, the Bahamas has piled up debt from warming-connected weather disasters it did little to cause, including Hurricanes Dorian in 2019 and Matthew in 2016. Leaders have been seeking help and money from the Global North and oil companies. Early on Wednesday, ministers and officials from African nations called for initiatives to advance green development on the continent and strengthen resilience to extreme weather events — from floods to droughts — across the region. Plenty of big names and powerful countries are noticeably absent from COP29 this year. That includes the 13 largest carbon dioxide-polluting countries — a group responsible for more than than 70% of the heat-trapping gases emitted last year — were missing. The world’s biggest polluters and strongest economies — China and the United States — didn't send their No. 1s. Neither did India and Indonesia. But U.K. Prime Minister Keir Starmer was there, and he announced an 81% emissions reduction target on 1990 levels by 2035, in line with the Paris Agreement goal to limit warming to 1.5 degrees Celsius above pre-industrial times. That’s up from the 78% the U.K. had already pledged. The main focus of this year’s talks is climate finance — wealthier nations compensating poor countries for damages from climate change’s weather extremes, helping them pay to transition their economies away from fossil fuels and helping them with adaptation.





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UN nuclear chief heads to Iran for crucial talks

Tehran, Iran — International Atomic Energy Agency chief Rafael Grossi is set to visit Tehran on Wednesday for crucial talks on Iran's nuclear program, warning just ahead of his trip that room for maneuver is narrowing. His visit comes only two days after the defense minister of Iran's nemesis Israel warned the Islamic republic was "more exposed than ever to strikes on its nuclear facilities". Israel has long accused Iran of seeking to acquire nuclear weapons, a claim Tehran denies. The two countries have traded missile strikes this year, as tensions soar over Israel's war with Iran's allies, Hamas in Gaza and Hezbollah in Lebanon. The strikes have brought to the surface their years-long shadow war and fueled fears of a wider Middle East conflict. "The margins for maneuver are beginning to shrink," Grossi said in an interview with AFP ahead of his visit, adding that "it is imperative to find ways to reach diplomatic solutions". While the IAEA is allowed to carry out inspections in Iran, Grossi stressed the need for "more visibility" into Iran's nuclear program, given its scale and ambition. "They have a lot of nuclear materials that could be used eventually to make a nuclear weapon, the IAEA chief told CNN on Tuesday, adding: "They do not have a nuclear weapon at this point."  Trump's warning Grossi's trip comes after Donald Trump -- who pulled out of a hard-won nuclear deal with Iran negotiated under Barack Obama -- was voted back into the White House. Trump said last week that he was not seeking to harm Iran and instead wanted its people to have "a very successful country", while insisting "they can't have a nuclear weapon". In 2015, major world powers including the United States reached an agreement with Iran on its nuclear program after 21 months of talks. The text provided for an easing of international sanctions on Iran in exchange for guarantees that it would not seek nuclear weapons. But Trump withdrew from the agreement in 2018 before re-imposing US sanctions on Iran. A year later, Iran started to gradually roll back its commitments to the nuclear deal, which only allowed Tehran to enrich uranium to 3.65 percent purity. The IAEA says Iran has considerably increased its reserves of enriched uranium to 60 percent, close to the 90 percent needed to develop an atomic bomb. It is against this backdrop that Grossi is schedule to visit Iran for the first time since May. In a statement, the IAEA said it would hold "high-level meetings with the Iranian government" and conduct "technical discussions on all aspects". Cameras unplugged Iranian President Masoud Pezeshkian, who came to office in July with hopes of improving ties with the West and having sanctions lifted, favors a revival of the nuclear deal. But all efforts to get the nuclear agreement off life support have so far failed. The IAEA chief has repeatedly called for more cooperation from Iran. In recent years, Tehran has decreased its interaction with the UN agency by deactivating surveillance devices needed to monitor the nuclear program and effectively barring its inspectors. The foundations of Iran's nuclear program date back to the late 1950s, when the United States signed a civil cooperation agreement with Iran's then Shah Mohammad Reza Pahlavi. In 1970, Iran ratified the Non-Proliferation Treaty, which requires signatory states to declare and place their nuclear materials under the IAEA control. But with Iran threatening to hit back at Israel for its latest missile strikes, some lawmakers in the Islamic republic have called on the government to revise its nuclear doctrine to pursue nuclear weapons. The parliamentarians called on supreme leader Ayatollah Ali Khamenei, who wields ultimate authority in Iran, to reconsider his long-standing religious edict or fatwa banning nuclear weapons. The Islamic republic has maintained its policy against acquiring nuclear weapons, insisting its nuclear activities were entirely peaceful.          




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Heroes walk among us: This year’s JFNA General Assembly


At the conference, a full array of organizations, foundations, nonprofits, Israeli partners, lifelong activists, concerned citizens, and contributors made up the attendees.




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Kim Kardashian talks solo parenting struggles amid Kanye West absence

Kim Kardashian has recently reflected on navigating parenthood in the absence of her former husband Kanye West for 57 days.Speaking on November 12 episode of iHeart What The Winkler? Podcast, the SKIMS founder opened up about parenting alone these days without ex-husband Kanye, who is in Japan...




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Lahore’s dangerous smog: where disease and death stalk

“It’s been horrible; I’ve been sick on and off for the last 10 days,” said 29-year-old Natasha Sohail, who teaches A-Level students at three private schools in Lahore. She is asthmatic, and last week, her condition worsened with a vertigo attack and fever. “It’s criminal what is happening here,” said an incensed Sohail, referring to the “band-aid measures” taken by the Punjab government.

Lahore also has the distinction of being the world leader in the poor air quality index (AQI), with some neighbourhoods touching over 1,200 on the AQI this month. The AQI measures the level of fine particles (PM2.5), larger particles (PM10), nitrogen dioxide (NO2), and ozone (O3) in the air. An AQI of 151 to 200 is classified as “unhealthy”, 201 to 300 “very unhealthy” and more than 300 as “hazardous”.

For the past eight years, since Sohail was in college and since smog became an annual phenomenon, Sohail has relied on anti-wheezing drugs and inhalers. At home, there are four air purifiers to help her breathe cleaner air.

She’s not alone.

These two photos were taken at the same place; the clear blue sky was taken in September 2023 and the sepia skies in November 2024. Courtesy: Zaeema Naeem

“The hospitals are crowded with tens of thousands of patients suffering from respiratory and heart diseases being treated at hospitals and clinics over the last few weeks,” said Dr Ashraf Nizami, president of the Pakistan Medical Association’s Lahore chapter. “The psychological toll the poor air is taking on people remains under the radar.”

Punjab’s senior minister, Marriyum Aurangzeb, revealing the government’s anti-smog action plan, informed journalists that Lahore endured 275 days of unhealthy AQI levels over the past year, with temperatures rising by 2.3 degrees.

After Lahore’s AQI exceeded 1,000 last week, authorities closed all primary and secondary schools. Punjab’s Secretary for Environment, Raja Jahangir Anwar, warned the closure could continue if air quality doesn’t improve. “Young children are vulnerable, and we want to avoid an emergency,” he said, adding that online learning, like during the COVID pandemic, can be adopted again.

Source: Analysis by CREA. Data source for Lahore AQI is Airnow

Source: Analysis by CREA. Data source for Lahore AQI is Airnow

Source: Analysis by CREA. Data source for Lahore AQI is Airnow

Living in a world of air purifiers

Aliya Khan, 37, a mother of two boys — aged five and one, with the older one suffering from asthma — had installed four imported air purifiers in her home four years ago, each costing Rs31,000. They bought a fifth this year at Rs60,000. “It cost us a fortune, but that’s not all; the filters must be replaced every year, which costs Rs10,000 per machine,” she said.

The private school her five-year-old attends lacks air purifiers in classrooms, leaving parents with no choice but to pool together and buy one for their child’s classroom.

Khan, a development consultant, says air purifiers work best if the home is packed tightly to keep the air from outside entering. “Our windows and doors are poorly insulated and with elderly parents, domestic help and two kids — the air purifiers struggle to maintain their effectiveness.”

Smog brings business for some

Business picks up for 37-year-old Hassan Zaidi as soon as Lahore is covered in smog. He’s currently fulfilling an order for “hundreds of air purifiers” for a foreign school in Lahore.

A computer engineer with a passion for product design, Zaidi started building air purifiers in 2019 for his family after his baby daughter developed a cough. He purchased an imported air purifier, took it apart, and quickly realised that with the right materials, it was no “rocket science” to build one himself.

He claimed his “work better, look better, and cost just Rs25,000.” These air purifiers restart automatically after power outages, are nearly silent, and are easy to repair. The filter costs Rs2,400 and needs replacing each season. Each unit is good for a 500 square feet room if fully sealed.

Authorities take action

Stubble burning in India and Pakistan. The blue line is the border between the two countries. Pakistan (left) and India (on the right).

Anwar said the government has introduced several measures to reduce emissions and improve air quality, adopting a whole-of-government approach with all departments working together for the first time.

Authorities have already banned barbecuing food without filters and use of motorised rickshaws.

The government distributed 1,000 subsidised super-seeders to farmers as an alternative to burning rice stubble and took legal action against over 400 farmers who violated the burning ban. “This carrot and stick approach will be very effective,” endorsed Dr Abid Qaiyum Suleri, the executive director of the Islamabad-based think tank, Sustainable Development Policy Institute.

Anwar said super seeders will convert residue into mulch, improving production and speeding sowing. Penalising a few farmers will deter others from breaking the law.

“But the government’s own figures show agriculture contributes less than 4 per cent to smog,” pointed out Hassan Khan, a farmer in Punjab, and added, “Why waste so much time and expense on it; why not focus on the bigger polluters like the transport industry?”

Another measure the government took involved demolishing over 600 of the 11,000 smoke-emitting brick kilns that hadn’t switched to zigzag technology, including 200 in and around Lahore.

Terming brick kilns the “low hanging fruit,” Dr Parvez Hassan, senior advocate of the Supreme Court of Pakistan and president of the Pakistan Environmental Law Association, who, in 2003 and again in 2018, was appointed the chairperson of the Lahore Clean Air Commission and the Smog Commission by the Lahore High Court to come up with the smog policy, did not approve the “arbitrary decision of dismantling” the kilns. In his view, supporting the kiln owners with “available concessional financing for conversion to zizag technology” would be a more effective way.

He added that it was well known that the transport (oil), cement and textile sectors were the bigger polluters, but they were very influential. “Power in Pakistan has always meant being above the law,” he said, adding that the “general lack of political will and effective capability to monitor compliance” also acted as roadblocks.

“No country in the world has succeeded in good environmental policies unless it has first built a capacity to implement! The journey must begin with capacity building!”

However, Anwar said, action has been taken with visits to 15,000 industrial units, sealing 64 mills, and demolishing 152 factories.

With 43pc of air pollution in the province caused by unfit vehicles, Anwar also held the transporters responsible for the smog. He shared that Lahore has 1.3 million cars and 4.5 million two-wheelers, with 1,800 motorcycles added daily. He also mentioned that the traffic police had been ordered to impound vehicles without fitness certificates. Last month, a fine of Rs16.09 million was imposed on over 24,000 substandard vehicles across the province.

“Getting a vehicle fitness certificate in Pakistan is as easy as a blind person getting a license to drive!” said a petroleum expert who requested anonymity. “We need to clean the fuel, scrap old vehicles, and make vehicle emissions testing mandatory,” he added.

Imran Khalid, a climate governance expert, emphasised that improving fuel quality alone wasn’t enough; vehicles and engines also need upgrades to fully benefit from better fuel. He noted that while Euro 5 fuel is available in Pakistan, it’s not widely accessible, and Euro 6 is the standard in India. “I haven’t seen any survey on how many cars in Pakistan have Euro 5 compliant engines,” he added.

“I think it would be far more effective to invest in mass transit, but there is no talk of this issue; we keep making more motorways, widening roads, and bringing in more vehicles on roads in the cities instead of investing in railways and commuter rails,” said farmer Khan.

The petroleum expert urged the government to approve the refinery upgrade policy, which has been delayed for two years, adding that upgrades will take up to five years.

Despite various actions, people in Lahore remain unconvinced, calling them too little, too late.

“The measures announced by the government should have been operationalised at least six months before the smog season and the 24/7 enforcement of these priorities should be rigorously monitored by a dedicated team with support of the public through awareness campaigns,” pointed out advocate Hassan.

Nizami called for year-round efforts against air pollution, questioning why no one is held accountable for cutting millions of trees for unplanned housing while the focus remains on controlling stubble burning.

The Pakistan Air Quality Experts (PAQx) group, a coalition of 27 professionals from public health, environmental science, law, and economics, has written to the prime minister, suggesting the establishment of a “comprehensive, nationwide real-time air quality monitoring network” for informed decision-making and responsive policymaking.

Anwar defended the smog plan, stating it’d been in progress since April and required public cooperation, including staying indoors and wearing masks. Punjab’s senior minister, Marriyum Aurangzeb, warned that failure to wear masks could lead to a complete city lockdown.

“I don’t see the plan working as the air quality is getting from bad to worse,” said Sohail.

Nizami criticised the government for making a lot of noise but taking little action. “It’s shameful how they’ve shifted health responsibilities to the private sector,” he said.

Sohail suggested cloud seeding for artificial rain, noting its positive impact last year. Nizami also supported using artificial rain to clear the haze.

Anwar explained that cloud seeding required the right clouds and humidity. “But we are quite ready and as soon as the timing is right, we will do it,” he promised.

Climate diplomacy

While 70pc of smog in Lahore is locally generated, nearly 30pc comes from India. Manoj Kumar, a scientist with the Finnish Centre for Research on Energy and Clean Air, noted that the Indo-Gangetic Plain formed an “interconnected airshed,” affecting air quality, but local sources played a major role in Lahore’s pollution levels.

The chief minister is keen to start talks with her Indian counterpart. “Maryam Nawaz will soon send a letter to the Chief Minister of Indian Punjab, expressing her willingness to visit India and invite him to Pakistan,” said Anwar.

Kumar praised the Punjab chief minister’s initiative, emphasising that long-term, coordinated efforts between both countries could lead to improved air quality through a unified approach. But the efforts should not stop at the Punjab regions alone, as the airshed is shared and goes beyond India.

Anwar said Pakistan is considering hosting a “regional climate conference in Lahore soon.”


Header image: Smog near the Ghanta Ghar (Clock Tower) in Faisalabad, a city about 120km from Lahore and the third most populous city after Karachi and Lahore. Credits: Khalid Mahmood/Wiki & handout.

This article was originally published in Inter Press Service and has been reproduced here with permission.





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Rivian-Volkswagen partnership to produce EV tech for R2 model

Rivian is teaming up with Volkswagen in a $5.8 billion joint venture for EV innovation on its R2 model, which the company says will eventually be manufactured in Georgia.




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Canadian goalkeeper Crépeau's focus is always to accumulate small wins and greatness will follow

For Canadian men's soccer goalkeeper Maxime Crépeau, it's all about winning the small contest in front of you, and accumulate enough of those wins in succession, and greatness will follow.




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Using phone? Jaywalker hit and sent flying by taxi in Orchard

A woman was sent flying after she was hit by a car on Wednesday (Nov 13) morning. The incident occurred at the junction of Orchard Road and Handy Road. In a video posted to the SG Kaypoh Facebook group, the woman is seen crossing the road while the traffic light was not in her favour.   She appears to be looking down at her phone. The driver involved in the accident did not notice her till it was too late and collided with her head-on. In the video, the woman is sent flying and lands several metres in front of the car upon impact. She manages to sit up after landing, and looks stunned from the impact.   The driver and his passenger also rush out of the vehicle to assist.  Speaking to AsiaOne, the Singapore Civil Defence Force said that the female pedestrian was conveyed conscious to Tan Tock Seng Hospital. When contacted, the police said they were alerted to an accident involving a taxi and a pedestrian at the junction of Orchard Road and Handy Road on Nov 13 at about 3.15am.




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'Very stressful but thankful': Zhang Shuifa talks about returning to showbiz

When former TV actor Zhang Shuifa appeared in a sales livestream with some local celebs in July, it sparked nostalgia among netizens who hadn't seen him on screens for years. The 57-year-old's appearance then led to his gradual return to showbiz. Besides turning up in the occasional sales livestreams, the Malaysian is also currently filming local director Jack Neo's upcoming movie I Want To Be Boss, which is expected to be released during Chinese New Year next year. In an Instagram Reel today (Nov 14), Shuifa, who debuted in 1988 with Singapore Broadcasting Corporation (SBC, now Mediacorp), reminisced about the time he filmed a drama with local actor Collin Chee. "I remembered it was over 30 years ago, though I can't remember the name of the drama now," he said. Collin, 57, shared that it was his first drama in 1993.




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'I'm not allowed to talk about turtles anymore': 20+ Employees who had HR step in for the silliest reasons

Doing human resources work isn't always serious. Sometimes, it can be very funny, as the people of the internet will tell you!  

Though they're sometimes known as the company boogeyman, the human resources department is sometimes needed to step in and sort out employee relations. They have a broad range of job duties, from managing an office to hiring and firing to mediating employee disputes. This can result in some awkwardness at times. As these HR professionals can tell you, it can be very awkward to try and figure out which employee is the one stinking up the office with their BO or talking to an employee about wearing appropriate office attire. 

Still, these HR professionals managed to make the best out of their situations. U/sgy0003 asked people to share the "most ridiculous/hilarious complaints you ever received," and more than 2,700 people replied with their funniest tales. One person had to deal with an executive assistant who claimed her high heels prevented her from walking to the copier. Another got in trouble for their drawing of a stingray! You can check out all of these very silly tales down below. 

Up next, read about what happened when this 15-year-old called out her Grandmother for constantly missing her school concerts, leaving the whole family reeling. 




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Baby milk prices 'punish those who don't breastfeed'

Parents say they feel penalised by the high cost of formula, which cannot be discounted under the law.




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'Priyanka Chopra was out...': Arjun Kapoor talks about his terrific chemistry with Ranveer Singh in Gunday

Talking about Priyanka Chopra, Arjun admitted that she was already a big star when they made the film.




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Practical photocatalytic hydroalkylation of alkenes with chloroacetates mediated by the formate ion

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00228H, Research Article
Ekaterina V. Malakhova, Vladislav S. Kostromitin, Vitalij V. Levin, Alexander D. Dilman
Commodity chemicals are used as alkylating and reducing agents for radical addition to alkenes. The method is based on activation of the strong C–Cl bond by the radical anion of carbon dioxide.
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A Pd(II)-catalyzed denitrative alkyne annulation reaction for the synthesis of cyclopenta[b]chromanes

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00344F, Research Article
Pratiksha Bhorali, Deep J. Kalita, Babulal Das, Sanjib Gogoi
The first denitrative Pd(II)-catalyzed alkyne annulation reaction is reported for the synthesis of cyclopenta[b]chromanes.
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Photoredox catalyzed hydroazolylation of alkenes via phosphoranyl radicals

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00233D, Research Article
Fan Zhu, Zhi Qiao, Na He, Chunxiao Nong, Qiping He, Meilan Xi, Xizhong Song, Jun Lin, Jingbo Chen, Yi Jin
A general protocol for the hydroazolylation of alkenes with N-hydroxyl azoles is reported. These reactions proceed via a phosphoranyl radical, followed by radical coupling of the resulting azole radical to the alkene radical.
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Recent advances in the metal-catalyzed asymmetric alkene hydrogenation of cyclic conjugated carbonyl compounds

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00227J, Review Article
Min Tan, Bram B. C. Peters, Pher G. Andersson, Taigang Zhou
This review summarizes the recent advances (2016–2023) in the stereoselective metal-catalyzed hydrogenation of cyclic α,β-unsaturated ketones, lactams and lactones since considerable developments were made. Where possible the application of these methodologies in synthesis is outlined.
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Palladium-catalyzed [4 + 4] cycloaddition of 2-pyrones with 2-alkylidenetrimethylene carbonates: access to bridged eight-membered oxygen heterocycles

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00329B, Research Article
Huawei Lin, Biming Mao, Bing Han, Jiayi Luo, Yanqing Ge, Xuerui Zhang, Chang Wang, Hongchao Guo, Chunhao Yuan
A novel palladium-catalyzed [4 + 4] cycloaddition of 2-pyrones with 2-alkylidenetrimethylene carbonates has been developed for the synthesis of bridged eight-membered oxygen heterocycles in good yields and with excellent stereoselectivities.
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Computational insights into the synergistic interplay of ligand and fluorine effects in palladium-catalyzed regiodivergent decarboxylative allylic alkylation

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00147H, Research Article
Shiyu Wang, Hongli Wu, Xiangyang Tang, Genping Huang
DFT calculations were performed to investigate palladium-catalyzed decarboxylative allylic alkylation of allyl difluoro-β-ketoesters. The synergistic effects of ligand and fluorine substituents on regioselectivity were uncovered.
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Stereodivergent synthesis of chiral spiropyrazolones through Pd-catalyzed asymmetric sequential hydroalkylation of 1,3-enynes: unusual solvent effects on the enantioselectivity

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00358F, Research Article
Shan Wang, Long Li, Yifei Zheng, Luqing Li, Yingcheng Wang, Fangzhi Peng, Zhihui Shao
Chiral spiropyrazolones were constructed through Pd-catalyzed asymmetric sequential hydroalkylation of 1,3-enynes. Four stereoisomers could be obtained through substrate control and chiral ligand control.
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Iodine-catalyzed intermolecular 1,2-thio (seleno)amination of alkenes with 1,2,3-triazoles and disulfides (diselenides) in air

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00246F, Research Article
Jian Ji, Xuwen Chen, Zongjing Hu, Cong Guan, Jinhua Liu, Yaqi Deng, Shunying Liu
Iodine-catalyzed 1,2-thio (seleno)amination of alkenes via direct N- and C-centered radical cross-coupling was established to elicit highly regioselective β-triazolized thioalkyl compounds.
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Base-induced azofluoroalkylation of unactivated alkenes via halogen atom transfer

Org. Chem. Front., 2024, 11,2161-2170
DOI: 10.1039/D3QO02114A, Research Article
Jing Zhang, Yanchuang Zhao, Yu-Yi Zhu, Peng Lei, Hanru Liu, Chang-Sheng Wang, Shuya Xing, Yong Liu, Shao-Fei Ni, Thomas Castanheiro, Li-Wen Xu, Xinxin Shao
A base-induced three-components coupling employing unactivated alkenes, fluoroalkyl iodides and diazonium salts under mild reaction conditions has been developed.
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Rhodium-catalyzed C–C bond alkenylation and arylation of α-branched N-sulfonyl amines

Org. Chem. Front., 2024, 11,2182-2188
DOI: 10.1039/D3QO02140H, Research Article
Lun Xu, Yucheng Liu, Hang Shi, Lun Li
In this work, we described a rhodium-catalyzed C–C bond cleavage of α-branched amines via β-carbon elimination, then formed a five-membered rhodacycle intermediate, which can be captured by styrene(alkenylation) or silane(arylation).
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Visible light/copper catalysis enabled Heck-like coupling between alkenes and cyclic sulfonium salts via selective C–S bond cleavage

Org. Chem. Front., 2024, 11,2195-2200
DOI: 10.1039/D3QO02009F, Research Article
Xianqin Liu, Xufeng Li, Linyuan Wang, Yongjia Shi, Jian Lv, Daoshan Yang
A Heck-like coupling of cyclic sulfonium salts with alkenes via selective C–S bond cleavage using a copper complex as a photosensitizer through a visible-light-driven redox-neutral process has been developed.
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Electrode-switchable: exploring this new strategy to achieve regiodivergent azidoiodination of alkenes

Org. Chem. Front., 2024, 11,2189-2194
DOI: 10.1039/D3QO01935G, Research Article
Xin-Lei Sun, Chen-Xi Xia, Yue Ren, Yu-Jin Li, Zhi-Qian Cao, Ling-Guo Meng
An “electrode-switchable” organic electrochemistry method for the azidoiodination of alkenes, where the choice of anode dictates the regiodivergent alkene azidoiodination, reveals a novel pathway for controlled regioisomers.
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Origin of site-selectivity of hydrogen atom transfer in carbohydrate C–H alkylations via photoredox catalysis

Org. Chem. Front., 2024, 11,2269-2276
DOI: 10.1039/D4QO00073K, Research Article
Yujie Ji, Lingfei Hu, Han Gao, Yan-Bo Wu, Xiangying Lv, Gang Lu
Two major factors, i.e., C–H σ orbital energy and C–H BDE, account for the HAT site-selectivity of carbohydrates with the quinuclidine radical cation.
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Electron donor–acceptor complex photoactivation for deaminative alkynylation, alkenylation and allenylation: a comprehensive study

Org. Chem. Front., 2024, 11,2231-2240
DOI: 10.1039/D4QO00177J, Research Article
Romain Lapierre, Lina Truong, Matthieu Hedouin, Hassan Oulyadi, Bruno Schiavi, Alexandre Jean, Philippe Jubault, Thomas Poisson
Herein, we disclose our study toward photoinduced deaminative alkynylation, alkenylation and allenylation.
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Fe-catalyzed B–H and Si–H insertion reactions of gem-dihaloalkanes

Org. Chem. Front., 2024, 11,2241-2248
DOI: 10.1039/D4QO00136B, Research Article
Xinyu Wang, Zhaobin Wang
We present an approach involving Fe-catalyzed B–H and Si–H insertion of gem-dichloroalkanes. In contrast to previous strategies, our method uses gem-dihaloalkanes as non-stabilized carbene precursors and operates through a radical reaction pathway.
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Frustrated Lewis pair chemistry of alkynes

Org. Chem. Front., 2024, 11,2375-2396
DOI: 10.1039/D4QO00217B, Review Article
Jing Guo, Maying Yan, Douglas W. Stephan
This review is focused on the chemistry of frustrated Lewis pairs (FLPs) with alkynes and surveys the range of stoichiometric and catalytic reactions enabled by this concept.
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Photoinduced alkylation of pyrazolones via β-scission of unstrained aliphatic alcohol derivatives

Org. Chem. Front., 2024, 11,2289-2296
DOI: 10.1039/D4QO00077C, Research Article
Xinxin Geng, Pan Tao, Yujun Li, Ke Zheng
An efficient radical approach was reported for the transformation of unstrained aliphatic alcohols through the β-scission of alkoxyl radicals.
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Nickel/photoredox-catalyzed carbonylative transformations of α-phosphorus-, α-sulfur-, and α-boron-substituted alkyl halides

Org. Chem. Front., 2024, 11,2297-2305
DOI: 10.1039/D4QO00167B, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Le-Cheng Wang, Xiao-Feng Wu
A novel dual nickel/photoredox catalyzed direct amino- and alkoxycarbonylation of α-heteroatom substituted organohalides has been developed.
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Advancement in the C–H bond alkylation of (hetero)arenes catalyzed by the most abundant transition metal–iron

Org. Chem. Front., 2024, 11,2397-2417
DOI: 10.1039/D4QO00063C, Review Article
Chandini Pradhan, Benudhar Punji
Advancement in the direct C–H bond alkylation of arenes and heteroarenes using the catalysts based on the most abundant transition metal, iron, is summarized.
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Metal-free photoinduced denitrogenative alkylation of vinyl azides with alkyl radicals toward ketones

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00280F, Research Article
Hui Yin, Siqi Jian, Xiujuan Feng, Ming Bao, Xuan Zhang
A metal-free method for the synthesis of ketones via a visible-light induced denitrogenative alkylation of vinyl azides with alkyl radicals is presented.
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Copper-catalyzed oxidative sulfenylation and alkylation of indolin-2-ones for direct construction of sulfur-substituted quaternary carbons

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00491D, Research Article
Yun-Hao Zhang, Yi-Nuo Wang, Zi-Yu Liu, Si-Han Zheng, Guang-Lin Li, Dexin Feng, Da-Zhen Xu
A rapid and green one-pot access to S-substituted quaternary carbon centers from commercially available feedstock chemicals has been established, providing complex molecules with high chemoselectivity by the use of air as the terminal oxidant.
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Photochemical [2 + 2 + 1] annulation of 2-vinyloxy arylalkynes with bromomalonates via energy transfer

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00249K, Research Article
Shuo Tang, Jiupeng Liu, Min Zhang, Dan Wang, Yong Wang, Jingjing Zhao, Pan Li
A transition-metal-free, oxidant-free and base-free photochemical [2 + 2 + 1] radical annulation of 2-vinyloxy arylalkynes with bromomalonates has been developed.
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Halogen-Bond-Promoted Direct Cross-Coupling of Ethyl 3-bromo-3-alkyl-2,2-difluoropropanoate with Coumarins/Quinolinones

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO00484A, Research Article
Guoliang Pu, Shi-Yuan Song, Jian Yang, Peng Guo, Jia Jia, Peijun Liu, Xuefei Li, Ping Liu, Chun-Yang He
Herein, we developed a practical method for the direct cross-coupling of ethyl 3-bromo-3-alkyl-2,2-difluoropropanoate with coumarins/quinolinones, leveraging a halogen bond as the pivotal non-covalent interaction. Employing this protocol, a library of...
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Selective nickel-catalyzed disulfuration of alkyl halides with di/trithiosulfonates

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00411F, Research Article
Lulu Liu, Jiaqi Hou, Yingying Ma, Hongwei Wang, Yu Zhong, Fangcan Liang, Luyao Wang, Qingling Wang, Ji-Quan Liu, Wen-Hua Xu, Dianhu Zhu
Selective reductive disulfuration of alkyl halides with di/trithiosulfonate reagents was developed through ligand regulation, with key features of broad substrate scope, good tolerance and excellent selectivity to disulfides over trisulfides.
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Metal–support interaction triggered d–p orbital hybridization for efficient electrocatalytic semi-hydrogenation of alkynes

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D4TA01240B, Paper
Qiong Wan, Jiaxun Zhang, Xuan Liu, Huizhi Li, Abdullah, Taotao Ren, Qiyuan Liu, Yongheng Xu, Jia Liu, Jicheng Liu, Bingqing Yao, Yiyun Fang, Xinzhe Li, Chi He
Atomic restructuring in Pd/Fe2O3 catalysts weakens Pd binding to chemisorbed 4-aminophenylacetylene and hydrogen intermediates, boosting conversion and selectivity in 4-aminophenylacetylene semi-hydrogenation, surpassing Pd/C and other catalysts.
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In situ analysis of the oxygen evolution reaction on the CuO film in alkaline solution by surface interrogation scanning electrochemical microscopy: investigating active sites (CuIII) and kinetics

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D4TA00628C, Paper
Seokjun Han, Jinoh Yoo, Won Tae Choi
Surface interrogation scanning electrochemical microscopy was employed to assess the electrocatalytic activity of CuO films for the oxygen evolution reaction in an alkaline solution.
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Machine Learning Enabled Exploration of Multicomponent Metal Oxides for Catalyzing Oxygen Reduction in Alkaline Media

J. Mater. Chem. A, 2024, Accepted Manuscript
DOI: 10.1039/D4TA01884B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Xue Jia, Hao Li
Low-cost metal oxides have emerged as promising candidates used as electrocatalysts for oxygen reduction reaction (ORR) due to their remarkable stability under oxidizing conditions, particularly in alkaline media. Recent studies...
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Afghanistan attends U.N. climate talks for first time since Taliban return to power

Afghanistan’s first delegation at United Nations climate talks since the Taliban’s return to power in 2021 has arrived in Baku, Azerbaijan




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Stachydrine, a pyrrole alkaloid with promising therapeutic potential against metabolic syndrome and associated organ dysfunction

RSC Med. Chem., 2024, 15,3652-3673
DOI: 10.1039/D4MD00425F, Review Article
Semim Akhtar Ahmed, Prasenjit Manna, Jagat Chandra Borah
Metabolic syndrome is a multifaceted condition marked by interconnected risk factors, significantly increasing the risk of serious diseases like cardiovascular disease, type 2 diabetes, and stroke.
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Pyridinyl 4-(2-oxoalkylimidazolidin-1-yl)benzenesulfonates and their hydrochloride salts as novel water soluble antimitotic prodrugs bioactivated by cytochrome P450 1A1 in breast cancer cells

RSC Med. Chem., 2024, 15,3728-3745
DOI: 10.1039/D4MD00476K, Research Article
Vincent Ouellette, Chahrazed Bouzriba, Atziri Corin Chavez Alvarez, Quentin Bruxelles, Geneviève Hamel-Côté, Sébastien Fortin
New water soluble antimitotic CYP1A1-activated prodrugs named PYRAIB-SOs and their hydrochlorides targeting breast cancers.
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Afghanistan attends U.N. climate talks for first time since Taliban return to power

Afghanistan’s first delegation at United Nations climate talks since the Taliban’s return to power in 2021 has arrived in Baku, Azerbaijan




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Kolkata’s Anish who is little master of the board after becoming youngest rated chess player at 3




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SketchNotes of My Talk: “How to Make More Money from Your Business”

In October I spoke at Dan & Ian’s DCBKK event in Bangkok, Thailand about how to make more money from your business. Through the mad illustration skills of one Maggie Appleton, here are SketchNotes summarizing my entire talk in a single image (click the image for a hi-res version).

The post SketchNotes of My Talk: “How to Make More Money from Your Business” first appeared on Rob Walling - Serial Entrepreneur.




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The 3 Aspects of a Great Conference Talk

When I started public speaking in 2008 I was really bad. Nervous. Content didn’t land. Often times I didn’t “get” my audience. I spoke a few times in 2008/2009, but it wasn’t until 2010 when I made strides towards getting better. As I did it I stumbled upon a framework of how I view publicRead More →

The post The 3 Aspects of a Great Conference Talk first appeared on Rob Walling - Serial Entrepreneur.