groups

Subperiodic groups, line groups and their applications

Understanding the symmetries described by subperiodic groups – frieze, rod and layer groups – has been instrumental in predicting various properties (band structures, optical absorption, Raman spectra, diffraction patterns, topological properties etc.) of `low-dimensional' crystals. This knowledge is crucial in the tailored design of materials for specific applications across electronics, photonics and materials engineering. However, there are materials that have the property of being periodic only in one direction and whose symmetry cannot be described by the subperiodic rod groups. Describing the symmetry of these materials necessitates the application of line group theory. This paper gives an overview of subperiodic groups while briefly introducing line groups in order to acquaint the crystallographic community with these symmetries and direct them to pertinent literature. Since line groups are generally not sub­periodic, they have thus far remained outside the realm of symmetries traditionally considered in crystallography, although there are numerous `one-dimensional' crystals (i.e. monoperiodic structures) possessing line group symmetry.




groups

SUBGROUPS: a computer tool at the Bilbao Crystallographic Server for the study of pseudo-symmetric or distorted structures

SUBGROUPS is a free online program at the Bilbao Crystallographic Server (https://www.cryst.ehu.es/). It permits the exploration of all possible symmetries resulting from the distortion of a higher-symmetry parent structure, provided that the relation between the lattices of the distorted and parent structures is known. The program calculates all the subgroups of the parent space group which comply with this relation. The required minimal input is the space-group information of the parent structure and the relation of the unit cell of the distorted or pseudo-symmetric structure with that of the parent structure. Alternatively, the wavevector(s) observed in the diffraction data characterizing the distortion can be introduced. Additional conditions can be added, including filters related to space-group representations. The program provides very detailed information on all the subgroups, including group–subgroup hierarchy graphs. If a Crystallographic Information Framework (CIF) file of the parent high-symmetry structure is uploaded, the program generates CIF files of the parent structure described under each of the chosen lower symmetries. These CIF files may then be used as starting points for the refinement of the distorted structure under these possible symmetries. They can also be used for density functional theory calculations or for any other type of analysis. The power and efficiency of the program are illustrated with a few examples.




groups

Americans Have Worse Health Than People in Other High-Income Countries - Health Disadvantage Is Pervasive Across Age and Socio-Economic Groups

On average, Americans die sooner and experience higher rates of disease and injury than people in other high-income countries, says a new report from the National Research Council and Institute of Medicine.




groups

Designing Learning Experiences with Attention to Students’ Backgrounds Can Attract Underrepresented Groups to Computing

Learning experiences in computing that are designed with attention to K-12 students’ interests, identities, and backgrounds may attract underrepresented groups to computing better than learning experiences that mimic current professional computing practices and culture do, says a new report from the National Academies of Sciences, Engineering, and Medicine.




groups

Systems for Providing Protection from Inhalation Hazards Should Extend to the Public and Broader Groups of Workers, Says New Report

The COVID-19 pandemic and more frequent wildfires have highlighted the need for respiratory protection for the public and all types of workers, including essential and gig economy workers. A new report recommends frameworks to ensure both groups receive timely access to appropriate respiratory protective devices and guidance on their effective use.




groups

IndiaAI 2023: MeitY’s 7 working groups for deploying AI to make governance smarter, data-led

“To ensure the sustainability of the CoE, robust collaboration with the Industry, and the creation of commercially viable outputs, the MeitY will not own any IP generated by the CoE. The IP generated can be retained by the idea generator or by the CoE.”




groups

6 groups every plumber should join

Plumbers are typically independent and work alone from a service truck, but there are significant benefits to joining groups. These can include learning from peers and expanding your customer base. Consider joining these six groups as a plumber.




groups

Health groups join forces to help Americans control blood pressure

In a move toward meeting goals for better cardiovascular health in the United States over the next decade, the American Heart Association (AHA) is joining the Centers for Disease Control and Prevention’s National Hypertension Control Roundtable (NHCR)® along with other founding members in a public, private and non-profit collaboration committed to increasing blood pressure control rates to 80% by 2025.




groups

Health groups urge Supreme Court to uphold Affordable Care Act

Patient and health advocacy groups representing millions of Americans with pre-existing conditions are applauding the U.S. Supreme Court’s decision to hear arguments in the case of Texas v. United States this term. The case is the latest court challenge to the health care law known as the Affordable Care Act (ACA). The groups filed an amicus brief urging the Court’s swift action and citing the detrimental impacts and uncertainty patients would face were the case left at the lower court level.




groups

Leading national groups voice ‘full support’ for prohibiting menthol cigarettes and all flavored cigars

WASHINGTON, D.C., November 5, 2023 — Weeks after the Food and Drug Administration (FDA) sent rules to end the sale of menthol cigarettes and all flavored cigars to the White House Office of Management and Budget for final review, the American Heart ...




groups

Littler Appoints New Leadership to Its Affinity Groups and Diversity & Inclusion Council

(March 22, 2021) – Littler, the world’s largest employment and labor law practice representing management, is pleased to announce new leadership for its ‘Ohana and Reunión affinity groups. Additionally, the firm’s Diversity & Inclusion (D&I) Council added six new members.




groups

The Promise and Perils of Affinity Groups; Or, How Not to Bargain with your Employee Resource Group

A properly structured and implemented Affinity Group (AKA Employee Resource Group) is a powerful tool in an employer’s Diversity Equity & Inclusion tool belt. But, unwary employers may risk violating the National Labor Relations Act if they bargain with an Affinity Group. In this month’s podcast, Alyesha Asghar Dotson discusses the do’s and don’ts of interacting with an active Affinity Group within your organization.
  




groups

ETSI to transform the standards development landscape with Software Development Groups

Sophia Antipolis, 2 February 2023

ETSI, the organization for globally applicable standards for information and communication technology (ICT), has adopted a new instrument, Software Development Groups (SDGs). This game-changing move will help ETSI adapt to the ever-evolving landscape of technology and standards development. Developing software to accompany standards will accelerate the standardization process, providing faster feedback loops and improving the quality of standards.

Read More...




groups

Investor Alert: Fraudulent social media “investment groups” take advantage of unsuspecting investors

TORONTO – The Canadian Securities Administrators (CSA) warns Canadians about fraudulent “investment groups” promoted on social media like Facebook and Instagram. These groups could be running a scam called a “pump and dump.”How the scam works:





groups

CTA Joins Government Agencies and Nonprofit and Private Groups to Host A Second Citywide Career Fair

Following the success of the first Citywide Career Fair last Spring, where over 60 employers and more than 400 job seekers attended, the Chicago Transit Authority (CTA) is joining local and state government agencies, nonprofits and private sector leaders to host a second joint hiring event next week.




groups

Trade Groups Report Productive Meetings with Washington Lawmakers

The AHRI’s 2024 Policy Symposium brought more than 200 members, along with AHRI staffers and others in HVAC, to Washington for the lobbying effort, plus panel discussions, keynote speeches, and networking.




groups

Trade Groups File Challenge to DOE Furnace Rule

The final rule from the U.S. Department of Energy, issued recently, requires newly manufactured indoor residential gas furnaces to be at least 95% efficient starting in December 2028, meaning furnaces made after then will have to be condensing models.




groups

Yahoo Groups Dropped RSS Feed Support

The RSS feeds of the RSS-Public and RSS-Board mailing lists are no longer available. Yahoo Groups used to offer feeds for each of its public lists, but Yahoo dropped support last year. A member of the service's product team said the feature was retired in July 2013.

To read the lists and subscribe to receive them in email, visit the Yahoo Groups pages for RSS-Public and RSS-Board.

We may move the lists to Google Groups, which does offer RSS feeds for each group.





groups

Television Network Affiliate Groups to Hold Meetings at 2021 NAB Show




groups

Television Network Affiliate Groups to Hold Meetings at 2022 NAB Show

Washington, D.C. -- The National Association of Broadcasters (NAB) announced today that the affiliate boards of directors of ABC, CBS, FOX Television and NBC will meet in-person during NAB Show, April 23 – 27, 2022, in Las Vegas, Nev.




groups

Television Network Affiliate Groups to Hold Meetings at 2023 NAB Show

Washington, D.C. -- The National Association of Broadcasters (NAB) announced today that the affiliate boards of directors of ABC, CBS, FOX Television and NBC will meet in-person during NAB Show, April 15 – 19, 2023, in Las Vegas, Nev.




groups

Call for Applications to the Youth Contact Groups from Donetsk and Luhansk Regions

Training
Mon, 2016-08-01 (All day) - Sun, 2016-12-25 (All day)
Ukraine
OSCE Project Co-ordinator in Ukraine
OSCE Project Co-ordinator in Ukraine
Eastern Europe
Conflict prevention and resolution

The OSCE Project Co-ordinator in Ukraine (OSCE PCU) is pleased to announce an open call for applications of the young activists from Donetsk and Luhansk regions to join the Youth Contact Group initiative, aimed at promoting inter-regional dialogue and bridge-building between youth. This dialogue initiative was launched by the OSCE Special Monitoring Mission to Ukraine to 2015. Its main task is to equip the youth representatives from different regions of Ukraine with the necessary tools and skills as well as to support implementation of their ideas regarding promotion of dialogue on the today’s issues of concern among Ukrainian youth. The new groups will join efforts with the already selected similar teams in Kyiv, Kharkiv and Lviv.

Profile of a successful applicant

At this opportunity the call targets representatives from young people in Donetsk and Luhansk regions who can demonstrate that they are strongly committed to building sustainable dialogue between youth of their regions and other parts of Ukraine.

Besides that, successful applicants must:

  • Be between the ages of 18 and 28 at the time of implementation of the activities;
  • Demonstrate frequent use of social media;
  • Have a strong interest in the fields of inter-culturalism, peace building, and regional co-operation;
  • Be able to commit to participating in all activities of the initiative

In addition, it is not obligatory but preferable that candidates can:

  • Be familiar with national and international youth policy;
  • Demonstrate previous experience in project implementation;
  • Demonstrate good English language skills.

An equal number of participants will be selected from each of the considered regions. All successful applicants will be notified of the results of the selection process. The OSCE is committed to diversity and inclusion, and encourages qualified female and male candidates from all national, religious, ethnic and social backgrounds to apply.

Costs

No fees apply to any phase of the initiative implementation. All costs related to logistics (boarding, lodging, transport, etc.) will be covered by the OSCE PCU.  

Participants are expected to use their own laptops and smart phones.

How to apply

If you are interested, we strongly encourage you to apply using the links below.

Applications for Donetsk region are now open and you can apply here.

Applications for Luhansk region are now open and you can apply here.

Deadline for applications is 29 July 2016

Related Stories




groups

Roma remain one of most vulnerable groups, continue to face difficult living conditions and discrimination in access to social protection, health, employment and adequate housing, as stated in reports by independent bodies

BELGRADE, 8 April 2016 - On the occasion of International Roma Day, the Delegation of the European Union to Serbia, the United Nations Country Team in Serbia, the OSCE Mission to Serbia and the Council of Europe Office in Belgrade reaffirm our strong commitment to equality and non-discrimination.

Today, the Romani community, Europe's largest ethnic minority, still experiences multiple discrimination and marginalisation in countries throughout Europe, including Serbia.  Roma remain one of the most vulnerable groups; they continue to face difficult living conditions and discrimination in access to social protection, health, employment and adequate housing, as stated in reports by both relevant international mechanisms and independent bodies of the Republic of Serbia.

Thousands of Roma represent the most vulnerable and marginalised among the population of internally displaced, still facing obstacles in accessing rights and durable solutions.

International and European human rights standards clearly provide for equality before the law and prohibit discrimination on all grounds, including ethnicity. The realisation of Roma inclusion will reinforce everyday democracy and the rule of law. It is the only way to reach a society based on the principle of equality of opportunity where everyone has the right to participate and to be heard.

On this day, we therefore call on all relevant stakeholders to pursue with determination 
Roma inclusion policies in Serbia, pursuant to the recent adoption of a new Strategy of Social Inclusion of Roma for the Period from 2015-2025 and the Action Plan for Realization of Rights of National Minorities by the Government of Serbia.

The Delegation of the European Union, the Council of Europe Office in Belgrade, the OSCE Mission to Serbia and the United Nations Country Team in Serbia remain committed to improving the lives of Roma in Serbia and  ensuring that their fundamental rights are respected, and to supporting our Serbian partners in this endeavour.

International Roma Day is celebrated annually on April 8, in commemoration of the 1971 founding of the International Romani Union, the first major international Romani civic initiative.

Statistical information on Roma in Serbia

  • 90% of children in Roma settlements are growing up in poverty. The infant and under-5 mortality rate is two times higher than that of the general population, 15% of Roma children are born with low birth weights, one fifth is malnourished and only 13% are fully immunized.
  • Romani children continue to face discrimination in the education system. Only 6% of children from Roma settlements attend early learning programs, only 64% finish primary school on time, and  only 22% attend secondary school (of whom only 15% are girls).
  • Romani women and girls face multi-sectoral discrimination, as well as heightened barriers of access to services, including services for victims of violence.    Early, arranged marriage remains an issue in some segments of Serbia’s Romani communities, with very destructive consequences for – in particular – the child bride.

For more information & media inquiries please contact:

Aleksandra Stamenkovic, United Nations Country Team Communications Expert, email: aleksandra.stamenkovic@one.un.org, Phone +381 11 415 5314

Nadezda Dramicanin, Delegation of the EU to Serbia Communications Officer, e-mail: Nadezda.DRAMICANIN@eeas.europa.eu, Phone: +381 11 3083 200

Ivana Milatovic, OSCE National Political and Press Affairs Officer, e-mail: ppiu-serbia@osce.org, Phone +381 11 3606 151

Mona Alghaith, Council of Europe Office, Assistant to the Head of Office, e-mail: mona.alghaith@coe.int, Phone. +381 11 71 555 00

 

Related Stories



  • OSCE Mission to Serbia
  • Roma and Sinti issues
  • Tolerance and non-discrimination
  • South-Eastern Europe
  • Press release

groups

Roma remain one of most vulnerable groups, continue to face difficult living conditions and discrimination in access to social protection, health, employment and adequate housing, as stated in reports by independent bodies

BELGRADE, 8 April 2016 - On the occasion of International Roma Day, the Delegation of the European Union to Serbia, the United Nations Country Team in Serbia, the OSCE Mission to Serbia and the Council of Europe Office in Belgrade reaffirm our strong commitment to equality and non-discrimination.

Today, the Romani community, Europe's largest ethnic minority, still experiences multiple discrimination and marginalisation in countries throughout Europe, including Serbia.  Roma remain one of the most vulnerable groups; they continue to face difficult living conditions and discrimination in access to social protection, health, employment and adequate housing, as stated in reports by both relevant international mechanisms and independent bodies of the Republic of Serbia.

Thousands of Roma represent the most vulnerable and marginalised among the population of internally displaced, still facing obstacles in accessing rights and durable solutions.

International and European human rights standards clearly provide for equality before the law and prohibit discrimination on all grounds, including ethnicity. The realisation of Roma inclusion will reinforce everyday democracy and the rule of law. It is the only way to reach a society based on the principle of equality of opportunity where everyone has the right to participate and to be heard.

On this day, we therefore call on all relevant stakeholders to pursue with determination 
Roma inclusion policies in Serbia, pursuant to the recent adoption of a new Strategy of Social Inclusion of Roma for the Period from 2015-2025 and the Action Plan for Realization of Rights of National Minorities by the Government of Serbia.

The Delegation of the European Union, the Council of Europe Office in Belgrade, the OSCE Mission to Serbia and the United Nations Country Team in Serbia remain committed to improving the lives of Roma in Serbia and  ensuring that their fundamental rights are respected, and to supporting our Serbian partners in this endeavour.

International Roma Day is celebrated annually on April 8, in commemoration of the 1971 founding of the International Romani Union, the first major international Romani civic initiative.

Statistical information on Roma in Serbia

  • 90% of children in Roma settlements are growing up in poverty. The infant and under-5 mortality rate is two times higher than that of the general population, 15% of Roma children are born with low birth weights, one fifth is malnourished and only 13% are fully immunized.
  • Romani children continue to face discrimination in the education system. Only 6% of children from Roma settlements attend early learning programs, only 64% finish primary school on time, and  only 22% attend secondary school (of whom only 15% are girls).
  • Romani women and girls face multi-sectoral discrimination, as well as heightened barriers of access to services, including services for victims of violence.    Early, arranged marriage remains an issue in some segments of Serbia’s Romani communities, with very destructive consequences for – in particular – the child bride.

For more information & media inquiries please contact:

Aleksandra Stamenkovic, United Nations Country Team Communications Expert, email: aleksandra.stamenkovic@one.un.org, Phone +381 11 415 5314

Nadezda Dramicanin, Delegation of the EU to Serbia Communications Officer, e-mail: Nadezda.DRAMICANIN@eeas.europa.eu, Phone: +381 11 3083 200

Ivana Milatovic, OSCE National Political and Press Affairs Officer, e-mail: ppiu-serbia@osce.org, Phone +381 11 3606 151

Mona Alghaith, Council of Europe Office, Assistant to the Head of Office, e-mail: mona.alghaith@coe.int, Phone. +381 11 71 555 00

 

Related Stories



  • OSCE Mission to Serbia
  • Roma and Sinti issues
  • Tolerance and non-discrimination
  • South-Eastern Europe
  • Press release

groups

Resolution 54 - (Rev. Geneva, 2022) - Creation of, and assistance to, regional groups

Resolution 54 - (Rev. Geneva, 2022) - Creation of, and assistance to, regional groups




groups

Resolution 99 - (Geneva, 2022) - Consideration of organizational reform of the ITU Telecommunication Standardization Sector study groups

Resolution 99 - (Geneva, 2022) - Consideration of organizational reform of the ITU Telecommunication Standardization Sector study groups





groups

Federal groups, unions brace for what a second Trump term may bring

Some groups congratulated President-elect Trump on his win. Many expressed concerns for the possible return of former Trump policies that would “harm” feds.

The post Federal groups, unions brace for what a second Trump term may bring first appeared on Federal News Network.




groups

European privacy groups challenge facial scan firm Clearview

European privacy groups challenge facial scan firm Clearview




groups

Emails to Microsoft 365 Groups in Outlook syncs only 1 year

We’re using Microsoft 365 Groups instead of Distribution Lists so that a history of these emails are kept in Groups in Outlook as well.

However, I noticed that Groups in Outlook only shows only up to 1 year of emails. When I look at the Microsoft 365 Group in Outlook on the Web, all the emails are shown.

I’ve set Outlook to sync all my emails but it still only shows up to 1 year for Groups. Performing a search doesn’t return any items which are available online either.

How can I make Outlook to sync all emails from the Microsoft 365 Groups?




groups

Kratom regulations shelved in California amid battle between advocacy groups

A California bill that would have imposed regulations on kratom products has been shelved. Kratom is a substance derived from a tree native to Southeast Asia that is sold in the U.S. in powder, capsule and extract form.




groups

Health groups call for suspending state plan on maternal deaths, saying it burdens patients

Maternal health organizations and advocates are urging the California surgeon general to suspend the rollout of a plan aimed at reducing maternal mortality.




groups

Hospice launches Harborne Fundraising Groups to raise vital funds

Birmingham St Mary’s Hospice has unveiled its latest venture aimed at supporting the services on which so many rely.




groups

Emerging Groups

Cumbia Ninja and its album The álbum, as a result of the join between Fox and Sony Music, it will include 17 songs written by the scriptwriter of the series, Andrés Gelós. Mexico City (04/OCT/2013) . The songs more representatives of the series “Cumbia ninja” will can be able acquired by the album that will be produced in the middle of this month. As an advance of this new record production, the songs “Ojos en la espalda” and “Ceviche” can be acquired by a download portal for throughout Latin...




groups

Armed Neighborhood Groups Form In The Absence Of Police Protection

Cesia Baires knocks on the three apartment doors above her restaurant and a neighboring taqueria just before curfew. A woman opens the door. Her two young children are inside. "Remember," she says to them in Spanish. "Same thing as yesterday. I'm going to come check on you. If there's anything you guys need, give us a call right away." Meanwhile, a few men climb through the window and on to the roof to set up semi-automatic weapons as the curfew begins in Minneapolis. It's something Baires never thought she would have to do as a small-business owner, but then she found out these apartments were occupied. "Material things we can replace, that's true," she says. "But there are families up here. These aren't empty buildings." A car drives by boarded-up businesses as it crosses Lake Street in Minneapolis. Volunteers, sometimes armed, are working together to protect homes and businesses. Jim Urquhart for NPR As break-ins and fires raged in the first days of mass protests over the killing of




groups

Jan. 6 Panel Explores Links Between Trump Allies and Extremist Groups

Cassidy Hutchinson, the former White House aide, testified that the former president directed his chief of staff to reach out to Michael Flynn and Roger Stone, who had ties to the Oath Keepers and the Proud Boys.




groups

Brownies & Youth Groups Help Clean Up

Young people from a variety of island groups came together for the Keep Bermuda Beautiful [KBB] Coastal Cleanup, focused on the coasts of Black Bay Beach and Glass Beach. A spokesperson said, “The KBB Coastal Cleanup for 2023 has taken off with a boom. This year the First Devonshire Brownies and the First West Pembroke […]




groups

Musicians: Bands/Groups – Overdue

Troubled Musicians: Bands/Groups (Not open for application) The following fanlistings are scheduled for removal on November 14, 2024. If your fanlisting is listed below, please fix the problem/send in a finished form and reply to the troubles email! Pending Removal – Overdue SR-71; Wallflowers, The



  • Musicians: Bands/Groups

groups

Musicians: Bands/Groups – All

Upcoming Musicians: Bands/Groups D’espairsRay; Kagrra,; Loona; Rentrer en Soi; Rise Against; tripleS Finished Musicians: Bands/Groups SR-71; Wallflowers, The Moved Musicians: Bands/Groups No moved forms have been received since the last update. Closed Musicians: Bands/Groups (Open for application) No closed forms have been received since the last update. Overdue Musicians: Bands/Groups No overdue fanlistings. Overdue: Temporary […]



  • Musicians: Bands/Groups

groups

Songs: Bands/Groups N-Z – Finished

Finished Songs: Bands/Groups N-Z Cover Girl (New Kids On The Block); Games (New Kids On The Block); Hangin’ Tough (New Kids On The Block); I’ll Be Loving You (Forever) (New Kids On The Block); Please Don’t Go Girl (New Kids On The Block); Step by Step (New Kids On The Block)



  • Songs: Bands/Groups N-Z

groups

Improved Photo And Video Posting To Facebook Pages And Groups.

No doubt, media content is very important  when it comes to updating your blogs and social network pages. We totally understand that and constantly improve images and videos processing, either in content feeds or posting campaigns. Today we are glad to introduce one of the latest updates to our Facebook Poster, which improves posting images […]

The post Improved Photo And Video Posting To Facebook Pages And Groups. appeared first on RSSground.com.




groups

“Facebook groups” feeds and posting have been deprecated

We are sorry to inform you that posting to Facebook groups and generating Facebook group feeds is no longer available in RSS Ground. Facebook has deprecated its Groups API and restricted Facebook group access for developers.  Read more about Facebook deprecations and Breaking changes. All posting campaigns that make posts to Facebook groups and RSS […]

The post “Facebook groups” feeds and posting have been deprecated appeared first on RSSground.com.




groups

News24 | US strikes targets to 'degrade the Iranian-backed groups' ability' in Syria

The US military has carried out strikes against targets in Syria in what the United States Central Command (CENTCOM) said was a response to recent attacks on US forces by "Iranian-aligned targets" in the country.




groups

Rational group algebras of generalized strongly monomial groups: Primitive idempotents and units

Gurmeet K. Bakshi, Jyoti Garg and Gabriela Olteanu
Math. Comp. 93 (), 3027-3058.
Abstract, references and article information




groups

Lie groups with all left-invariant semi-Riemannian metrics complete

Ahmed Elshafei, Ana Cristina Ferreira, Miguel Sánchez and Abdelghani Zeghib
Trans. Amer. Math. Soc. 377 (), 5837-5862.
Abstract, references and article information





groups

{alpha}2-Macroglobulin-like protein 1 can conȷugate and inhibit proteases through their hydroxyl groups, because of an enhanced reactivity of its thiol ester [Protein Structure and Folding]

Proteins in the α-macroglobulin (αM) superfamily use thiol esters to form covalent conjugation products upon their proteolytic activation. αM protease inhibitors use theirs to conjugate proteases and preferentially react with primary amines (e.g. on lysine side chains), whereas those of αM complement components C3 and C4B have an increased hydroxyl reactivity that is conveyed by a conserved histidine residue and allows conjugation to cell surface glycans. Human α2-macroglobulin–like protein 1 (A2ML1) is a monomeric protease inhibitor but has the hydroxyl reactivity–conveying histidine residue. Here, we have investigated the role of hydroxyl reactivity in a protease inhibitor by comparing recombinant WT A2ML1 and the A2ML1 H1084N mutant in which this histidine is removed. Both of A2ML1s' thiol esters were reactive toward the amine substrate glycine, but only WT A2ML1 reacted with the hydroxyl substrate glycerol, demonstrating that His-1084 increases the hydroxyl reactivity of A2ML1's thiol ester. Although both A2ML1s conjugated and inhibited thermolysin, His-1084 was required for the conjugation and inhibition of acetylated thermolysin, which lacks primary amines. Using MS, we identified an ester bond formed between a thermolysin serine residue and the A2ML1 thiol ester. These results demonstrate that a histidine-enhanced hydroxyl reactivity can contribute to protease inhibition by an αM protein. His-1084 did not improve A2ML1's protease inhibition at pH 5, indicating that A2ML1's hydroxyl reactivity is not an adaption to its acidic epidermal environment.




groups

DeVos: Give Religious Groups Equal Consideration for Education Grants

The new U.S. Department of Education guidance creates a federal process for individuals and organizations to file complaints under the federal Religious Freedom Restoration Act.