Rockville, MD — Mental health is “just as important for your safety as that harness or anything else that you’re wearing,” Mechanical Contractors Association of America member Ricky Reams says in a new video.

Functional mushroom coffee brand, Four Sigmatic announced that it will debut a new line of organic instant teas. Each tea is infused with functional mushrooms and adaptogens for focus, calm, positive mood, and immune and gut support.

Children's Geographies; 10/01/2021
(AN 152966701); ISSN: 14733285
Academic Search Premier

Children's Geographies; 10/01/2024
(AN 180134754); ISSN: 14733285
Academic Search Premier

Designed by Woogmaster Studio for Walters Wicker, the Avant and Varenna series are inspired by idyllic outdoor living in Italy's picturesque coastlines + villas.

The Exchange presents a special broadcast of Writers on a New England Stage with economist and New York Times columnist Paul Krugman.

In my misquotes page, I documented an erroneous quote by Jerry Bergman in a 1993 article on Nebraska Man in the journal Creation Research Society Quarterly (CRSQ). Bergman has responded, disputing my interpretation, in a new article in the CRSQ: "A misrepresentation by Jim Foley: a correction". Here is my response.

The opioid epidemic in the U.S. is driving a simultaneous epidemic of infectious diseases — including HIV, hepatitis C virus (HCV) and bacterial infections, and sexually transmitted infections — but workforce shortages, stigma, and financial and policy barriers are preventing the integration of opioid use disorder (OUD) and infectious disease services, says a new report from the National Academies of Sciences, Engineering, and Medicine.

The National Academy of Medicine today announced Stephen P. Hinshaw is the recipient of the 2020 Rhoda and Bernard Sarnat International Prize in Mental Health, for basic and applied research on individuals with externalizing disorders, and for efforts to reduce mental illness stigma through youth-based programs and the promotion of humanization.

Would a more robust cybersecurity posture impact premium costs? Does the policy offer legal cover? These are some of the questions organizations should consider when reviewing their cyber insurance options

Two of the producer’s Wings flavors, Buffalo and Korean BBQ, will be offered at more than 100 of the stores across the U.S.

The Georgia Society of Certified Public Accountants (GSCPA) announces new BOD Chair.

Shieldon is an original outdoor cutlery brand produced by the long-established hardware wholesaler "Custom Hardware" in Oem knife.

Expanding Global Low Voltage Infrastructure Services for Smart Building Projects

Local Handyman Services in Washington, DC are Now More Accessible Than Ever

This recognition highlights Wegman's significant contributions to the legal field, outstanding client advocacy, and exceptional personal injury litigation success.

Luvme Hair, a leading brand of high-quality human hair wigs, is excited to present a review of the top 5 most popular 7x6 Lace PartingMax Glueless Wigs from the first half of 2024.

How to Create a Gmail Account for Beginners: Step-by-step guide to set up, secure, and personalize your Gmail account with ease. Perfect for new users.

Genetic tests showed that certain patients were predisposed to brain injuries if they took the drugs. That information remained secret.

Welcome back to another Figma based tutorial, in which we’re going to take a quick look behind the process of creating a phone widget app icon, using nothing more than a couple of basic geometric shapes. So, assuming you already have the software up and running let’s jump straight into it! Tutorial Details: Phone Widget […]

The post How to Create a Phone Widget App Icon in Figma appeared first on Vectips.

Hey, welcome back to another icon tutorial, in which we’re going to explore how to create a messaging app icon in Figma, using nothing more than a couple of basic geometric shapes, that we’re going to adjust here and there. Tutorial Details: Messaging App Icon Program: Figma Difficulty: Beginner Topics Covered: Compositional Construction, Shape Alignment, […]

The post How to Create a Messaging App Icon in Figma appeared first on Vectips.

Fun One Pager showcasing the awesome Figma Plugins by Vijay Verma as game cartridges. Lovely touch with the shooting stars and universe background texture. You can find the Landing Page code on GitHub. ICYMI I interviewed Vijay on the Yo! Podcast. Full Review

The post Can XMail Disrupt Gmail’s Dominance? appeared first on DailyBlogTips.com.

Organizer: Local Government Management Association of BC
Location: Online

Louvre puts the focus on Watteau’s enigmatic “Pierrot” From October 16th, 2024 to  February 3rd,...

Inflation is making prices go up, except not for...sports tickets? So, we set out on a daylong sporting event marathon to learn why.

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From the bugs in our backyards to prehistoric reptiles, animal biology and behavior are full of puzzles and conundrums. On this episode, we hear from experts solving the mysteries of the animal kingdom. Guests include paleontologist Dean Lomax, biochemical engineer Saad Bhamla, herpetologist Gowri Shankar and conservation biologist Patrícia Medici.

TED Radio Hour+ subscribers now get access to bonus episodes, with more ideas from TED speakers and a behind the scenes look with our producers. A Plus subscription also lets you listen to regular episodes (like this one!) without sponsors. Sign-up at: plus.npr.org/ted

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Original broadcast date: July 14, 2023. From the bugs in our backyards to prehistoric reptiles, animal biology and behavior are full of puzzles and conundrums. On this episode, we hear from experts solving the mysteries of the animal kingdom. Guests include paleontologist Dean Lomax, biochemical engineer Saad Bhamla, herpetologist Gowri Shankar and conservation biologist Patrícia Medici.

TED Radio Hour+ subscribers now get access to bonus episodes, with more ideas from TED speakers and a behind the scenes look with our producers. A Plus subscription also lets you listen to regular episodes (like this one!) without sponsors. Sign-up at: plus.npr.org/ted

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Scroll down for how to subscribe, transcript, and more My guest for Episode #519 of the Lean Blog Interviews Podcast is Jarvis Gray, the Managing Director of The Quality Coaching Co. He offers more than 16 years of strategic planning, quality improvement, and operations leadership experience in the healthcare industry.  Through his firm, The Quality Coaching Co., Jarvis and his associates help healthcare organizations foster cultures of system-wide quality improvement by offering customized Lean Six […]

The post Achieving Healthcare Excellence: Insights from Jarvis Gray on Lean Six Sigma and Leadership by Mark Graban appeared first at Lean Blog.

handy reference

Dr P. Freud's Answer - From 'Ask Dr. Pigman Freud' by Hugh M. Kramer. The renowned guinea pig psychotherapist answers questions on guinea pig behavior, psychology and intelligence.

'Ask Dr. Pigman Freud' by Hugh M. Kramer. The renowned guinea pig psychotherapist answers questions on guinea pig behavior, psychology and intelligence.

We are in full-on countdown mode for our yearly education conference, 5Sigma. It’s hard to believe that it is just 10 days away! This year our theme is Launch: The Power of Student Agency. I could not be more excited for our fifth annual conference! Each year we work to include educators who have inspired our...

Aunque Google ofrece 15GB gratuitos, es fácil quedarse sin espacio Leer

דרוש מקדם גוגל ממומן עם ניסיון...

דרושים דרושות אנשים או נשים שי...

Sigma Precision Components Ltd Has A Global Reputation As A Leading Aerospace Manufacturing Company... Ocean Xu, Business Development Manager, Chengdu Shi, Sichuan Sheng, China

We have a friend from Flipora, which we did not know we had... Oh sorry our mistake, iyaloo27@gmail.com is not our friend, he/she is a spammer and spammers are our enemy.

But the most dangerous attackers of American democracy aren’t the Russians or the Chinese. They are the leaders of the Republican Party.

New on NextDoorStudios, an ASGMax site: Colt Spence would do anything to just relax today. He’s been beyond stressed out from work and his wife won’t stop calling him incessantly just to check in and see how he’s doing. Finally thinking he has some alone time, he ends up getting a surprise visitor when Andrew... View Article

The post ASGMax | NextDoorStudios: Andrew Delta and Colt Spence – “No Time to Relax” appeared first on QueerClick.

Described by some as an "enigma", Mrs Trump is expected to return to her White House duties "on her own terms".

A. V. Domrina
Trans. Moscow Math. Soc. 83 (), 201-215.
Abstract, references and article information

Genetic mutations related to ALS, a progressive neurological disease, have been discovered in the gene encoding σ-1 receptor (σ1R). We previously reported that σ1RE102Q elicits toxicity in cells. The σ1R forms oligomeric states that are regulated by ligands. Nevertheless, little is known about the effect of ALS-related mutations on oligomer formation. Here, we transfected NSC-34 cells, a motor neuronal cell line, and HEK293T cells with σ1R-mCherry (mCh), σ1RE102Q-mCh, or nontagged forms to investigate detergent solubility and subcellular distribution using immunocytochemistry and fluorescence recovery after photobleaching. The oligomeric state was determined using crosslinking procedure. σ1Rs were soluble to detergents, whereas the mutants accumulated in the insoluble fraction. Within the soluble fraction, peak distribution of mutants appeared in higher sucrose density fractions. Mutants formed intracellular aggregates that were co-stained with p62, ubiquitin, and phosphorylated pancreatic eukaryotic translation initiation factor-2-α kinase in NSC-34 cells but not in HEK293T cells. The aggregates had significantly lower recovery in fluorescence recovery after photobleaching. Acute treatment with σ1R agonist SA4503 failed to improve recovery, whereas prolonged treatment for 48 h significantly decreased σ1RE102Q-mCh insolubility and inhibited apoptosis. Whereas σ1R-mCh formed monomers and dimers, σ1RE102Q-mCh also formed trimers and tetramers. SA4503 reduced accumulation of the four types in the insoluble fraction and increased monomers in the soluble fraction. The σ1RE102Q insolubility was diminished by σ1R-mCh co-expression. These results suggest that the agonist and WT σ1R modify the detergent insolubility, toxicity, and oligomeric state of σ1RE102Q, which may lead to promising new treatments for σ1R-related ALS.