On this week's edition of The Watchman, we're joined by Lt. Gen. (Ret.) Jerry Boykin of the Family Research Council and Kamal Saleem of Koome Ministries to discuss their thrilling new novel about radical Islam, "The Coalition." Click on the ... ...

On this week's edition of The Watchman, we sit down with Michael Pregent of Veterans Against the Deal to analyze Iran's threats against Israel and the United States. We also examine ISIS's dreams of conquering Rome.

On this week's edition of The Watchman, we look ahead to 2016 and the major stories to watch for, including ISIS, Iran, Russia in the Middle East, homegrown jihad and more.

On this week's edition of The Watchman, we examine the Islamic terrorist attack in San Bernardino and what's next in ISIS's war against America.

The Watchman: - January 19, 2016

On this week's edition of The Watchman, we interview Rabbi Yechiel Eckstein, founder of the International Fellowship of Christians and Jews, about the new authorized biography on his life and work, "The Bridge Builder." We also recap ...

Simpson Strong-Tie has introduced Quik Drive Project Pro, a screw-driving tool that installs on nearly any cordless drill or driver and provides the speed and convenience of auto-feed fastening for a variety of projects without the larger investment of a full-service tool.

Milwaukee Tool continues its commitment to disruptive innovation, expanding its PACKOUT Modular Storage System with eight new PACKOUT Toolbox Attachments. These new solutions securely lock onto the PACKOUT system’s metal-reinforced corners, allowing professionals to carry more and quickly access tools, parts and materials, enhancing job site productivity.

Keeping stucco and EIFS secured to surfaces.

The Gypsum Association announced that ASTM International has recognized GA director of codes, standards and research Michael Schmeida, MSc, LEED AP, with an ASTM Award of Merit and the title of Fellow.

The ANSI-approved standard aligns with the enterprise security risk management (ESRM) approach, serving as a tool to safeguard cannabis organizations and their assets by taking a holistic perspective.

Itasca, IL — Improving methods of tracking musculoskeletal disorders, continuously monitoring and assessing physical risk factors, and sharing best practices can help workplace MSD prevention programs have real impact.

Fishman Flooring’s new president Shane Richmond discusses the benefit of Employee Stock Ownership Plans, succession planning and the future of flooring distribution. 

Children's Geographies; 04/01/2023
(AN 163915531); ISSN: 14733285
Academic Search Premier

Children's Geographies; 10/01/2023
(AN 173035616); ISSN: 14733285
Academic Search Premier

Children's Geographies; 08/03/2024
(AN 178803291); ISSN: 14733285
Academic Search Premier

If you consider yourself creative, innovative, a problem solver and you would like to influence and contribute to defining the next-generation CPUs that will be used in billions of devices worldwide, you will enjoy working and developing your professional career with us.

We are looking for graduate engineers who are passionate about understanding the workloads of the future to join our CPU benchmarking team.

Our benchmarking team is in charge of interacting with product managers, partners, CPU leads and performance modelling leads to understand the most relevant applications industry will use in the future and help to characterise and reproduce them on cutting-edge environments ranging from simulation to emulation or FPGA. The team is also responsible for investigating novel techniques to facilitate the utilisation of benchmarks that are relentlessly growing in complexity and make them suitable for the exploration of next generation CPU cores and systems.

As part of the CPU team, we will collaborate to innovate and find engineering solutions to the challenges of tomorrow in areas like IoT, automotive, servers or mobile; we will make devices smarter and more useful to society. Your contributions will help to build new technology that will influence the lives of billions of people!

Graduate on CPU Benchmark Role at Arm

We have exciting opportunities in the CPU group, where you will be part of a highly motivated team that helps define new generations of mainstream processors.

You will have real responsibilities from day one and you will get support and mentorship from specialists that will help you succeed and develop your career. Through teamwork, training, and dedication to personal development, we ensure that every graduate matures to become a specialist in the field.

You will work in a multi-site, multi-cultural environment and will have the opportunity to work on different projects.

What will your role be?

• You will contribute to the definition of the next generation of Arm’s IP products, identifying and enabling new benchmarks, and proposing new insights on methodologies that could improve current practice in benchmark characterisation and simulation.
• Together with marketing, technical leads, modelling leads and partners we will align on applications that will represent market requirements for future products.
• You will propose, develop and maintain innovative ways of making relevant applications and benchmarks suitable for sophisticated simulation platforms.
• You will collaborate with technical leads, performance modelling engineers and designers while doing performance analysis on existing and future designs.
• Explore new methodologies and novel software techniques that will improve modelling efficiency.

AI-Media - the global provider of audiovisual encoding technology and AI-driven transcription and translation solutions, and Speechmatics - the provider of speech recognition technology, have announced a strategic expansion of their multi-year partnership to deliver new and better AI-driven products to market.

[Science] :
Two U.S. experts who inspected North Korea’s uranium enrichment facility at the Yongbyon nuclear complex in 2010 have analyzed recent images of a similar facility in the North and pointed out differences.  Stanford University professor emeritus Siegfried Hecker and Robert Carlin, a scholar at the ...

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Stimulated by informal conversations at the XVII International Small Angle Scattering (SAS) conference (Traverse City, 2017), an international team of experts undertook a round-robin exercise to produce a large dataset from proteins under standard solution conditions. These data were used to generate consensus SAS profiles for xylose isomerase, urate oxidase, xylanase, lysozyme and ribonuclease A. Here, we apply a new protocol using maximum likelihood with a larger number of the contributed datasets to generate improved consensus profiles. We investigate the fits of these profiles to predicted profiles from atomic coordinates that incorporate different models to account for the contribution to the scattering of water molecules of hydration surrounding proteins in solution. Programs using an implicit, shell-type hydration layer generally optimize fits to experimental data with the aid of two parameters that adjust the volume of the bulk solvent excluded by the protein and the contrast of the hydration layer. For these models, we found the error-weighted residual differences between the model and the experiment generally reflected the subsidiary maxima and minima in the consensus profiles that are determined by the size of the protein plus the hydration layer. By comparison, all-atom solute and solvent molecular dynamics (MD) simulations are without the benefit of adjustable parameters and, nonetheless, they yielded at least equally good fits with residual differences that are less reflective of the structure in the consensus profile. Further, where MD simulations accounted for the precise solvent composition of the experiment, specifically the inclusion of ions, the modelled radius of gyration values were significantly closer to the experiment. The power of adjustable parameters to mask real differences between a model and the structure present in solution is demonstrated by the results for the conformationally dynamic ribonuclease A and calculations with pseudo-experimental data. This study shows that, while methods invoking an implicit hydration layer have the unequivocal advantage of speed, care is needed to understand the influence of the adjustable parameters. All-atom solute and solvent MD simulations are slower but are less susceptible to false positives, and can account for thermal fluctuations in atomic positions, and more accurately represent the water molecules of hydration that contribute to the scattering profile.

Conformational heterogeneity of biological macromolecules is a challenge in single-particle averaging (SPA). Current standard practice is to employ classification and filtering methods that may allow a discrete number of conformational states to be reconstructed. However, the conformation space accessible to these molecules is continuous and, therefore, explored incompletely by a small number of discrete classes. Recently developed heterogeneous reconstruction algorithms (HRAs) to analyse continuous heterogeneity rely on machine-learning methods that employ low-dimensional latent space representations. The non-linear nature of many of these methods poses a challenge to their validation and interpretation and to identifying functionally relevant conformational trajectories. These methods would benefit from in-depth benchmarking using high-quality synthetic data and concomitant ground truth information. We present a framework for the simulation and subsequent analysis with respect to the ground truth of cryo-EM micrographs containing particles whose conformational heterogeneity is sourced from molecular dynamics simulations. These synthetic data can be processed as if they were experimental data, allowing aspects of standard SPA workflows as well as heterogeneous reconstruction methods to be compared with known ground truth using available utilities. The simulation and analysis of several such datasets are demonstrated and an initial investigation into HRAs is presented.

Conformational change mediates the biological functions of macromolecules. Crystallographic measurements can map these changes with extraordinary sensitivity as a function of mutations, ligands and time. A popular method for detecting structural differences between crystallographic data sets is the isomorphous difference map. These maps combine the phases of a chosen reference state with the observed changes in structure factor amplitudes to yield a map of changes in electron density. Such maps are much more sensitive to conformational change than structure refinement is, and are unbiased in the sense that observed differences do not depend on refinement of the perturbed state. However, even modest changes in unit-cell properties can render isomorphous difference maps useless. This is unnecessary. Described here is a generalized procedure for calculating observed difference maps that retains the high sensitivity to conformational change and avoids structure refinement of the perturbed state. This procedure is implemented in an open-source Python package, MatchMaps, that can be run in any software environment supporting PHENIX [Liebschner et al. (2019). Acta Cryst. D75, 861–877] and CCP4 [Agirre et al. (2023). Acta Cryst. D79, 449–461]. Worked examples show that MatchMaps `rescues' observed difference electron-density maps for poorly isomorphous crystals, corrects artifacts in nominally isomorphous difference maps, and extends to detecting differences across copies within the asymmetric unit or across altogether different crystal forms.

At the tops of many mountains and along numerous roads across the USA are small brass disks called benchmarks.  These survey points are critical for mapping the landscape, determining boundaries, and documenting changes, and there are hundreds of them in Yellowstone National Park!

The new Eric and Wendy Schmidt Awards for Excellence in Science Communication aim to recognize and develop excellence in science communication by research scientists and by early career, local, and freelance science journalists. The program will provide winners with cash awards as well as training and resources to further expand their communications skills.

The 24 inaugural recipients of the Eric and Wendy Schmidt Awards for Excellence in Science Communication have been announced. Given by the National Academies in partnership with Schmidt Futures, the awards recognize science journalists and research scientists who have developed creative, original work about issues and advances in science, engineering, and medicine.

Submissions are now being accepted for the 2023 Eric and Wendy Schmidt Awards for Excellence in Science Communications, which honor top science communicators, journalists, and research scientists who have developed creative, original work to communicate issues and advances in science, engineering, and medicine for the general public.

He has been in the spotlight in recent weeks after the launch of the first investigations under a new EU law into X (formerly Twitter), Facebook owner Meta and TikTok over the spread of false information and hate speech following the Hamas-Israel conflict.

The new AI-powered Project Market Scanner (PMS) engine helped the developers increase their reach by 65% and the lead-to-impression ratio on its platform by 80%.

The Benchmix 10 includes the patented Admix Rotosolver high shear mix head, engineered for high efficacy of wetting out and dispersing powders, eliminating agglomerates, and creating homogenous mixtures and emulsions. 

The cost tracking of production is a never ending task for those responsible for recording, compiling and analyzing raw and packaging materials costs to determine realistic, accurate and beneficial data upon which to base selling prices in complicated and diverse markets.

Bannochmoor Estate Unveils Vision to Transform Scottish Heritage into a Global, Interactive Experience.

Stephen A. Grochmal, MD, serves as a medical director at Integrative Gynecology LLC

John M. Richmond has developed major innovations in the field of gold recovery across a career of more than 40 years

Aurelie Schmitt is honored for her contributions as the head of finance at Philips

How to Select and Use the Proper Massage Gun Head Attachment for Different Body Parts and Needs

Safr Care welcomes Chris Schmaltz to its advisory board to help provide non-emergency medical transportation to the patients of value-based care providers.

Ron Gordon and his team are dedicated to preserving the excellence of Rolex timepieces. All Rolex service is performed in-house, ensuring the highest quality craftsmanship.

The company now offers red dot holsters and light-bearing holsters for over 2,000 handgun models.

Tune into Channel 8 ABC Dallas for 'Dating I Do's and Don'ts' by renowned matchmaker Katy Clark, your ultimate guide to revitalizing your love life, whether married or single.

GLP-1 medications have a huge potential to fix the obesity epidemic!

Breanna Hammerschmidt thrives as a graphic designer and photographer within the marketing industry

"I commend the governor for doing the right thing and standing up for the victims and their families," Hochman said.

This is the eighth year in a row Daniel Schmitt & Co. has supported the nonprofit.

Rare vehicles include 1970 Porsche 914/6 2.0 Targa and 1990 Porsche 911 Carrera 2 sunroof coupe

The vehicles are investment grade and available to the public.

Mike Fabbri just likes to make people happy. If he can get them into a home as their buyer agent or guide them to a closing as their seller agent, it’s win-win. But it’s his self-professed hobby as a matchmaker that gives him a unique identity. And on the occasion when he doubles up, helping…

The post Meet the Matchmaking Agent Who Helps People Find Homes, Love or Both appeared first on RISMedia.

Unless you're famous - or want to be - you might not think of yourself as a brand. But whether you're in a meeting or on social media, interviewing for a job or asking for a promotion, the way you carry yourself conveys a certain image to the people around you. Jill Avery studies marketing and is a senior lecturer at Harvard Business School, and Rachel Greenwald is a professional matchmaker and dating coach. Together, they explain why a strong personal brand is important for professional success. They walk us through how to think about reputation, identify core values, and project our authentic selves. Avery and Greenwald wrote the HBR article “A New Approach to Building Your Personal Brand.”