agents

In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP

RSC Med. Chem., 2024, 15,3674-3694
DOI: 10.1039/D4MD00580E, Research Article
Jinhua Ning, Nini Zhan, Zhanpan Wu, Yuzhe Li, Die Zhang, Yadian Shi, Yingxun Zhou, Chuan-Huizi Chen, Wenbin Jin
Oridonin analogue 11a showed significant antitumor efficacy in vitro via cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP accumulation, meanwhile, displayed much more stable than oridonin in human plasma.
The content of this RSS Feed (c) The Royal Society of Chemistry




agents

Synthesis and evaluation of photoaffinity labeling reagents for identifying binding sites of sulfated neurosteroids on NMDA and GABAA receptors

RSC Adv., 2024, 14,36352-36369
DOI: 10.1039/D4RA07074G, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Mingxing Qian, Yuanjian Xu, Hong-Jin Shu, Zi-Wei Chen, Lei Wang, Charles F. Zorumski, Alex S. Evers, Steven Mennerick, Douglas F. Covey
Photoaffinity labels (PALs) for sulfated steroid binding sites on GABAA and NMDA receptors. The PALs have varying profiles of positive and negative modulatory (PAM and NAM) actions.
The content of this RSS Feed (c) The Royal Society of Chemistry




agents

6 Ways AI Empowers Contact Center Agents

Do you need to improve agent performance at your contact center? Here’s 6 ways AI tools can boost agent productivity, improving customer satisfaction in turn.

Continue reading...




agents

Off-Broadway Comedy 'Craving for Travel' Showcases Travel Agents Trying to do the Impossible

Filed under: , ,

Facebook/Craving for Travel

Joanne and Gary, rival travel agents compete for their industry's top honor, the Globel Prize, while trying to address their clients' impossible demands in an Off-Broadway comedy that debuts this week, "Craving for Travel."

The 85-minute, two-actor, 30-character comedy was commissioned and produced by Jim Strong, president of the Dallas-based Strong Travel Services travel agency.

"Travel agents are always asked to do the impossible, and this play shows how that is done, from finding the impossible rooms to making dreams come true," Strong told the "Dallas Morning News." "I decided to bring it to life on stage as a comedy in New York."

From "Craving for Travel's" press release:

With their reputations on the line, travel agents Joanne and Gary will tackle any request, no matter how impossible, and any client, no matter how unreasonable. Full of overzealous travelers, overbooked flights, and hoteliers who are just over it, Craving for Travel reminds us why we travel-and everything that can happen when we do.

"Craving for Travel" opens Thursday at the Peter J. Sharp Theater, where it'll run through Feb. 9. Tickets are $32.50 and $49. They can be purchased at CravingForTravel.com, 212-279-4200 or the Ticket Central Box Office (416 W. 42nd St., 12-8 p.m. daily). More than half of the shows are already sold out.

Continue reading Off-Broadway Comedy 'Craving for Travel' Showcases Travel Agents Trying to do the Impossible

Off-Broadway Comedy 'Craving for Travel' Showcases Travel Agents Trying to do the Impossible originally appeared on Gadling on Tue, 07 Jan 2014 10:19:00 EST. Please see our terms for use of feeds.

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agents

Why agents are the next step in transforming your business with gen AI

The rise of generative AI (gen AI) and ChatGPT has brought large language models (LLMs) to the forefront of technological innovation. Unlike traditional AI, these LLMs can process and generate language in a way that mimics human reasoning. Businesses are leveraging this technology in various ways, including content generation, customer service interactions, and document summarization. Gen AI offers businesses a chance to streamline operations and improve efficiency. However, LLMs are not universally…




agents

Registered Agents

Have you ever wanted to know what a registered is? Have you ever wondered what a registered agent does? Have you ever wanted to know if you could be your…




agents

Languedoc Real Estate and Property Agents

If you are buying or selling you will probably want to find a real estate agent.
Here's a directory of languedoc real estate agents by town or region.

- The Survival Guide /




agents

Special Agents of Christ, Operation 1

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Operation 1: Daily Prayer.




agents

Special Agents of Christ, Operation 2

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Operation 2: Prayers in Time of Trouble.




agents

Special Agents of Christ, Operation 3

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Operation 3: Prayers of Thanks.




agents

Special Agents of Christ, Operation 4

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Operation 4: Prayers for Family, Friends, and Enemies.




agents

Special Agents of Christ, Operation 5

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Operation 5: Prayers for the Dead




agents

Special Agents of Christ, Operation 6

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Operation 6: Preparation for Confession.




agents

Special Agents of Christ, Operation 7

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Operation 7: Praying with the Saints and Angels .




agents

Special Agents of Christ, Operation 8

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Operation 8: Pray like a King.




agents

Special Agents of Christ, Drill 1

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Drill One: The Five Training Targets, the Five Senses.




agents

Special Agents of Christ, Drill 3

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Drill 3: Sore feet for the Kingdom – The Liturgy.




agents

Special Agents of Christ, Drill 4

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Drill 4: Live like an Agent.




agents

Special Agents of Christ, Drill 2

Special Agents of Christ: A Prayer Book for Young Orthodox Saints by Annalisa Boyd (Conciliar Press, 2012). Drill 2: Agent Attire - Priests and why they wear what they wear.




agents

Special Agents of Christ

Bobby interviews Annalisa Boyd, the author of the new Conciliar Press book Special Agents of Christ: A Prayer Book for Young Orthodox Saints.




agents

Principals, Agents and Prisoners: An Economical Perspective on Information Systems Development Practice




agents

Software Agents for Managing Learning Plans




agents

Transaction Flow in Card Payment Systems Using Mobile Agents




agents

Modalities of Using Learning Objects for Intelligent Agents in Learning




agents

Towards the Automatic Generation of Virtual Presenter Agents





agents

DOT goes ‘Back to Basics’ for drug and alcohol testing agents

Washington — The Department of Transportation has created “reminders” that highlight common issues service agents encounter during the drug and alcohol testing process.




agents

'She doesn't have to get in the car ... ': exploring social workers' understandings of sexually exploited girls as agents and choice-makers.

Children's Geographies; 10/01/2022
(AN 159948769); ISSN: 14733285
Academic Search Premier




agents

Iranian agents plotted to murder Trump, unsealed DOJ charges reveal

The details of an unsealed Iranian murder-for-hire plot to kill President-elect Donald Trump raise questions about how the current administration will act, as President Joe Biden previously warned Iran that the United States would consider its targeting of the Republican nominee as an "act of war." 




agents

Research Needed to Reduce Scientific Uncertainty About Effects of Hormonally Active Agents in the Environment

Although there is evidence of harmful health and ecological effects associated with exposure to high doses of chemicals known as hormonally active agents – or endocrine disrupters – little is understood about the harm posed by exposure to the substances at low concentrations, such as those that typically exist in the environment, says a new report from a National Research Council committee.




agents

Rise of AI agents is imminent: Godard Abel, Global CEO, G2.com

Organizations can tap into $200 billion AI infrastructure built by Amazon, Microsoft, Google




agents

Blue California launches clean-label food-grade whitening agents

Blue California has launched novel food-grade whitening agents as a clean-label alternative to replacing potential health risk white colorant titanium dioxide.




agents

Agents of change

Are you part of the problem, or part of the solution? If you don't automatically align with the solution end of that equation, you might want to think about your overall messaging to consumers, and to the industry overall.




agents

Supply-chain diversity of leavening agents helps grow bakery product appeal

To successfully bake products requires an astute blend of art and science. A fundamental ingredient in the baking process is the leavening agent. Leavening contributes essential sensory characteristics to bakery products.




agents

Clean-label leavening agents appeal to consumers

Leavening is a fundamental ingredient category in baking that performs some serious heavy lifting. Leavening agents help create the textural quality in many baked goods.




agents

Functional, health trends call for masking agents

Current trends for health-and-wellness, plant-based, reduced-sugar and functional beverages, for example, easily can affect the taste, mouthfeel and overall beverage experience. Thus, beverage formulators engage masking ingredients to fight off any unwanted effects.




agents

Agent Live 360 Introduces A New CMS-Client Management System For Sports Agents

Answering The Huge Demands For The Sports Management Marketplace




agents

ADAP Advocacy Association Circulates HIV Long-Acting Agents Policy, via its Newly Minted ADAP Injectables Advisory Committee

The Future is Now – Welcome to the Age of Injectables




agents

Introducing the Best Pay Per Head Service for Sports Betting Agents:

Payperhead.co




agents

5 No-Cost Learning Resources for LLM Agents

Curious about LLM agents? Here’s a list of free courses, guides, and blogs that make it easy to start learning and stay updated.




agents

Unlocking Success: The Power of Follow-Up In Recruiting Real Estate Agents

In the competitive realm of real estate, recruiting agents is a pivotal task, and the fortune often lies in the art of follow-up. Changing brokerages is a significant decision, and acknowledging the weight of this transition can make all the difference.  Culture beyond words Show don’t just tell. Use the follow-up process to immerse potential…

The post Unlocking Success: The Power of Follow-Up In Recruiting Real Estate Agents appeared first on RISMedia.




agents

Spot AI debuts Video AI Agents, transforming camera footage into a proactive, valuable data source

By infusing cameras with advanced AI technology, Video AI Agents enable cameras to identify, reason, and trigger responses to real-life incidents without requiring human intervention




agents

Conversational Agents and AI Transformation: Q&A with Rob Ryan, Head of Business Value and Thought Leadership, Workgrid

AI adoption as a whole is very fragmented depending on the organization, depending on the market business vertical. The real game changer of AI is embedding into those deeper systems of operations, not just surface level use cases of generate a blog, generate news. AI should be evolving with your organization, your culture, and your appetite for risk. That's where Workgrid certainly comes in. Workgrid's platform is built to meet you wherever you happen to be on that journey.




agents

Dolphins give big money to nose tackle, bring in prospects with local ties among undrafted free agents

The Miami Dolphins immediately got to work adding undrafted free agents to their rookie class upon completion of the NFL draft Saturday night.




agents

AI Agents Market to Be Worth $47.1 Billion by 2030

MarketsandMarkets projects 44.8 percent CAGR for the AI agent technology market over the next six years.




agents

Supernormal Launches Voice Agents

Supernormal's Voice Agents help businesses build conversational AI assistants.




agents

2 border agents are fired for offensive Facebook posts

Congressional investigators say two Border Patrol agents were fired from among 60 found to have committed misconduct for participating in a private Facebook group that mocked migrants and lawmakers

The post 2 border agents are fired for offensive Facebook posts first appeared on Federal News Network.




agents

Biomedical imaging : the chemistry of labels, probes, and contrast agents

Location: Sciences Library Library- RC78.7.D53B56 2012




agents

Ind Seasonal Aircraft Deicing Agents

Indianapolis, IN United States Description Looking For Extra Cash? Part Time Seasonal Opportunities Available Now!! Menzies Aviation is looking for Part Time employees to join our Deicing team at Indianapolis Airport (IND). These positions are seasonal from October through Spring (April/May). Training planned to begin in September. + 1st and 2nd Shift schedules with weekend availability needed. + Competitive Wages $20/hr + No Experience Needed – Paid Training Provided + Uniforms Provided w/ Winter Gear + Opportunities for growth and advancement Essential Duties and Responsibilities include the following. Other duties May be assigned. + Responsible for checking aircraft for leading edge ice and frost. + Application of Deice Fluid Type 1 or Type 4 to aircraft wings fuselage and tail. + Responsible for driving large heavy vehi




agents

Pt Ramp Agents {eisenhower National Airport}

Wichita, KS United States Description Great News! Menzies Aviation is seeking Part Time Ramp Agents!!! Are you a team player? Do you enjoy working in a team environment? Join Menzies Aviation and be part of our family!!! Benefits: + Full Benefits PTO DENTAL MEDICAL VISION 401K + Paid Training + Discount Programs + Flight Benefits!!! Why Choose Menzies Aviation: + Full Benefits: paid time off and health insurance for all full time employees + Professional growth: Menzies offer career growth opportunities. + Team environment: a fun fast paced and supportive company culture + Equal opportunity employer: Menzies Aviation is an equal opportunity employer and does not discriminate on the basis of race national origin gender gender identity sexual orientation protected veteran status disability age or other legally What Youll Do: Unloading and loa