Chief executives of the nation's leading companies like Samsung Electronics, SK Hynix, and LG Display have made a request to the government to relieve the problem of labor shortage in the area of semiconductor and display. Kwon Oh-hyun, vice chairman of Samsung Electronics, said on September 18 in a discussion session held in Kensington Hotel in Seoul's Yoido presided over by Minister of Trade, Industry, and Energy Baek Woon-gyu, "Skilled workers are in short supply in fast-growing industries...

Crystal Palace went into the second leg of the play-off semi-final against Brighton & Hove Albion without the Championship's top scorer, Glenn Murray. Murray had found the back of the net 30 times...

Sixteen are from Unguja while 13 are from Pemba, all Tanzanians.

The U.S. needs a more expansive strategy to maintain its lead in this field, and that means working closely with its allies, especially Japan.

'The pandemic continues to unleash a tsunami of hate and xenophobia, scapegoating and scare-mongering'

In the Halle attack, two people were killed near the synagogue when the alleged gunman could not enter the building.

SST Announces Qualification of Smartbit™ OTP NVM Technology for ON Semiconductor’s 110 nm CMOS Process

Rep. McSally Visits Microchip Executives to Discuss Semiconductor Supply Chain Resilience in the U.S. Amid Defense Industrial Base Report Findings

It’s not just about the sperm: the semen of male fish carries unidentified substances that influence how quickly the offspring develop and even how well they can swim

ABSTRACT

A bioinformatics approach was employed to identify transcriptome alterations in the peripheral blood mononuclear cells of well-characterized human subjects who were diagnosed with early disseminated Lyme disease (LD) based on stringent microbiological and clinical criteria. Transcriptomes were assessed at the time of presentation and also at approximately 1 month (early convalescence) and 6 months (late convalescence) after initiation of an appropriate antibiotic regimen. Comparative transcriptomics identified 335 transcripts, representing 233 unique genes, with significant alterations of at least 2-fold expression in acute- or convalescent-phase blood samples from LD subjects relative to healthy donors. Acute-phase blood samples from LD subjects had the largest number of differentially expressed transcripts (187 induced, 54 repressed). This transcriptional profile, which was dominated by interferon-regulated genes, was sustained during early convalescence. 6 months after antibiotic treatment the transcriptome of LD subjects was indistinguishable from that of healthy controls based on two separate methods of analysis. Return of the LD expression profile to levels found in control subjects was concordant with disease outcome; 82% of subjects with LD experienced at least one symptom at the baseline visit compared to 43% at the early convalescence time point and only a single patient (9%) at the 6-month convalescence time point. Using the random forest machine learning algorithm, we developed an efficient computational framework to identify sets of 20 classifier genes that discriminated LD from other bacterial and viral infections. These novel LD biomarkers not only differentiated subjects with acute disseminated LD from healthy controls with 96% accuracy but also distinguished between subjects with acute and resolved (late convalescent) disease with 97% accuracy.

IMPORTANCE Lyme disease (LD), caused by Borrelia burgdorferi, is the most common tick-borne infectious disease in the United States. We examined gene expression patterns in the blood of individuals with early disseminated LD at the time of diagnosis (acute) and also at approximately 1 month and 6 months following antibiotic treatment. A distinct acute LD profile was observed that was sustained during early convalescence (1 month) but returned to control levels 6 months after treatment. Using a computer learning algorithm, we identified sets of 20 classifier genes that discriminate LD from other bacterial and viral infections. In addition, these novel LD biomarkers are highly accurate in distinguishing patients with acute LD from healthy subjects and in discriminating between individuals with active and resolved infection. This computational approach offers the potential for more accurate diagnosis of early disseminated Lyme disease. It may also allow improved monitoring of treatment efficacy and disease resolution.

A 4-year surveillance of carbapenem-resistant Acinetobacter spp. isolates in Argentina identified 40 strains carrying bla_NDM-1. Genome sequencing revealed that most were Acinetobacter baumannii, whereas seven represented other Acinetobacter spp. The A. baumannii genomes were closely related, suggesting recent spread. bla_NDM-1 was located in the chromosome of A. baumannii strains and on a plasmid in non-A. baumannii strains. A resistance gene island carrying bla_PER-7 and other resistance determinants was found on a plasmid in some A. baumannii strains.

थैलेसीमिया मुख्यत: एक जेनेटिक यानी अनुवांशिक बीमारी है जो माता-पिता से उनके बच्चों में होती है। इस बीमारी में बच्चों में खून की कमी होने लगती है, जो कि सेहत के लिए बहुत हानिकारक होता है।

While the present-day Martian surface is generally dry and cold, its sedimentary rocks contain compelling evidence for the former presence of liquid water. According to a new analysis of orbital images of 3.7-billion-year-old sedimentary layers at Izola mensa, an outcrop in the northwestern rim of the Hellas impact crater on Mars, deep rivers were active [...]

Tournament favourites Australia advanced into the semi-finals of the men's hockey World Cup on Monday after they beat Pakistan 2-1 in a pulsating match to finish top of Pool B.

Alberta's police watchdog have released new details about an armed confrontation that left one person dead and a police officer seriously injured.

Jeremy Corbyn's allies have been accused of using a report to "smear whistleblowers" and "discredit allegations" of anti-Semitism in the Labour Party during his tenure.

The move comes after revelations that a party investigation claimed to have found "no evidence" of anti-Semitism complaints being handled differently to other forms of complaint.

Sir Keir Starmer has called for Labour's inquiry into a leaked anti-Semitism dossier to be concluded in a "matter of months", ahead of a meeting of the party's ruling National Executive Committee.

Hit Netflix show expected to return in 2021

Proposed changes to the Champions League could 'end the Premier League top-four race' with qualification restricted, according to reports.

Little Richard, the wild singer/pianist/songwriter who was one of rock ‘n roll’s pioneers, has died at age 87. His death was confirmed by his son, but the cause was not given. Little Richard’s catalog of hits is still performed by many bar bands to this day, and the songs were recorded by such acts as […]

Mass shooters appear to injure and kill more people when the use semiautomatic rifles instead of handguns, other types of rifles, or shotguns, according to a new analysis in the Journal of The American Medical Association. But the research has significant limitations.

"Helping foreign countries improve their criminal justice systems so they can cooperate more effectively with us and with their neighbors in real time is an important aspect of this department’s mission."

The Department has reached a proposed settlement with Microsemi Corporation that requires the company to divest all of the assets that it acquired from Semicoa Inc. on July 14, 2008. The Department said that without this divestiture, there would be little or no competition in the development, manufacture and sale of certain semiconductor devices used in military and space programs essential to the security of the United States.

"I know that you are dedicated to your clients, and to defending them as vigorously as you can, while at the same time recognizing the importance of criminal prosecution to society. And in representing clients who would not have the means to defend themselves without you, you are essential to our adversary system."

“The international expansion and increased violence of transnational criminal networks pose a significant threat to the United States."

Peter Picone, 40, of Methuen, Mass., has been charged with importing counterfeit semiconductors from China for sale in the United States.

The Department of Justice announced that this morning John W. Ng, 58, of Albuquerque, N.M., made his initial appearance in federal court on a criminal complaint charging him with a hate crime offense.

The group of Yosemite Hospitality workers were told this week layoffs require them to leave Yosemite by May 21.

We hosted a Development Seminar on “Unemployment and domestic violence — new evidence from administrative data” with Dr. Sonia Bhalotra, Professor of Economics at University of Essex. Abstract: This paper provides possibly the first causal estimates of how individual job loss among men influences the risk of intimate partner violence (IPV), distinguishing threats from assaults. The authors find…

We hosted a Development Seminar on “Unemployment and domestic violence — new evidence from administrative data” with Dr. Sonia Bhalotra, Professor of Economics at University of Essex. Abstract: This paper provides possibly the first causal estimates of how individual job loss among men influences the risk of intimate partner violence (IPV), distinguishing threats from assaults. The authors find…

Fossil fuel divestment is a moral issue. Religious institutions appear to be taking a stand.

Take one of the world's most beautiful places, add dappled sunlight, and voila.

The thin, skin-like electronics may usher in a future of earth-friendly gadgets.

It already exists, is on the roads, and has its own flashy commerical

Our photo of the day is brought to you by the dark night sky.