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Nanobiopolymers in cancer therapeutics: advancing targeted drug delivery through sustainable and controlled release mechanisms

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB00599F, Review Article
Shikha Gulati, Nabeela Ansari, Yamini Moriya, Kumud Joshi, Disha Prasad, Gargi Sajwan, Shefali Shukla, Sanjay Kumar, Rajender S. Varma
Nanobiopolymers in cancer therapeutics offer sustainable and targeted drug delivery with controlled release, enhancing treatment efficacy while ensuring sustainability and biodegradability for improved patient care.
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Nanomaterial-mediated photothermal therapy modulates tumor-associated macrophages: applications in cancer therapy

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01928H, Review Article
Yan Li, Yuhao Si, Heng Yin
Nanomaterials for modulating tumor-associated macrophages in photothermal therapy.
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Controlled therapeutic cholesterol delivery to cells for the proliferation and differentiation of keratinocytes

J. Mater. Chem. B, 2024, 12,11110-11122
DOI: 10.1039/D4TB01015A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Krzysztof Berniak, Ahmadreza Moradi, Agata Lichawska-Cieslar, Weronika Szukala, Jolanta Jura, Urszula Stachewicz
The research concept involves investigating how cholesterol endocytosis impacts cells using electrospun fibers as a carrier. We studied keratinocyte proliferation and evaluated gene expression levels for markers of early and late differentiation.
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Nanomaterials and methods for cancer therapy: 2D materials, biomolecules, and molecular dynamics simulations

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01667J, Review Article
Welela M. Kedir, Lunna Li, Yaw Sing Tan, Natasa Bajalovic, Desmond K. Loke
Nanomaterials made from 2D semiconductors and biomolecules are reviewed. Cell-nanoparticle interactions are examined in recent simulations. These nanomaterials and MD simulations reveal novel mechanisms and enable cancer drug delivery and targeting.
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Biomaterials Enhancing Localized Cancer Therapy Activated Anti-Tumor Immunity: A Review

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01995D, Review Article
Jipeng Yao, Zhencun Cui, Feifei Zhang, Haidong Li, Longlong Tian
Localized cancer therapy such as radiotherapy, phototherapy, and chemotherapy are precise cancer treatment strategy, aiming to minimize systemic side effect. However, cancer metastasis remains the primary cause of cancer patients’...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Lactobionic acid modified cobalt coordination polymer-coated peroxymonosulfate nanoparticles generate sulfate/hydroxy dual-radicals for targeted cancer therapy

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01777C, Paper
Jiahui Li, Jiaxuan Li, Zelong Chen, Yichen Wan, Yi Wang, Zhichao Pei, Yuxin Pei
LCP NPs were prepared by forming a coordination polymer on peroxymonosulfate through the coordination between imidazole-2-carboxaldehyde and Co2+, then modified with lactobionic acid to improve the efficacy of sulfate/hydroxy dual-radical therapy.
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H2O2-activated mitochondria-targeting photosensitizer for fluorescence imaging-guided combination photodynamic and radiotherapy

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01653J, Paper
Qiufen Tian, Zifan Zhu, Yun Feng, Shirui Zhao, Hui Lin, Wen Zhang, Zhiai Xu
Radiotherapy is a primary modality in cancer treatment but accompanied by severe side effects to healthy tissues and radiation resistance to some extent. To overcome these limitations, we developed a...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Nanoparticles based image-guided thermal therapy and temperature feedback

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01416B, Review Article
Carlos Jacinto, Wagner Ferreira Silva, Joel Garcia, Gelo P. Zaragosa, Carlo Nonato De Jesus Ilem, Tasso O. Sales, Harrison D. A. Santos, Blessed Isaac C. Conde, Helliomar Pereira Barbosa, Sonia Malik, Surender Kumar Sharma
Nanoparticles have emerged as versatile tools in the realm of thermal therapy, offering precise control and feedback mechanisms for targeted treatments. This review explores the intersection of nanotechnology and thermal...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Cuproptosis in cancer therapy: mechanisms, therapeutic application and future prospects

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01877J, Review Article
Jiawei Hu, Junfei Zhu, Tao Chen, Yudie Zhao, Qingwen Xu, Yan Wang
Cuproptosis is a regulated form of cell death induced by the accumulation of metal ions and is closely linked to aspects of cellular drug resistance, cellular metabolism, and signalling pathways.
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Advancing cancer therapy with a heptamethine carbocyanine dye-conjugated radionuclide drug

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01798F, Paper
Mingxing Huang, Weichen Wang, Yingwei Wang, Rang Wang, Lili Pan, Xin Li, Bo Li, Jingsong Zhang, Ruoxiang Wang, Yi Zhang, Rong Tian
Malignant tumors pose substantial treatment challenges due to their heterogeneity, metastatic potential, and therapeutic resistance, underscoring the urgent need for more effective treatment options.
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Bimetallic doped carbon dot nanozymes for enhanced sonodynamic and nanocatalytic therapy

J. Mater. Chem. B, 2024, Accepted Manuscript
DOI: 10.1039/D4TB01916D, Paper
Yandong Huang, Lanting Jia, Shiqi Zhang, Lan Yan, Lei Li
The conventional inorganic semiconductors are not suitable for acting as nanozymes or sonosensitizers for in vivo therapeutic nanomedicine owing to the lack of excellent biocompatibility. Biocompatible carbon dots (CDs) exhibit...
The content of this RSS Feed (c) The Royal Society of Chemistry




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For Cyrus Broacha, choosing a therapist is same as choosing a shampoo

He goes for the cheapest and closest one



  • Life & Style

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Advancing nanotechnology for neoantigen-based cancer theranostics

Chem. Soc. Rev., 2024, 53,3224-3252
DOI: 10.1039/D3CS00162H, Tutorial Review
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jianhua Zou, Yu Zhang, Yuanbo Pan, Zhengwei Mao, Xiaoyuan Chen
Developing nanotechnology for neoantigen-based precision therapy, including photodynamic therapy, photothermal therapy, radiotherapy, chemo/chemodynamic therapy, immunotherapy, and other therapies.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy

Chem. Soc. Rev., 2024, 53,3976-4019
DOI: 10.1039/D3CS00456B, Review Article
Sisi Wang, Lizhi Gai, Yuncong Chen, Xiaobo Ji, Hua Lu, Zijian Guo
This review focuses on the design strategy, spectroscopic characteristics, and functionalization of mitochondrion-targeted BODIPY dyes, providing an overview of these dyes for mitochondrion-targeted bioimaging and photodynamic therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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What is stereotactic radiation therapy for prostate cancer? How does it compare to other treatments?

Stereotactic radiotherapy uses high doses of radiation to target and kill cancer cells; it uses newer machines that can deliver very focused radiation beams




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Glioblastoma: why immunotherapy may offer hope for brain cancer patients

Recent trials have shown that immunotherapy can safely be delivered through injections into the cerebrospinal fluid; scientists are now exploring how to adapt these methods to penetrate the tumour more effectively




hera

Expert clinic director successfully implements half-hour scheduling system, boosting therapist productivity

As word spread about the success of the half-hour schedule, some early adopters became curious after the clinic director and the team showcased the benefits.




hera

Flora und Fauna in fantastischen Welten : Symposium 2019 in Bonn = Flora and fauna in fantastic worlds / herausgegeben von Denise Burkhard, Marion Gymnich und Dieter Petzold in Verbindung mit Adelheid Kegler [and five others].

Berlin : Peter Lang, [2020]




hera

Boix, Heras, Armengol.

[Madrid] : [Galeria Vandrés], [1973]




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(WO + ICG)@PLGA@lipid/plasmid DNA nanocomplexes as core–shell vectors for synergistic genetic/photothermal therapy

Mater. Chem. Front., 2024, 8,3747-3757
DOI: 10.1039/D4QM00330F, Research Article
Yang Bai, Guoqing Feng, Qingbin Yang, Tingting Hua, Bowen Li, Hao-Lin Guo, Yuan Liu, Qing Yuan, Niansong Qian, Bin Zheng
(WO + ICG)@PLGA@PL could not only achieve a synergistic therapy effect of gene delivery and photothermal effect but also effectively inhibit tumor growth.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Self-assembled phthalocyanine-based nano-photosensitizers in photodynamic therapy for hypoxic tumors

Mater. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QM00602J, Review Article
Lin He, Ding Ma
This paper reviews the potential of self-assembled phthalocyanine-based nano-photosensitizers for overcoming the limitations of photodynamic therapy (PDT) in treating hypoxic tumors.
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Tech Support - Therapist Answers Relationship Questions From Twitter

Licensed family therapist Stephanie Yates-Anyabwile answers the internet's burning questions about relationships. How do you know if someone is gaslighting you? Can a relationship withstand cheating? Do open relationships really work? What causes a marriage of fifteen years to fail? How do you know if your significant other is "The One"? Stephanie answers all these questions and much more. Director: Justin Wolfson Director of Photography: Eric Brouse Editor: Chris Davies Expert: Stephanie R. Yates Line Producer: Joseph Buscemi Associate Producer: Brandon White Production Manager: Eric Martinez Production Coordinator: Fernando Davila Casting Producer: Nicole Ford Camera Operator: Rahil Ashruff Audio: Jeff Gaumer Production Assistant: Patrick Sargent Post Production Supervisor: Alexa Deutsch Post Production Coordinator: Ian Bryant Supervising Editor: Doug Larsen Assistant Editor: Justin Symonds




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Correction: Enhancing the chemotherapeutic efficacy of platinum prodrug nanoparticles and inhibiting cancer metastasis by targeting iron homeostasis

Nanoscale Horiz., 2024, 9,2067-2068
DOI: 10.1039/D4NH90069C, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Fang Ding, Lingpu Zhang, Hao Chen, Haiqin Song, Shiguo Chen, Haihua Xiao
The content of this RSS Feed (c) The Royal Society of Chemistry




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IIT Ropar's new portable knee rehab device to revolutionise post-surgical therapy




hera

New therapeutic avenues for treating TB




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Explained | Why was former Theranos CEO Elizabeth Holmes given 11 years in prison?

Her blood-testing startup claimed to revolutionise testing by detecting hundreds of medical conditions from just a few drops of blood 




hera

Zakłady na żywo STS podaż zakładów on-line u bukmachera STS

Co warto wiedzieć na temat zakładach on-line i zwłaszcza – jak je obstawiać? Odpowiedzi na ów, ale i wiele innych testowań znajdziesz po poniższym artykule. Według naszych opinii STS to jeden spośród czołowych bukmacherów w Polsce. Jego największe wartości to bardzo dobrze działająca aplikacja mobilna, mnogie transmisje live oraz wyśmienicie działające zakłady na energicznie. Bardzo […]




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Hormone Therapy for Prostate Cancer

A fact sheet that describes hormone therapy and its role in treating prostate cancer. Includes information about the different types of hormone therapy, how they are used, and possible side effects.




hera

Targeted Cancer Therapies

A fact sheet that describes targeted cancer therapies, which are drugs that interfere with specific molecules involved in cancer cell growth and survival.




hera

Nanomaterial-based regulation of redox metabolism for enhancing cancer therapy

Chem. Soc. Rev., 2024, Advance Article
DOI: 10.1039/D4CS00404C, Review Article
Xiaodan Jia, Yue Wang, Yue Qiao, Xiue Jiang, Jinghong Li
This review provides a comprehensive summary of the dysregulation of redox metabolism in cancer cells and the advantages and the latest advances in nanomaterial-assisted redox metabolic regulation therapy.
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From cyclotrons to chromatography and beyond: a guide to the production and purification of theranostic radiometals

Chem. Soc. Rev., 2024, 53,10409-10449
DOI: 10.1039/D4CS00802B, Tutorial Review
Brooke L. McNeil, Caterina F. Ramogida
This tutorial review explores the fundamentals and applications behind the production and purification of radiometals in the burgeoning field of radio-theranostics.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A new era of cancer phototherapy: mechanisms and applications

Chem. Soc. Rev., 2024, Advance Article
DOI: 10.1039/D4CS00708E, Review Article
Yuanwei Wang, Ke Ma, Miaomiao Kang, Dingyuan Yan, Niu Niu, Saisai Yan, Panpan Sun, Luzhi Zhang, Lijie Sun, Dong Wang, Hui Tan, Ben Zhong Tang
The past decades have witnessed great strides in phototherapy as an experimental option or regulation-approved treatment in numerous cancer indications.
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Kirigami-enabled stretchable laser-induced graphene heaters for wearable thermotherapy

Mater. Horiz., 2024, 11,2010-2020
DOI: 10.1039/D3MH01884A, Communication
Junyu Chen, Yichao Shi, Binbin Ying, Yajie Hu, Yan Gao, Sida Luo, Xinyu Liu
Stretchable later-induced graphene (LIG) heaters with kirigami structures are produced via laser engraving/cutting for wearable thermotherapy. Such a heater has a rapid electrothermal response and robust performance for on-body use.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Wynnum Herald [electronic journal].

Nationwide News Pty Limited




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Sunday Herald Sun (Melbourne, Australia) [electronic journal].

News Ltd Australia




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Sunday Herald Sun Magazine (Victoria, Australia) [electronic journal].

News Ltd Australia




hera

Sunday Herald Style (Melbourne) [electronic journal].




hera

Redcliffe Bayside Herald [electronic journal].

Nationwide News Pty Limited




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Herald Sun [electronic journal].

News Ltd Australia




hera

Caboolture Shire Herald [electronic journal].

Nationwide News Pty Limited




hera

Bulletin of Counseling and Psychotherapy [electronic journal].




hera

In need of a cell therapy revolution

Indian biotech sector poised for growth with cell and gene therapies revolutionising healthcare, positioning India as a global leader




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Zydus Cadila gets USFDA nod for drug trials to treat chemotherapy-induced anemia




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Two in one: merging photoactivated chemotherapy and photodynamic therapy to fight cancer

Chem. Sci., 2024, 15,17760-17780
DOI: 10.1039/D4SC04608K, Perspective
Open Access
Kirill M. Kuznetsov, Kevin Cariou, Gilles Gasser
Combining photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) into one single compound allows to achieve more efficient light-induced therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Photo-triggered NO release of nitrosyl complexes bearing first-row transition metals and therapeutic applications

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06820C, Review Article
Open Access
Seungwon Sun, Jisu Choe, Jaeheung Cho
In biological systems, nitric oxide (NO) is a crucial signaling molecule that regulates a wide range of physiological and pathological processes. Given the significance of NO, there has been considerable...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Photoactivated hydride therapy under hypoxia beyond ROS

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06576J, Edge Article
Open Access
Xia Wang, Yijian Gao, Ting Wang, Zhaobin Wang, He Hang, Shengliang Li, Fude Feng
As compared to oxidative phototherapy, studies on reactive reductive species-participating photodynamic therapy (PDT) are rare. Porphyrins are typical photosensitizers restricted with oxygen level, but efficacy and selectivity are always uncompatible...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A gravity-driven tissue chip to study the efficacy and toxicity of cancer therapeutics

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC00404C, Paper
Open Access
Pouria Rafsanjani Nejad, Astha Lamichhane, Prasiddha Guragain, Gary Luker, Hossein Tavana
A 96-well plate format, fully-automated multi-organ tissue chip array with gravity-driven flow for cancer research.
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Immunotherapy approach shows potential in some people with metastatic solid tumors

A new cellular immunotherapy approach shrank tumors in 3 of 7 patients with metastatic colon cancer, in a small NCI clinical trial. Normal white blood cells from each patient were genetically engineered to produce receptors that recognize and attack their specific cancer cells.




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Immunotherapy after surgery helps people with high-risk bladder cancer live cancer-free longer

An NCI trial shows that giving patients pembrolizumab after surgery for high-risk muscle invasive bladder cancer doubles the median length of time that they remain cancer free, compared with observation alone after surgery.




hera

Pathogenesis of Alzheimer's disease and therapeutic strategies involving traditional Chinese medicine

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00660G, Review Article
Shutang Li, Jinfei Yang
As research on AD has progressed, TCM and its active ingredients have increasingly played a crucial role in clinical treatment. This article summarizes extracts from TCM and briefly elucidates their pharmacological mechanisms against AD.
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