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MRI-Guided Radiation Therapy Reduces Long-Term Side Effects for Patients with Prostate Cancer

After a comprehensive two-year follow-up, researchers at the UCLA Health Jonsson Comprehensive Cancer Center found that MRI-guided stereotactic body radiotherapy (SBRT) for prostate cancer significantly reduced long-term side effects and improved quality of life, particularly in bowel and sexual health, compared to conventional CT-guided treatment.




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Change is the only constant—Heraclitus, Greek philosopher

Get ready for some very hard, yet rewarding, work. Being an agent of change for the better is always rewarding, no matter what the industry, profession or hobby. Anything worth accomplishing is going to take a lot of work—just look at what we have seen at the recent Summer Olympics.




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Bio blog: New therapy targeting the malaria parasite’s Achilles’ heel

Malaria is a devastating disease, affecting 200 million people worldwide and causing more than 600 000 deaths each year. In the past decade, great inroads have been made in reducing the number of infections, primarily through the implementation of insecticide-laced bed nets, and also reducing the death rate with combination therapies. However the emergence of drug-resistant malaria is rendering these therapies less effective, and there is an urgent need to develop novel therapies to cure malaria.




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GitHub - bahaaador/bluetooth-usb-peripheral-relay: Bluetooth to USB HID relay using a Raspberry Pi Zero




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Creating a BLE Peripheral with BlueZ | Punch Through




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Sport | Ex-Wales flanker Popham hopes next World Rugby chairman heralds new dawn in concussion issue

Former Wales flanker Alix Popham has told AFP he hopes the new chairman of World Rugby will push for the changes required to prevent players from suffering the long-term effects of successive head injuries, as he has done.




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Republicans win 218 House of Representatives seats, completing party's sweep into power alongside Trump - Deccan Herald

  1. Republicans win 218 House of Representatives seats, completing party's sweep into power alongside Trump  Deccan Herald
  2. U.S. Republicans complete power takeover with House majority  The Hindu
  3. Republicans win control of House, cementing a GOP trifecta under Trump  Deccan Herald
  4. After Senate Win, Republicans Retain House Majority; Trump Secures Clear Path To Enact His Policies  The Times of India




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23andMe lays off 40% of its workforce, ends therapeutics division

23andMe is laying off 40 per cent of its workforce, or more than 200 employees, and discontinuing its therapeutics division as the struggling genetic testing company attempts to slash costs.




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Sheraton Jumeirah Beach Resort Unveils a New Era of Modern Comfort with a Stunning Transformation

Sheraton Jumeirah Beach Resort is proud to announce its relaunch following an extensive revitalization, redefining the guest experience at this iconic destination. As the first hotel built in the Jumeirah Beach Residence (JBR) area, Sheraton Jumeirah Beach Resort has set the standard for excellence in hospitality for over two decades. This transformation ushers in a new era, blending modern design, amenities, and cutting-edge technology while preserving the resort’s rich history and cherished legacy. The reinvention of the Resort is driven by the vision of bringing people together through shared moments and spaces. The newly reimagined rooms and suites offer a sophisticated fusion of modern design and natural textures, with a color palette inspired by the serene beachfront setting. All rooms have been thoughtfully equipped to cater to the diverse needs of today’s travellers with the latest technologies, providing guests with a seamless blend of comfort and innovation. The bathrooms to...




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Dejo Kappan vs Deccan Herald on 7 November, 2024

Dr. A.K.Jayasankaran Nambiar, J.

These writ petitions raise an interesting question as regards the scope, content and extent of the right to freedom of speech and expression enuring to the media when they report facts about ongoing criminal investigations or the proceedings in cases pending adjudication before the various adjudicatory forums in the country. The writ petitions were initially considered by a Full Bench of this Court. However, by an order dated 24.05.2018, the Full Bench took the view that in the light of an earlier decision of another Full Bench of this Court in S. Sudin v. Union of India and Others - [2015 (2) KLT 296 (FB)], these matters needed to be referred to a Larger Bench of five Judges for consideration. It is thus, and pursuant to an order dated 02.09.2024 of the Hon'ble the Acting Chief Justice, that these matters are now before us.




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Melatonin treatment as an anti-aging therapy for UV-related degradation of perovskite solar cells

J. Mater. Chem. A, 2024, Advance Article
DOI: 10.1039/D4TA01332H, Paper
Fei Liu, Agnes Valencia, Yuhua Zhu, Xiangyang Zhang, Weilu Li, Walid A. Daoud
With the ability to absorb UV light and scavenge radicals, the melatonin modified perovskite exhibits enhanced anti-aging and resistance to UV-related degradation.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A multifunctional “three-in-one” fluorescent theranostic system for hepatic ischemia–reperfusion injury

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC04962D, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Jihong Liu, Dongni Yin, Wen Zhang, Xin Wang, Tony D. James, Ping Li, Bo Tang
A single-component multifunctional fluorescent theranostic system (MB-Gly) for use during hepatic ischemia-reperfusion injury (HIRI) has been developed.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Chemical synthetic approaches to mimic the TRAIL: promising cancer therapeutics

RSC Med. Chem., 2024, 15,3639-3651
DOI: 10.1039/D4MD00183D, Review Article
Abdullah-Al Masum, Shin Aoki, Md. Mahbubur Rahman, Yosuke Hisamatsu
TRAIL induced apoptosis signalling by death receptors (DR4/DR5).
The content of this RSS Feed (c) The Royal Society of Chemistry




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Stachydrine, a pyrrole alkaloid with promising therapeutic potential against metabolic syndrome and associated organ dysfunction

RSC Med. Chem., 2024, 15,3652-3673
DOI: 10.1039/D4MD00425F, Review Article
Semim Akhtar Ahmed, Prasenjit Manna, Jagat Chandra Borah
Metabolic syndrome is a multifaceted condition marked by interconnected risk factors, significantly increasing the risk of serious diseases like cardiovascular disease, type 2 diabetes, and stroke.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Evaluating the therapeutic potential of genetically engineered probiotic Zbiotics (ZB183) for non-alcoholic steatohepatitis (NASH) management via modulation of the cGAS-STING pathway

RSC Med. Chem., 2024, 15,3817-3836
DOI: 10.1039/D4MD00477A, Research Article
Maha Saad, Walaa Ibrahim, Amany Helmy Hasanin, Aya Magdy Elyamany, Marwa Matboli
ZBiotics administration in the NASH model downregulated the RNA panel (MAPK3, EDN1, TNF, miR-6888-5p, lncRNA RABGAP1L-DT-206), restored intestinal barrier integrity, reduced hepatic inflammation, and improved lipid profiles and liver enzymes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy

RSC Med. Chem., 2024, 15,3912-3912
DOI: 10.1039/D4MD90040E, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nilesh Raghunath Khedkar, Milind Sindkhedkar, Alex Joseph
The content of this RSS Feed (c) The Royal Society of Chemistry







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Albanese flies to South America on trade rescue mission after Trump victory - Sydney Morning Herald

  1. Albanese flies to South America on trade rescue mission after Trump victory  Sydney Morning Herald
  2. Albanese channels Turnbull in Trump tariff fight  The Australian Financial Review
  3. Live: Albanese lands in Peru ahead of APEC forum  ABC News
  4. Australia news LIVE: Trade tussle awaits PM at APEC meeting in Peru; Trump’s appointment spree continues  The Age





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Disease modifying therapies for relapsing multiple sclerosis




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Deciphering Peripheral Taste Neuron Diversity: Using Genetic Identity to Bridge Taste Bud Innervation Patterns and Functional Responses

Peripheral taste neurons exhibit functional, genetic, and morphological diversity, yet understanding how or if these attributes combine into taste neuron types remains unclear. In this study, we used male and female mice to relate taste bud innervation patterns to the function of a subset of proenkephalin-expressing (Penk+) taste neurons. We found that taste arbors (the portion of the axon within the taste bud) stemming from Penk+ neurons displayed diverse branching patterns and lacked stereotypical endings. The range in complexity observed for individual taste arbors from Penk+ neurons mirrored the entire population, suggesting that taste arbor morphologies are not primarily regulated by the neuron type. Notably, the distinguishing feature of arbors from Penk+ neurons was their propensity to come within 110 nm (in apposition with) different types of taste-transducing cells within the taste bud. This finding is contrary to the expectation of genetically defined taste neuron types that functionally represent a single stimulus. Consistently, further investigation of Penk+ neuron function revealed that they are more likely to respond to innately aversive stimuli—sour, bitter, and high salt concentrations—as compared with the full taste population. Penk+ neurons are less likely to respond to nonaversive stimuli—sucrose, umami, and low salt—compared with the full population. Our data support the presence of a genetically defined neuron type in the geniculate ganglion that is responsive to innately aversive stimuli. This implies that genetic expression might categorize peripheral taste neurons into hedonic groups, rather than simply identifying neurons that respond to a single stimulus.




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Praktikum im Bereich Filmverleih/Marketing/Kino-Herausbringung

Du kennst dich mit Social Media und Kooperationsmarketing aus bzw. möchtest mehr darüber lernen? Du hast eine große Leidenschaft für Filme und möchtest ihren Auswertungsprozess mit deiner Arbeit unterstützen? Du arbeitest organisiert, eigenständig und gewissenhaft? Dann suchen wir genau Dich! Unser Hamburger Filmverleih Little Dream Pictures bringt sowohl unterhaltsame Familienfilme als auch Arthouse-Produktionen in die deutschen Kinos und übernimmt deren Vertrieb und Vermarktung. Wir sind Teil eines… | Little Dream Pictures GmbH – Hamburg




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GT Medical Technologies Announces Data Demonstrating Positive Local Control and Safety Outcomes with GammaTile Therapy for Large Brain Metastases




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Glioblastoma Utilizes Fatty Acids and Ketone Bodies for Growth Allowing Progression during Ketogenic Diet Therapy




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New Webinar Added: Assessment of Treatment Response to Established and Novel Therapies in Glioblastoma Patients using Metabolic and Physiologic MR Imaging Techniques




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Cs-131 brachytherapy for patients with recurrent glioblastoma combined with bevacizumab avoids radiation necrosis while maintaining local control




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Expanded and Rebranded: Louisville-Original Mindfulness and Therapy Center Rejuvenates Brand and Opens New Locations

The Mindfulness Center, formerly known as Louisville Mindfulness Center, has rebranded to envelop their recent expansion from one Kentucky location to two – one in Louisville and one in Lexington – as well as employing licensed therapists able to serve all of Kentucky, as well as those in Indiana and Florida via telehealth services.




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Grünenthal's resiniferatoxin receives Breakthrough Therapy Designation from U.S. FDA for pain associated with osteoarthritis of the knee

Aachen, Germany, 22 May 2023 – Grünenthal today announced that its investigational non-opioid medicine resiniferatoxin (RTX), currently undergoing clinical Phase III development, received Breakthrough Therapy Designation from the U.S. Food and Drug Administration (FDA) for pain associated with osteoarthritis (OA) of the knee. The decision is based on clinical phase I and II data indicating significant pain relief and a favourable safety profile.




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RHEACELL announces "First Patient In": EB-Haus in Salzburg, Austria starts pivotal study for stem cell therapy

RHEACELL announces "First Patient In": EB-Haus in Salzburg, Austria starts pivotal study for stem cell therapy for severe forms of Epidermolysis bullosa that is longed for by those affected




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Acousia Therapeutics to present its clinical Phase 2 PROHEAR study on hearing loss treatment candidate ACOU085 at upcoming conferences

Acousia Therapeutics GmbH, a Tübingen-based clinical stage biotech company focused on the enhancement and preservation of natural hearing, will be presenting the ACOU085 Phase 2 PROHEAR clinical study at the HansonWade 4th Inner Ear Disorders Therapeutics Summit in Boston (MA) from August 20–22, and at the 36th World Congress of Audiology from September 19–22, 2024.




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Leftchannel Digital Arts Studio Creates Experiential Art Piece at the Renovated Sheraton Dallas Hotel

Columbus, Ohio-based leftchannel Content Design Studio was enlisted to design a modern digital art display under the creative direction of Alberto Scirocco for the iconic Sheraton Dallas Hotel.




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Charlotte, NC Author Publishes Art Therapy Book

A Collection of Poems, Songs, Drawings, and Paintings for Art Therapy Sessions.




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Aromatherapy Diffuser Market Set for Strong Growth: Projected to Reach $3.45 Billion by 2030

(EMAILWIRE.COM, November 01, 2024 ) Aromatherapy Diffuser Market was valued at USD 1.87 Bn in 2023 and is expected to reach USD 3.45 Bn by 2030, at a CAGR of 9.17 % during the forecast period Aromatherapy Diffuser Market overview: The aromatherapy diffuser market has witnessed significant growth...




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Inclined Bed Therapy: Tilt your bed for healthful sleep

Inclined Bed Therapy or IBT is the brain child of Andrew Fletcher, who discovered in the 1990's that gravity actually helps to drive circulation of the sap in trees. From there, it was a short step to ask whether this was also true for animals and humans. This posed the question "why on Earth do people sleep flat?" So Andrew suggested that people slightly raise the head end of their bed and see if any changes in their health are noticeable. This is one of the numerous anecdotes ... stories of personal success people have reported after raising the head end of their bed by just five or six inches. "Over two years ago I sat in the armchair reading a small advert which asked people to raise their bed by six inches at the head and to reply and tell what benefits had been noted. (No explanation was given) At the time I could not move my neck to my left or right side and it ached continuously. I was unable to sleep at night as i could not get comfortable. I was only able to turn by gently easing myself. It took about three to four turns. Getting out of bed was a major obstacle. I needed help to dress and undress. I spent most of my nights in the chair with the result that I was always tired and had no energy. My problem is osteoporosis of the upper and lower spine. I had tried hormone replacement therapy and wasted a small fortune with bone specialists and osteopaths. I was resigned to living my days out as best I could, having been told that there was nothing more that could be done for me. I expected nothing but had nothing to lose, so Harry raised the bed by six inches. We did not take it very seriously but were happy to try anything. On the fourth night I had the first full nights sleep since I don't remember when. By the end of the week I was sleeping naturally and turning over with ease. My dressing was a problem no longer, each day it became easier. I was able to turn my head without pain, right or left, to see the clock without getting up from my chair. There have been many other benefits too. I have worn glasses from the age of seven years and I am now sixty eight years. Last year was the first time I was told that there was a small improvement. My hair appears thicker, my hair brush needs cleaning less often. Harry had a large suppurating scar since he was six years old. He has had to continually dress it all of his life. But now it has healed up. His ear which constantly gave him trouble with a discharge has now cleared up completely. We both feel that the clock has been put back for us!" Ruby, 2nd April 1998 Other such stories can be found on the Inclined Bed Therapy website and on the facebook page with the same name...




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Chromotherapy in Cancer

In 2007, I posted two articles on this site suggesting that cancer had something to do with the energy mechanism of the human body. I am coming back to this through a comment on one of those articles by Viorel Bungau, a family medical doctor in Romania. The two previous articles are: Cancer and ATP: The Photon Energy Pathway Could cancer be a functional deviation of the cellular energy production mechanism that is open to correction by relatively simple means instead of a genetic mutation that is passed down through cell division? Heinrich Kremer, MD, says that this is indeed the case. His hypothesis of a photon-mediated cellular energy pathway may turn out to substantially add to our understanding of what cancer is, and why such natural substances as curcumin may be effective cancer fighting agents. Cancer: The ATP-Photon Hypothesis Could cancer be a result of the functional degradation of a cellular photon absorption pathway that is basic to the production of ATP, the cellular energy molecule? And could tumor cells merely be executing an age-old survival program they retained from the time of unicellular existence? An interesting new hypothesis of cancer causation spells out why some cells all of a sudden start dividing to form tumors, and how that urge to sustained growth could likely be 'switched off. Chromotherapy: The healing power of colors (image found here) Here (with some minor edits) is what Dr Bungau originally posted as a comment on the second article... CHROMOTHERAPY IN CANCER Dear Professor, Medical practitioner, I am passionate about cancer research. After years of study, we came to a hypothesis to be verified experimentally in collaboration with a field center. After many attempts (direct approach), no one has agreed to do this experiment. Please help make this research proposal possible. If proven true, it would change the medical approach to diagnosis and treatment of cancer and beyond. Yours sincerely, Dr.Viorel Bungau...




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TNP - Hydrogen Peroxide Therapy

Provides background on hydrogen peroxide therapy and includes guidelines on various forms of administering hydrogen peroxide therapy. Also discusses the controversy on ingesting hydrogen peroxide.




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TNP - Oxygen Therapy

Provides information on the basis of oxygen therapy and guidelines on administering oxygen therapy using various methods.




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Bowling Therapy Ash Grey T-Shirt

For Some There's Therapy, For The Rest Of Us There's Bowling Ash Grey T-Shirt - For some there's therapy, for the rest of us there's bowling. Sometimes the best way escape reality a little bit to relax, unwind, think about life is to head to the bowling alley and knockdown some pins. There's just something about rolling a bowling ball down the lane, hearing the crash of the pins as they plow into each other to release tension and stress.




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Bowling Therapy Baseball Jersey

For Some There's Therapy, For The Rest Of Us There's Bowling Baseball Jersey - For some there's therapy, for the rest of us there's bowling. Sometimes the best way escape reality a little bit to relax, unwind, think about life is to head to the bowling alley and knockdown some pins. There's just something about rolling a bowling ball down the lane, hearing the crash of the pins as they plow into each other to release tension and stress.




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Bowling Therapy BBQ Apron

For Some There's Therapy, For The Rest Of Us There's Bowling BBQ Apron - For some there's therapy, for the rest of us there's bowling. Sometimes the best way escape reality a little bit to relax, unwind, think about life is to head to the bowling alley and knockdown some pins. There's just something about rolling a bowling ball down the lane, hearing the crash of the pins as they plow into each other to release tension and stress.




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Bowling Therapy Beer Stein

For Some There's Therapy, For The Rest Of Us There's Bowling Beer Stein - For some there's therapy, for the rest of us there's bowling. Sometimes the best way escape reality a little bit to relax, unwind, think about life is to head to the bowling alley and knockdown some pins. There's just something about rolling a bowling ball down the lane, hearing the crash of the pins as they plow into each other to release tension and stress.




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Bowling Therapy Button

For Some There's Therapy, For The Rest Of Us There's Bowling Button - For some there's therapy, for the rest of us there's bowling. Sometimes the best way escape reality a little bit to relax, unwind, think about life is to head to the bowling alley and knockdown some pins. There's just something about rolling a bowling ball down the lane, hearing the crash of the pins as they plow into each other to release tension and stress.




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Bowling Therapy Calendar Print

For Some There's Therapy, For The Rest Of Us There's Bowling Calendar Print - For some there's therapy, for the rest of us there's bowling. Sometimes the best way escape reality a little bit to relax, unwind, think about life is to head to the bowling alley and knockdown some pins. There's just something about rolling a bowling ball down the lane, hearing the crash of the pins as they plow into each other to release tension and stress.




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Bowling Therapy Coffee Cup

For Some There's Therapy, For The Rest Of Us There's Bowling Coffee Mug - For some there's therapy, for the rest of us there's bowling. Sometimes the best way escape reality a little bit to relax, unwind, think about life is to head to the bowling alley and knockdown some pins. There's just something about rolling a bowling ball down the lane, hearing the crash of the pins as they plow into each other to release tension and stress.




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Bowling Therapy Dog T-Shirt

For Some There's Therapy, For The Rest Of Us There's Bowling Dog T-Shirt - For some there's therapy, for the rest of us there's bowling. Sometimes the best way escape reality a little bit to relax, unwind, think about life is to head to the bowling alley and knockdown some pins. There's just something about rolling a bowling ball down the lane, hearing the crash of the pins as they plow into each other to release tension and stress.




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Bowling Therapy Fitted T-Shirt

For Some There's Therapy, For The Rest Of Us There's Bowling Fitted T-Shirt - For some there's therapy, for the rest of us there's bowling. Sometimes the best way escape reality a little bit to relax, unwind, think about life is to head to the bowling alley and knockdown some pins. There's just something about rolling a bowling ball down the lane, hearing the crash of the pins as they plow into each other to release tension and stress.




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Bowling Therapy Golf Shirt

For Some There's Therapy, For The Rest Of Us There's Bowling Golf Shirt - For some there's therapy, for the rest of us there's bowling. Sometimes the best way escape reality a little bit to relax, unwind, think about life is to head to the bowling alley and knockdown some pins. There's just something about rolling a bowling ball down the lane, hearing the crash of the pins as they plow into each other to release tension and stress.




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Bowling Therapy Hooded Sweatshirt

For Some There's Therapy, For The Rest Of Us There's Bowling Hooded Sweatshirt - For some there's therapy, for the rest of us there's bowling. Sometimes the best way escape reality a little bit to relax, unwind, think about life is to head to the bowling alley and knockdown some pins. There's just something about rolling a bowling ball down the lane, hearing the crash of the pins as they plow into each other to release tension and stress.