act

Novel quinoxaline-derived derivatives: design, synthesis, bioactive evaluation, SARs and preliminary antibacterial mechanism

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00670D, Research Article
Yuting Liu, Pengju Yang, Yunyun Zhou, Zhiwen Zhou
In the current study, we have designed and prepared a series of quinoxaline-based compounds, which were derived from o-phenylenediamine. Among which, compounds 5m-p displayed good to moderate antibacterial activity with...
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Enhancing the antimycobacterial efficacy of pyridine-4-carbohydrazide: linkage to additional antimicrobial agents via oxocarboxylic acids

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00663A, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Václav Pflégr, Klára Konečná, Jiřina Stolaříková, Jan Ősterreicher, Ondřej Janďourek, Martin Krátký
Linking pyridine-4-carbohydrazide to other antimicrobial agents via oxocarboxylic acids significantly enhances efficacy against mycobacteria with promising selectivity and safety profiles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Synthesis of cationic N-acylated thiazolidine for selective activity against Gram-positive bacteria and evaluation of N-acylation's role in membrane-disrupting activity

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00626G, Research Article
Aleena Pious, Vignesh Venkatasubramanian, Dharshini Karnan Singaravelu, Subburethinam Ramesh, Fuad Ameen, Anbazhagan Veerappan
Lipidation modulates the Gram-selective antibacterial activity of QPyNATh.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

3-Thio-3,4,5-Trisubstituted-1,2,4-Triazoles: High Affinity Somatostatin Receptor-4 Agonist Synthesis and Structure-Activity Relationships

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00597J, Research Article
Albert Michael Crider, Audrey Hospital, Karin Sandoval, William Neumann, Stephen Kukielski, Lejla Garic, Kristen Ingold, Matthew Dunahoo, Khush Srabony, Rafael Frare, Olivia Slater, Nathan Peel, Maria Kontoyianni, Ken Witt
Somatostatin receptor-4 (SST4) is a therapeutic target for several conditions, including Alzheimer’s disease, seizures, neuropsychiatric disorders, and pain. Our previous work on 1,2,4-triazole derivatives led to enhanced SST4 binding affinity,...
The content of this RSS Feed (c) The Royal Society of Chemistry




act

A practical guide for the assay-dependent characterisation of irreversible inhibitors

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00707G, Review Article
Lavleen K. Mader, Jessica E. Borean, Jeffrey W. Keillor
Kinetic evaluations for assay dependent characterization of irreversible inhibitors.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Will decide on sharing stage with actor Vijay in consultation with VCK leaders: Thirumavalavan

Mr. Thirumavalavan told reporters in Tiruchi that the book release event was not something that was planned recently, and that he had consented to take part in it almost a year ago




act

Case filed against actor Kasthuri over remarks on Telugu community




act

Farmers demand withdrawal of Tamil Nadu Land Consolidation Act

The Coordination Committee of All Farmers’ Associations of Tamil Nadu says the State government has created a situation where industries can acquire fertile lands




act

555: React Documentary, Front of the Front End, Fast Fallacy, and Best Practices

Reacting to the React.js documentary, is there still jobs for front of the front end anymore? The fast fallacy in frameworks, best practices, dealing with too much or too little isolation, and AI test generation.




act

603: Deno, React Alternatives, and Copilot Concerns with Triple Threat Josh Collinsworth

Josh (or Jsoh) stops by to talk about his work at Deno, recent blog posts on Copilot, why Svelte is awesome and React is not, Apple and PWA, and building word games on the web.




act

611: React! TypeScript! Jobification! Drupal!

Dave & Chris and thoughts on career advice that worked 3 years ago but isn't as helpful now, marking tests with ChatGPT, is taking a Drupal job in 2024 a good idea, Chris got #gear sniped, P3 color follow up, the confusing File System APIs, and where did all the lightboxes go?




act

Building practices for the future

Sacred Groves in Auroville is being built using ecologically sensitive construction methods and material.




act

Gunning for a slice of billion-dollar defence contracts 

How a college project birthed a bootstrapped manufacturer of components for the armed forces 




act

Balrampur Chini hopes success of polylactic acid plant will be sweet

In conversation with Avantika Saraogi, ED, and Stefan Barot, President, Chemicals Division, Balrampur Chini Mills




act

The delicate balance in doctor-patient interaction

How clear communication and accountability in healthcare can significantly improve patient outcomes




act

Compacted

New Arrival: Skoda might be late to enter the sub-four-metre SUV segment, but the all-new Kylaq shows that it’s not unprepared




act

Gopal Rai calls meeting over Winter Action Plan progress 




act

‘No religion encourages an activity that creates pollution: SC on firecrackers

The Supreme Court wondered why the Delhi Government delayed imposition of the ban on firecrackers till October 14, when the order of ban was issued




act

Amateur Radio Activated for Late Season Hurricane

A rare November hurricane made landfall in western Cuba as a Category 3 storm Wednesday and continued to move slowly toward the northwest Thursday morning. Volunteer ham radio operators were there to provide surface reports to the National Hurricane Center in Miami.

Hurricane Rafael left Cuba’s 10 million residents without power and on Thursday afternoon was a Category 2 storm moving away from C...




act

Rare California Island to be Activated for Armed Forces Day, First Time in 53 Years

On Armed Forces Day, May 1971, 53 years ago, two amateur operators working as WZ6SNI, activated San Nicolas Island, IOTA NA-066. At 61 miles, San Nicolas is the most remote of the Channel Islands off the coast of Southern California and is owned by the US Navy.

Now, weather permitting, Will Costello, WC6DX, has been authorized to be active from San Nicolas Island November 8 - 12, 2024. He is tak...




act

Open sale of hazardous pesticides continues to impact the health of farmers in Maharashtra

In 2017, reports of pesticide poisoning emerging from Maharashtra drew global criticism against India’s pesticide regulation policies, yet not much appears to have changed since then




act

Mango output is set to increase by 14% this year; heat wave unlikely to impact yields

The total production of mangos could jump to 24 million tonnes in the 2023-24 crop year, as against 21 million tonnes in 2022-23




act

Above-normal pre-monsoon rain triggers agriculture activities in Raichur district of Karnataka

The district received 26.5 mm of rain in 72 hours against the average of 1.9 mm




act

First of its kind ‘Product Santhe’ at UAS attracts 15,000 visitors 

Products like coconut oil, handmade scented soaps and face creams, value added products of millets, nutritional laddu, bakery products, ready to cook powders and mixtures and pickles were also popular among the visitors. 




act

Scientists found a bacteria tricked a wasp to get rid of its males

A new study reports Wolbachia may have taken it a bit too far, after scientists found it manipulated the evolution of Encarsia formosa wasps




act

Centre launches new system to understand cropping patterns, impact of weather

Union Agriculture Ministry launches Krishi-DSS, a digital platform providing real-time data insights for stakeholders in Indian agriculture




act

Anantapur Collector urges farmers to adopt natural practices

V. Vinod Kumar visits several watershed structures in the district implemented by Accion Fraterna Ecology Centre with funding from NABARD




act

Climate change impact harsher on poorer farmers in India: FAO report

FAO recommends enhanced social security net for all, Niti Aayog member says India doing its best to deal with climate change.




act

Volkswagen India enters compact sedan segment




act

Investors can now file class action suits against errant cos




act

Delhi Ganesh, a great supporting actor, is no more

Though he had acted with other actors and in a lot of films, Ganesh used to say that his roles in Kamal Haasan starrers earned him a name




act

Delhi Ganesh: An actor who could be anyone on screen

Delhi Ganesh, one of the most versatile artists of Tamil cinema, leaves behind a legacy of warmth, trust, and laughter




act

State Planning Commission in Tamil Nadu flags sector-wise impact from heat wave, calls for measures

Heat stress is repeatedly causing disruptions in ecological and economic systems, SPC report titled ‘Beating The Heat-Tamil Nadu Heat Mitigation Strategy’ said.




act

Hindu Succession Act supports daughters but lets down widows and mothers, says Madras High Court

The loss to one section of women has been overlooked in the euphoria over the gain to another section, says Justice N. Seshasayee




act

Dynamics of phase-separated microdroplets near the contact line of evaporating all-aqueous drops

Soft Matter, 2024, 20,8260-8266
DOI: 10.1039/D4SM01056F, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Rahul Rai, Maheshwar Gopu, Senthan Pugalneelam Parameswaran, Tapan Chandra Adhyapak, Dileep Mampallil
Evaporation of multicomponent drops can induce liquid–liquid phase separation and spatial reconfiguration of phases through complex dynamics near the contact line.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

The impact of cross-linker distribution on magnetic nanogels: encapsulation, transport and controlled release of the tracer

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00797B, Paper
Open Access
Ivan S. Novikau, Ekaterina V. Novak, Sofia S. Kantorovich
Differences in crosslinker concentration between the core and periphery of a magnetic nanogel slow down the release of a non-magnetic cargo.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Geometrical impacts of platonic particles on nematic liquid crystal dynamics

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00870G, Paper
Stiven Villada-Gil, Monirosadat Sadati, Juan D. Ospina-Correa, Daniel A. Olaya-Muñoz, Juan P. Hernández-Ortiz, José A. Martínez-González
In this work, we studied the defect dynamics of platonic-like colloidal particles immersed in a nematic liquid crystal under flow conditions, analyzing the behavior of disclinations for each of these polyhedra.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Drop deformation in a planar elongational flow: impact of surfactant dynamics

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00642A, Paper
Julian Wailliez, Paul Regazzi, Anniina Salonen, Paul G. Chen, Marc Jaeger, Marc Leonetti, Emmanuelle Rio
We measure the deformation of a drop under an extensional flow. The drop is less deformed than for a pure liquid because of the depletion of surfactants at the tips, which we attribute to the adsorption/desorption dynamics of the surfactants.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Network interactions simultaneously enhance stiffness and lubricity of triple-network hydrogels

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00969J, Paper
Nabila Ali, Connor J. Demott, Olivia F. Dingus, Melissa A. Grunlan, Alison C. Dunn
Tough hydrogels with a charge-variable third network were assessed for biomimicking lubricity in both water and FBS solution.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Microrheology of gemini surfactants at interfaces and in solutions in the dilute and semidilute regimes

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00860J, Paper
Mayssa Medfai, Antonio Stocco, Christophe Blanc, Maurizio Nobili, Martin In
The interface of semidilute Gemini surfactant solutions remains fluid and is less viscous than the bulk. Depletion of the viscosity near the interface plays a key role in microrheology.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Controlling wall–particle interactions with activity

Soft Matter, 2024, 20,8395-8406
DOI: 10.1039/D4SM00634H, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Luke Neville, Jens Eggers, Tanniemola B. Liverpool
The interaction between a disk and wall in an active nematic depends on a combination of activity and anchoring, with contractile nematics repelling disks with planar anchoring.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Strain rate controls alignment in growing bacterial monolayers

Soft Matter, 2024, 20,8468-8479
DOI: 10.1039/D4SM00625A, Paper
Blake Langeslay, Gabriel Juarez
A model of cell alignment in confined growing bacterial monolayers connecting net monolayer deformation to the behavior of individual cells.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Cell shape and orientation control galvanotactic accuracy

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00952E, Paper
Ifunanya Nwogbaga, Brian A. Camley
We study the physical factors that control the accuracy with which elongated cells can sense the direction of an electric field, exploring whether cells are more accurate sensors when oriented parallel to the field or perpendicular to it.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Mechanical characterization of freestanding lipid bilayers with temperature-controlled phase

Soft Matter, 2024, 20,8524-8537
DOI: 10.1039/D4SM00706A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Arash Yahyazadeh Shourabi, Roland Kieffer, Djanick de Jong, Daniel Tam, Marie-Eve Aubin-Tam
Lipid membranes formed in a microfluidic device are studied with temperature-controlled optical tweezers, revealing how mechanical properties of ripple phase and gel-fluid phase-separated membranes change when heated above the transition temperature.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Retraction: Self-assembled organic nanotubes embedding hydrophobic molecules within solid bilayer membranes

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM90171A, Retraction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Naohiro Kameta, Masumi Asakawa, Mitsutoshi Masuda, Toshimi Shimizu
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Retraction: Supramolecular organic nanotubes: how to utilize the inner nanospace and the outer space

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM90172J, Retraction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Naohiro Kameta, Hiroyuki Minamikawa, Mitsutoshi Masuda
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Linking local microstructure to fracture location in a two-dimensional amorphous solid under isotropic strain

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00486H, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Max Huisman, Axel Huerre, Saikat Saha, John C. Crocker, Valeria Garbin
Machine learning predicts possible crack location in experiments of a fracturing colloid monolayer, shown along with the actual crack path.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Rolling and ordering of micro rods in shear flow induced by rod wall interactions

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00999A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Martin Wittmann, Igor M. Kulić, Antonio Stocco, Juliane Simmchen
We use experiments and theoretical models to investigate the rolling and translational motion of rod-shaped micro particles close to a solid wall in the presence or absence of shear flow.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Modeling nematic phase main-chain liquid crystal elastomer synthesis, mechanics, and thermal actuation via coarse-grained molecular dynamics

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM00528G, Paper
Nicolas Herard, Raja Annapooranan, Todd Henry, Martin Kroger, Shengqiang Cai, Nicholas Boechler, Yelena Sliozberg
This paper presents a coarse-grained molecular dynamics simulation study of the synthesis, mechanics, and thermal actuation of nematic phase main-chain liquid crystal elastomers (LCEs), a type of soft, temperature-responsive, polymeric...
The content of this RSS Feed (c) The Royal Society of Chemistry




act

Thickness-dependent response of aerosol-jet-printed ultrathin high-aspect-ratio electrochemical microactuators

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM00886C, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ji Zhang, Jeremy J. Baumberg, Sohini Kar-Narayan
Trilayer electrochemical actuators comprising an electrolyte layer sandwiched between two electrode layers have been shown to exhibit large deformations at low actuation voltages. Here we report aerosol-jet printing (AJP) of...
The content of this RSS Feed (c) The Royal Society of Chemistry