BACKGROUND:The threshold of the lower limit of the normal range of lung function has been suggested to be more accurate than the 0.7 fixed ratio (FEV1/FVC < 0.7) for a diagnosis of COPD. We aimed to explore the health status and risk factors of patients overdiagnosed with COPD when using the lower limit of the normal range as a diagnostic reference.METHODS:Subjects with COPD diagnosed by a pulmonologist according to guidelines of the Global Initiative for Chronic Obstructive Lung Disease were recruited from October 2016 to April 2018. Overdiagnosed COPD was defined as FEV1/FVC that meets the criterion of the 0.7 fixed ratio but not the the lower limit of the normal range criterion. Spirometry and questionnaires were performed by eligible subjects.RESULTS:Of the 513 subjects included in the final analysis, 20 (3.9%) were overdiagnosed when using the lower limit of the normal range as the diagnostic reference. The subjects who were overdiagnosed were older, weighed more, had better lung function, lower modified Medical British Research Council scores, and higher St. George's Respiratory Questionnaire and 36-item Short Form Survey scores than the subjects who were correctly diagnosed. Older age, heavier weight, exposure to cooking oil fumes, or a new-built or newly renovated home were associated with an increased risk of overdiagnosis of COPD (age adjusted odds ratio (OR) 1.17, 95% CI 1.09–1.26; weight adjusted OR 1.08, 95% CI 1.03–1.13; exposure to cooking oil fumes adjusted OR 3.00, 95% CI, 1.04–8.68; exposure to new-built or newly renovated home adjusted OR 10.88, 95% CI 1.46–80.87.CONCLUSIONS:The subjects with overdiagnosed COPD had a better health status and lung function than the subjects who were correctly diagnosed. Older age, heavier weight, and exposure to cooking oil fumes or a new-built or newly renovated home were factors associated with the overdiagnosis of COPD. These findings may help reduce overdiagnosis of COPD.

The millennium bug is back with a vengeance, after programmers in the 1990s simply pushed the problem back by 20 years

McDonald's is opening (some of) its doors next week, but if you want a bank holiday Big Mac fix, here's how.

The first US woman to spacewalk flew on three shuttle missions and says nothing beats space flight – but her proudest achievement is helping to repair the Hubble Space Telescope

For years, those living and working in nursing and retirement homes across the country have struggled as overburdened caregivers tried to maintain a basic level of care and dignity for aging and ailing Canadians.

Virgin Media customers are still complaining about issues with their broadband despite the provider saying the issue has been fixed.

Twitter users have been complaining that their direct messaging function (DMs) is down.

As Elon Musk's Starlink and Jeff Bezos's Project Kuiper race to create high-speed internet using satellites orbiting Earth, there's a small problem that could get in the way: debris. From dead spacecraft that have been around since the dawn of the space age to flecks of paint smashing windows on the International Space Station, rubbish is clogging up our orbits. And with objects moving as fast as 15,500mph (25,000 kmph), the satellite services we've come to depend on are at constant risk of collision. So how to fix the problem with junk in space? Ian Anderson investigates

https://www.ebay.com/itm/Microsoft-Xbox-One-X-1TB-Black-Console-as-is-for-repair-or-parts-only/264227168298

YMMV obviously--I ordered two of these a month ago and they have been running fine for me.  All I had to do was reinstall the newest system update and they have both been fine with no issues.  One system's issue noted was "freezes" and the other was "no video". 

It says he has only 2 in stock, but I bought two a while back and the listing has remained active for the entire time with stock available, so he probably leaves the number low to keep demand going. This is probably a bulk buyer who doesn't extensively troubleshoot the systems.  I am not affiliated with the seller.  Cosmetically, the systems are nice enough to trade in without taking a refurb fee when stores re-open for business.

OTTAWA - For years, those living and working in nursing and retirement homes across the country have struggled as overburdened caregivers tried to maintain a basic level of care and dignity for aging and ailing Canadians. It happened behind closed doors, said Carole Estabrooks, a professor in

While the data suggests long-term care homes across the globe have suffered unduly from COVID-19, residents in Canada's system seem to be suffering more than others.

Visual challenges remain before autonomous cars are ready for the masses.

Thousands of drug convictions have been thrown out

With comedy festivals cancelled around the world, Amazon Prime is releasing 10 original Australian standup specials to tide you over. Filmed at Melbourne's Malthouse theatre during the Before Times, the biweekly series has featured names like Celia Pacquola, Zoë Coombs Marr and Dilruk Jayasinha – with Tom Gleeson, Anne Edmonds and Tom Walker coming up soon. A few minutes of each is being published exclusively on Guardian Australia, and this week we have Judith Lucy, from her 2019 tour Judith Lucy vs Men

• Two Amazon Original standup specials will be released each week from 10 April. Amazon Prime is offering a 30-day free trial here

With comedy festivals cancelled around the world, Amazon Prime is releasing 10 original Australian standup specials to tide you over. Filmed at Melbourne's Malthouse theatre during the Before Times, the biweekly series has featured names like Celia Pacquola, Zoë Coombs Marr and Dilruk Jayasinha – with Tom Gleeson and Anne Edmonds  coming up soon. A few minutes of each is being published exclusively on Guardian Australia, and this week we have the exceptionally odd new show from Tom Walker, which was directed by Zoë Coombs Marr.

• The full version of Tom Walker's Very Very is released today. Amazon Prime is offering a 30-day free trial here

With comedy festivals cancelled around the world due to the coronavirus crisis, Amazon Prime is releasing 10 original Australian standup specials to tide you over. The biweekly series was filmed at Melbourne's Malthouse Theatre and has featured Celia Pacquola, Zoë Coombs Marr and Dilruk Jayasinha. A few minutes of each is being published exclusively by Guardian Australia and this week we have eventual Gold Logie winner Tom Gleeson's show Joy. Come to hear about the disgusting wonders of parenting; stay for the killer punchline 

• The full version of Tom Gleeson's Joy is out now. Amazon Prime is offering a 30-day free trial here

Premier League clubs remain committed to finishing the 2019/20 season following an online meeting today, with a potential deadline of June 30 not discussed.

Champions League dates for the remainder of the European calendar are set to be confirmed by Uefa, according to reports in Italy.

The government have been urged to conduct an investigation into links between Liverpool hosting a Champions League meeting with Atletico Madrid and a spike in cases of coronavirus in the city.

The Premier League are in talks with several UK rights holders over how to divvy up the remaining fixtures as part of preparations for the top flight's return behind closed doors.

Premier League clubs are working towards a restart as the whole sport battles with the coronavirus pandemic.

Macclesfield Town have been hit with an immediate seven-point deduction for failing to fulfil a fixture along with non-payment of their players.

After nearly two months without football in the major European leagues due to the coronavirus pandemic, the German Bundesliga will finally return on Saturday, May 16.

Football fans will have the chance to embark upon a nostalgic journey over the next few weeks as ITV screen the 1996 European Championships in their entirety.

And they don't all live in Silicon Valley, either.

Two-thirds of working mums and dads are struggling to look after themselves physically and mentally, according to a new report. The findings are pretty depressing. But what can parents actually do about it?

Jabari Johnson celebrates an important victory over evil.

Microsoft will repair Surface Laptop 3 screens for free, particularly those that suddenly cracked for no discernible reason. Surface owners have been posting online about discovering hairline cracks on their new laptops’ display over the past few mon...

Chargers defensive coordinator Gus Bradley said an emphasis will be placed on pressuring quarterbacks this season, making offenses susceptible to game-changing mistakes.

The competition and consumer watchdog has launched an inquiry into whether tractor manufacturers are failing farmers who want the right to repair their own machinery.

From today, new masks and protective boxes are being shipped out to Australian medical staff to help protect them while treating coronavirus patients — and they're coming from an unlikely source.

Supercar engineers are taking their skills from the racetrack to the ICU ward by creating a ventilator prototype to help during the coronavirus crisis.

A Test cricketer driving a Formula 1 car, virtual horse racing at Aintree and a husband tripping over computer cords while his wife is in second place in an online triathlon — here's how athletes are coping online during the coronavirus.

Five men are charged with match fixing offences — some of which carry penalties of up to 10 years in jail — as part of the first Australian criminal investigation into esports.

Health news and commentary from around the Web gathered by the ALLMedPage Today staff

Three air cargo carriers, LAN Cargo S.A. (LAN Cargo), Aerolinhas Brasileiras S.A. (ABSA), and EL AL Israel Airlines Ltd. (EL AL), have each agreed to plead guilty and pay criminal fines totaling $124.7 million for their roles in a conspiracy to fix prices in the air cargo industry.

A federal grand jury in San Francisco returned an indictment against two former executives from Chunghwa Picture Tubes Ltd. (Chunghwa) and one former executive from LG Display Co. Ltd. (LG) for their participation in a global conspiracy to fix prices of Thin Film Transistor-Liquid Crystal Display (TFT-LCD) panels.

A federal grand jury in San Francisco today returned a two-count indictment against the former Chairman and Chief Executive Officer of Chunghwa Picture Tubes Ltd. for his participation in global conspiracies to fix prices of two types of cathode ray tubes (CRTs) used in computer monitors and televisions.

Japanese electronics manufacturer Hitachi Displays Ltd., agreed to plead guilty and pay a $31 million fine for its role in a conspiracy to fix prices in the sale of Thin Film Transistor-Liquid Crystal Display panels (TFT-LCD) sold to Dell Inc.

A federal grand jury in San Francisco returned an indictment today charging an executive at Hitachi Displays Ltd. with participating in a global conspiracy to fix the prices of Thin Film Transistor-Liquid Crystal Display (TFT-LCD) panels sold to Dell Inc.

Three international airline companies—Luxembourg-based Cargolux Airlines International S.A., Japan-based Nippon Cargo Airlines Co. Ltd. (NCA), and Korea-based Asiana Airlines Inc.—have each agreed to plead guilty and pay criminal fines totaling $214 million for conspiring to fix prices in the air cargo industry. In addition, Asiana was charged with fixing the passenger fares charged on flights from the United States to Korea.

A high-level Korean executive from LG Display Co. Ltd. (LG) has agreed to plead guilty and serve a year in jail in the United States for participating in a global conspiracy to fix prices in the sale of Thin Film Transistor-Liquid Crystal Display (TFT-LCD) panels.

A Dutch citizen and executive of Martinair Holland N.V. (Martinair) has agreed to plead guilty, serve time in jail and pay a criminal fine for participating in a conspiracy to fix cargo rates for international air shipments. Including today’s charge, a total of 15 airlines and four executives have pleaded guilty or agreed to plead guilty in the Justice Department’s ongoing investigation into price fixing in the air transportation industry.

A federal grand jury in San Francisco has returned an indictment against a former executive of a large Taiwanese color display tube (CDT) manufacturing company for participating in a global conspiracy to fix prices of CDTs, a type of cathode ray tube used in computer monitors and other specialized applications.

Japanese electronics manufacturer Epson Imaging Devices Corporation (Epson) agreed to plead guilty and pay a $26 million criminal fine for its role in a conspiracy to fix prices in the sale of Thin Film Transistor-Liquid Crystal Display panels (TFT-LCD) sold to Motorola Inc.

Companies directly affected by the LCD price-fixing conspiracy are some of the largest computer and television manufacturers in the world, including Apple, Dell and HP.

Parker ITR S.r.l. has agreed to plead guilty and to pay a $2.29 million criminal fine for participating in a conspiracy to rig bids, fix prices and allocate market shares of marine hose.

A federal grand jury in San Francisco today returned an indictment against a former executive of a large Taiwan-based color display tube (CDT) manufacturing company for his participation in a global conspiracy to fix prices of CDTs, a type of cathode ray tube used in computer monitors and other specialized applications, the Department of Justice announced.

A former executive of an Iowa ready-mix concrete company has agreed to plead guilty and serve 19 months in jail for participating in three separate conspiracies to fix prices and rig bids for the sales of ready-mix concrete.