disease Dr. Nikhil Bhayani Celebrated for Dedication to the Field of Infectious Disease Medicine By www.24-7pressrelease.com Published On :: Mon, 30 Sep 2019 07:00:00 GMT Dr. Bhayani lends years of expertise to his work as a physician advisor with Texas Health Resources Full Article
disease Baby Aspirin May Be Beneficial for Parkinson's Disease By www.24-7pressrelease.com Published On :: Mon, 10 Sep 2018 07:00:00 GMT Currently, no effective drug is available to halt the progression of Parkinson's disease. Scientists have shown that low-dose aspirin may help Parkinson patients. Full Article
disease New Tool Helps Clinicians More Accurately Predict Outcomes for Patients with Severe Respiratory Disease By www.24-7pressrelease.com Published On :: Thu, 30 May 2019 07:00:00 GMT New Intermountain Healthcare Study Finds Computer-Based Predictive Tool More Accurately Forecasts Outcomes for Respiratory Patients Helping Clinicians Provide Best Course of Care Full Article
disease How Can We Fight COVID-19 Disease Today? By www.24-7pressrelease.com Published On :: Fri, 24 Apr 2020 07:00:00 GMT Sanitizing and disinfection - are they really a key to COVID-19 elimination? Probably yes says the science. Full Article
disease Huntington Beach Dentist, Dr. Rassouli, Warns about the Unexpected Dangers of Gum Disease By www.24-7pressrelease.com Published On :: Tue, 18 Feb 2020 07:00:00 GMT Dr. Rassouli warns patients about the unknown dangers of gum disease and its link to other health issues including Alzheimer's disease, cardiovascular disease, cancer, and respiratory infections. Full Article
disease Jet Medical Tourism® Cites Major New Research Published by JAMA Network That Says Bariatric Surgery Reduces Heart Disease Risks By www.24-7pressrelease.com Published On :: Tue, 05 May 2020 07:00:00 GMT Severely obese patients often live with the constant fear that they may suffer a heart attack because of their low physical activity, poor metabolism, and the extra pressure on their heart caused by their excessive body weight. Full Article
disease Moirar M. Leveille launches her new book "Mind Your Health, or Mind Your Death - Choose Your Path: A Journey from Autoimmune Disease to Vibrant Health Without Drugs" By www.24-7pressrelease.com Published On :: Sun, 15 Dec 2019 07:00:00 GMT Book Become International Best Seller Full Article
disease Prevent Disease, Enjoy Vibrant Health Through Functional Blood Chemistry Analysis By www.24-7pressrelease.com Published On :: Sat, 04 Apr 2020 07:00:00 GMT Kristin Grayce McGary's new book "Know Your Blood, Know Your Health" launches April 7, 2020 Full Article
disease Egyptian Painter Arafaat to Donate the Proceeds of a 1-Million Dollars Artwork Painting to the Chest Diseases Hospital in Cairo Egypt to Help Handle the Corona Virus Cases By www.24-7pressrelease.com Published On :: Mon, 30 Mar 2020 07:00:00 GMT Egyptian painter Arafaat participates #ArtCanHelp cause on social media for Corona virus solidarity Full Article
disease Composer Donates "Wash Your Hands" 20-Second Jingle to Center for Disease Control (CDC) By www.24-7pressrelease.com Published On :: Sun, 15 Mar 2020 07:00:00 GMT Innovator & Multi-Genre Composer, Blythe Abigail 黄淑仁 Schulte, Gets Inspiration from Public-Private Partnerships Amid COVID-19 Crisis Full Article
disease Drug Repurposing Study Discovers that Natural Supplement Diosmin For Varicose Veins May Treat COVID-19 Disease Better than 97% of Antiviral Drugs By www.24-7pressrelease.com Published On :: Tue, 21 Apr 2020 07:00:00 GMT A computational study of 4,600 drugs indicates that approved drugs were less effective than non-approved drugs when binding to a COVID-19 protein. In addition, Diosmin, a non-prescription natural supplement bound better than 99% of drugs considered. Full Article
disease How AI Can Help Manage Infectious Diseases By feedproxy.google.com Published On :: Tue, 28 Apr 2020 14:00:07 +0000 With the capability to analyze huge amounts of data, including medical information, human behavior patterns, and environmental conditions, big data tools can be invaluable in dealing with deadly outbreaks. Full Article 2020 Apr Tutorials Overviews AI Coronavirus Covid-19 Healthcare
disease Discretion in Enforcement when Considering an Employer's Good Faith Efforts During the Coronavirus Disease 2019 (COVID-19) Pandemic By www.necanet.org Published On :: Fri, 17 Apr 2020 18:27:39 Z In light of the coronavirus disease 2019 (COVID-19) pandemic, OSHA understands that some employers may face difficulties complying with OSHA standards due to the ongoing health emergency. Business closures and other restrictions and limitations may also preclude employee participation in training even when trainers are available. In other situations, access to medical testing facilities may be limited or suspended. Full Article Home Page
disease Amit Shah dismisses rumours about his health, says he is not suffering from any disease By economictimes.indiatimes.com Published On :: 2020-05-09T16:40:11+05:30 Amit Shah dismisses rumours about his health, says he is not suffering from any disease Full Article
disease Taking Hot Baths Every Day is Linked to Lower Risk of Stroke or Heart Disease By www.goodnewsnetwork.org Published On :: Wed, 08 Apr 2020 16:55:59 +0000 Similarly to how sauna bathing has been linked to some surprising health benefits, this new study says that regularly taking hot baths is good for you too. The post Taking Hot Baths Every Day is Linked to Lower Risk of Stroke or Heart Disease appeared first on Good News Network. Full Article Health Science Japan At Home Lifestyle Research Wellness NewsCred
disease New Alzheimer’s Nasal Spray Shown to Reduce Proteins Which Cause the Disease in Mice By www.goodnewsnetwork.org Published On :: Sun, 26 Apr 2020 18:40:53 +0000 Kyoto University researchers said the vaccine for Alzheimer’s was effective and was also shown to have zero side effects observed in the mice. The post New Alzheimer’s Nasal Spray Shown to Reduce Proteins Which Cause the Disease in Mice appeared first on Good News Network. Full Article Health Science Japan Alzheimers Research Breakthroughs Brain Vaccine NewsCred Medical
disease New Intermittent Fasting Program Shown to Suppress Cancer and Metabolic Disease in Mice and Humans By www.goodnewsnetwork.org Published On :: Sat, 02 May 2020 21:29:20 +0000 This new research has outlined yet another benefit to intermittent fasting—that may arise from the time you eat, rather than what you eat. The post New Intermittent Fasting Program Shown to Suppress Cancer and Metabolic Disease in Mice and Humans appeared first on Good News Network. Full Article Health Science Diet Disease Research Exercise Wellness Fitness NewsCred Medical
disease Northwest forest plants defeat pests and diseases! By www.fs.fed.us Published On :: Wed., 01 Mar 2017 12:00:00 PST Societies use biologically active chemicals as medicines and pesticides to protect human and agricultural health. But widespread use of synthetic compounds raises concerns about their safety, and resistance development in targeted pests. Full Article
disease Mum who battled cancer three times vows to 'never let terrible disease' beat her By www.chroniclelive.co.uk Published On :: Sat, 9 May 2020 15:00:00 +0000 Jackie Pexton, who is part of the Macmillian Toon Angels, has raised over £52,000 to show her support for the charity that has been a lifeline for her Full Article North East News
disease Better options needed for children at higher risk of premature heart disease By newsroom.heart.org Published On :: Mon, 25 Feb 2019 10:00:00 GMT Statement Highlights: New developments in identifying and treating the increased risk of premature heart disease in children and teens with certain medical conditions associated with increased cardiovascular risk are discussed in a scientific statement from the American Heart Association. Obesity and severe obesity are now considered significant risk factors for an increased risk of cardiovascular disease in children and teens. Full Article
disease People living with HIV face premature heart disease and barriers to care By newsroom.heart.org Published On :: Mon, 03 Jun 2019 09:00:00 GMT Statement Highlights: People living with HIV face a higher risk of developing diseases of the heart and blood vessels compared to people without the disease. Seventy-five percent of people living with HIV are over age 45 and face significant health challenges at earlier ages than people who don’t have HIV. Full Article
disease Work-related stress linked to increased risk for peripheral artery disease By newsroom.heart.org Published On :: Tue, 28 Apr 2020 09:00:00 GMT Research Highlights: People who reported work-related stress were more likely to be hospitalized for treatment of peripheral artery disease compared to those who did not report work-related stress. Work-related stress, or job strain, refers to... Full Article
disease Kids with Kawasaki disease symptoms possibly linked to COVID-19; coronavirus infection leading to critical illness in children remains very infrequent By newsroom.heart.org Published On :: Wed, 06 May 2020 20:17:33 GMT Full Article
disease Better sleep habits may help reduce heart disease risk and aid in weight loss By newsroom.heart.org Published On :: Tue, 03 Mar 2020 21:00:00 GMT Research Highlights: People who had the best heart health, defined as having healthy sleep in addition to meeting the AHA Life Simple 7, were less likely to have a diagnosis of a heart disease and were less likely to develop heart disease in the ... Full Article
disease Heart disease risk profiles differ widely among African Americans, blacks from the Caribbean and African immigrants By newsroom.heart.org Published On :: Wed, 04 Mar 2020 21:00:00 GMT Research Highlights: Black immigrants from Africa and from the Caribbean differ from U.S.-born blacks in rates of high blood pressure, diabetes, smoking and overweight/obesity. The research supports a more detailed look at black populations and the... Full Article
disease Consuming more olive oil associated with less heart disease in Americans By newsroom.heart.org Published On :: Thu, 05 Mar 2020 21:00:00 GMT Research Highlights: Consuming more than half a tablespoon of olive oil daily was associated with a 15% lower risk of having any type of cardiovascular disease and a 21% lower risk of having coronary heart disease. Replacing one teaspoon of butter, ... Full Article
disease Patient perspective: Living with type 2 diabetes and heart disease amid COVID-19 By newsroom.heart.org Published On :: Thu, 23 Apr 2020 14:15:00 GMT DALLAS and ARLINGTON, April 23, 2020 — As emerging science around COVID-19 highlights elevated danger for people with diabetes, heart disease and stroke[1], the American Heart Association and the American Diabetes Association urge people living with type... Full Article
disease The American Heart Association asks your help to support the 120M people in the U.S. living with cardiovascular disease who may be at higher risk of complications from COVID-19 By newsroom.heart.org Published On :: Mon, 04 May 2020 17:30:00 GMT DALLAS, May 4, 2020 — Tomorrow, on #GivingTuesdayNow, a global day of philanthropic action to address the COVID-19 pandemic, the American Heart Association – the leading global public health organization devoted to a world of longer healthier lives – is... Full Article
disease Diagnosis of Coronavirus Disease 2019 (COVID-19) with Structured Latent Multi-View Representation Learning. (arXiv:2005.03227v1 [eess.IV]) By arxiv.org Published On :: Recently, the outbreak of Coronavirus Disease 2019 (COVID-19) has spread rapidly across the world. Due to the large number of affected patients and heavy labor for doctors, computer-aided diagnosis with machine learning algorithm is urgently needed, and could largely reduce the efforts of clinicians and accelerate the diagnosis process. Chest computed tomography (CT) has been recognized as an informative tool for diagnosis of the disease. In this study, we propose to conduct the diagnosis of COVID-19 with a series of features extracted from CT images. To fully explore multiple features describing CT images from different views, a unified latent representation is learned which can completely encode information from different aspects of features and is endowed with promising class structure for separability. Specifically, the completeness is guaranteed with a group of backward neural networks (each for one type of features), while by using class labels the representation is enforced to be compact within COVID-19/community-acquired pneumonia (CAP) and also a large margin is guaranteed between different types of pneumonia. In this way, our model can well avoid overfitting compared to the case of directly projecting highdimensional features into classes. Extensive experimental results show that the proposed method outperforms all comparison methods, and rather stable performances are observed when varying the numbers of training data. Full Article
disease How climate change is contributing to skyrocketing rates of infectious disease By www.inlander.com Published On :: Fri, 08 May 2020 17:27:54 -0700 A catastrophic loss in biodiversity, reckless destruction of wildland and warming temperatures have allowed disease to explode. Ignoring the connection between climate change and pandemics would be “dangerous delusion,” one scientist said. The scientists who study how diseases emerge in a changing environment knew this moment was coming.… Full Article News/Nation & World
disease Nitrate esters and their use for the treatment of muscle and muscle related diseases By www.freepatentsonline.com Published On :: Tue, 05 May 2015 08:00:00 EDT Alkyl nitrate ester compounds are provided for the delivery of nitric oxide to targeted muscle tissues, and in particular, to normal and dystrophic muscles. In one aspect, nitrate ester compounds are provided having the following formula: wherein, R1 is ONO2, CH2ONO2, CnH2n+1OH, CnH2n+1OH, or CH2CH2CH3, or H;R2 is ONO2, CH2ONO2, Cn'H2n'+1OH, Cn'H2n'+1OH, CH2CH2CH3 or H; andR3 is ONO2, CH2ONO2, Cn'″H2n″+1OH, Cn″H2n″+1OH, CH2CH2CH3 or H; wherein n is an integer from 0 to 9, n' is an integer from 0 to 9, and n″ is an integer from 0 to 9, and n+n'+n″≦9, and wherein at least one of R1, R2, and R3 is an ester nitrate selected from the group consisting of ONO2, CH2ONO2, and combinations thereof. Full Article
disease Tumor and infectious disease therapeutic compositions By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A pharmaceutical composition comprising lectins is anti-tumorigenic and anti-viral, bacterial or protozoan. The composition, termed BiOmune is also useful for imaging, diagnosis and therapy of cancer. Full Article
disease Cytosine analogue, a method of preparation of a cytosine analogue, a DNA methyltransferase 1 inhibitor, a method for DNA methylation inhibition, the use of the analogue in the treatment of diseases associated with deviations from normal DNA methylation By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT A cytosine analog, a method of preparation of a cytosine analog, a DNA methyltransferase 1 inhibitor, and a method for DNA methylation inhibition, is provided for the treatment of diseases associated with deviations from normal DNA methylation. The analog of cytosine may be comprised of 1, N4, 5 and 6-substituted derivatives of cytosine or 5,6-dihydrocytosine, wherein the analog can be described by the chemical formula where R1 is H, R3, R4, 2'-deoxyribosyl, R4 is alkyl or aryl, X is N or C, wherein if X in the analog of formula I is N, then R5 is no substituent and if X in the analog of formula I and/or II is C or if X in the analog of formula II is N, then R5 and R6 are independently alkyl, aryl, hydroxyalkyl, aminoalkyl, hydroxyl, carboxyl, amino group, alkoxyl, aryloxyl, aminoalkyl, aminoaryl, thio group, sulfonyl, sulfinyl or halogen. Full Article
disease Delayed-release glucocorticoid treatment of rheumatoid disease By www.freepatentsonline.com Published On :: Tue, 30 Dec 2014 08:00:00 EST Provided are methods for the treatment of a rheumatic disease, such as rheumatoid arthritis, ankylosating spondylitis and/or polymyalgia rheumatic, by administering a delayed-release dosage form of a glucocorticoid to a subject in need thereof wherein the treatment is administered once daily for at least about two weeks. Also provided are methods for the treatment of osteoarthritis by administering a delayed-release dosage form of a glucocorticoid to a subject in need thereof wherein the treatment is administered once daily for at least about two weeks. Full Article
disease Treatment of muscle disease characterized by insulin resistance By www.freepatentsonline.com Published On :: Tue, 31 Mar 2015 08:00:00 EDT It is reported herein that certain muscle diseases and conditions, including forms of muscular dystrophy, are characterized by impaired insulin-dependent signaling in the muscle tissue, in essence, a form of insulin resistance. The present disclosure relates to therapeutic agents, compositions and methods for treating a muscle disease or condition characterized by impaired insulin-dependent signaling by targeting components of the defective insulin signaling pathway. The disease or condition may be treated by administering a therapeutic agent that activates the insulin signaling pathway, in particular, therapeutic agents that act post-insulin receptor to modulate intracellular effector molecules. An exemplary modulator is metformin. Metformin may be administered alone or may be coadministered with another therapeutic agent for treating the muscle disease or condition, such as a corticosteroid. Full Article
disease Molecules that induce disease resistance and improve growth in plants By www.freepatentsonline.com Published On :: Tue, 05 May 2015 08:00:00 EDT Described herein are methods and compositions for enhancing pathogen immunity in plants and improving plant growth. Full Article
disease Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT The methods described herein enable the evaluation of compounds on subjects to assess their therapeutic efficacy or toxic effects. The target of analysis is the underlying biochemical process or processes (i.e., metabolic process) thought to be involved in disease pathogenesis. Molecular flux rates within the one or more biochemical processes serve as biomarkers and are quantitated and compared with the molecular flux rates (i.e., biomarker) from control subjects (i.e., subjects not exposed to the compounds). Any change in the biomarker in the subject relative to the biomarker in the control subject provides information to evaluate therapeutic efficacy of an administered drug or a toxic effect and to develop the compound further if desired. In one aspect of the invention, stable isotope-labeled substrate molecules are administered to a subject and the label is incorporated into targeted molecules in a manner that reveals molecular flux rates through metabolic pathways of interest. Full Article
disease Skull-focused RF-based stimulation apparatus, system and method for treating patients with Alzheimer's disease or other dementia By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT The portable, wearable, proximal Alzheimer's disease treatment invention is based upon creating an RF field of particular frequencies and intensities that are applied to the patient's head. To accomplish the aforementioned disease treatment functionality, a system was invented comprising a network of antennas connected to an RF generator via a feedline connector. The invention also provides methods for using measurements to monitor and manage the effectiveness of an ongoing disease treatment regimen, and databases which contain information about measurements, variables, and their relationships to clinical outcome. Full Article
disease Modalities for the treatment of degenerative diseases of the retina By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment epithelium (RPE) cells and other retinal progenitor cells. Full Article
disease Nonhuman mammal whose mtDNA is from a nonhuman mammal resistant to a selected disease or disorder and whose nDNA is from a nonhuman donor mammal more susceptible to the selected disease or disorder By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Provided herein are mitochondrial-nuclear exchanged cells and animals comprising mitochondrial DNA (mtDNA) from one subject and nuclear DNA (nDNA) from a different subject. Methods for producing a mitochondrial-nuclear exchanged animal and animals made by the methods are provided. Also provided are methods of screening for agents useful for treating a disease or disorder using mitochondrial-nuclear exchanged animals or cells, tissues or organs thereof. Full Article
disease BCL-2 selective apoptosis-inducing agents for the treatment of cancer and immune diseases By www.freepatentsonline.com Published On :: Tue, 07 Jul 2015 08:00:00 EDT Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti-apoptotic Bcl-2 protein. Full Article
disease Methods for treating steatotic disease By www.freepatentsonline.com Published On :: Tue, 26 May 2015 08:00:00 EDT Methods for treating fatty liver disease, e.g., hepatic steatosis, using peptide fragments of the C-terminal end of glucagon-like peptide-1 (GLP-1), e.g., GLP-1(28-36). Full Article
disease Method for the treatment of automimmune diseases comprising administering rapamycin and IL-10 By www.freepatentsonline.com Published On :: Tue, 11 Dec 2012 08:00:00 EST The invention discloses a combined preparation containing IL-10 and rapamycin, able to induce immunosuppression and antigen-specific immune tolerance, and the use thereof in the treatment of diseases involving an excessive, dysfunctional or uncontrolled immune responses mediated by T cells. Full Article
disease Method of detecting pancreatic disease and pancreas testing kit By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A pancreatic disease is tested for with high sensitivity even with simple equipment and a simple procedure. Provided is a method of detecting pancreatic disease including detecting a concentration of S100P in at least one of a pancreatic juice and a body fluid containing pancreatic juice collected from a test subject by immunochromatography. Additionally provided is a pancreas testing kit including an immunochromatography device that holds an anti-S100P antibody and a collection vessel that retains a protease inhibitor that inhibits an activity of a protease contained in the pancreatic juice. Full Article
disease Compositions for diagnosis and therapy of diseases associated with aberrant expression of futrins (R-spondins) and/or Wnt By www.freepatentsonline.com Published On :: Tue, 14 Jul 2015 08:00:00 EDT The present invention relates to a composition useful for the diagnosis of diseases associated with aberrant expression of the genes encoding the secreted proteins Futrin 1, 2, 3 and/or 4(=R-Spondin 2, 3, 1 and 4, respectively), e.g. in connection with tumors or diseases of the muscle, kidneys or bones. The present invention also relates to a pharmaceutical composition containing a compound which is capable of modifying (a) the expression of the gene encoding Futrin 1, 2, 3 and/or 4 or (b) the activity of the Futrin 1, 2, 3 and/or 4 protein. Full Article
disease System and methods for detecting liver disease By www.freepatentsonline.com Published On :: Tue, 19 May 2015 08:00:00 EDT A noninvasive, quantitative imaging technique is presented for detecting and diagnosing liver disease, such as cirrhosis. The technique includes: capturing scan data from a subject using computed tomography or another type of imaging method and extracting image data representing the liver from the scan data. Various measures of the liver may be obtained from image data and then used to compute random variables of a statistical model, where the model is predictive of a medical condition of the liver and comprised of random variables that are indicative of at least one of a shape or texture of the liver. Output from the statistical model provides an indication of an undesirable condition of the liver. Full Article
disease Towel tags to permit minimizing the use of water and detergent during washing and minimizing wear and tear of towels, the spread of germs and diseases between towel users, and minimizing the use of energy, and saving money By www.freepatentsonline.com Published On :: Tue, 21 Apr 2015 08:00:00 EDT Towel tags to permit minimizing the use of water and detergent during washing and minimizing wear and tear of towels, the spread of germs and diseases between towel users, and minimizing the use of energy, and saving money. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. §1.72(b). As stated in 37 C.F.R. §1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. Any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner. Full Article
disease PAENIBACILLUS LARVAE TREATMENT WITH PHAGE LYSIN FOR AMERICAN FOULBROOD DISEASE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Materials and methods for treating and preventing American Foulbrood disease in honeybees, such as materials and methods for using phage lysin enzymes to lyse Paenibacillus larvae, are provided herein. Full Article
disease COMBINATION OF AN OXIDANT, A PHOTOSENSITIZER AND A WOUND HEALING AGENT FOR ORAL DISINFECTION AND TREATMENT OF ORAL DISEASE By www.freepatentsonline.com Published On :: Thu, 08 Jun 2017 08:00:00 EDT The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmacologically acceptable carrier. Full Article
disease BIOSYNCHRONOUS TRANSDERMAL DRUG DELIVERY FOR LONGEVITY, ANTI-AGING, FATIGUE MANAGEMENT, OBESITY, WEIGHT LOSS, WEIGHT MANAGEMENT, DELIVERY OF NUTRACEUTICALS, AND THE TREATMENT OF HYPERGLYCEMIA, ALZHEIMER'S DISEASE, SLEEP DISORDERS, PARKINSON'S DISE By www.freepatentsonline.com Published On :: Thu, 29 Jun 2017 08:00:00 EDT Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible. An automated, pre-programmable transdermal administration system is used to provide pulsed doses of medications, pharmaceuticals, hormones, neuropeptides, anorexigens, pro-drugs, stimulants, nutraceuticals, phytochemicals, phytonutrients, enzymes, antioxidants, essential oils, fatty acids, minerals, vitamins, amino acids, coenzymes, or other physiological active ingredient or precursor. The system can utilize a pump, pressurized reservoir, a system for removing depleted carrier solution, or other modulated dispensing actuator, in conjunction with porous membranes or micro-fabricated structures. Full Article