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Union Finance Minister Nirmala Sitharaman meets AIIB Board of Directors in Delhi




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Automated electrosynthesis reaction mining with multimodal large language models (MLLMs)

Chem. Sci., 2024, 15,17881-17891
DOI: 10.1039/D4SC04630G, Edge Article
Open Access
Shi Xuan Leong, Sergio Pablo-García, Zijian Zhang, Alán Aspuru-Guzik
Leveraging multimodal large language models (MLLMs) to process multimodal data inputs and complex inter-modality data dependencies for automated (electro)chemical data mining from scientific literature.
The content of this RSS Feed (c) The Royal Society of Chemistry




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The Effect of gem-Difluorination on the Conformation and Properties of a Model Macrocyclic System

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05424E, Edge Article
Open Access
Laurent Knerr, Thomas Cogswell, Marie. Ahlqvist, Richard James Lewis, Anneli Nordqvist, Christian Sköld
Conformational control of drug candidates to engineer improved potency and ADME properties is an ongoing area of research. Macrocyclic rings tend to offer a greater degree of rigidity than non-cyclised...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Selective lignin depolymerization via transfer hydrogenolysis using Pd/hydrotalcite catalysts: model compounds to whole biomass

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC03942D, Edge Article
Open Access
Darren Dolan, Rebekah Brucato, Christopher William Reid, Adam F. Lee, Karen Wilson, Adelina M Voutchkova-Kostal
Cleavage of lignin ether bonds via transfer hydrogenolysis is a promising route to valorize lignin, but processes that use mild reaction conditions and exploit renewable hydrogen donor solvents (rather than...
The content of this RSS Feed (c) The Royal Society of Chemistry




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PharmacoNet: deep learning-guided pharmacophore modeling for ultra-large-scale virtual screening

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC04854G, Edge Article
Open Access
Seonghwan Seo, Woo Youn Kim
PharmacoNet is developed for virtual screening, including deep learning-guided protein-based pharmacophore modeling, a parameterized analytical scoring function, and coarse-grained pose alignment. It is extremely fast yet reasonably accurate.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Strain-induced charge delocalization achieves ultralow exciton binding energy toward efficient photocatalysis

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05873A, Edge Article
Open Access
Junyuan Duan, Yinghe Zhao, Yu Wu, Youwen Liu, Junnian Chen, Ruoou Yang, Jiazhao Huang, Chuanqi Luo, Mao Wu, Xiaodong Zheng, Pengyu Li, Xueliang Jiang, Jianguo Guan, Tianyou Zhai
A novel approach of strain-induced charge delocalization is developed to significantly reduce the exciton binding energy of Ta2O5 nanorods to below ambient thermal energy, leading to a remarkable enhancement in photocatalytic hydrogen evolution.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Delocalization error poisons the density-functional many-body expansion

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05955G, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Dustin R. Broderick, John M. Herbert
Self-interaction error leads to runaway error accumulation when density functional theory is used in conjunction with the many-body expansion.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Edelweiss Business Cycle NFO: Should you invest?

The new fund seeks to combine multiple factors to make the most of business cycles




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20 landmark verdicts delivered by CJI Chandrachud




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India warns 'least common denominator' model of UNSC reforms could derail major change




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India warns 'least common denominator' model of UNSC reforms could derail major change




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Efficient numerical modelling of magnetophoresis in millifluidic systems

Lab Chip, 2024, 24,5009-5019
DOI: 10.1039/D4LC00595C, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Johannes Soika, Tobias Wanninger, Patrick Muschak, Anja Schnell, Sebastian P. Schwaminger, Sonja Berensmeier, Markus Zimmermann
Analytical system descriptions enable efficient 3D magnetophoresis modeling, where dimensions and fluid profile choices significantly impact results.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Exploring cancer-associated fibroblast-induced resistance to tyrosine kinase inhibitors in hepatoma cells using a liver-on-a-chip model

Lab Chip, 2024, 24,5043-5054
DOI: 10.1039/D4LC00624K, Paper
Madhu Shree Poddar, Yu-De Chu, Gaurav Pendharkar, Cheng-Hsien Liu, Chau-Ting Yeh
3D liver-on-a-chip reveals AHSG and CLEC3B to mediate cancer-associated fibroblast-induced resistance to TKIs in hepatoma cells.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Applying Low Levels of Strain to Model Nascent Phenomenon of Retinal Pathologies

Lab Chip, 2024, Accepted Manuscript
DOI: 10.1039/D4LC00205A, Paper
Chase Paterson, Elizabeth Vargis
Age-related macular degeneration (AMD) is a leading cause of vision loss in the elderly. A better understanding of the mechanisms of the disease, especially at early stages, could elucidate new...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: Deciphering hepatoma cell resistance to tyrosine kinase inhibitors: insights from a Liver-on-a-Chip model unveiling tumor endothelial cell mechanisms

Lab Chip, 2024, Advance Article
DOI: 10.1039/D4LC90093F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Madhu Shree Poddar, Yu-De Chu, Chau-Ting Yeh, Cheng-Hsien Liu
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Real-time monitoring of a 3D blood–brain barrier model maturation and integrity with a sensorized microfluidic device

Lab Chip, 2024, 24,5085-5100
DOI: 10.1039/D4LC00633J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Maria Cristina Ceccarelli, Marie Celine Lefevre, Attilio Marino, Francesca Pignatelli, Katarzyna Krukiewicz, Matteo Battaglini, Gianni Ciofani
A new in vitro sensorized model of the blood–brain barrier has been developed and characterized.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Delay in completing work on ferry jetties hits commuters in West Kochi

Irrigation department is reportedly being blamed for the delay in completing dredging at Mattancherry Jetty; delay in renovating the Customs Jetty is causing safety issues, CSML asks contractor to expedite work




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Champions Way primed to deliver in the Governor’s Cup




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Del Aviz, Southern Force, Balmoral, Nyx, Chotipari and Macron excel




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Knotty Charmer primed to deliver in the Rajyotsava Trophy




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Foreign brokerages say BJP’s lower-than-expected victory to delay tough reforms but expect policy continuity

Foreign Brokerages predict fiscal consistency with a populist twist under Modi 3.0




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Consumer Affairs Ministry releases draft guidelines to curb pesky promotional calls, messages

Draft guidelines released by DoCA protect consumers from unsolicited and unwarranted communications business communication




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Govt announces guidelines for funding testing facilities under National Green Hydrogen Mission

With a budget of ₹200 crore till FY26, the scheme aims to support the development of standards and regulatory frameworks in the Green Hydrogen sector.




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On eve of Modi’s Moscow visit, Indo-Russia JV delivers 35,000 AK-203s to Indian Army

The Indo-Russian Rifles Private Ltd, a joint venture between India and Russia, has production facility at Amethi, UP and is expected to manufacture more than 600,000 rifles as per a deal between the two sides




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Govt issues operational guidelines for under PM-Surya Ghar: Muft Bijli Yojana

A total financial outlay of ₹800 crore has been allocated for this component, providing ₹1 crore per selected model solar village, the Ministry said




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Delhi pollution: Tips to protect your lungs as AQI levels rise

Here are some essential tips to help protect your lungs during this pollution surge.




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Delay in getting degree certificates leaves students of Lakshadweep worried




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Yogi Adityanath meets U.P. Governor after Delhi visit, adds fuel to buzz over Cabinet expansion before Lok Sabha polls

The Uttar Pradesh CM’s visit to the Governor’s house assumes significance as he attended the crucial BJP meeting in New Delhi for the general election only a few hours earlier




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Parliamentary Panel highlights significant delays in installation of telemetry systems in critical flood-prone areas

The Committee's report on the performance audit of schemes for flood control and forecasting underscores the need for urgent action to ensure timely and effective flood management




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Delhi coaching centre deaths: High Court to hear plea seeking setting up of panel to probe incident

The plea was mentioned for urgent hearing on July 30 before a bench of Acting Chief Justice Manmohan and Justice Tushar Rao Gedela which said the matter be listed on Wednesday




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Will be injustice to SC communities if internal reservation is delayed by Karnataka government: Basavaraj Bommai

Mr. Bommai was recently honoured by SC community leaders in Bengaluru for recommending internal reservation for SC communities back in 2023




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Tripura's connectivity project with Bangladesh may be delayed: Minister

Opening of Agartala-Akhaura rail link and Maitree bridge got further delayed due to the political turmoil and change in government in Bangladesh; this project was inaugurated by Prime Minister Narendra Modi and then Bangladesh PM Sheikh Hasina in 2023




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MCD starts demolition drive in Bhalswa colony in north-west Delhi

The Municipal Corporation of Delhi on August 13 began a demolition drive in north-west Delhi's Bhalswa Dairy colony; heavy deployment of security personnel has been made at the site




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International hockey set to return to New Delhi after 10 years; veteran players Zafar Iqbal, Harbinder Singh hail Indian team

Mr. Iqbal, a gold medallist at the 1980 Moscow Olympics and captain of the 1982 Asian Games silver-winning Indian team, is hopeful for growth of Indian hockey after the bronze medals in the Tokyo and Paris Olympics.




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It felt nicer to deliver for the team: Divya Deshmukh

The 18-year-old from Nagpur played every 11 rounds at the Olympiad. And she remained unbeaten, winning eight games and drawing three.




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India to push for accountability, fair financing, green credit at COP29: Delegates

The 29th session of the climate change conference of parties (COP29) is being held from November 11-22 in Baku, the capital of Azerbaijan Baku




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New Zealand PM delivers landmark apology to survivors of state abuse

Some 2,00,000 vulnerable New Zealanders were abused in state care in the seven decades since the 1950s, according to an inquiry




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Filestack: A File Uploader and Powerful APIs to Deliver and Transform App Content

[Sponsored] If you’re building an app that requires a lot of user-generated content and media that needs to be processed, tagged, filtered, or otherwise manipulated in real-time, you definitely want a solution that’s fast and seamless and doesn’t get in the way of your app’s primary functionality. Filestack is a service you’ll want to consider. Here’s what Filestack offers:

The post Filestack: A File Uploader and Powerful APIs to Deliver and Transform App Content appeared first on Impressive Webs.




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​Delay and bail: On former Tamil Nadu Minister V. Senthilbalaji’s case

Senthilbalaji’s release on bail was overdue, but he should not be made a Minister




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​Allow for deliberation: On the legitimate demands of Ladakh

The lack of a legislature and regional autonomy in Ladakh has led to the current protests




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Development, biological evaluation, and molecular modelling of some benzene-sulfonamide derivatives as protein tyrosine phosphatase-1B inhibitors for managing diabetes mellitus and associated metabolic disorders

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00594E, Research Article
Nagat Ghareb, Khaled M. Darwish, Mohamed S. Nafie, Ranwa Elrayess, Noha M. Abourobe, Shaimaa A. Fattah, Reem M. Hazem, Eman T. Mehanna, Ranza Elrayess
One benzene-sulfonamide derivative exhibited potent protein tyrosine phosphatase-1B inhibition for managing diabetes mellitus and associated metabolic disorders.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Guidelines issued for fertilizer distribution in Karaikal for samba, thaladi paddy cultivation




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Library to hold Group II-A Mains, Group IV TNPSC model test




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Tiruchi Corporation office expansion plan witnesses more delay




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Association holds protest against delay in Anna University’s staff absorption, promotions




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583: Language Models, AI, and Digital Gardens with Maggie Appleton

Maggie Appleton talks with us about her work at Elicit, working with large and small language models, how humans vet the responses from AI, the discussion around the Soggoth meme in AI, using Discord as UI, what to do if your boss wants AI in your app, and why does she call her blog a digital garden?




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Guidelines for green urbanisation

The Ministry of Urban Development has proposed environmental guidelines for construction projects in urban areas. Nidhi Adlakha reports




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The delicate balance in doctor-patient interaction

How clear communication and accountability in healthcare can significantly improve patient outcomes




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New venture Zerofifty from ad veterans wants to simplify the agency model

ZeroFifty Mediaworks, set up by three ad veterans, wants to bring in Bandra vibes into the agency model




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Delhi women to get monthly stipend of ₹1,000 soon: Kejriwal