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Tottenham news: Mauricio Pochettino believes Spurs could face more disruption over players' futures

The likes of Christian Eriksen and Victor Wanyama were expected to leave in the summer but both have remained in north London, with Pochettino insisting they are in his plans.




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Arsenal and Tottenham ready to battle for Liverpool's Dejan Lovren

The Croatian has fallen behind the likes of Virgil van Dijk and Joe Gomez in the pecking order at Anfield and is looking for the opportunity to secure more first team football.




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16 test positive for COVID-19 in Bihar; total cases now 595

Sixteen more people including two minors from nine districts tested positive for COVID-19 on Saturday, taking the total number of cases to 595 in Bihar, a top health department official said. Seven of the 16 fresh cases are migrant people from other states, Health Departments Principal Secretary Sanjay Kumar said in a tweet. "We are ascertaining their further infection trail," Kumar said. Of the 16 new cases, three each are from Muzaffarpur and Arwal, two each from Begusarai, Munger, Nalanda and one each from Vaishali, Bhojpur, Siwan, Sheikhpura districts, the Principal Secretary said. Five people have died of the disease so far in Bihar which is now left with 272 active cases while 318 have recovered. The number of samples tested so far at seven facilities in Patna, Bhagalpur, Muzaffarpur and Darbhanga is 32,767.




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34 more test positive for COVID-19 in Bihar, total count 629

At least 34 new COVID-19 cases were reported in Bihar, raising the total count in the state to 629, a top health department official said on Sunday. Of the 34, 11 hail from Begusarai, seven each from Saharsa and Madhepura, five, including a woman, from Rohtas, two from Darbhanga and one each from Khagaria and Araria districts, Sanjay Kumar, the principal secretary of the state health department, said. "We are ascertaining the infection trail. These are yesterday's results received late in the night," Kumar said, adding that seven out of 34 patients were minors. Barring Jamui, all 37 districts in the state have reported coronavirus cases. The number of active cases in the state currently stands at 306. Altogether, 318 people have recovered so far. Bihar has witnessed five COVID-19 fatalities -- one each from Rohtas, Munger, Vaishali, East Champaran and Sitamarhi districts. All five of them had pre-existing ailments. Munger has accounted for the maximum number of cases in the ...




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Singapore reports 876 new coronavirus cases, taking total to 23,336

Singapore registered 876 new coronavirus infections, its health ministry said on Sunday, taking the city-state's total to 23,336 cases.




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France says total death toll from coronavirus rises by 80 to 26,310

The number of people who have died from coronavirus infections in France rose by 80 to 26,310 on Saturday, the health ministry said, a much smaller daily increase than the previous day when it was 243.




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WHO reports over 5,400 new COVID-19 deaths globally as total nears 260,000




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After Ahmedabad and Surat, now total lockdown in Gandhinagar from Sunday




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Gurugram: 11 more containment zones, total 25




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12 more coronavirus cases in India, total 58

In Jaipur, the combination of lopinavir and ritonavir, both second-line HIV drugs, was administered was administered on an elderly Italian couple undergoing treatment for Covid-19 at the SMS Hospital.





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With 2 more Covid deaths, toll hits 9; total cases 468

The Union health ministry said West Bengal and Himachal Pradesh reported a casualty each on Monday, taking the total number of deaths to nine in the country due to COVID-19.




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Covid India toll rises to 16; total cases 694

The Union health ministry officials also said India was at the second stage as there is still no 'hard evidence' to say that there has been community transmission of the fast-spreading coronavirus, remarks which may provide anxious citizens with much needed assurance and hope.





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COVID-19: Toll rises to 169; total cases 5,865

Of the 20 deaths reported in the last 24 hours, eight were from Maharashtra, three each from Gujarat and Madhya Pradesh, two from Jammu and Kashmir and one each from Punjab, Uttar Pradesh, Karnataka and Tamil Nadu.





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JavaScript `foo.prototype.bar` notation

As a follow-up to the post documenting a few popular HTML element + attribute notations, here’s a similar one about JavaScript.




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JavaScript engine fundamentals: optimizing prototypes

This article explains JavaScript engine optimization pipeline trade-offs, and describes how engines such as V8 speed up accesses to prototype properties. As a JavaScript developer, having a deeper understanding of how JavaScript engines work helps you reason about the performance characteristics of your code.




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COVID-19: 13 more test positive, J and K total 836




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Tamil Nadu records 526 new Covid-19 cases, total infections at 6,535

Four deaths reported today including three in Chennai, total fatalities reach 44




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Total lockdown today

Exemption for essential services




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Chandigarh gets 4 more COVID-19 cases, total up to 5




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One more tests positive for COVID-19 in Punjab, total count rises to three




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Three more test positive in Punjab; total rises to six




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One more tests positive for COVID-19 in Punjab, total count mounts 4




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Chandigarh gets 1 more COVID-19 patient, total 6




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Total coronavirus cases touch 29 in Punjab




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Total number of positive COVID-19 cases reach 33 in Punjab




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COVID-19: One more tests positive in Punjab; total cases 39




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Five new coronavirus cases in Chandigarh, total 13




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Total positive COVID-19 cases in Chandigarh rises to 13




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3 more test positive in Punjab; total cases 44




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Ex-Hazoori Raagi of Golden Temple tests positive; total cases 46 in Punjab




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Punjab reports another coronavirus death; total 6




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Seven more COVID-19 cases surface in Punjab, total count 106




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6 new COVID-19 cases in Punjab, total count up to 176




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With 2 new COVID-19 positive cases in Punjab, total count reaches 186




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11 new COVID-19 positive cases in Punjab, state's total count reaches 197




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Punjab's total COVID-19 count rises to 257




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COVID-19: Five more test positive in Chandigarh, total now 50




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8 more test positive in Chandigarh; total cases 67




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In steepest spike, Punjab sees 331 new coron cases; total 1,102





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Now total lockdown in Gandhinagar from Sunday

To curb the increasing number of corona positive cases and the spread of virus infection, the Gandhinagar Collector on Saturday said there would be a total lockdown in Gandhinagar city and Kalol municipality on the lines of Ahmedabad and Surat.




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31 new Covid-19 cases in Punjab, total 1,762




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Calculation of total scattering from a crystalline structural model based on experimental optics parameters

Total scattering measurements enable understanding of the structural disorder in crystalline materials by Fourier transformation of the total structure factor, S(Q), where Q is the magnitude of the scattering vector. In this work, the direct calculation of total scattering from a crystalline structural model is proposed. To calculate the total scattering intensity, a suitable Q-broadening function for the diffraction profile is needed because the intensity and the width depend on the optical parameters of the diffraction apparatus, such as the X-ray energy resolution and divergence, and the intrinsic parameters. X-ray total scattering measurements for CeO2 powder were performed at beamline BL04B2 of the SPring-8 synchrotron radiation facility in Japan for comparison with the calculated S(Q) under various optical conditions. The evaluated Q-broadening function was comparable to the full width at half-maximum of the Bragg peaks in the experimental total scattering pattern. The proposed calculation method correctly accounts for parameters with Q dependence such as the atomic form factor and resolution function, enables estimation of the total scattering factor, and facilitates determination of the reduced pair distribution function for both crystalline and amorphous materials.




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Improving grazing-incidence small-angle X-ray scattering–computed tomography images by total variation minimization

Grazing-incidence small-angle X-ray scattering (GISAXS) coupled with computed tomography (CT) has enabled the visualization of the spatial distribution of nanostructures in thin films. 2D GISAXS images are obtained by scanning along the direction perpendicular to the X-ray beam at each rotation angle. Because the intensities at the q positions contain nanostructural information, the reconstructed CT images individually represent the spatial distributions of this information (e.g. size, shape, surface, characteristic length). These images are reconstructed from the intensities acquired at angular intervals over 180°, but the total measurement time is prolonged. This increase in the radiation dosage can cause damage to the sample. One way to reduce the overall measurement time is to perform a scanning GISAXS measurement along the direction perpendicular to the X-ray beam with a limited interval angle. Using filtered back-projection (FBP), CT images are reconstructed from sinograms with limited interval angles from 3 to 48° (FBP-CT images). However, these images are blurred and have a low image quality. In this study, to optimize the CT image quality, total variation (TV) regularization is introduced to minimize sinogram image noise and artifacts. It is proposed that the TV method can be applied to downsampling of sinograms in order to improve the CT images in comparison with the FBP-CT images.




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Calculation of total scattering from a crystalline structural model based on experimental optics parameters

A calculation procedure for X-ray total scattering and the pair distribution function from a crystalline structural model is presented. It allows one to easily and precisely deal with diffraction-angle-dependent parameters such as the atomic form factor and the resolution of the optics.




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Harvard-Smithsonian Center for Astrophysics to own and operate ALMA Vertex Prototype Antenna

The Harvard-Smithsonian Center for Astrophysics has been selected by the National Science Foundation as the recipient of a 12-meter (39-foot) radio antenna designed for submillimeter-wavelength astronomy. The ALMA Vertex Prototype Antenna was one of three antennas built as prototypes for the Atacama Large Millimeter Array, a 66-dish radio observatory currently being constructed in Chile.

The post Harvard-Smithsonian Center for Astrophysics to own and operate ALMA Vertex Prototype Antenna appeared first on Smithsonian Insider.




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Chondrosarcoma-associated gene 1 (CSAG1) maintains the integrity of the mitotic centrosome in cells with defective p53 [RESEARCH ARTICLE]

Hem Sapkota, Jonathan D. Wren, and Gary J. Gorbsky

Centrosomes focus microtubules to promote mitotic spindle bipolarity, a critical requirement for balanced chromosome segregation. Comprehensive understanding of centrosome function and regulation requires a complete inventory of components. While many centrosome components have been identified, others may yet remain undiscovered. We have used a bioinformatics approach, based on "guilt by association" expression to identify novel mitotic components among the large group of predicted human proteins that have yet to be functionally characterized. Here we identify Chondrosarcoma-Associated Gene 1 (CSAG1) in maintaining centrosome integrity during mitosis. Depletion of CSAG1 disrupts centrosomes and leads to multipolar spindles more effectively in cells with compromised p53 function. Thus, CSAG1 may reflect a class of "mitotic addiction" genes whose expression is more essential in transformed cells.