switch

Nintendo Switch ya está aquí

La nueva consola de Nintendo se pone a la venta el próximo 3 de marzo, pero ya tenemos la máquina con nosotros y os contamos nuestras primeras impresiones con el nuevo hardware.




switch

Former MLA who switched to PCs admits he took Liberal Party information

Former Northside-Westmount Liberal MLA Fred Tilley says he accessed Liberal Party data before he crossed the floor to the PCs, but has not used it in the provincial election campaign.



  • News/Canada/Nova Scotia

switch

This US County Switched To 32-Hour Workweek Last Year. Here Are The Results

San Juan County in Washington has reported an 85.5% spike in job applications, with open positions getting filled 23.75% faster after it shifted to the 32-hour workweek last year.




switch

Woman arrested for killing elderly father with an ice axe after he refused to switch off the lights




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Colts name Anthony Richardson starting quarterback in sudden switch-up: 'We’ve never lost faith'

The Indianapolis Colts are heading in a new direction with the quarterback position again, naming Anthony Richardson the new QB1 just two weeks after he was benched.



  • 25a592ed-0020-5c80-889d-e62fb0cc2e10
  • fnc
  • Fox News
  • fox-news/sports/nfl/indianapolis-colts
  • fox-news/sports/nfl
  • fox-news/sports
  • fox-news/sports
  • article

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Pensioners wary as federal dental plan switches to Canada Life

Sixteen months after Canada Life took over the administration of the Public Service Health Care Plan, hundreds of thousands of federal retirees are hoping to avoid similar problems now that their dental plan is under the same provider.



  • News/Canada/Ottawa

switch

Building Tomorrow's Network: Foundations in Routing and Switching

Ravi Theja Kambhampati's insights highlight the enduring impact of these principles, essential for developing robust, future-ready networks that meet the demands of an increasingly connected world




switch

Chiral guanidine catalyzed cyclization reactions of 1,3-enynes for lactone synthesis: switchable H-bond catalysis

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00374H, Research Article
Yongyan Zhang, Lichao Ning, Tianxin Zhu, Zheng Xie, Shunxi Dong, Xiaoming Feng, Xiaohua Liu
Cyclization and 1,4-conjugate addition/cyclization between 2-activated 1,3-enynes and azlactones were achieved with chiral guanidine-amides for enol-type activation to yield a range of δ-lactone derivatives.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




switch

Electrochemical switching in mechanically interlocked molecules (MIMs)

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00061G, Review Article
Ayush Bhadani, Murugavel Kathiresan
Mechanically interlocked molecules (MIMs) which include rotaxanes and catenanes are formed by the mechanical linking of two or more components and has the ability to switch between different states in the presence of an external stimuli.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




switch

Electrode-switchable: exploring this new strategy to achieve regiodivergent azidoiodination of alkenes

Org. Chem. Front., 2024, 11,2189-2194
DOI: 10.1039/D3QO01935G, Research Article
Xin-Lei Sun, Chen-Xi Xia, Yue Ren, Yu-Jin Li, Zhi-Qian Cao, Ling-Guo Meng
An “electrode-switchable” organic electrochemistry method for the azidoiodination of alkenes, where the choice of anode dictates the regiodivergent alkene azidoiodination, reveals a novel pathway for controlled regioisomers.
The content of this RSS Feed (c) The Royal Society of Chemistry




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An Efficient All-Visible Light-Activated Photoswitches Based on Diarylethenes and CdS Quantum Dots

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC06110A, Edge Article
Open Access
Kezhou Chen, Jiayi Liu, Joakim Andréasson, Bo Albinsson, Tiegen Liu, Lili Hou
All-visible light-activated diarylethene (DAE) photoswitches are highly attractive for applications in smart photoresponsive materials. Photocyclization of DAE via the low-lying excited triplet state through triplet energy transfer (TET) from a...
The content of this RSS Feed (c) The Royal Society of Chemistry




switch

A photoswitchable CENP-E inhibitor with single blue-green light to control chromosome positioning in mitotic cells

RSC Med. Chem., 2024, 15,3795-3799
DOI: 10.1039/D4MD00458B, Research Article
Kazuya Matsuo, Takashi Kikukawa, Tomonori Waku, Akio Kobori, Nobuyuki Tamaoki
A photoswitchable centromere-associated protein E (CENP-E) inhibitor based on the 4-methylaminoazobenzene photoswitch is reported, which is characterized with cistrans photoisomerization with blue-green light and fast thermal relaxation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Good & Bad Reasons to Consider Switching Email Service Providers

Switching email service providers can disrupt your marketing efforts. Assess functionality, data quality and risks to ensure a smooth transition.

Continue reading...




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LEGO Horizon Adventures On Nintendo Switch Runs Pretty Damn Well - Press Start Australia

  1. LEGO Horizon Adventures On Nintendo Switch Runs Pretty Damn Well  Press Start Australia
  2. Lego Horizon Adventures Review  IGN
  3. How LEGO Horizon Adventures was built with real LEGO bricks, out Nov 14  PlayStation
  4. LEGO Horizon Adventures – The Cheapest Australian Day One Bargains  Press Start Australia
  5. Lego Horizon Adventures Review - For Buildin' Jest  GameSpot




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Why the name switch from Snowdonia to Eryri matters

For many Welsh speakers, Eryri and Yr Wyddfa are the names they have used all along.




switch

Loco Motive Releases November 21 for Switch and PC

Publisher Chucklefish and developer Robust Games announced the point-and-click puzzle game, Loco Motive, will launch for the Nintendo Switch and PC via Steam and GOG n November 21 for $17.99 / £14.99 / €17.99.

"Were thrilled to get Loco Motive into the hands of players!” said Robust Games creative director and co-founder Adam Riches. "From the humble origins of a simple game jam to a fully fledged adventure in its own right, the last few years have been a whirlwind."

Robust Games technical director and co-founder Joseph Riches added, "My brother and I always wanted to create something together, and we’re very grateful to have had that opportunity. There was an unrelenting drive to make Loco Motive happen, and it’s our hope that players will see our passion and love for the genre reflected in this game."

View the release date trailer below:

Read details on the game below:

Welcome aboard the Reuss Express, a journey of a life-time derailed by an unexpected assassination.

On the eve of a landmark speech by the wealthy heiress Lady Unterwald, a straight-laced lawyer, a crime novelist-turned rookie detective, and an undercover spy find themselves embroiled in a murder, a mystery, and worst of all… an adventure! Now stuck onboard a luxurious steam train, within stabbing distance of a cold-blooded killer, the race is on to prove their innocence once and for all!

Play as Diana, Arthur and Herman to unwrap the mystery and put your point and click puzzle-solving skills to the test...

Features:

  • A comedy adventure that hits like smooth jazz, set onboard a 1930s express train
  • Take control of three playable characters, in an interlinking comedic adventure
  • Uncover a deadly mystery, full of twists, turns and slapstick humour
  • Meet a train-full of quirky and somewhat suspicious fellow passengers
  • Stop at nothing to solve item-based puzzles, that won’t leave you head-scratching for hours
  • Choose how you play - take direct interactive character control, or opt for a classic point and click experience
  • Beautifully detailed pixel art animations
  • Need a little nudge in the right direction? Telephone for assistance with an in-game hint call-line!
  • With the slinky sounds of composer Paul Zimmermann (Wildfrost, Space Haven)
  • Voice Acting!

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012 and taking over the hardware estimates in 2017. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel. You can contact the author on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/463050/loco-motive-releases-november-21-for-switch-and-pc/




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HEAVEN SEEKER: The Savior of This Cruel World Releases December 5 for PS5, PS4, and Switch

SUCCESS Corporation announced the twin-stick roguelite shooter, HEAVEN SEEKER: The Savior of This Cruel World, will launch for the PlayStation 5, PlayStation 4, and Nintendo Switch on December 5.

Read details on the game below:

HEAVEN SEEKER: The Savior of This Cruel World is a twin-stick roguelite shooter where you take your own shot at the castle in the sky! A dungeon with a different structure each time you enter, a variety of magic bullets—and a formidable barrage of bullets—await you.

Story

In this world, Pentagaia, there were five countries that had been transferred from five different worlds.

Magi Province, the land of wizards, where magical technology flourished. A land of priestesses and samurai, a land of warriors and the four seasons. A land of elves, with the blessings of the World Tree. A land of mechanical ingenuity, where super-science rules the world. A land of wilderness and dust, ruled by demons.

The rulers of each nation sent explorers to the Castle of Heaven, where the secrets of Pentagaia were said to lie. They did so with the longing to return to the original world. These explorers were called Heaven Seekers.

Explore a Dungeon That Changes Each Time You Enter

In this title, you move with the left stick and aim with the right stick. This is a bullet hell shooting game where you freely control your character and explore random dungeons. When your HP reaches 0, you will lose all the items you have gained during this exploration. The player gains experience by exploring many times and learning the patterns of the rooms and the nature of the enemies.

Create Your Own Magic Shot!

The shot fired by the player character can be modified by freely combining over 20 customizable items to change its properties. Since items are randomly acquired during each quest, players will fight with a different personalized shot each time they dive into a dungeon.

Dot Art Style Game Visuals

All in-game elements in this title, including player characters, enemies, and dungeons, are rendered in high-quality dot art.

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012 and taking over the hardware estimates in 2017. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel. You can contact the author on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/463057/heaven-seeker-the-savior-of-this-cruel-world-releases-december-5-for-ps5-ps4-and-switch/




switch

Correlation between organic residuals of green synthesized nanoparticles and resistive switching behavior

RSC Adv., 2024, 14,36340-36350
DOI: 10.1039/D4RA04381B, Paper
Open Access
Trung Bao Ngoc Duong, Phu-Quan Pham, Anh Thuy Tran, Dat Tan Bui, Anh Tuan Thanh Pham, Tien Cam Thi Nguyen, Linh Ho Thuy Nguyen, Thuy Dieu Thi Ung, Nam Vu Hoang, Ngoc Kim Pham
The analog characteristics and RS mechanism of ZnO-based memristors.
The content of this RSS Feed (c) The Royal Society of Chemistry




switch

Bush Bait and Switch

IT'S A VARIATION OF the tried and proven bait and switch technique. You screw up, so what do you do? After denial and the passage of time no longer works, first you 'sincerely' apologize.

Then you provide a new and grandiose vision for the future that the people can focus on, and soon (hopefully) all of your past sins will be forgotten. He said what needed to be said, or should I say what the public wanted to hear. It's a strategy that Karl Rove can be proud:

"The main text of President Bush's nationally televised address last night was the rebuilding of New Orleans and the Gulf Coast, but the clear subtext was the rebuilding of a presidency that is now at its lowest point ever, confronted by huge and simultaneous challenges at home and abroad -- and facing a country divided along partisan and racial lines.

Hurricane Katrina struck at the core of Bush's presidency by undermining the central assertion of his reelection campaign, that he was a strong and decisive leader who could keep the country safe in a crisis. Never again will the White House be able to point to his often-praised performance after the attacks of Sept. 11, 2001, without skeptics recalling the fumbling and slow-off-the-mark response of his administration after the hurricane and the flooding in New Orleans.

His response to these criticisms last night was a speech largely shorn of soaring rhetoric and stirring turns of phrase of the kind that marked his efforts to rally the country after the terrorist attacks. Instead, as if recognizing that his own road back will be one marked by steady but small steps, he spoke with workmanlike focus, spelling out the details of what has been done and will be done to help those displaced by the storm.

In again taking responsibility for the federal government's failures, Bush signaled last night that the White House has decided not to contest the widespread perceptions that his administration failed in the early days of the crisis. By embracing those criticisms, they hope to make the issue a sideshow that will play out sometime in the future. Instead, after a halting start, the White House appears intently focused on demonstrating the president's capacity to manage the huge rebuilding effort ahead.

Bush's advisers believe that, despite the partisan finger-pointing over what happened, most Americans are not looking back and will judge the president on what happens going forward. But as Iraq has shown over the past two years, the facts on the ground shape public confidence in the president more than words or promises."

THE QUESTION REMAINS, will it be enough to repair the presidency and his ability to govern effectively for the remaining 40 months?

TALK IS CHEAP. For a fiscally conservative government, will they, or can they possibly deliver?




switch

Smiley Face Light Switch Cover

Share the warmth and happiness of a friendly smile with all those around you with this Smiley Face Light Switch Cover - It's back! The ever popular, the ever lovable, the ever friendly the totally universal smiley face is back once again. Only this time it's in the new and improved wonderful and modern 3d design. Maybe your face isn't always shining with a smile, even if you are smiling inside, but this design will help you share your internal or external smile. People around you and those that see you will more than likely grin and smile back at you as they see the smile that you are sporting on your shirt, coffee cup or other 3d smiley face designed accessory. Share the warmth and happiness of a friendly smile with all those around you directly and indirectly.




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Nintendo Switch 2 : les jeux Switch seront tous rétro-compatibles, Nintendo a pris la parole dans la nuit

Ça été officialisé cette nuit par Mr Shuntaro Furukawa, l'actuel big boss de Nintendo, la Nintendo Switch 2 (nom de code temporaire) sera rétrocompatible avec tous les jeux de...




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Apple to switch its 'Subscribe' button to 'Follow' on Podcasts

Apple to switch its 'Subscribe' button to 'Follow' on Podcasts




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Uswitch

Uswitch Energy Comparison




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Nigeria: Why Everyone Is Talking About DJ Switch's 'Link Up' Video

[Premium Times] After a period of silence, DJ Switch has made a striking comeback with her new single, 'Link Up', sparking significant conversation.




switch

Arcep consults on new guidelines for fibre operators to support copper network switch-off

(Telecompaper) France's telecom authority Arcep has published draft recommendations for public consultation with the aim to clarify what operators should do in...




switch

FS: White RTX 3060 Ti, 3070, 3080 BNIB and used. White OLED Switch



  • For Sale / Trade

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The 20+ best Black Friday Nintendo Switch deals 2024: Early sales live now

The holidays are just around the corner, which means it's a great time to snag deals on Nintendo Switch consoles, games, and accessories for everyone on your shopping list.




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Christmas lights switch-ons across the North West

Lantern parades, fire festivals and light trails mark the start of the festive season in the region.




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Trafalgar Square Christmas Tree 2024: Where's It From? What's Its History? When Is The Switch-On?

Spruce up on your arboreal knowhow.





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Is Nintendo Switch 2 about to be announced? Instagram lowers quality of less popular videos

The internet is still convinced a Nintendo Switch 2 announcement is going to happen this month, as a part of a major third-party open world game is also rumoured. It’ll […]

The post Is Nintendo Switch 2 about to be announced? Instagram lowers quality of less popular videos appeared first on ShinyShiny.




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Alpine confirm switch to Mercedes power when Renault ends F1 engine project | Formula 1

Alpine have officially announced they will use Mercedes power units when Formula 1 introduces its new engine regulations in 2026.




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BSP finalizing framework for clearing switch operations

The Bangko Sentral ng Pilipinas is finalizing a regulatory framework to ensure the efficiency of clearing switch operations within the national payment system, particularly the automated clearing houses under the National Retail Payment System.




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Wave of job-switching has employers on a training treadmill

“A lot of restaurants are in survival mode, and survival mode creates a vicious circle,” said Dominic Benvenuti, an owner of Boston Pie, which owns more than two dozen Domino’s locations in New England.

The post Wave of job-switching has employers on a training treadmill appeared first on Boston.com.




switch

Werner Announces New Bantam Switch, First Reverse-System Self-Retracting Lifeline

Werner introduced on Feb. 5 the new Bantam Switch, the first reverse-system self-retracting lifeline, for pros working at height. The SRL transfers weight of the housing unit from the user’s back to the anchor point and lightens the load to 0 pounds.




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How POE+ Switch Can Make Outdoor Cameras Easy & Quick to Install

One of the realities of living in rural Michigan is that AC power outages happen — and you best be prepared for the potential consequences. 




switch

OSHA staff switch to safety helmets from hard hats

Washington — OSHA personnel will now wear safety helmets instead of traditional hard hats to “protect them better when they are on inspection sites.”




switch

Machine interlock switch

The Proton is an advanced solenoid interlock switch designed for use on machines for which hazardous conditions persist even after the machine has been switched off. Its heavy-duty solenoid can withstand up to 3000N hold force and energize under a lateral load.




switch

Understanding the Increased Demand for Industrial Switches in Food and Beverage Plants

What qualities to look for in an industrial Ethernet switch that can provide long-term reliability in an F&B plant.




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Clinical, Quality of Life, and Health Care Utilization Outcomes of Switching the Administration Route of Antipsychotic Medications Among People With Schizophrenia Spectrum Disorder: A Systematic Review and Meta-Analysis

Journal of the American Psychiatric Nurses Association, Ahead of Print. Background:Using long-acting injectable (LAI) antipsychotic medications can improve the outcomes of patients with schizophrenia, such as reducing symptom severity and hospitalization risk. However, the outcomes of switching from oral to LAI antipsychotic medications are unclear.Aims:The purpose of this review is to provide a summary of […]

The post Clinical, Quality of Life, and Health Care Utilization Outcomes of Switching the Administration Route of Antipsychotic Medications Among People With Schizophrenia Spectrum Disorder: A Systematic Review and Meta-Analysis was curated by information for practice.



  • Meta-analyses - Systematic Reviews

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Russia wonders how the West may to switch to green energy if it needs black coal

The upcoming UN conference on climate change in Glasgow was supposed to show the world the triumph of the United States and the European Union as trendsetters for everything "green". Unfortunately for them, Europe faced an unprecedented energy crisis, which called into question not only the competence of officials from Brussels, but also the feasibility of the strategy to switch to green energy as soon as possible. Russia, which did not want to dive into the whirlpool of decarbonization, found itself in a more advantageous position. Nevertheless, Moscow has something to show in Glasgow on the climate agenda. China, the United States and India altogether account for more CO2 emissions than all other countries combined. Russia accounts for less than five percent, but the anger of Western politicians and journalists, who propagate environmental slogans, is directed primarily at Russia. Such a biased attitude towards Russia is based on the laws of hybrid war: dirty propaganda should keep citizens in good shape, while raising the degree of hatred. EU demonises Russia and wants more Russian gas When European politicians accuse Russia of the gas crisis, their accusations fit into the anti-Russian agenda just as perfectly. Gazprom strictly fulfills all of its contracts, but this argumentation falls on deaf ears in the EU. For example, EU chief diplomat Josep Borrell saw "deep geopolitical roots" in the rise in energy prices. The head of the European Commission, Ursula von der Leyen, reproached the Russian gas monopoly for "not responding to higher demand" in Europe. Her compatriot from the Green party, claiming the portfolio of the Minister of Foreign Affairs of the Federal Republic of Germany, Annalena Baerbock, stated that Russia was "playing poker" in matters of gas supplies. She has an ironclad argument: after all, European gas storage facilities are comparatively empty.




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Uswitch broadband experts unveil the reality of online security habits

In recognition of Cyber Security Awareness Month, Uswitch Broadband experts set out to explore how well people are protecting themselves online. The survey uncovered common mistakes that leave people vulnerable to cyber risks, along with actionable tips on how to safeguard personal information.




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Plug & Print coding & marking system – just switch it on and start printing

Leibinger introduced what it describes as the world’s first intelligent coding & marking system – the IQJET – on May 3 in Düsseldorf, the day before the opening of the interpack trade show.



  • Print and Label

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USA gradually switches Ukraine to terrorist war against Russia

US Congress will provide $61 billion in military aid to Ukraine. Will Joseph Biden decide to transfer long-range missiles to Kyiv? Does Washington prepare for a terrorist war against Russia? Pravda.Ru asked these and other questions to Alexander Dudchak, candidate of economic sciences, leading researcher at the Institute of CIS Countries. The US Congress approved $61 billion in aid to Ukraine, but this money will be distributed between Ukraine, the American military-industrial complex and allies in Europe for arms procurement. What do you think of the bill? The decision did not come as a surprise. Of course, the bulk of the amount will be spent to support the US defence industry. The Americans say that they need long-term contracts to support the defence industry, and Washington is getting them by supporting Kyiv and the hostilities in Ukraine. A lion's share of those billions will be spent to support the US defence industry in the first place. In addition, they will allocate money for the National Nuclear Safety Committee and the Ministry of Health.




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Structural analysis of a ligand-triggered intermolecular disulfide switch in a major latex protein from opium poppy

Several proteins from plant pathogenesis-related family 10 (PR10) are highly abundant in the latex of opium poppy and have recently been shown to play diverse and important roles in the biosynthesis of benzylisoquinoline alkaloids (BIAs). The recent determination of the first crystal structures of PR10-10 showed how large conformational changes in a surface loop and adjacent β-strand are coupled to the binding of BIA compounds to the central hydrophobic binding pocket. A more detailed analysis of these conformational changes is now reported to further clarify how ligand binding is coupled to the formation and cleavage of an intermolecular disulfide bond that is only sterically allowed when the BIA binding pocket is empty. To decouple ligand binding from disulfide-bond formation, each of the two highly conserved cysteine residues (Cys59 and Cys155) in PR10-10 was replaced with serine using site-directed mutagenesis. Crystal structures of the Cys59Ser mutant were determined in the presence of papaverine and in the absence of exogenous BIA compounds. A crystal structure of the Cys155Ser mutant was also determined in the absence of exogenous BIA compounds. All three of these crystal structures reveal conformations similar to that of wild-type PR10-10 with bound BIA compounds. In the absence of exogenous BIA compounds, the Cys59Ser and Cys155Ser mutants appear to bind an unidentified ligand or mixture of ligands that was presumably introduced during expression of the proteins in Escherichia coli. The analysis of conformational changes triggered by the binding of BIA compounds suggests a molecular mechanism coupling ligand binding to the disruption of an intermolecular disulfide bond. This mechanism may be involved in the regulation of biosynthetic reactions in plants and possibly other organisms.




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HANTEMP Controls adjustable float level switch

HANTEMP Controls Stainless Steel Float-Switch line has expanded to include the new SSLLA adjustable Float Switch.




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John Siegenthaler: Relays and switches — part one

The basics of relays and switches - part one.




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Relays and switches — part two

Last month, we covered the basics of classifying switches and relays based on poles and throws. Once you learn these, it’s easy to apply switches and relays to create “hard-wired” control logic - part two.




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Switching heat pumps between domestic water heating and cooling

Air-to-water heat pumps and water-to-water geothermal heat pumps provide warm water for space heating, domestic water heating, and chilled water for cooling. Switching a hydronic heat pump system from space heating to cooling and vice versa seasonally is relatively simple. The system operating mode is changed at the thermostat or a dedicated system mode switch with heat, off, and cool settings.