signals PTA signals further VPN curbs By www.dawn.com Published On :: Thu, 14 Nov 2024 11:22:14 +0500 ISLAMABAD: Following a disruption that rendered virtual private networks (VPNs) dysfunctional across the country, the Pakistan Telecommunication Authority (PTA) on Wednesday said that VPN usage would be restricted in the future to curb access to pornographic content. In a statement, the authority claimed it had so far blocked 100,183 URLs containing blasphemous content, as well as 844,008 pornographic websites. The statement by PTA highlighting its performance came a day after the Ministry of Religious Affairs and Interfaith Harmony wrote to the regulator to ask it to block blasphemous and pornographic content. “In addition to PTA’s proactive efforts, individuals and government organisations also report such sites,” the statement added. The telecom regulator also claimed that approximately 20 million attempts were made from within the country to access pornographic websites on a daily basis, which were blocked at the international gateway level. “However, users bypass restrictions via VPNs and access porn contents, PTA remains fully committed to curbing this issue, taking all necessary measures to block this content effectively,” the statement added. In another statement, the telecom regulator said it had organised a consultation on the issue of VPN use, attended by representatives from the Ministry of IT & Telecommunication (MoIT&T), the Pakistan Software Export Board (PSEB), and the Pakistan Software Houses Association (P@SHA). “The PTA introduced a streamlined VPN registration process, allowing legitimate users to register their VPNs through a new online portal at ipregistration.pta.gov.pk,” the statement said. However, a senior executive from an internet service provider — in response to a Dawn query — said the authority was “making excuses”. “How would they know that people are watching porn through VPNs? They have no capability to [monitor traffic through] VPNs, otherwise they would not block it,” the executive said. He said the main target was blocking access to X and other social media platforms. Published in Dawn, November 14th, 2024 Full Article Tech
signals Steve Brenner - Signals (1985) [full album] By lj.rossia.org Published On :: Thu, 31 Oct 2024 18:31:13 GMT А вот это неиллюзорно шедеврhttps://www.youtube.com/watch?v=pP4Cct_1di8Steve Brenner - Signals (1985) [full album]https://stevebrenner.bandcamp.com/album/s-i-g-n-a-l-sТипа имитация Tangerine Dream синхронного периода,но сильно лучше, чем все, что они сделали после 1984,причем записано (в домашней студии, насколько я понимаю)на порядок чище и яснее, чем TD писали, со всеми их сотнямитысяч долларов, вбуханных в аппаратуру.Я долго тыкался в биографию автора, пытаясь выяснить,1985 это не мистификация ли, так и не понял. В принципе,что сейчас подобной ретрофутуристической музыки пишуточень много, с реверансами в сторону 1970-х и 1980-х,лепят на альбом фальшивую датировку, и выкладывают на ютюб,зарабатывая миллионы прослушиваний.Вообще Ютюб разрушил централизованную систему музыкальнойкритики и прессы, раньше люди шли читать про группы вПитчфорк или Wire, и покупали альбом, а сейчас тыкаютв рекоммендации Ютюба. Это породило с десяток новых жанров,свободных от кураторства музкритика, с изобретенной(и часто целиком фальсифицированной) историей. Походупоявилась масса "групп", датированных на 30-40 летраньше, чем на самом деле, и зачастую сгенерированныхчерез AI, с имитацией всякого ретро; наиболее смешнойобразчик вот, с ним-то все яснее ясногоhttps://bannedvinyl.bandcamp.com/https://www.youtube.com/watch?v=VcDeZWIF1kYhttps://www.youtube.com/@bannedvinylно вообще имитаций-мистификаций на ютюбе появилосьочень много, спасибо AI, и в основном оно весьма трудно распознается.В любом случае, "Signals" Бреннера, безотносительнок его аутентичности, совершенно прекрасен; особенноесли вы послушали весь доступный Танжерин Дрим ижелаете еще.Привет Comments Full Article music prog td youtube
signals THE ONLINE SHADOW OF OFFLINE SIGNALS: WHICH SELLERS GET CONTACTED IN ONLINE B2B MARKETPLACES? By amj.aom.org Published On :: Wed, 22 Jul 2015 14:48:34 +0000 This article extends the understanding of what impels buyers to contact particular sellers in online business-to-business (B2B) marketplaces, which are typically characterized by sparse social structures and concomitant limitations in observing social cues. Integrating an institutional perspective with signaling theory, our core argument is that offline seller characteristics that are visible online—in particular, geographic location and legal status—convey credible signals of seller behavior because they provide buyers with information on sellers' local institutional quality and the institutionally-induced obligations and controls acting on sellers. Using unique data from a large Italian online B2B marketplace between the fourth quarter of 1999 and July 2001, we find that both sellers' local institutional quality and their legal statuses affect a buyer's likelihood of contacting a seller. Moreover, consistent with the idea that a buyer's own local institutional quality generates a relevant reference point against which sellers are evaluated, we find that a buyer is progressively more likely to contact sellers the higher their local institutional quality relative to the buyer. Jointly, our findings imply that in online B2B marketplaces, signals conveyed by sellers' geographic locations and legal statuses may be substantive sources of competitive heterogeneity and market segmentation. Full Article
signals Judge In Absolute Bullshit Copyright Case Against Mariah Carey Signals She’s Leaning Carey’s Way By www.techdirt.com Published On :: Wed, 13 Nov 2024 03:54:58 +0000 As the saying goes, the arc of morale judgment is long, but it does bend towards justice. And even if we accept such an optimistic worldview is relevant in this year of our lord, 2024, that certainly doesn’t mean we can’t bitch about how long that damned arc is. It’s been over two years since […] Full Article 1 all i want for christmas is you andy stone christmas songs copyright mariah carey vince vance
signals Signs and signals By www.bbc.co.uk Published On :: Sat, 04 May 2019 01:30:00 +0000 Seattle, Washington, is widely seen as a pro-immigrant city. So many residents were shocked to learn that a nearby airport has been used to deport some 34,000 people in the last eight years. Now King County, where the airport is located, is signalling its opposition to those deportations. We also learn about a subversive hand sign adopted from Hollywood and used in Thailand; we visit a radio program whose signals connect families split between central California and southern Mexico; we meet a teacher who’s helping kids feel proud to communicate in their native tongues; we hear from a man who learned how to deal with a misreading of his name; and we hear the music of a man who won’t yield to pressure to spell it all out.(Detainees are loaded onto a Swift Air charter flight at King County International Airport (Boeing Field) in Seattle, WA, for a February 26 ICE Air flight. Credit: Still image from video by Alex Montalvo and Wadii Boughdir for the University of Washington Center for Human Rights) Full Article
signals 2013 Laminate Market Study: Mixed Signals for Sturdy Segment By www.floortrendsmag.com Published On :: Thu, 08 Aug 2013 00:00:00 -0400 Laminate flooring is a segment growing in usage and profitability in some areas, but losing ground in others. Full Article
signals N. Korea Jams GPS Signals for Fifth Straight Day By world.kbs.co.kr Published On :: Tue, 12 Nov 2024 15:12:46 +0900 [Politics] : The South Korean military announced Tuesday that North Korea has attempted to disrupt GPS signals in the western inter-Korean border region for the fifth straight day. During a regular press briefing, Joint Chiefs of Staff(JCS) spokesperson Lee Sung-jun said the latest GPS-jamming attempts occurred ...[more...] Full Article Politics
signals Utilizing anomalous signals for element identification in macromolecular crystallography By journals.iucr.org Published On :: 2024-09-18 AlphaFold2 has revolutionized structural biology by offering unparalleled accuracy in predicting protein structures. Traditional methods for determining protein structures, such as X-ray crystallography and cryo-electron microscopy, are often time-consuming and resource-intensive. AlphaFold2 provides models that are valuable for molecular replacement, aiding in model building and docking into electron density or potential maps. However, despite its capabilities, models from AlphaFold2 do not consistently match the accuracy of experimentally determined structures, need to be validated experimentally and currently miss some crucial information, such as post-translational modifications, ligands and bound ions. In this paper, the advantages are explored of collecting X-ray anomalous data to identify chemical elements, such as metal ions, which are key to understanding certain structures and functions of proteins. This is achieved through methods such as calculating anomalous difference Fourier maps or refining the imaginary component of the anomalous scattering factor f''. Anomalous data can serve as a valuable complement to the information provided by AlphaFold2 models and this is particularly significant in elucidating the roles of metal ions. Full Article text
signals NIST and Navy tests suggest telecom networks could back up GPS time signals By esciencenews.com Published On :: Fri, 09 Sep 2016 19:38:03 +0000 Precision time signals sent through the Global Positioning System (GPS) synchronize cellphone calls, time-stamp financial transactions, and support safe travel by aircraft, ship, train and car. read more Full Article Earth & Climate
signals "Investment Goldmine": South Carolina's CON Repeal Signals Healthcare Industry Shift By www.24-7pressrelease.com Published On :: Wed, 22 May 2024 08:00:00 GMT Independent Medical Facilities Are Positioned as the New Wealth Vehicles for Investors Full Article
signals Kalibri Labs Unveils OTB Signals By www.24-7pressrelease.com Published On :: Fri, 11 Oct 2024 08:00:00 GMT Signals: A Game-Changing Innovation for the Hospitality Industry Full Article
signals Dead Cells Release Wound-Healing Signals By www.labroots.com Published On :: Thu, 12 Sep 2024 06:30:00 -0700 Inflammation is the body’s natural response to injury and infections. It promotes healing through immune cell activation to target bacteria and Full Article Cell & Molecular Biology
signals SETI Institute and Partners Pioneer Search for Extraterrestrial Signals Beyond the Milky Way By www.labroots.com Published On :: Wed, 28 Aug 2024 16:10:00 -0700 Are we alone in the universe, and could we find intelligent life beyond the confines of our Milky Way Galaxy? This is what a first-of-its-kind study conduc Full Article Space & Astronomy
signals SETI Institute and Partners Pioneer Search for Extraterrestrial Signals Beyond the Milky Way By www.labroots.com Published On :: Wed, 28 Aug 2024 16:10:00 -0700 Are we alone in the universe, and could we find intelligent life beyond the confines of our Milky Way Galaxy? This is what a first-of-its-kind study conduc Full Article Earth & The Environment
signals Dead Cells Release Wound-Healing Signals By www.labroots.com Published On :: Thu, 12 Sep 2024 06:30:00 -0700 Inflammation is the body’s natural response to injury and infections. It promotes healing through immune cell activation to target bacteria and Full Article Immunology
signals SpaceX’s Bid to Upend NLRB Follows Signals From Supreme Court By www.littler.com Published On :: Tue, 16 Jan 2024 22:28:42 +0000 Alexander MacDonald comments on the implications of SpaceX’s lawsuit against the NLRB, which alleges that the board violates constitutional separation of powers and due process protections by wielding different types of authority in the same case. Bloomberg Law View (Subscription required.) Full Article
signals OSC Investor Alert: FX Bit Pro and BitFxProSignals By www.osc.ca Published On :: Fri, 28 May 2021 13:19:58 GMT TORONTO – The Ontario Securities Commission (OSC) is warning Ontario investors that FX Bit Pro and BitFxProSignals are not registered to deal or advise in securities in Ontario. Full Article
signals Field devices and signals used for LV SCADA operations By electrical-engineering-portal.com Published On :: Thu, 05 Sep 2019 14:47:04 +0000 At low voltage level, SCADA applications are usually used for process control and monitoring of equipment. Furthermore, incoming circuit breakers or switch disconnectors inside large LV switchboards may also be operated remotely, by the command given from the SCADA working... Read more The post Field devices and signals used for LV SCADA operations appeared first on EEP - Electrical Engineering Portal. Full Article Metering Monitoring Premium Content SCADA electromagnetic flow field devices hmi plc protection relay regulation valves scada scada operations transformer protection variable frequency drive
signals Biden will NOT attend UN climate summit in Azerbaijan: Media reacts: ‘US absence at COP29 signals retreat from climate action, jeopardizing global emission-cutting goals’ – ‘Particularly concerning’ By www.climatedepot.com Published On :: Mon, 11 Nov 2024 14:55:20 +0000 https://tribune.com.pk/story/2508719/shifting-climate-priorities After years of urgent calls for climate action, global leaders from key economies are now opting out of the United Nations COP29 summit in Baku, Azerbaijan – a troubling signal for international climate efforts. The absence of the US in the summit starting today is particularly concerning. President Joe Biden will not attend, citing […] Full Article Special Reports biden cop29 Harris trump
signals [ P.501 (03/17) ] - Test signals for use in telephonometry By www.itu.int Published On :: Wed, 27 Nov 2019 16:09:00 GMT Test signals for use in telephonometry Full Article
signals [ N.63 (11/88) ] - Test signals to be used by the broadcasting organizations during the preparatory period By www.itu.int Published On :: Wed, 30 May 1990 00:00:00 GMT Test signals to be used by the broadcasting organizations during the preparatory period Full Article
signals [ N.60 (03/93) ] - Nominal amplitude of video signals at video interconnection points By www.itu.int Published On :: Mon, 14 Mar 1994 00:00:00 GMT Nominal amplitude of video signals at video interconnection points Full Article
signals [ N.60 (11/88) ] - Nominal amplitude of video signals at video interconnection points By www.itu.int Published On :: Mon, 10 Mar 2008 08:51:00 GMT Nominal amplitude of video signals at video interconnection points Full Article
signals [ Z.161.1 (10/22) ] - Testing and Test Control Notation version 3: TTCN-3 language extensions: Support of interfaces with continuous signals By www.itu.int Published On :: Wed, 30 Nov 2022 10:09:00 GMT Testing and Test Control Notation version 3: TTCN-3 language extensions: Support of interfaces with continuous signals Full Article
signals [ X.1094 (03/19) ] - Telebiometric authentication using biosignals By www.itu.int Published On :: Tue, 25 Jun 2019 11:32:00 GMT Telebiometric authentication using biosignals Full Article
signals From Thoughts To Words: How AI Deciphers Neural Signals To Help A Man With ALS speak By www.discovermagazine.com Published On :: Sat, 31 Aug 2024 14:00:00 GMT "Brain-computer interfaces are a groundbreaking technology that can help paralyzed people regain functions they’ve lost." Full Article Technology
signals Genetic Signals Linked to X Chromosome Loss Later in Life By www.the-scientist.com Published On :: Tue, 12 Nov 2024 05:00:32 GMT Loss of the X chromosome increases with age and may have implications for health and disease risk. Full Article News News & Opinion
signals Six Insights on Preference Signals for AI Training By creativecommons.org Published On :: Fri, 23 Aug 2024 14:49:02 +0000 “Eagle Traffic Signals – 1970s” by RS 1990 is licensed via CC BY-NC-SA 2.0.. At the intersection of rapid advancements in generative AI and our ongoing strategy refresh, we’ve been deeply engaged in researching, analyzing, and fostering conversations about AI and value alignment. Our goal is to ensure that our legal and technical infrastructure remains… The post Six Insights on Preference Signals for AI Training appeared first on Creative Commons. Full Article Events Licenses & Tools Policy Technology AI AI & the Commons AI in Public Interest
signals How Does Google+ Social Signals Effect Websites and Posting’s? By linkworxseo.wordpress.com Published On :: Wed, 12 Mar 2014 19:09:11 +0000 Okay, recently there has been some discussion surrounding the Google Authorship and Publisher topic. So I figured what a great time to cover another article for the topic since it has been part of an update being done for some websites I am working on. First off, there has been some more talk about the […] Full Article SOCIAL MEDIA MARKETING (SMO) google organic-ranking search-results social-signals
signals The break-up of Scholz’s coalition government signals the end of Germany’s old economic model By www.chathamhouse.org Published On :: Tue, 12 Nov 2024 15:12:46 +0000 The break-up of Scholz’s coalition government signals the end of Germany’s old economic model Expert comment jon.wallace 12 November 2024 The coalition could not agree how to fund new support for Ukraine and failed to fully implement the ‘Zeitenwende’. A new government must push through reform. As Europeans were still processing Donald Trump’s victory in the 2024 US presidential election, an acrimonious break up occurred 4000 miles east of Washington DC.Reports had been circulating for weeks about the fragile state of Germany’s ‘traffic light’ coalition government led by German Chancellor Olaf Scholz, consisting of the centre-left Social Democratic Party (SPD), the Green Party, and liberal Free Democratic Party (FDP).The expectation had been that the coalition would hold on for a few more weeks and might even be given a new lease of life by Trump’s re-election. Instead, it collapsed on the day Trump’s win was confirmed. An unusually angry Scholtz announced in a live address that he had fired FDP Finance Minister Christian Lindner, effectively breaking up the coalition. Related content Independent Thinking: Can Germany lead in a divided Europe? At the heart of the dispute was the so-called ‘debt brake’ – a constitutional mechanism which restricts Germany’s annual public deficit to 0.35 per cent of GDP. Lindner proposed a set of reforms which were unpalatable to the SPD and the Greens. In response, Scholz suggested declaring an emergency, which would have suspended the debt brake. That in turn was unacceptable to Lindner, leading to his sacking by the Chancellor.Practically, this means the SPD and the Greens are now in a minority coalition, without agreement on the 2025 budget or the votes in parliament to pass it. They also still face the challenge of the debt brake.A vote of confidence will take place in December, with elections to be held before the end of February 2025 latest.The end of Germany’s economic modelAt the root of Germany’s political crisis is the country’s economic model. For decades, Germany relied on a system that depended on cheap Russian gas, cheap imports of consumer goods from China, high-value exports – particularly in the automotive sector – and the US security umbrella.With Russian energy no longer viable, the global economic landscape shifting, and Donald Trump on his way back to the White House, that model is no longer workable. And Germany’s economy is expected to contract by 0.2 per cent in 2024 – a contraction for the second year running. Germany has struggled to turn around its economic woes, with the car industry particularly affected. The ‘Zeitenwende’, announced by Scholz in the wake of Russia’s full-scale invasion of Ukraine, should have signalled a turnaround of both foreign and economic policy, given how much the two are interconnected. Yet on both fronts, too little changed.Germany’s reliance on Russian gas did come to an abrupt end in 2022. And Germany is Ukraine’s second largest military aid donor after the US, while accepting the most Ukrainian refugees.But the ‘Zeitenwende’ turnaround ended there. Scholz’s coalition government failed to prepare for long-term investment in defence at the levels required by creating an off-budget defence spending fund which would have run out in 2027. The draft budget for 2025 showed defence spending would have been cut, as would support for Ukraine.Germany has also struggled to turn around its economic woes, with the car industry particularly affected. Cheap Chinese EVs and new energy technologies are competing with Germany’s most powerful companies. Volkswagen, the country’s largest car manufacturer, has announced plant closures and layoffs due to shrinking profit margins. To the west, Trump’s threat to impose 10 to 20 per cent tariffs on all EU imports meant share prices of Volkswagen, BMW, Mercedez-Benz and Porsche all dropped between 4 to 7 per cent following news of his re-election.To the east, trade tensions between the EU and China are intensifying. Yet rather than choosing to diversify, German companies have doubled down on their bets in China, with German investment in the country rising from €6.5bn for the whole of 2023 to €7.3bn in the first half of 2024 alone – only exposing carmakers further.Germany’s support for UkraineLike French President Emmanuel Macron, Scholz had already been weakened by the results of the European Parliamentary elections in June. With the collapse of his traffic light coalition, the EU’s Franco-German ‘engine’ is now well and truly stalled – until new leadership can be found. This weakness comes at a perilous moment when clear, united European leadership, and much increased funding, is needed to shore up support for Ukraine. Full Article
signals The Neuroproteomic Basis of Enhanced Perception and Processing of Brood Signals That Trigger Increased Reproductive Investment in Honeybee (Apis mellifera) Workers [Research] By www.mcponline.org Published On :: 2020-10-01T00:05:25-07:00 The neuronal basis of complex social behavior is still poorly understood. In honeybees, reproductive investment decisions are made at the colony-level. Queens develop from female-destined larvae that receive alloparental care from nurse bees in the form of ad-libitum royal jelly (RJ) secretions. Typically, the number of raised new queens is limited but genetic breeding of "royal jelly bees" (RJBs) for enhanced RJ production over decades has led to a dramatic increase of reproductive investment in queens. Here, we compare RJBs to unselected Italian bees (ITBs) to investigate how their cognitive processing of larval signals in the mushroom bodies (MBs) and antennal lobes (ALs) may contribute to their behavioral differences. A cross-fostering experiment confirms that the RJB syndrome is mainly due to a shift in nurse bee alloparental care behavior. Using olfactory conditioning of the proboscis extension reflex, we show that the RJB nurses spontaneously respond more often to larval odors compared with ITB nurses but their subsequent learning occurs at similar rates. These phenotypic findings are corroborated by our demonstration that the proteome of the brain, particularly of the ALs differs between RJBs and ITBs. Notably, in the ALs of RJB newly emerged bees and nurses compared with ITBs, processes of energy and nutrient metabolism, signal transduction are up-regulated, priming the ALs for receiving and processing the brood signals from the antennae. Moreover, highly abundant major royal jelly proteins and hexamerins in RJBs compared with ITBs during early life when the nervous system still develops suggest crucial new neurobiological roles for these well-characterized proteins. Altogether, our findings reveal that RJBs have evolved a strong olfactory response to larvae, enabled by numerous neurophysiological adaptations that increase the nurse bees' alloparental care behavior. Full Article
signals Striatal Serotonin Release Signals Reward Value By www.jneurosci.org Published On :: 2024-10-09 Mitchell G. SpringOct 9, 2024; 44:e0602242024-e0602242024BehavioralSystemsCognitive Full Article
signals Striatal Serotonin Release Signals Reward Value By www.jneurosci.org Published On :: 2024-10-09T09:30:20-07:00 Serotonin modulates diverse phenotypes and functions including depressive, aggressive, impulsive, and feeding behaviors, all of which have reward-related components. To date, research has focused on understanding these effects by measuring and manipulating dorsal raphe serotonin neurons and using single-receptor approaches. These studies have led to a better understanding of the heterogeneity of serotonin actions on behavior; however, they leave open many questions about the timing and location of serotonin's actions modulating the neural circuits that drive these behaviors. Recent advances in genetically encoded fluorescent biosensors, including the GPCR activation-based sensor for serotonin (GRAB-5-HT), enable the measurement of serotonin release in mice on a timescale compatible with a single rewarding event without corelease confounds. Given substantial evidence from slice electrophysiology experiments showing that serotonin influences neural activity of the striatal circuitry, and the known role of the dorsal medial striatal (DMS) in reward-directed behavior, we focused on understanding the parameters and timing that govern serotonin release in the DMS in the context of reward consumption, external reward value, internal state, and cued reward. Overall, we found that serotonin release is associated with each of these and encodes reward anticipation, value, approach, and consumption in the DMS. Full Article
signals Cortically Disparate Visual Features Evoke Content-Independent Load Signals during Storage in Working Memory By www.jneurosci.org Published On :: 2024-10-30T09:30:22-07:00 It is well established that holding information in working memory (WM) elicits sustained stimulus-specific patterns of neural activity. Nevertheless, here we provide evidence for a distinct class of neural activity that tracks the number of individuated items in working memory, independent of the type of visual features stored. We present two EEG studies of young adults of both sexes that provide robust evidence for a signal tracking the number of individuated representations in working memory, regardless of the specific feature values stored. In Study 1, subjects maintained either colors or orientations across separate blocks in a single session. We found near-perfect generalization of the load signal between these two conditions, despite being able to simultaneously decode which feature had been voluntarily stored. In Study 2, participants attended to two features with very distinct cortical representations: color and motion coherence. We again found evidence for a neural load signal that robustly generalized across these distinct visual features, even though cortically disparate regions process color and motion coherence. Moreover, representational similarity analysis provided converging evidence for a content-independent load signal, while simultaneously showing that unique variance in EEG activity tracked the specific features that were stored. We posit that this load signal reflects a content-independent "pointer" operation that binds objects to the current context while parallel but distinct neural signals represent the features that are stored for each item in memory. Full Article
signals Anterior Olfactory Cortices Differentially Transform Bottom-Up Odor Signals to Produce Inverse Top-Down Outputs By www.jneurosci.org Published On :: 2024-10-30T09:30:22-07:00 Odor information arrives first in the main olfactory bulb and is then broadcasted to the olfactory cortices and striatum. Downstream regions have unique cellular and connectivity architectures that may generate different coding patterns to the same odors. To reveal region-specific response features, tuning and decoding of single-unit populations, we recorded responses to the same odors under the same conditions across regions, namely, the main olfactory bulb (MOB), the anterior olfactory nucleus (AON), the anterior piriform cortex (aPC), and the olfactory tubercle of the ventral striatum (OT), of awake male mice. We focused on chemically closely related aldehydes that still create distinct percepts. The MOB had the highest decoding accuracy for aldehydes and was the only region encoding chemical similarity. The MOB had the highest fraction of inhibited responses and narrowly tuned odor-excited responses in terms of timing and odor selectivity. Downstream, the interconnected AON and aPC differed in their response patterns to the same stimuli. While odor-excited responses dominated the AON, the aPC had a comparably high fraction of odor-inhibited responses. Both cortices share a main output target that is the MOB. This prompted us to test if the two regions convey also different net outputs. Aldehydes activated AON terminals in the MOB as a bulk signal but inhibited those from the aPC. The differential cortical projection responses generalized to complex odors. In summary, olfactory regions reveal specialized features in their encoding with AON and aPC differing in their local computations, thereby generating inverse net centrifugal and intercortical outputs. Full Article
signals The Effect of Congruent versus Incongruent Distractor Positioning on Electrophysiological Signals during Perceptual Decision-Making By www.jneurosci.org Published On :: 2024-11-06T09:30:07-08:00 Key event-related potentials (ERPs) of perceptual decision-making such as centroparietal positivity (CPP) elucidate how evidence is accumulated toward a given choice. Furthermore, this accumulation can be impacted by visual target selection signals such as the N2 contralateral (N2c). How these underlying neural mechanisms of perceptual decision-making are influenced by the spatial congruence of distractors relative to target stimuli remains unclear. Here, we used electroencephalography (EEG) in humans of both sexes to investigate the effect of distractor spatial congruency (same vs different hemifield relative to targets) on perceptual decision-making. We confirmed that responses for perceptual decisions were slower for spatially incongruent versus congruent distractors of high salience. Similarly, markers of target selection (N2c peak amplitude) and evidence accumulation (CPP slope) were found to be lower when distractors were spatially incongruent versus congruent. To evaluate the effects of congruency further, we applied drift diffusion modeling to participant responses, which showed that larger amplitudes of both ERPs were correlated with shorter nondecision times when considering the effect of congruency. The modeling also suggested that congruency's effect on behavior occurred prior to and during evidence accumulation when considering the effects of the N2c peak and CPP slope. These findings point to spatially incongruent distractors, relative to congruent distractors, influencing decisions as early as the initial sensory processing phase and then continuing to exert an effect as evidence is accumulated throughout the decision-making process. Overall, our findings highlight how key electrophysiological signals of perceptual decision-making are influenced by the spatial congruence of target and distractor. Full Article
signals Glucocorticoids Rapidly Modulate CaV1.2-Mediated Calcium Signals through Kv2.1 Channel Clusters in Hippocampal Neurons By www.jneurosci.org Published On :: 2024-11-06T09:30:07-08:00 The precise regulation of Ca2+ signals plays a crucial role in the physiological functions of neurons. Here, we investigated the rapid effect of glucocorticoids on Ca2+ signals in cultured hippocampal neurons from both female and male rats. In cultured hippocampal neurons, glucocorticoids inhibited the spontaneous somatic Ca2+ spikes generated by Kv2.1-organized Ca2+ microdomains. Furthermore, glucocorticoids rapidly reduced the cell surface expressions of Kv2.1 and CaV1.2 channels in hippocampal neurons. In HEK293 cells transfected with Kv2.1 alone, glucocorticoids significantly reduced the surface expression of Kv2.1 with little effect on K+ currents. In HEK293 cells transfected with CaV1.2 alone, glucocorticoids inhibited CaV1.2 currents but had no effect on the cell surface expression of CaV1.2. Notably, in the presence of wild-type Kv2.1, glucocorticoids caused a decrease in the surface expression of CaV1.2 channels in HEK293 cells. However, this effect was not observed in the presence of nonclustering Kv2.1S586A mutant channels. Live-cell imaging showed that glucocorticoids rapidly decreased Kv2.1 clusters on the plasma membrane. Correspondingly, Western blot results indicated a significant increase in the cytoplasmic level of Kv2.1, suggesting the endocytosis of Kv2.1 clusters. Glucocorticoids rapidly decreased the intracellular cAMP concentration and the phosphorylation level of PKA in hippocampal neurons. The PKA inhibitor H89 mimicked the effect of glucocorticoids on Kv2.1, while the PKA agonist forskolin abrogated the effect. In conclusion, glucocorticoids rapidly suppress CaV1.2-mediated Ca2+ signals in hippocampal neurons by promoting the endocytosis of Kv2.1 channel clusters through reducing PKA activity. Full Article
signals News24 Business | Fed makes quarter point cut as Powell signals readiness to defy Trump if asked to resign By www.news24.com Published On :: Friday Nov 08 2024 16:28:18 The US Federal Reserve shrugged off concerns about the economic impact of Donald Trump's election victory and moved ahead with a quarter point cut Thursday. Full Article
signals read from text file with two values and represent that as voltage signals on two different port a and b By community.cadence.com Published On :: Fri, 24 Feb 2023 00:33:01 GMT i want to read from text file two values on two ports , i wrote that code, and i have that error that shown in the image below . and also the data in text file is shown as screenshot module read_file (a,b); electrical a,b;integer in_file_0,data_value, valid, count0,int_value; analog begin @(initial_step) begin in_file_0 = $fopen("/home/hh1667/ee610/my_library/read_file/data2.txt","r"); valid = $fscanf (in_file_0, "%b,%b" ,int_value,count0); end V(a) <+ int_value; V(b) <+ count0; end endmodule Full Article
signals Regarding the loading of waveform signals in the waveform windown using the tcl command By community.cadence.com Published On :: Mon, 26 Feb 2024 09:26:52 GMT Hello, I am trying to load some of the signals of the design saved in the signals.svwf to the waveform windown via the tcl file, I am using the following commands but nothing works, Can you please help -submit waveform loadsignals -using "Waveform 2" FB1.svwf but it gives me the below error -submit waveform new -reuse -name Waveforms Full Article
signals UVM debugging: How to save and load signals during an interactive session in Simvision By community.cadence.com Published On :: Thu, 07 Mar 2024 23:18:50 GMT Hello, I am aware of command script .svcf file that saves signals and loads them in while opening Simvision. I am wondering, if there is a way for saving signals while we are in an interactive session and loading them next time when we open Simvision interactively. Any ideas on how to do this? Thank you in advance. Swetha. C Full Article
signals Aldridge Railway Signals named Indigenous Exporter of the Year By www.austrade.gov.au Published On :: Fri, 25 Aug 2023 05:26:00 GMT First Nations business Aldridge Railway Signals was named Exporter of the Year at Supply Nation’s Supplier Diversity Awards. Full Article Latest from Austrade
signals Israel’s Moves to Ban UNRWA—Signals Uncertainty for Affected Palestinians By www.ipsnews.net Published On :: Tue, 05 Nov 2024 14:08:49 +0000 The decision of Israel’s parliament, the Knesset, to adopt two laws that would severely limit or outright ban UNRWA has the potential to set a dangerous precedent, where countries can simply implement their own justification to ban the activity of the United Nations, even if it violates their obligations under international humanitarian law. Even with […] Full Article Aid Armed Conflicts Development & Aid Editors' Choice Featured Headlines Human Rights Humanitarian Emergencies Middle East & North Africa Peace TerraViva United Nations Gaza IPS UN Bureau IPS UN Bureau Report Israel Palestine UNWRA
signals Health Tip: When Hip Pain Signals Bursitis By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Health Tip: When Hip Pain Signals BursitisCategory: Health NewsCreated: 8/26/2010 10:10:00 AMLast Editorial Review: 8/27/2010 12:00:00 AM Full Article
signals Evolutionary dynamics of polyadenylation signals and their recognition strategies in protists [RESEARCH] By genome.cshlp.org Published On :: 2024-10-29T06:46:07-07:00 The poly(A) signal, together with auxiliary elements, directs cleavage of a pre-mRNA and thus determines the 3' end of the mature transcript. In many species, including humans, the poly(A) signal is an AAUAAA hexamer, but we recently found that the deeply branching eukaryote Giardia lamblia uses a distinct hexamer (AGURAA) and lacks any known auxiliary elements. Our discovery prompted us to explore the evolutionary dynamics of poly(A) signals and auxiliary elements in the eukaryotic kingdom. We use direct RNA sequencing to determine poly(A) signals for four protists within the Metamonada clade (which also contains G. lamblia) and two outgroup protists. These experiments reveal that the AAUAAA hexamer serves as the poly(A) signal in at least four different eukaryotic clades, indicating that it is likely the ancestral signal, whereas the unusual Giardia version is derived. We find that the use and relative strengths of auxiliary elements are also plastic; in fact, within Metamonada, species like G. lamblia make use of a previously unrecognized auxiliary element where nucleotides flanking the poly(A) signal itself specify genuine cleavage sites. Thus, despite the fundamental nature of pre-mRNA cleavage for the expression of all protein-coding genes, the motifs controlling this process are dynamic on evolutionary timescales, providing motivation for future biochemical and structural studies as well as new therapeutic angles to target eukaryotic pathogens. Full Article
signals Consolidating roles of neuroimmune reflexes: specificity of afferent, central, and efferent signals in homeostatic immune networks [Special Section: Symposium Outlook] By genesdev.cshlp.org Published On :: 2024-10-16T07:18:56-07:00 Neural reflexes occupy a central role in physiological homeostasis. The vagus nerve is a major conduit for transmitting afferent and efferent signals in homeostatic reflex arcs between the body and the brain. Recent advances in neuroscience, immunology, and physiology have revealed important vagus nerve mechanisms in suppressing inflammation and treating rheumatoid arthritis and other autoimmune conditions. Numerous clinical trials indicate that there is significant benefit to vagus nerve stimulation therapy. Although many questions are still unanswered, it will be important, even necessary, to pursue answers that will be useful in guiding interventions to modulate immunological and physiological homeostasis. Full Article
signals Signals from exotic new stars could hide in gravitational wave data By www.newscientist.com Published On :: Thu, 03 Oct 2024 16:00:45 +0100 A computer simulation suggests that some collisions between exotic, hypothetical stars would make space-time ripple with detectable waves Full Article
signals AI can reveal what’s on your screen via signals leaking from cables By www.newscientist.com Published On :: Fri, 26 Jul 2024 13:00:09 +0100 Electromagnetic radiation leaking from the cable between your computer and monitor can be intercepted and decoded by AI to reveal what you are looking at Full Article
signals Wireless Signals That Predict Flash Floods By spectrum.ieee.org Published On :: Mon, 04 Nov 2024 19:00:04 +0000 Like many innovators, Hagit Messer-Yaron had a life-changing idea while doing something mundane: Talking with a colleague over a cup of coffee. The IEEE Life Fellow, who in 2006 was head of Tel Aviv University’s Porter School of Environmental Studies, was at the school’s cafeteria with a meteorological researcher. He shared his struggles with finding high-resolution weather data for his climate models, which are used to forecast and track flash floods.Predicting floods is crucial for quickly evacuating residents in affected areas and protecting homes and businesses against damage.Hagit Messer-YaronEmployer Tel Aviv UniversityTitle Professor emeritaMember grade Life FellowAlma mater Tel Aviv UniversityHer colleague “said researchers in the field had limited measurements because the equipment meteorologists used to collect weather data—including radar satellites—is expensive to purchase and maintain, especially in developing countries,” Messer-Yaron says.Because of that, she says, high-resolution data about temperature, air quality, wind speed, and precipitation levels is often inconsistent—which is a problem when trying to produce accurate models and predictions.An expert in signal processing and cellular communication, Messer-Yaron came up with the idea of using existing wireless communication signals to collect weather data, as communication networks are spread across the globe.In 2006 she and her research team developed algorithms that process and analyze data collected by communication networks to monitor rainfall. They measure the difference in amplitude of the signals transmitted and received by the systems to extract data needed to predict flash floods.The method was first demonstrated in Israel. Messer-Yaron is working to integrate it into communication networks worldwide.For her work, she received this year’s IEEE Medal for Environmental and Safety Technologies for “contributions to sensing of the environment using wireless communication networks.” The award is sponsored by Toyota.“Receiving an IEEE medal, which is the highest-level award you can get within the organization, was really a surprise, and I was extremely happy to [receive] it,” she says. “I was proud that IEEE was able to evaluate and see the potential in our technology for public good and to reward it.”A passion for teachingGrowing up in Israel, Messer-Yaron was interested in art, literature, and science. When it came time to choose a career, she found it difficult to decide, she says. Ultimately, she chose electrical engineering, figuring it would be easier to enjoy art and literature as hobbies.After completing her mandatory service in the Israel Defense Forces in 1973, she began her undergraduate studies at Tel Aviv University, where she found her passion: Signal processing.“Electrical engineering is a very broad topic,” she says. “As an undergrad, you learn all the parts that make up electrical engineering, including applied physics and applied mathematics. I really enjoyed applied mathematics and soon discovered signal processing. I found it quite amazing how, by using algorithms, you can direct signals to extract information.”She graduated with a bachelor’s degree in EE in 1977 and continued her education there, earning master’s and doctoral degrees in 1979 and 1984. She moved to the United States for a postdoctoral position at Yale. There she worked with IEEE Life Fellow Peter Schultheiss, who was known for his research in using sensor array systems in underwater acoustics.Inspired by Schultheiss’s passion for teaching, Messer-Yaron decided to pursue a career in academia. She was hired by Tel Aviv University as an electrical engineering professor in 1986. She was the first woman in Israel to become a full professor in the subject.“Being a faculty member at a public university is the best job you can do. I didn’t make a lot of money, but at the end of each day, I looked back at what I did [with pride].”For the next 14 years, she conducted research in statistical signal processing, time-delay estimation, and sensor array processing.Her passion for teaching took her around the world as a visiting professor at Yale, the New Jersey Institute of Technology, the Institut Polytechnique de Paris, and other schools. She collaborated with colleagues from the universities on research projects.In 1999 she was promoted to director of Tel Aviv University’s undergraduate electrical engineering program. A year later, she was offered an opportunity she couldn’t refuse: Serving as chief scientist for the Israeli Ministry of Science, Culture, and Sports. She took a sabbatical from teaching and for the next three years oversaw the country’s science policy.“I believe [working in the public sector] is part of our duty as faculty members, especially in public universities, because that makes you a public intellectual,” she says. “Working for the government gave me a broad view of many things that you don’t see as a professor, even in a large university.”When she returned to the university in 2004, Messer-Yaron was appointed as the director of the new school of environmental studies. She oversaw the allocation of research funding and spoke with researchers individually to better understand their needs. After having coffee with one researcher, she realized there was a need to develop better weather-monitoring technology. Hagit Messer-Yaron proudly displays her IEEE Medal for Environmental and Safety Technologies at this year’s IEEE Honors Ceremony. She is accompanied by IEEE President-Elect Kathleen Kramer and IEEE President Tom Couglin.Robb CohenUsing signal processing to monitor weatherBecause the planet is warming, the risk of flash floods is steadily increasing. Warmer air holds more water—which leads to heavier-than-usual rainfall and results in more flooding, according to the U.S. Environmental Protection Agency. Data about rainfall is typically collected by satellite radar and ground-based rain gauges. However, radar images don’t provide researchers with precise readings of what’s happening on the ground, according to an Ensia article. Rain gauges are accurate but provide data from small areas only.So Messer-Yaron set her sights on developing technology that connects to cellular networks close to the ground to provide more accurate measurements, she says. Using existing infrastructure eliminates the need to build new weather radars and weather stations.Communication systems automatically record the transmitted signal level and the received signal level, but rain can alter otherwise smooth wave patterns. By measuring the difference in the amplitude, meteorologists could extract the data necessary to track rainfall using the signal processing algorithms.In 2005 Messer-Yaron and her group successfully tested the technology. The following year, their “Environmental Monitoring by Wireless Communication Networks” paper was published in Science.The algorithm is being used in Israel in partnership with all three of the country’s major cellular service providers. Messer-Yaron acknowledges, however, that negotiating deals with cellular service companies in other countries has been difficult.To expand the technology’s use worldwide, Messer-Yaron launched a research network through the European Cooperation in Science and Technology (COST), called an opportunistic precipitation sensing network known as OPENSENSE. The group connects researchers, meteorologists, and other experts around the world to collaborate on integrating the technology in members’ communities.Monitoring the effects of climate changeSince developing the technology, Messer-Yaron has held a number of jobs including president of the Open University of Israel and vice chair of the country’s Council for Higher Education, which accredits academic institutions.She is maintaining her link with Tel Aviv University today as a professor emerita.“Being a faculty member at a public university is the best job you can do,” she says. “I didn’t make a lot of money, but at the end of each day, I looked back at what I did [with pride]. Because of the academic freedom and the autonomy I had, I was able to do many things in addition to teaching, including research.” To continue her work in developing technology to monitor weather events, in 2016, she helped found ClimaCell, now Tomorrow.io, based in Boston. The startup aims to use wireless communication infrastructure and IoT devices to collect real-time weather data. Messer-Yaron served as its chief scientist until 2017.She continues to update the original algorithms with her students, most recently with machine learning capabilities to extract data from physical measurements of the signal level in communication networks.A global engineering communityWhen Messer-Yaron was an undergraduate student, she joined IEEE at the suggestion of one of her professors. “I didn’t think much about the benefits of being a member until I became a graduate student,” she says. “I started attending conferences and publishing papers in IEEE journals, and the organization became my professional community.”She is an active volunteer and a member of the IEEE Signal Processing Society. From 1994 to 2010 she served on the society’s Signal Processing Theory and Methods technical committee. She was associate editor of IEEE Signal Processing Letters and IEEE Transactions on Signal Processing. She is a member of the editorial boards of the IEEE Journal of Selected Topics in Signal Processing and IEEE Transactions on Signal Processing.In the past 10 years, she’s been involved with other IEEE committees including the conduct review, ethics and member conduct, and global public policy bodies.“I don’t see my career or my professional life without the IEEE,” she says Full Article Climate change Climate tech Ieee awards Ieee member news Signal processing Type:ti
signals California RD plant signals later start up By www.argusmedia.com Published On :: 12 Nov 2024 17:42 GMT Full Article Emissions Renewable Diesel LCFS CO2 US Corporate Net zero Supply Environmental politics