reactions

Chiral guanidine catalyzed cyclization reactions of 1,3-enynes for lactone synthesis: switchable H-bond catalysis

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00374H, Research Article
Yongyan Zhang, Lichao Ning, Tianxin Zhu, Zheng Xie, Shunxi Dong, Xiaoming Feng, Xiaohua Liu
Cyclization and 1,4-conjugate addition/cyclization between 2-activated 1,3-enynes and azlactones were achieved with chiral guanidine-amides for enol-type activation to yield a range of δ-lactone derivatives.
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reactions

Enantioselective synthesis of 8-membered lactone derivatives via organocatalytic cascade reactions

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00148F, Research Article
Dong-Sheng Ji, Rui Zhang, Xu-Yan Han, Hai-Long Chai, Yucheng Gu, Xiu-Qin Hu, Peng-Fei Xu
The challenging 8-membered lactone derivatives bearing two vicinal chiral stereocenters were synthesized via a cascade reaction mediated by the chiral squaramide.
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reactions

Cyclization reactions of 1,6-dienes and 1,6-enynes by dual cobalt photocatalysis

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00311J, Research Article
Pei-Ting Li, Zi-Fa Shi, Wei Yu
Two triphenylamine-derived organophotocatalysts were developed. Their photocatalytic capacity was exploited to enable the [CoIII]-H-mediated cycloisomerization of 1,6-dienes and reductive cyclization of 1,6-enynes under visible light irradiation.
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reactions

Unprecedented single-electron-transfer reduction-based N → C acyl migration reactions of imides enabled by redox-neutral photocatalysis

Org. Chem. Front., 2024, 11,2344-2350
DOI: 10.1039/D3QO01955A, Research Article
Linge Huai, Li Zhang, Zhentao Wang, Yewen Fang
N → C acyl migration: in the absence of a base, redox-neutral photocatalyzed acyl migration reactions have been realized via the reaction of N-vinylimides with alkyl radicals derived from alkyl silicates.
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reactions

Fe-catalyzed B–H and Si–H insertion reactions of gem-dihaloalkanes

Org. Chem. Front., 2024, 11,2241-2248
DOI: 10.1039/D4QO00136B, Research Article
Xinyu Wang, Zhaobin Wang
We present an approach involving Fe-catalyzed B–H and Si–H insertion of gem-dichloroalkanes. In contrast to previous strategies, our method uses gem-dihaloalkanes as non-stabilized carbene precursors and operates through a radical reaction pathway.
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reactions

Selective deletion of one carbon atom from C60 through benzylamine mediated reactions

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00449C, Research Article
Yaqiong Wang, Yiran Wu, Yuming Yu, Jie Su, Yi Qiu, Liangbing Gan
Benzylamine selectively adds to one of the two carbonyl groups on the 9-membered orifice to form an N,O-aminal moiety. Subsequent oxidation and hydrogen atom transfer lead to a decarboxylation process and formation of a nor [59]fullerene derivative.
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reactions

Substituent-controlled divergent cyclization reactions of benzo[c][1,2]dithiol-3-ones and hexahydro-1,3,5-triazines

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00356J, Research Article
Bohao Zhang, Sifan He, Na Dong, Antong Zhu, Haojie Duan, Dunjia Wang, Yao Zhou
An unprecedented metal-free divergent cyclization reaction of benzo[c][1,2]dithiol-3-ones with hexahydro-1,3,5-triazines to assemble six- and eight-membered N-containing heterocycles has been developed.
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reactions

Contribution of an instructional module incorporating PhET simulations to Rwandan students' knowledge of chemical reactions, acids, and bases through social interactions

Chem. Educ. Res. Pract., 2024, Advance Article
DOI: 10.1039/D4RP00105B, Paper
Jean-Baptiste Ndagijimana, Jeannette Musengimana, Henriette Mushimiyimana, Evode Mukama, Olivier Habimana, Paulin Manirakiza, Jean Claude Dushimimana, Jean Pierre Alpha Munyaruhengeri, Samia Khan, Elizabeth Lakin
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reactions

Timed ticketed entry for Glacier National Park next summer brings mixed reactions




reactions

Reactions to Prop 127 outcome




reactions

COMING FULL CIRCLE WITH REACTIONS: UNDERSTANDING THE STRUCTURE AND CORRELATES OF TRAINEE REACTIONS THROUGH THE AFFECT CIRCUMPLEX

Research suggests that the structure of trainee reactions is captured with as few as one or as many as eleven dimensions. It is commonly understood that reactions contain both affective and cognitive components. To date, however, training research focuses largely on affective reactions that range from pleasant to unpleasant (i.e., valence). Here, we expand and further refine the construct of affective trainee reactions by including reactions that are more and less activating versions of pleasantness (e.g., excitement and calm, respectively) and unpleasantness (e.g., stress and boredom, respectively). We develop and validate a new measure based on this model and argue that the structure of affective reactions has implications for better understanding learning and course reputation outcomes. Results from a short online training indicate that reactions were best explained by four factors: pleasant activation (e.g., excitement), pleasant deactivation (e.g., calm), unpleasant activation (e.g., stress), and unpleasant deactivation (e.g., boredom). The relationships between these reactions and training outcomes suggest what is most beneficial for course reputation outcomes (i.e., pleasant activating reactions) may not benefit learning; what is most beneficial for learning (i.e., pleasant deactivating reactions) may benefit course reputation outcomes but slightly less so.





reactions

Are adverse reactions to vaccines recordable? OSHA updates COVID-19 FAQ list

Washington — OSHA is requiring the recording of adverse reactions to COVID-19 vaccines only when vaccination is required by the employer, the agency says in an addition to its series of frequently asked questions on protecting workers from exposure to the coronavirus.




reactions

Avoid allergic reactions to latex

For some workers, particularly those in the health care field who wear latex gloves to protect against transmittable diseases, exposure to latex can result in allergic reactions.




reactions

'If I tell them that I live near the neighborhood, they're like, oh are you poor?' Differences in young people's reactions to territorial stigma in the Helsinki metropolitan area, Finland.

Children's Geographies; 10/01/2024
(AN 180134754); ISSN: 14733285
Academic Search Premier




reactions

'Point of no return': 5 reactions to rioters hunting down, attacking Israelis in Amsterdam

Rioters in the same city where Anne Frank hid during the Holocaust hunted down Israeli soccer fans, beating them and forcing them to say “Free Palestine” in an outbreak of violence that many have likened to Kristallnacht during the Nazi regime in Germany. 




reactions

'Justice for Peanut': 5 reactions to killing of celebrity squirrel seized by New York authorities

Peanut the squirrel’s seizure and euthanization by New York officials has sparked blowback from President Donald Trump’s running mate and various public figures, with the deceased pet now serving as the inspiration for a new law intended to improve animal rights. 




reactions

9 Christian leaders' reactions to Trump’s reelection as 47th president of the United States

In a historic political comeback on Tuesday, former President Donald Trump was reelected for a second, nonconsecutive term to serve as the 47th president of the United States, and he has promised to “help our country heal” after a bruising campaign during which he escaped two assassination attempts.




reactions

SEC Chair Gary Gensler's Remarks on Crypto: Industry Reactions and Implications

Hear From Crypto Vets




reactions

Robots can trick us into thinking we are socially interacting and slow our reactions, scientists say

Robots can trick us into thinking we are socially interacting and slow our reactions, scientists say




reactions

Quinoxalines Synthesis, Reactions, Mechanisms and Structure

Location: Electronic Resource- 




reactions

10 observations and overreactions after Gonzaga's opening night win over Baylor

There's starting off on the right foot, and then there's whatever happened Monday night inside Spokane Arena. The Gonzaga men's basketball team loudly announced itself as a national title contender late on college basketball's opening night with a dominating 101-63 win against Baylor…




reactions

Labor Election Reactions | Election Impact on the LGBTQ+ and Arts Communities | W. Kamau Bell at the Mondavi Center

How Election Day results on the federal, state, and local level impact the labor, arts, and LGBTQ+ communities. Finally, comedian W. Kamau Bell performs at the Mondavi Center at UC Davis.




reactions

5 takeaways from Colorado’s 2024 election — including reactions as a new Trump era looms

Tuesday's election offered a wide range of results to digest, both in Colorado and nationally -- at times going in different directions. Here are major takeaways from voters' decisions.




reactions

Top Memes And Reactions To Last Night's Democratic Presidential Debate

Why do politics always make for the best meme material? We'll just let the politicians speak for themselves. 

In case you missed last night's democratic presidential debate, then we'll give you a little run down: Cory Booker accused Joe Biden of being high, Amy Klobuchar claimed she raised a crap-load of money from her ex-boyfriends, and Biden made an, uh, brain-dead comment about domestic violence. 

Scroll down to watch some of the highlights and view some of the internet's reactions!





reactions

Human glucocerebrosidase mediates formation of xylosyl-cholesterol by {beta}-xylosidase and transxylosidase reactions.

Daphne E.C. Boer
Dec 23, 2020; 0:jlr.RA120001043v1-jlr.RA120001043
Research Articles




reactions

Human glucocerebrosidase mediates formation of xylosyl-cholesterol by {beta}-xylosidase and transxylosidase reactions. [Research Articles]

Deficiency of glucocerebrosidase (GBA), a lysosomal β-glucosidase, causes Gaucher disease. The enzyme hydrolyzes β-glucosidic substrates and transglucosylates cholesterol to cholesterol-β-glucoside. Here we show that recombinant human GBA also cleaves β-xylosides and transxylosylates cholesterol. The xylosyl-cholesterol formed acts as acceptor for subsequent formation of di-xylosyl-cholesterol. Common mutant forms of GBA from patients with Gaucher disease with reduced β-glucosidase activity were similarly impaired in β-xylosidase, transglucosidase and transxylosidase activities, except for a slightly reduced xylosidase/glucosidase activity ratio of N370S GBA and a slightly reduced transglucosylation/glucosidase activity ratio of D409H GBA. XylChol was found to be reduced in spleen from Gaucher disease patients. The origin of newly identified XylChol in mouse and human tissues was investigated. Cultured human cells exposed to exogenous β-xylosides generated XylChol in a manner dependent on active lysosomal GBA but not the cytosol-facing β-glucosidase GBA2. We later sought an endogenous β-xyloside acting as donor in transxylosylation reactions, identifying xylosylated ceramide (XylCer) in cells and tissues that serve as donor in the formation of XylChol. UDP-glucosylceramide synthase (GCS) was unable to synthesize XylChol but could catalyse formation of XylCer. Thus, food-derived β-D-xyloside and XylCer are potential donors for the GBA-mediated formation of XylChol in cells. The enzyme GCS produces XylCer at a low rate. Our findings point to further catalytic versatility of GBA and prompt a systematic exploration of the distribution and role of xylosylated lipids.




reactions

More user control may help ease negative reactions to ads on voice assistants

Voice assistants (VAs) like Alexa and Siri continue to gain popularity in households and on personal devices. According to digital trends research company Emarketer, the number of VA users will surpass 150 million in 2025. Despite the ubiquity, companies haven’t been able to work around users’ strong negative reactions to advertising on these applications. A research team, including scholars from Penn State, may have a solution.




reactions

Signal Updated With Call Links Feature, Raise Hand Button, Emoji Reactions and More Improvements

Signal has been updated with Call Links, a feature that enables users to initiate a group call with multiple participants without the need to form a separate group chat. Additional updates include a "raise hand" button, emoji reactions, and a dedicated calls tab on Signal.




reactions

One Savior, Five Reactions




reactions

Serious Reactions to Vaccines Rarely Recur: Review

Title: Serious Reactions to Vaccines Rarely Recur: Review
Category: Health News
Created: 8/28/2017 12:00:00 AM
Last Editorial Review: 8/28/2017 12:00:00 AM




reactions

Sukeban Games 2024 Interview: Christopher Ortiz AKA kiririn51 Talks .45 PARABELLUM BLOODHOUND, Inspirations, Fan Reactions, VA-11 Hall-A, The Silver Case, and Much More

Over the years, I’ve been able to interview some of my favorite developers ever including a few I never though …






reactions

Antibiotics and Severe Drug Reactions: A Closer Look

Commonly prescribed medlinkantibiotics/medlink, sulfonamides and cephalosporins, pose the highest risk for severe, potentially fatal skin reactions (!--ref1--).




reactions

'Miss Peregrine's Home...': Evokes Mixed Reactions

Layered with metaphors and allegories that give varied meanings to the narration, on the surface, the film is the adventure of a young boy named Jake (Asa Butterfield), who shuttles in time.




reactions

Seeing nanoscale electrocatalytic reactions at individual MoS2 particles under an optical microscope: probing sub-mM oxygen reduction reaction

Faraday Discuss., 2024, Advance Article
DOI: 10.1039/D4FD00132J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Nikan Afsahi, Zhu Zhang, Sanli Faez, Jean-Marc Noël, Manas Ranjan Panda, Mainak Majumder, Naimeh Naseri, Jean-François Lemineur, Frédéric Kanoufi
Interferometric scattering microscopy (iSCAT) allows visualizing individual petal-like MoS2 sub-microparticles and monitoring operando their activity towards oxygen reduction reaction.
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reactions

Retraction: Synthesis and characterization of a supported Pd complex on volcanic pumice laminates textured by cellulose for facilitating Suzuki–Miyaura cross-coupling reactions

RSC Adv., 2024, 14,12463-12463
DOI: 10.1039/D4RA90042A, Retraction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Siavash Salek Soltani, Reza Taheri-Ledari, S. Morteza F. Farnia, Ali Maleki, Alireza Foroumadi
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reactions

The untold story of starch as a catalyst for organic reactions

RSC Adv., 2024, 14,12676-12702
DOI: 10.1039/D4RA00775A, Review Article
Open Access
Masoud Sadeghi
Starch as catalyst for organic reactions.
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reactions

Effects of external light in the magnetic field-modulated photocatalytic reactions in a microfluidic chip reactor

RSC Adv., 2024, 14,13053-13061
DOI: 10.1039/D4RA00415A, Paper
Open Access
Hung Ji Huang, Yen Han Wang, Xuan-Yu Shih, Sy-Hann Chen, Hai-Pang Chiang, Yuan-Fong Chou Chau, Jeffrey Chi-Sheng Wu
Mutual enhancement of plasmonic photocatalytic reaction by both magnetic field and plasmonic enhancement was presented through Au–TiO2 nanoparticles.
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reactions

Exploring the synthetic potential of epoxide ring opening reactions toward the synthesis of alkaloids and terpenoids: a review

RSC Adv., 2024, 14,13100-13128
DOI: 10.1039/D4RA01834F, Review Article
Open Access
Madiha Hanif, Ameer Fawad Zahoor, Muhammad Jawwad Saif, Usman Nazeer, Kulsoom Ghulam Ali, Bushra Parveen, Asim Mansha, Aijaz Rasool Chaudhry, Ahmad Irfan
Epoxides are oxygen containing three-membered heterocycles which can undergo ring opening reactions. These reactions have been significantly employed in the synthesis of alkaloids and terpenoids-based natural products.
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reactions

Chemically engineered exogenous organic reactions in living cells for in situ fluorescence imaging and biomedical applications

J. Mater. Chem. B, 2024, Advance Article
DOI: 10.1039/D4TB01925C, Review Article
Gang Song, Zhiwen Yang, Yiming Huang, Haotian Bai, Fengting Lv, Shu Wang
Key intracellular in situ synthesis processes, including the synthesis of near-infrared fluorescent dyes, intracellular oxidative cross-linking, polymerization, and bioorthogonal reactions, as well as their biomedical applications were summarized.
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reactions

Reference-free quantitative mass spectrometry in the presence of nonlinear distortion caused by in situ chemical reactions among constituents

Analyst, 2024, 149,5320-5328
DOI: 10.1039/D4AN00961D, Paper
Yusuke Hibi
Nonlinear reference-free analysis in pyrolysis-MS enables accurate compositional analysis even in reactive and interactive systems.
The content of this RSS Feed (c) The Royal Society of Chemistry




reactions

Acoustic levitation and manipulation of columns of droplets with integrated optical detection for parallelisation of reactions

Analyst, 2024, 149,5546-5554
DOI: 10.1039/D4AN01096E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ruchi Gupta, Nicholas J. Goddard
In this work, acoustically levitated droplets serve as wells of microtitre plates and are acoustically manipulated to perform chemical and biological reactions in a non-contact fashion.
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reactions

Comparing coupled cluster and composite quantum chemical methods for computing activation energies and reaction enthalpies of radical propagation reactions

Phys. Chem. Chem. Phys., 2024, 26,27536-27543
DOI: 10.1039/D4CP03676J, Paper
Timothy B. Huber, Ralph A. Wheeler
The accuracy of DLPNO-CCSD(T)/CBS and composite methods G3(MP2)-RAD and CBS-RAD is assessed against CCSD(T)/aug-cc-pVTZ for activation energies and reaction enthalpies in hydrocarbon radical addition reactions relevant to free radical polymerization.
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reactions

Radical reactions enabled by polyfluoroaryl fragments: photocatalysis and beyond

Chem. Soc. Rev., 2024, Advance Article
DOI: 10.1039/D3CS00889D, Review Article
Mikhail O. Zubkov, Alexander D. Dilman
The review summarizes advances in the radical chemistry of polyfluorinated arenes under photocatalytic conditions. The fluoroaryl fragment serves as enabling motif for the reaction design and efficient generation of reactive intermediates.
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reactions

Recent Advances in Photochemical Strain-Release Reactions of Bicyclo[1.1.0]butanes

Chem. Commun., 2024, Accepted Manuscript
DOI: 10.1039/D4CC05108D, Highlight
Xiang Zhou, Ye Hu, Yao Huang, Yang Xiong
Bicyclo[1.1.0]butanes (BCBs) are attractive compounds for their beautiful “butterfly” conformations, distinctive properties, and novel reactivities. As soon as the first example had been synthesized, a wide range of strain-release reactions...
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reactions

Exogenous analogues of substance P trigger pseudo-allergic reactions through activation of MRGPRX2

New J. Chem., 2024, Advance Article
DOI: 10.1039/D3NJ04581A, Paper
Yi Shan, Jiayu Lu, Na Li, Xiaoxue Mo, Cheng Wang, Huaizhen He
This article reports that exogenous analogues of the neuropeptide substance P can activate MRGPRX2 to trigger pseudo-allergic reactions.
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reactions

Mechanochemical synthesis of biphenyl-derived organic fluorescent materials via solvent-free and ligand-free oxidative homocoupling reactions

New J. Chem., 2024, 48,7356-7361
DOI: 10.1039/D4NJ00886C, Paper
Zefeng Li, Caihang Zhang, Yingxuan Zheng, Ping Deng, Yan Yu
The palladium-catalyzed solvent-free and ligand-free oxidative homocoupling reactions of aryl boronic acids via ball-milling are developed to synthesize a series of biphenyl-derived organic fluorescent materials.
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