gates

Delegates to get preferential rates when using University of Aberdeen Sports facilities

The University of Aberdeen Sport and Recreation department are able to offer all delegates preferential rates for using the Sports facilities for the duration of the conference. [11 July 2008]




gates

Bill Clinton addresses AIDS 2014 delegates in Melbourne

Former US President Bill Clinton has told delegates at the 20th International AIDS Conference, AIDS 2014 in Melbourne, that finding more economically efficient ways to respond to HIV is vital to saving lives and preventing the spread of the virus. Mr Clinton’s speech was made to over 2,000 people at one of the most eagerly anticipated sessions at the AIDS 2014 conference in Melbourne.




gates

NASA Investigates Laser-Beam Welding in a Vacuum for In-Space Manufacturing

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gates

University of Rochester investigates 'Wanted' posters accusing staff of Gaza war crimes

The posters, which appeared across campus, accuse university faculty of being complicit in war crimes against Palestinians in Gaza. The university president condemned the posters as antisemitic.




gates

Discovery of hybrid Glypromate conjugates with neuroprotective activity against paraquat-induced toxicity

RSC Med. Chem., 2024, 15,3711-3727
DOI: 10.1039/D4MD00584H, Research Article
Sara C. Silva-Reis, Vera M. Costa, Daniela Correia da Silva, David M. Pereira, Xavier Cruz Correia, Xerardo García-Mera, José E. Rodríguez-Borges, Ivo E. Sampaio-Dias
A series of bicyclic-based Glypromate conjugates with reduction of protein aggregation elicited by Aβ25–35 and neuroprotective activity against paraquat-induced toxicity is reported, paving the way for the discovery of novel neurotherapeutics.
The content of this RSS Feed (c) The Royal Society of Chemistry




gates

Hydrophobic CPP/HDO conjugates: a new frontier in oligonucleotide-warheaded PROTAC delivery

RSC Med. Chem., 2024, 15,3695-3703
DOI: 10.1039/D4MD00546E, Research Article
Miyako Naganuma, Nobumichi Ohoka, Motoharu Hirano, Daishi Watanabe, Genichiro Tsuji, Takao Inoue, Yosuke Demizu
A novel hydrophobic cell-penetrating peptide (CPP) and heteroduplex oligonucleotide (HDO)-conjugated PROTAC, CPP/HDO-PROTAC, was designed to enhance its intracellular delivery and degradation efficiency.
The content of this RSS Feed (c) The Royal Society of Chemistry




gates

India To Be Most Digitized Economy In 7 Years: Gates

Noting that India has great potential to become the most digitized economy globally in mere seven years, Microsoft founder Bill Gates has dubbed the government's demonetization measure as a "bold move".




gates

Jesus Walk 2012 -- Bible verse: Psalms 118:19-29 ... Open to me the gates of righteousness [the resurrection of Jesus Christ]: I will go into them, and I will praise the LORD: This gate of the LORD, into which the righteous shall enter. I will praise thee

Psalms 118:19-29 Open to me the gates of righteousness: I will go into them, and I will praise the LORD: This gate of the LORD, into which the righteous shall enter. I will praise thee: for thou hast heard me, and art become my Salvation. The stone which the builders refused is become the head stone of the corner. This is the LORD'S doing; it is marvellous in our eyes. This is the day which the LORD hath made; we will rejoice and be glad in it. Save now, I beseech thee, O LORD: O LORD, I beseech thee, send now prosperity [lit. wellbeing]. Blessed be He (Jesus) that cometh in the Name of the LORD: we have blessed you out of the House of the LORD. God is the LORD, which hath shewed us [resurrection - sunrise] light: bind the sacrifice with cords, even unto the horns of the altar. Thou art my God, and I will praise thee: thou art my God, I will exalt thee. O give thanks unto the LORD; for He is good: for His mercy endureth for ever. -- Holy Bible



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gates

German Federal Chancellor Scholz, WHO Director-General Dr Tedros and Bill Gates at the World Health Summit 2024

The world's leading global health conference begins on October 13.




gates

Synthetic Aggregates Market is dominated by the Concrete sector, as per Maximize Market Research

(EMAILWIRE.COM, October 29, 2024 ) Global Synthetic Aggregates Market size is expected to grow at a CAGR of 3.7% throughout the forecast period, reaching nearly US$ 56.19 Bn. by 2030 Synthetic Aggregates Market overview Synthetic aggregates, also referred to as artificial aggregates or lightweight...





gates

The Three Entry Gates for Lust

We often gather our forces to fight our spiritual enemies at the wrong 'gate' of our being. Most frequently, evil enters our life through the gates of our mind and heart, not that of the body. We need to pay attention and learn the behaviour of the evil one, so we may guard well the fortress of our being. Once we learn to decode his behaviour, we can finally begin to plan a strategy to fight back.




gates

Open to Me the Gates of Repentance

Fr. Pat offers three reflections on the parable of the Publican and the Pharisee.




gates

Bash on Heaven's Gates! Be like that Canaanite Woman. Get your prayers right.

Don't let your prayers be little and timid but straight from your heart. 2 Corinthians 6: 16 - 18, 7:1 Matthew 15: 21 - 28




gates

TCS Group investigates cracks at J Satine mixed development project

KUALA LUMPUR: Building and infrastructure construction services provider TCS Group Holdings Bhd (TGB), as the main contractor via its wholly-owned subsidiary, TCS Construction Sdn Bhd (TCSB), for the J Satine mixed development project, has clarified the recent incident involving cracks in the building.

TGB managing director Datuk Ir Tee Chai Seng expressed concern about the incident and said the company is working closely with the developer and consultants to determine the root cause.

“Thankfully, there were no casualties as a result of the incident. We want to reiterate that health and safety have always been paramount in our projects.

“We want to assure all stakeholders that we have adhered strictly to all health and safety standards and protocols throughout the construction process,“ he said in a statement.

Tee said the group is cooperating fully with the relevant authorities to investigate the cause of the incident.

“Initial findings suggest that we do not cause the building cracks.

“For all our projects, we are committed to ensuring the safety and well-being of all involved and to deliver projects that meet the highest standards of quality and integrity,” Tee added.

He urged the cooperation from the public to stop sharing any unauthorised videos or images and speculating any unverified information related to this project development.




gates

Industrial safety gates

Mezzanine Safeti-Gates Inc. has expanded the power operation and technology offerings that can be added to its safety gate product line to save time and provide efficiencies when lift trucks are transferring material to and from upper levels.




gates

Pallet drop safety gates

Mezzanine Safeti-Gates Inc. has extended options for power, remote operation and tracking through its full line of pallet drop safety gates. New configurations work within the flow of a facility’s applications, offer no-touch environments and have custom engineered designs.




gates

Avoid injuries when using liftgates

Severed fingers and toes are injuries commonly associated with using truck liftgates. So are crushed feet.




gates

FDA Investigates Elevated Lead in Cinnamon Apple Pouches

FDA has initiated an onsite inspection at the Austrofoods facility located in Ecuador.




gates

Enhancing the strength of sandcrete blocks using coarse aggregates

This current article explores the possibility of adding aggregate (10 mm size) to sandcrete mixes in order to enhance the strength of the sandcrete blocks. Four different kinds of mixes were made; the first one was used as a reference without the addition of course aggregate, and in the remaining three, course aggregates were added in percentages of 5, 10 and 15% by volume of the reference m...




gates

1.08.26: Primary Ad-maggedon, Celebrity Surrogates, FITN Interview Tips

Brady chats with NYT columnist and Dartmouth political scientist Brendan Nyhan about this week's avalanche of political ads. Then, two seasoned primary watchers weigh in on the celebrities (and non-celebrities) candidates call upon in the primary's waning weeks. Finally, a public radio host who's interviewed hundreds of primary candidates shares her strategy to get them to open up. #FITN #2016 #Politics




gates

The Bookshelf: Trans Girl Navigates Middle School in Exeter Author's New Novel

For many kids, middle school is a fraught time. Friendships are forged and broken; bodies begin to change in sometimes uncomfortable ways. For Zenobia July, starting middle school is far more complicated than it is for most of her peers.




gates

U.S. Chemical Safety Board investigates release of toxic hydrofluoric acid at Honeywell facility

This is the third serious incident involving the release of HF at the Louisiana facility in the last three years, official says.




gates

Whose Life Matters? Rev. Richard Klingeisen Navigates Vital Family Issues with Balance and Fairness in New Podumentary Episode, 'Choose Life'

Explore the thought-provoking release of 'Choose Life,' the latest episode from Rev. Richard Klingeisen's celebrated web series, 'A Life of Giving.' You can stream it right now at www.Klingeisen.com.




gates

KAILASA's Delegates at UNESCO's 15th International Forum of NGOs on "Transforming Mentalities"

Representatives of KAILASA Contribute to Global Dialogue Addressing Inequalities Within Societies




gates

Funwhole Announces the Launch of a Highly Innovative Steampunk Vintage Car. The vehicle not only allows for free opening of doors and boarding but also effortlessly navigates between day and night

Highlights of the product introduction.




gates

Beyond Our Gates Foundation of Kiawah and Seabrook Islands Grants $300,000 to 16 Charleston Nonprofits

The Grant Honors College of Charleston's First Black Woman Graduate, Linda Gadson




gates

Bill Gates on How Business Leaders Can Fight Climate Change

Bill Gates, philanthropist and founder of Microsoft, argues that, even as we work to end the global pandemic, we can't lose sight of another existential threat: climate change. He says that we need to take aggressive action to get to net zero carbon emissions by 2050 and insists that regulation isn't enough. Businesses need to pave the way forward by investing much more heavily in climate-friendly innovation. Gates speaks with HBR editor in chief Adi Ignatius about his new book, "How to Avoid a Climate Disaster: The Solutions We Have and the Breakthroughs We Need."





gates

ETSI’s Security Conference Navigates Next Generation Technologies

Sophia Antipolis, 19 October 2023

ETSI’s well-known Security Conference came to a close today with nearly 250 onsite attendees from 29 countries. This year’s event focused on security research and global security standards in action, considering broader aspects such as attracting the next generation of cybersecurity standardization professionals and supporting SMEs.

Read More...





gates

The Ethics of "Human Brain Surrogates"

The ethical questions raised by emerging neuro-technologies




gates

Legati, delegati e l’impresa d’Oltremare (secoli XII-XIII) = Papal Legates, Delegates and the Crusades (12th-13th Century): Atti del Convegno internazionale di studi Milano, Università Cattolica del Sacro Cuore, 9-11 marzo 2011

Location: Electronic Resource- 




gates

Bill Gates Makes Melinda a Billionaire on Day of Divorce Filing, Translator Denies Being Homewrecker

The Microsoft founder reportedly transferred $1.8 billion worth of stocks to his estranged wife on the same day they announced the end of their 27-year marriage.




gates

Bill Gates' Estranged Wife Agrees Not to Seek Spousal Support in $130 Billion Divorce Battle

Many on Twitter call out the Microsoft co-founder and his estranged wife Melinda Gates shortly after they made public their split, but they tag the wrong Melinda.




gates

Bill Gates Still Seeing Ex Ann Winblad While Married to Melinda

In light of the couple's split announcement, it's revealed that the Microsoft founder took private getaways with his ex-girlfriend and fellow nerd techie Ann at a cozy beach cottage in North Carolina.




gates

Bill Gates Makes Melinda a Billionaire on Day of Divorce Filing, Translator Denies Being Homewrecker

The Microsoft founder reportedly transferred $1.8 billion worth of stocks to his estranged wife on the same day they announced the end of their 27-year marriage.




gates

The Stranger in Your Gates (Lesson #5)

Loving your neighbor as yourself is the highest expression of God’s law.




gates

Yadira Caraveo, seeking reelection to Congress, navigates politics of abortion, immigration as some positions shift

As U.S. Rep. Yadira Caraveo emphasizes abortion rights in her reelection race in Colorado's battleground 8th Congressional District, she's moved the right on immigration -- angering some allies -- while facing fierce attacks from supporters of Republican challenger Gabe Evans.





gates

PLP Annual Delegates Conference On Oct 23

The Progressive Labour Party [PLP] is set to host its 59th Annual Delegates Conference on Wednesday [Oct 23], under the theme ‘The Power of One.’ A spokesperson said, “The event, which will be held at St. Paul A.M.E. Church, Centennial Hall, will run from 7:00 PM to 9:30 PM and promises an engaging lineup of […]




gates

Video: PLP Annual Delegates Conference

[Updated] The Progressive Labour Party [PLP] is holding their annual Delegates Conference this evening [Oct 23] at St. Paul A.M.E. Church, Centennial Hall, under the theme ‘The Power of One.’ PLP Party Chair Dawn Simmons previously said, “‘The Power of One’ reminds us that while individual contributions may seem small, together they create powerful change. […]




gates

New Daytime Drama Series "Beyond the Gates" to Premiere Monday, Feb. 24, 2025 on CBS

The series is set in a leafy Maryland suburb just outside of Washington, D.C., and in one the most affluent African American counties in the United States.




gates

Hot Gates




gates

A novel method produces native light-harvesting complex II aggregates from the photosynthetic membrane revealing their role in nonphotochemical quenching [Bioenergetics]

Nonphotochemical quenching (NPQ) is a mechanism of regulating light harvesting that protects the photosynthetic apparatus from photodamage by dissipating excess absorbed excitation energy as heat. In higher plants, the major light-harvesting antenna complex (LHCII) of photosystem (PS) II is directly involved in NPQ. The aggregation of LHCII is proposed to be involved in quenching. However, the lack of success in isolating native LHCII aggregates has limited the direct interrogation of this process. The isolation of LHCII in its native state from thylakoid membranes has been problematic because of the use of detergent, which tends to dissociate loosely bound proteins, and the abundance of pigment–protein complexes (e.g. PSI and PSII) embedded in the photosynthetic membrane, which hinders the preparation of aggregated LHCII. Here, we used a novel purification method employing detergent and amphipols to entrap LHCII in its natural states. To enrich the photosynthetic membrane with the major LHCII, we used Arabidopsis thaliana plants lacking the PSII minor antenna complexes (NoM), treated with lincomycin to inhibit the synthesis of PSI and PSII core proteins. Using sucrose density gradients, we succeeded in isolating the trimeric and aggregated forms of LHCII antenna. Violaxanthin- and zeaxanthin-enriched complexes were investigated in dark-adapted, NPQ, and dark recovery states. Zeaxanthin-enriched antenna complexes showed the greatest amount of aggregated LHCII. Notably, the amount of aggregated LHCII decreased upon relaxation of NPQ. Employing this novel preparative method, we obtained a direct evidence for the role of in vivo LHCII aggregation in NPQ.




gates

AggreCount: an unbiased image analysis tool for identifying and quantifying cellular aggregates in a spatially defined manner [Methods and Resources]

Protein quality control is maintained by a number of integrated cellular pathways that monitor the folding and functionality of the cellular proteome. Defects in these pathways lead to the accumulation of misfolded or faulty proteins that may become insoluble and aggregate over time. Protein aggregates significantly contribute to the development of a number of human diseases such as amyotrophic lateral sclerosis, Huntington's disease, and Alzheimer's disease. In vitro, imaging-based, cellular studies have defined key biomolecular components that recognize and clear aggregates; however, no unifying method is available to quantify cellular aggregates, limiting our ability to reproducibly and accurately quantify these structures. Here we describe an ImageJ macro called AggreCount to identify and measure protein aggregates in cells. AggreCount is designed to be intuitive, easy to use, and customizable for different types of aggregates observed in cells. Minimal experience in coding is required to utilize the script. Based on a user-defined image, AggreCount will report a number of metrics: (i) total number of cellular aggregates, (ii) percentage of cells with aggregates, (iii) aggregates per cell, (iv) area of aggregates, and (v) localization of aggregates (cytosol, perinuclear, or nuclear). A data table of aggregate information on a per cell basis, as well as a summary table, is provided for further data analysis. We demonstrate the versatility of AggreCount by analyzing a number of different cellular aggregates including aggresomes, stress granules, and inclusion bodies caused by huntingtin polyglutamine expansion.




gates

Intraneuronal beta-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Holly Oakley
Oct 4, 2006; 26:10129-10140
Neurobiology of Disease




gates

Intraneuronal beta-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Holly Oakley
Oct 4, 2006; 26:10129-10140
Neurobiology of Disease




gates

Meet the Italian 'Fruit Detective' Who Investigates Centuries-Old Paintings for Clues About Produce That Has Disappeared From the Kitchen Table

Renaissance paintings, medieval archives, cloistered orchards—how one Italian scientist is uncovering secrets that could help combat a growing agricultural crisis




gates

DOJ secures Manafort and Gates-connected entity dissolutions 

The Delaware Department of Justice secured Friday a Court of Chancery ruling dissolving four LLCs and two corporations owned by Paul J. Manafort, Jr. and Richard W. Gates, III after the Court approved an Order granting a default judgment. “This is another victory for the integrity of Delaware’s corporate brand,” said Attorney General Jennings. “Paul Manafort […]



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