Mid Cities Psychiatry has been awarded The Joint Commission's Gold Seal of Approval® for Behavioral Health Care and Human Services by powering through its performance standards.

Goal-directed visual attention is a fundamental cognitive process that enables animals to selectively focus on specific regions of the visual field while filtering out irrelevant information. However, given the domain specificity of social behaviors, it remains unclear whether attention to faces versus nonfaces recruits different neurocognitive processes. In this study, we simultaneously recorded activity from temporal and frontal nodes of the attention network while macaques performed a goal-directed visual search task. V4 and inferotemporal (IT) visual category-selective units, selected during cue presentation, discriminated fixations on targets and distractors during the search but were differentially engaged by face and house targets. V4 and IT category-selective units also encoded fixation transitions and search dynamics. Compared with distractors, fixations on targets reduced spike–LFP coherence within the temporal cortex. Importantly, target-induced desynchronization between the temporal and prefrontal cortices was only evident for face targets, suggesting that attention to faces differentially engaged the prefrontal cortex. We further revealed bidirectional theta influence between the temporal and prefrontal cortices using Granger causality, which was again disproportionate for faces. Finally, we showed that the search became more efficient with increasing target-induced desynchronization. Together, our results suggest domain specificity for attending to faces and an intricate interplay between visual attention and social processing neural networks.

The activation of autonomic and hypothalamo-pituitary-adrenal (HPA) systems occurs interdependently with behavioral adjustments under varying environmental demands. Nevertheless, laboratory rodent studies examining the neural bases of stress responses have generally attributed increments in these systems to be monolithic, regardless of whether an active or passive coping strategy is employed. Using the shock probe defensive burying test (SPDB) to measure stress-coping features naturalistically in male and female rats, we identify a neural pathway whereby activity changes may promote distinctive response patterns of hemodynamic and HPA indices typifying active and passive coping phenotypes. Optogenetic excitation of the rostral medial prefrontal cortex (mPFC) input to the ventrolateral periaqueductal gray (vlPAG) decreased passive behavior (immobility), attenuated the glucocorticoid hormone response, but did not prevent arterial pressure and heart rate increases associated with rats’ active behavioral (defensive burying) engagement during the SPDB. In contrast, inhibition of the same pathway increased behavioral immobility and attenuated hemodynamic output but did not affect glucocorticoid increases. Further analyses confirmed that hemodynamic increments occurred preferentially during active behaviors and decrements during immobility epochs, whereas pathway manipulations, regardless of the directionality of effect, weakened these correlational relationships. Finally, neuroanatomical evidence indicated that the influence of the rostral mPFC->vlPAG pathway on coping response patterns is mediated predominantly through GABAergic neurons within vlPAG. These data highlight the importance of this prefrontal->midbrain connection in organizing stress-coping responses and in coordinating bodily systems with behavioral output for adaptation to aversive experiences.

Asset Management Group, Inc. proudly announces the achievement of LeGrand S. Redfield, Jr. CLU, ChFC, CFP, who has successfully obtained the Accredited Behavioral Finance ProfessionalSM (ABFP™) designation from the renowned College for Financial Planning.

Aim/Purpose: The aim of this study was to explore the factors driving individuals’ behavioral intention to use cryptocurrency in Saudi Arabia using the extended TRA model. Background: Despite the great potential of cryptocurrencies and the exponential growth of cryptocurrency use throughout the world, scholarly research on this topic remained scarce. Whereas prior studies are mostly done in developed countries or specific cultural contexts, limiting the generalizability of their results, they mainly used technology adoption models that cannot fully explain the acceptance of new technology involved with financial transactions such as cryptocurrency and provided contradictory evidence. Entire regions have been excluded from the research on this topic, including Saudi Arabia which has a high potential to increase the volume of cryptocurrency use. Methodology: This study extends the theory of reasoned action (TRA) with the factors from technology adoption models that proved relevant for this topic, namely perceived usefulness, perceived enjoyment, perceived innovativeness, and perceived risk with three sub-factors: security, financial, and privacy risk. Data are collected using a quantitative research methodology from 181 respondents residing in Saudi Arabia and then analyzed by several methods, including exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and structural equation modeling (SEM). Contribution: This study contributes to the scientific knowledge by extending the TRA model with a range of factors from the technology adoption field, thus enabling the analysis of this topic from human, financial, and technology perspectives and providing additional empirical evidence on the factors that previously either provided contradictory evidence or were not explored in this field. This research also provides the first empirical data on this topic in Saudi Arabia and enables further research on the topic and a comparison of the results. The study also contributes to practice by enhancing the actual understanding of the phenomena and providing valuable information and recommendations for governments, investors, merchants, developers, and the general population. Findings: The study found attitude, subjective norm, perceived usefulness, perceived enjoyment, personal innovativeness, privacy risk, and financial risk as significant predictors of the intention to use cryptocurrencies, whereas the influence of security risk was not found to be significant in Saudi Arabia. Recommendations for Practitioners: Using this study’s results, governments can create appropriate legal frameworks, developers can design fewer complex platforms, and merchants may create appropriate campaigns that emphasize the benefits of cryptocurrency use and transpire trust in cryptocurrency transactions by enhancing the factors with a positive impact, such as usefulness, enjoyment, and personal innovativeness while reducing concerns of potential users regarding the risky factors. By promoting a positive user experience, they can also improve attitudes and social norms towards cryptocurrencies, thus further stimulating the interest in their use. Recommendation for Researchers: As this study validated the influence of factors from technology, financial, and human-related fields, researchers may follow this approach to ensure a comprehensive analysis of this complex topic, especially as privacy risk was never examined in this context, while personal innovativeness, perceived enjoyment, financial, and security risk were explored in just a few studies. It is also recommended that researchers explore the impact of each part of subjective norms: social media, friends, and family, as well as how information on the benefits of cryptocurrencies affects the perception of the factors included. Impact on Society: Understanding the factors affecting cryptocurrency use can help utilize the full potential of cryptocurrencies, especially their benefits for developing countries reflected in safe, speedy, and low-cost financial transactions with no need for an intermediary. The research model of this study could also be used to investigate this topic in other contexts to discover similarities and differences, as well as to investigate other information systems. Future Research: Future studies should test this research model in similar and different contexts to determine whether its validity and study results depend on cultural and contextual factors. They can also include different or additional variables, or use mixed methods, as interviews would augment the comprehension of this topic. Future studies may also explore whether the impact of variables would remain the same if circumstances changed or use cases expanded, and how the preferences of the target population would change within a longitudinal time frame.

Aim/Purpose: The primary purpose of this study is to investigate the factors that impact the behavioral intention to use social media (SM) for knowledge sharing (KS) in the disaster relief (DR) context. Background: With the continuing growth of SM for KS in the DR environment, disaster relief organizations across the globe have started to realize its importance in streamlining their processes in the post-implementation phase. However, SM-based KS depends on the willingness of members to share their knowledge with others, which is affected by several technological, social, and organizational factors. Methodology: A survey was conducted in Somalia to gather primary data from DR practitioners, using purposive sampling as the technique. The survey collected 214 valid responses, which were then analyzed with the PLS-SEM approach. Contribution: The study contributes to an understanding of the real-life hurdles faced by disaster relief organizations by expanding on the C-TAM-TPB model with the inclusion of top management support, organizational rewards, enjoyment in helping others, knowledge self-efficacy, and interpersonal trust factors. Additionally, it provides useful recommendations to managers of disaster relief organizations on the key factors to consider. Findings: The findings recorded that perceived usefulness, ease of use, top management support, enjoyment in helping others, knowledge self-efficacy, and interpersonal trust were critical factors in determining behavioral intention (BI) to use SM-based KS in the DR context. Furthermore, the mediator variables were attitude, subjective norms, and perceived behavioral control. Recommendations for Practitioners: Based on the research findings, it was determined that management should create different discussion forums among the disaster relief teams to ensure the long-term use of SM-based KS within DR organizations. They should also become involved in the discussions for disaster-related knowledge such as food supplies, shelter, or medical relief that disaster victims need. Disaster relief managers should consider effective and adequate training to enhance individual knowledge and self-efficacy since a lack of training may increase barriers and difficulties in using SM for KS during a DR process. Recommendation for Researchers: The conceptual model, further empirically investigated, can be employed by other developing countries in fostering acceptance of SM for KS during disaster relief operations. Impact on Society: Disaster relief operations can be facilitated using social media by considering the challenges DR practitioners face during emergencies. Future Research: In generalizing this study’s findings, other national or global disaster relief organizations should consider, when applying and testing, the research instruments and proposed model. The researchers may extend this study by collecting data from managers or administrators since they are different types of users of the SM-based KS system.

Aim/Purpose: This study aims to examine the ten factors from the Technology Acceptance Model (TAM), Theory of Planned Behavior (TPB), and Unified Theory of Acceptance and Use of Technology (UTAUT) theories in order to analyze behavioral intentions to use the Indonesian online capital market investment platforms and the effect of behavioral intentions on actual usage. Background: The potential growth of capital market investors in Indonesia is large, and the low use of the Internet for investment purposes makes it necessary for stakeholders to understand the factors that affect people’s intentions to invest, especially through online platforms. Several previous studies have explained the intention to use online investment platforms using the TAM and TPB theories. This study tries to combine TAM, TPB, and UTAUT theories in analyzing behavioral intentions to use an online capital market investment platform in Indonesia. Methodology: The research approach employed is a mixed method, particularly explanatory research, which employs quantitative methods first, followed by qualitative methods. Data were collected by conducting interviews and sending online surveys. This study was successful in collecting information on the users of online capital market investment platforms in Indonesia from 1074 respondents, which was then processed and analyzed using Covariance-Based Structural Equation Modeling (CB-SEM) with the IBM AMOS 26.0 application. Contribution: This study complements earlier theories like TAM, TPB, and UTAUT by looking at the intention to use online capital market investment platforms from technological, human, and environmental viewpoints. This study looks at the intention to use the online capital market investing platform as a whole rather than separately depending on investment instruments. This study also assists practitioners including regulators, the government, developers, and investors by offering knowledge of the phenomena and factors that can increase the capital market’s investment intention in Indonesia. Findings: Attitudes, perceived ease of use, perceived behavioral control, subjective norm, and national pride were found to be significant predictors of the intention to use online investment platforms in Indonesia, whereas perceived usefulness, perceived risk, perceived trust, perceived privacy, and price value were not. Recommendations for Practitioners: All practitioners must be able to take steps and strategies that focus on factors that have a significant impact on increasing usage intentions. The government can enact legislation that emphasizes the simplicity and convenience of investment, as well as launch campaigns that encourage people to participate in economic recovery by investing in the capital market. Meanwhile, the developers are concentrating on facilitating the flow of investment transactions through the platform, increasing education and awareness of the benefits of investing in the capital market, and providing content that raises awareness that investing in the capital market can help to restore the national economy. Recommendation for Researchers: Further research is intended to include other variables such as perceived benefits and perceived security, as well as other frameworks such as TRA, to better explain individuals’ behavioral intentions to use online capital investment platforms. Impact on Society: This study can help all stakeholders understand what factors can increase Indonesians’ interest in investing in the capital market, particularly through online investment platforms. This understanding is expected to increase the number of capital market participants and, as a result, have an impact on economic recovery following the COVID-19 pandemic. Future Research: Future research is expected to investigate additional factors that can influence individuals’ behavioral intention to use an online capital market investment platform, such as perceived benefits and perceived security, as well as the addition of control variables such as age, gender, education, and income. International research across nations is also required to build a larger sample size in order to examine the behavior of investors in developing and developed countries and acquire a more thorough understanding of the online capital market investment platform.

Personalization is one of the most expected features in the current educational systems. User modeling is supposed to be the first stage of this process, which may incorporate learning style as an important part of the model. Learning style, which is a non-stable characteristic in the case of children, differentiates students in learning preferences. This paper identifies a new hybrid method to initiate and update the information of children’s learning style in an educational system. At the start-up phase, children’s learning style information is gathered through the modified Murphy-Meisgeier Type Indicator for Children (MMTIC) questionnaire, which is based on the well-known Myers-Briggs Type Indicator (MBTI). This primary information will be tuned by tracking children’s behaviors during the learning process. Analytical data mining helped us to cluster these behaviors and find their patterns. The proposed method was applied on 81 fourth grade children in elementary school. Delivering results suggest that this method provides a good precision in recognizing children learning style and may be an appropriate solution for non-stability problems in their preferences.

Firms play a crucial role in furthering social welfare through their ability to foster stakeholders' contributions to joint value creation, i.e., value creation that involves a public-good dilemma due to high task and outcome interdependence - leading to what economists have labeled the 'team production problem'. We build on relational models theory to examine how individual stakeholders' contributions to joint value creation are shaped by stakeholders' mental representations of their relationships with the other participants in value creation, and how these mental representations are affected by the perceived behavior of the firm. Stakeholder theory typically contrasts a broadly-defined 'relational' approach to stakeholder management with a 'transactional' approach based on the price mechanism - and has argued that the former is more likely to contribute to social welfare than the latter. Our theory supports this prediction for joint value creation, but also implies that the dichotomy on which it is based is too coarse-grained: there are three distinct ways to trigger higher contributions to joint value creation than through a 'transactional' approach. Our theory also helps explain the tendency for firms and their stakeholders to converge on 'transactional' relationships, despite their relative inefficiency in the context of joint value creation.

Although there may be a pandemic-related slowdown, there’s no stopping new product development. To help readers with new product development strategy, Prepared Foods asked Dave Lundahl, founder of InsightsNow, to create a thought leadership series connecting R&D with consumer insights. 

The post Alternatives for Families: A Cognitive-Behavioral Therapy (AF-CBT) was curated by information for practice.

The post Commission makes nearly 20 legislative recommendations to address Indiana’s behavioral health needs was curated by information for practice.

American Journal of Men’s Health, Volume 18, Issue 5, September-October 2024. Hispanic men have the highest prevalence of obesity relative to other racial and ethnic subgroups; however, this population is consistently underrepresented in weight management interventions. This systematic review aims to provide an overview of behavioral weight management interventions adapted for Hispanic men and describe […]

The post Behavioral Weight Management Interventions for Hispanic Men in the United States: A Systematic Review was curated by information for practice.

The post U.S. Preventive Services Task Force seeks comments on Draft Recommendation Statement and Draft Evidence Review: Behavioral Counseling Interventions to Support Breastfeeding was curated by information for practice.

Behavioral economist Sendhil Mullainathan to join Booth faculty as University Professor

The social, behavioral, and economic (SBE) sciences make significant contributions to the National Science Foundation’s mission to advance health, prosperity and welfare, national defense, and progress in science, says a new report from the National Academies of Sciences, Engineering, and Medicine.

Our ability to observe and predict severe weather events and other disasters has improved markedly over recent decades, yet this progress does not always translate into similar advances in the systems used in such circumstances to protect lives.

The social and behavioral sciences (SBS) offer an essential contribution to the mission of the U.S. Intelligence Community (IC), a mission that requires an understanding of what human beings do, how, and why, says a new report by the National Academies of Sciences, Engineering, and Medicine.

A new report from the National Academies of Sciences, Engineering, and Medicine calls for a comprehensive national agenda to improve mental, emotional, and behavioral (MEB) health in children and youth. Despite advances in research, rates of depression, suicide and self-harm among young people have been increasing.

Following a national search, Carlotta M. Arthur will join the National Academies as the new executive director of the Division of Behavioral and Social Sciences and Education on Feb. 14.

A new National Academies report highlights how behavioral economics has built invaluable evidence about why people may act in seemingly irrational ways, how they respond to interventions, and how public policy can be designed to help people make better decisions.

Study Links Altered Brain Chemistry, Behavioral Impairments in Fish Exposed to Elevated CO2 Research team studied damselfish behavior and physiology under ocean acidification conditions predicted for year 2300

read more

Destiny King-M.A., BCBA, LBA, is dedicated to treating children with autism as the founder of Beauty and the Behavior LLC

Victoria Holland is a respected provider of therapeutic interventions and an expert in pediatric wellness protocols

Sydney Ceruto is an experienced brain-based coach, counselor and founder of MindLAB Neuroscience

Children who sustain an mTBI are at increased risk for developing new affective or behavioral disorders over four-years post-injury.

Event Begins: Wednesday, November 13, 2024 2:00pm
Location: LSA Building
Organized By: LSA Opportunity Hub

Interview jitters? The LSA Opportunity Hub is here to help. Participate in a mock interview with an employer representative to build up the confidence you need to nail your next interview! This is your chance to practice your interviewing skills and get real-time feedback from employers, ahead of the recruiting season. Hub coaches will also be on standby to provide drop-in coaching that can further fine-tune your interview preparation. Emerge from this session with the skills you need to rock any interview!

You should attend this Employer Connection if you are:



An LSA student in any year



An LSA student looking for extra interview practice and preparing for recruiting season



Eager to demystify and excel in behavioral and technical interviews



Eager to connect with employers and tap into their industry knowledge



What you’ll gain by attending:

Gain practical experience to confidently navigate the interview process



Get insights on how to effectively communicate your experiences and skills in a high-pressure interview setting



Use this opportunity to share your résumé with the respective recruiting teams



Make valuable connections with employers looking to hire LSA students



Companies will attend both virtually and in-person. Both will be held in the LSA 1st Floor interview rooms with virtual employers cast onto the screens. When signing up for a schedule slot, rooms containing virtual employers will be noted. Confirmed employers include:

TBD

The LSA Opportunity Hub aims to deliver inclusive and accessible experiences and welcomes all LSA students to participate. This event is on the first floor of a wheelchair accessible building which includes wheelchair-accessible restrooms on the first floor, a gender-inclusive and accessible restroom on the first floor, places to sit or stand during the event, and accessible parking options nearby on Maynard Street. Ramps are located at the East entrance (from State St.) and the Northwest entrance (from Maynard). Power doors are located at the Northwest entrance. To request other accommodations please contact LSA Hub Events at lsa.hubevents@umich.edu or 734-764-4920 so we can make arrangements.

RSVP NOW to reserve your spot as capacity is limited.

Adam Tornhill, founder and CTO of CodeScene, joins host Giovanni Asproni to speak about behavioral code analysis. Behavioral code analysis is a set of practical techniques aimed at identifying patterns in how a development organization interacts with the codebase they're building. It can be used to prioritize technical debt to maximize return on investment; to identify communication and team-coordination bottlenecks in code; to drive refactorings guided by data from how the system evolves; and to detect code quality problems before they become maintenance issues. The episode starts with a broad description of the techniques, providing some examples from real projects, and ends with suggestions on how to get started with applying them. During the conversation, Adam and Giovanni touch on a set of related topics, including the applicability of the techniques to legacy, green-, and brown-field projects; ethical and privacy implications; and the importance of context when judging code quality.

Location: Electronic Resource- 

Behavioral analytics, long associated with threat detection (i.e. UEBA or UBA), is experiencing a renaissance. Once primarily used to identify suspicious activity, it’s now being reimagined as a powerful post-detection technology that enhances incident response processes. By leveraging behavioral insights during alert triage and investigation, SOCs can transform their workflows to become more

The Kahneman-Treisman Center is pleased to announce its newest initiative: Behavioral Science Desk. We know Princeton scholar-researchers from a range of disciplines are interested in finding ways to have their work intersect not only the insights of behavioral science but also real-world settings. The world's first and largest non-profit behavioral science innovation lab, ideas42(Link is external), is partnering with SPIA to bring Princeton students and faculty closer to research and design in the field in our new BSci Desk. Senior leaders from ideas42 will be available to students and faculty on campus as well as virtually, by appointment. See more at https://behavioralpolicy.princeton.edu/news/bscidesk

Regardless of their home department or primary discipline, Student Affiliates of the Kahneman-Treisman Center are interested in investigating the way humans make decisions and how the systems, practices, and policies that govern how people move through the world can be designed with these inclinations in mind. Open to all undergraduates, graduate students, and postdoctoral fellows and researchers, the bi-weekly meetings feature speakers from Princeton and other academic institutions as well as industry and public-sector practitioners in applied behavioral science. Check behavioralpolicy.princeton.edu for details of each meeting.

Are you a clinician looking to master CBT for Perfectionism? Or, learn more about the CBT model of perfectionism below. CBT Model of Perfectionism Perfectionism is not the same thing as conscientiousness. For example, in a recent study of older adults, perfectionism was both associated with increased risk of mortality whereas conscientiousness was associated with […]

The post Cognitive Behavioral Therapy Model of Perfectionism appeared first on Dr Alice Boyes.

The core beliefs that cause the most common problems fall into the following 3 categories. These core beliefs commonly underlie depression and anxiety. Helpless Core Beliefs such as: “I’m incompetent” “I’m needy” “I’m weak” “I’m defective, I don’t measure up” “I’m a failure” Unlovable Core Beliefs such as: “I’m unlovable” “I’m different” “I’m bound to […]

The post How To Change Negative Core Beliefs: A Straightforward Guide to Cognitive Behavioral Therapy (CBT) appeared first on Dr Alice Boyes.

Corey M. Ziemba
Oct 16, 2024; 44:e0349242024-e0349242024
Systems/Circuits

The visual world is richly adorned with texture, which can serve to delineate important elements of natural scenes. In anesthetized macaque monkeys, selectivity for the statistical features of natural texture is weak in V1, but substantial in V2, suggesting that neuronal activity in V2 might directly support texture perception. To test this, we investigated the relation between single cell activity in macaque V1 and V2 and simultaneously measured behavioral judgments of texture. We generated stimuli along a continuum between naturalistic texture and phase-randomized noise and trained two macaque monkeys to judge whether a sample texture more closely resembled one or the other extreme. Analysis of responses revealed that individual V1 and V2 neurons carried much less information about texture naturalness than behavioral reports. However, the sensitivity of V2 neurons, especially those preferring naturalistic textures, was significantly closer to that of behavior compared with V1. The firing of both V1 and V2 neurons predicted perceptual choices in response to repeated presentations of the same ambiguous stimulus in one monkey, despite low individual neural sensitivity. However, neither population predicted choice in the second monkey. We conclude that neural responses supporting texture perception likely continue to develop downstream of V2. Further, combined with neural data recorded while the same two monkeys performed an orientation discrimination task, our results demonstrate that choice-correlated neural activity in early sensory cortex is unstable across observers and tasks, untethered from neuronal sensitivity, and therefore unlikely to directly reflect the formation of perceptual decisions.

Innovation Center, William Penn High School. – On Tuesday, Lt. Governor Hall-Long joined Patrick and Amy Kennedy and leaders in behavioral health from around Delaware for a round table discussion aimed at improving student mental health. Patrick Kennedy is one of the world’s leading voices on mental health and addiction. He is best known as the lead sponsor of the Mental Health Parity […]

NEW CASTLE (Feb. 21, 2022) – A Dover primary care office is expanding behavioral health services for LGBTQ individuals thanks to federal grant funding. A Peaceful Place Integrated Care is using the grant to support the addition of a certified drug and alcohol counselor, a licensed clinical social worker, and a peer navigator to help […]

NEW CASTLE – The Delaware Department of Health and Social Services’ Division of Substance Abuse and Mental Health (DSAMH) announces significant advancement in capabilities for the Delaware Treatment and Referral Network (DTRN) with the launch of DTRN360, a Behavioral Health Coordination platform. DTRN360 is designed to bridge the gaps experienced by providers in caring for […]

Register online at https://us06web.zoom.us/webinar/register/WN_5tCSTHX4QLmo1JoCQ3rozA Dover, DE – On Tuesday, April 26 at 1:00 p.m. the Delaware Department of Correction invites you to join its next “DOC Insider Series” webinar with a focus on Cognitive Behavioral Therapy.  The DOC Insider Series provides members of the public with an inside the walls look at Delaware’s correctional programs, practices, […]

NEW CASTLE (May 15, 2020) – The Delaware Division of Substance Abuse and Mental Health (DSAMH) has launched a phone line dedicated to helping Delawareans cope with stress and address behavioral health needs during the coronavirus pandemic. The Delaware Hope Line – 1 (833) 9-HOPEDE or (833) 946-7333 – is open 24 hours a day, […]

The state will name its 2024 Delaware Behavioral Health Professional of the Year at a statewide celebration on Monday. Delaware’s districts and the Delaware Charter School Network named local Behavioral Health Professionals of the Year for 2024. Following an application and interview process, one will be named the state honoree.

Shannon Gronau, a school counselor from the Milford School District, is the state’s 2024 Delaware Behavioral Health Professional of the Year.

There's no question that we're all increasingly, and often exclusively, interacting with brands digitally. Consumers are now online through countless mechanisms – from laptops and mobile apps to AI-enabled voice assistants and sensor-based wearables. Engagement is diversifying in fascinating new ways. And when organizations can't see their customers interacting in [...]

SAS Customer Intelligence 360: Behavioral event tracking, targeting & engagement analysis was published on Customer Intelligence Blog.

On September 2 (3pm UTC / 11am EDT), I'll be joining Jonathon Karelse, CEO of NorthFind Management, for an interactive "fireside chat" on the application of Behavioral Economics in demand planning. This is part of the Foresight Webinar Series, and registration is free. Since we first met at an Institute [...]

The post Behavioral economics in demand planning (webinar September 2) appeared first on The Business Forecasting Deal.

This study finds that investing in sanitation not only improved children’s health, but also created valuable time-savings for all household members.

Despite a significant decrease in the number of prescriptions for opioids, the opioid crisis continues, fueled in large part by the availability of the phenylpiperidine mu opioid receptor (MOR) agonist fentanyl. In contrast, the number of prescriptions for and the off-label use of gabapentinoids (gabapentin and pregabalin) has increased dramatically, with gabapentinoids commonly detected in opioid overdose victims. Although gabapentinoids can decrease the potency of the opioid receptor antagonist naloxone to reverse heroin-induced hypoventilation in male rats, the specificity and nature of interaction between gabapentinoids and MOR agonists and any potential sex difference in those interactions are not well characterized. Gabapentinoids were studied in female and male rats discriminating fentanyl (0.0032 mg/kg, i.p.) or cocaine (3.2 mg/kg, i.p.). Alone, neither gabapentin nor pregabalin significantly increased fentanyl- or cocaine-appropriate responding. In rats discriminating fentanyl, each gabapentinoid dose-dependently shifted the fentanyl and heroin discrimination dose-effect functions to the left, whereas naloxone dose-dependently shifted the fentanyl and heroin discrimination dose-effect functions to the right. Each gabapentinoid (100 mg/kg) significantly decreased the potency of naloxone to antagonize the discriminative stimulus effect of fentanyl or heroin. In contrast, each gabapentinoid dose-dependently shifted the cocaine and d-methamphetamine discrimination dose-effect functions to the right. There were no significant sex differences in this study. These results suggest that gabapentinoids impact the misuse of opioids, the co-use of opioids and stimulant drugs, and the increasing number of overdose deaths in individuals using opioids, stimulant drugs, and gabapentinoids in mixtures.