ici A pH-response-based fluorescent probe for detecting the mitophagy process by tracing changes in colocalization coefficients By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2241-2247DOI: 10.1039/D4AY00211C, PaperNongyi Hao, Zekun Jiang, Lina Zhou, Xiaoyu Dai, Xiuqi KongA novel pH-response fluorescent probe MP for the detection of mitophagy process via tracing colocalization coeffcients was developed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici The preparation of a boronate affinity-based controlled oriented imprinting coating on a silica nanoparticle surface for the separation and purification of shikimic acid in herbal medicine By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00219A, PaperYumin Yang, Daojin Li, Bingqian LiuShikimic acid (SA) is one of the most effective drugs against the A (H1N1) virus and has high medicinal value.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici Politicising the laddu: On the Tirupati laddu and its ‘adulteration’ By www.thehindu.com Published On :: Tue, 24 Sep 2024 00:30:00 +0530 The Tirupati laddu issue should be limited to one of quality control Full Article Editorial
ici Judge and prejudice: On conduct in judicial proceedings By www.thehindu.com Published On :: Fri, 27 Sep 2024 00:10:00 +0530 Judicial officers must be mindful of language that reveal bias Full Article Editorial
ici Regulation role: On the 2024 Medicine Nobel By www.thehindu.com Published On :: Tue, 08 Oct 2024 00:36:00 +0530 The discovery of microRNA changed the understanding of gene regulation Full Article Editorial
ici Complicit: On India and the U.S and Canada cases By www.thehindu.com Published On :: Mon, 21 Oct 2024 00:30:00 +0530 India must come clean on its stance on transnational killings Full Article Editorial
ici Beyond intoxication: On alcohol regulation, judicial verdict By www.thehindu.com Published On :: Mon, 28 Oct 2024 00:20:00 +0530 Batting for States, the Supreme Court of India holds federal balance on regulating alcohol Full Article Editorial
ici Pathogenesis of Alzheimer's disease and therapeutic strategies involving traditional Chinese medicine By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00660G, Review ArticleShutang Li, Jinfei YangAs research on AD has progressed, TCM and its active ingredients have increasingly played a crucial role in clinical treatment. This article summarizes extracts from TCM and briefly elucidates their pharmacological mechanisms against AD.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici Semisynthetic phytochemicals in cancer treatment: a medicinal chemistry perspective By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3345-3370DOI: 10.1039/D4MD00317A, Review ArticleMeghna Arora, Ankit Kumar Singh, Adarsh Kumar, Harshwardhan Singh, Prateek Pathak, Maria Grishina, Jagat Pal Yadav, Amita Verma, Pradeep KumarSemisynthetic phytochemicals in cancer treatment.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici A comprehensive apoptotic assessment of niloticin in cervical cancer cells: a tirucallane-type triterpenoid from Aphanamixis polystachya (Wall.) Parker By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3444-3459DOI: 10.1039/D4MD00318G, Research ArticleAnuja Gracy Joseph, Mohanan Biji, Vishnu Priya Murali, Daisy R. Sherin, Alisha Valsan, Vimalkumar P. Sukumaran, Kokkuvayil Vasu Radhakrishnan, Kaustabh Kumar MaitiNiloticin, a triterpenoid from Aphanamixis polystachya, induces apoptosis in HeLa cells which is primarily validated through in silico analysis and subsequently in vitro apoptotic evaluation by modulating the apoptotic proteins.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici Exploring 7β-amino-6-nitrocholestens as COVID-19 antivirals: in silico, synthesis, evaluation, and integration of artificial intelligence (AI) in drug design: assessing the cytotoxicity and antioxidant activity of 3β-acetoxynitrocholestane By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00257A, Research Article Shahabuddin, Uzma, Mohammad Azam, Mehtab Parveen, Nurul Huda Abd Kadir, Kim Min, Mahboob AlamIn light of the ongoing pandemic caused by SARS-CoV-2, effective and clinically translatable treatments are desperately needed for COVID-19 and its emerging variants.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici Introduction to the themed collection on ‘AI in Medicinal Chemistry’ By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3284-3285DOI: 10.1039/D4MD90035A, EditorialJian Zhang, Ola Engkvist, Gerhard HesslerJian Zhang, Ola Engkvist and Gerhard Hessler introduce the RSC Medicinal Chemistry themed collection on ‘AI in Medicinal Chemistry’.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici Recent advances from computer-aided drug design to artificial intelligence drug design By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00522H, Review ArticleKeran Wang, Yanwen Huang, Yan Wang, Qidong You, Lei WangCADD and AIDD contribute to the drug discovery.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici Medicinal chemistry-based perspective on thiophene and its derivatives: Exploring the structural insights to discover plausible druggable leads By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00450G, Review ArticleShikha Thakur, Devendra Kumar, shivani jaiswal, Kapil Kumar Goel, Pramod Rawat, Vivek Srivastava, Sonia Dhiman, Hemant R Jadhav, Ashish Ranjan DwivediThiophene is a privileged pharmacophore in medicinal chemistry owing to its diversified biological attributes. The thiophene moiety has been ranked 4th in US FDA drug approval of small drug molecules,...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici A decade of pyridine-containing heterocycles in US FDA approved drugs: a medicinal chemistry-based analysis By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00632A, Review ArticleAshish Ranjan Dwivedi, Shivani Jaiswal, Deepak Kukkar, Roshan Kumar, Thakur Gurjeet Singh, Mahendra Pratap Singh, Abhay M. Gaidhane, Sorabh Lakhanpal, K. Nagendra Prasad, Bhupinder KumarThe present review is a concerted effort to cover drugs bearing pyridine rings approved in the last decade, and it provides thorough discussion and commentary on their pharmacokinetics and pharmacodynamics together with in-depth structural analysis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici meso-Substituted AB3-type phenothiazinyl porphyrins and their indium and zinc complexes photosensitising properties, cytotoxicity and phototoxicity on ovarian cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00601A, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Brém Balázs, Bianca Stoean (Vasile), Éva Molnár, Eva Fischer-Fodor, Ovidiu Bălăcescu, Raluca Borlan, Monica Focsan, Adriana Grozav, Patriciu Achimaş-Cadariu, Emese Gál, Luiza GainaNew meso-substituted AB3-type phenothiazinyl porphyrins and ferrocenylvinyl phenothiazinyl porphyrin were synthesised by Suzuki–Miyaura and Mizoroki–Heck cross-coupling reactions, respectively.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici Light enhanced cytotoxicity and antitumoral effect of a ruthenium-based photosensitizer inspired from natural alkaloids By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00600C, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Gennaro Sanità, Maria Laura Alfieri, Barbara Carrese, Serena Damian, Vincenza Mele, Gaetano Calì, Brigida Silvestri, Sebastiano Marra, Susan Mohammadi, Giuseppina Luciani, Paola Manini, Annalisa LambertiBiological assays carried out on melanoma and breast cancer cells highlighted the role of light in boosting the cytotoxic effect of a ruthenium complex featuring a dihydroisoquinoline ligand suggesting applications in photodynamic therapy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici SIGMAP: an explainable artificial intelligence tool for SIGMA-1 receptor affinity Prediction By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00722K, Research Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Maria Cristina Lomuscio, Nicola Corriero, Vittoria Nanna, Antonio Piccinno, Michele Saviano, Rosa Lanzilotti, Carmen Abate, Domenico Alberga, Giuseppe Felice MangiatordiDeveloping sigma-1 receptor (S1R) modulators is considered a valuable therapeutic strategy to counteract neurodegeneration, cancer progression, and viral infections, including COVID-19. In this context, in-silico tools capable of accurately predicting...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici Agro-tourism push needs industry-specific policies, say farmers By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:37:41 +0530 Full Article Tiruchirapalli
ici Students and agriculture officials grapple with logistical, technical issues during digital crop survey By www.thehindu.com Published On :: Sat, 09 Nov 2024 20:32:48 +0530 Full Article Tiruchirapalli
ici 582: Lifetime Plan, Pricing #HotDrama, and CSS Resets By shoptalkshow.com Published On :: Mon, 11 Sep 2023 09:33:44 +0000 Getting tripped up on audio at conferences, announcing the ShopTalk Show Lifetime Plan, some Once pricing #hotdrama, remembering Molly Holzschlag, web components, Luro launch day thoughts, and a question about using a normalize or sanitize in 2023 prompts a run through of Andy Bell's Modern CSS Reset. Full Article All Episodes CSS CSS Resets Pricing
ici Green power, officially By www.thehindu.com Published On :: Fri, 18 Mar 2016 15:31:36 +0530 The cumulative effects of changing the way government builds can have a lasting impact on the country’s carbon footprint Full Article Property Plus
ici Making medicines at the point of patient care By www.thehindubusinessline.com Published On :: Sun, 03 Nov 2024 18:52:12 +0530 UK readies law allowing preparation of medicines near hospital setting to reach patients safely, quickly Full Article Pulse
ici AAP MLA ‘assaults’ MCD official, case registered By www.thehindu.com Published On :: Thu, 07 Nov 2024 01:10:03 +0530 Full Article Delhi
ici India's climate policies expected to reduce CO2 emissions by around 4 billion tonnes by 2030: Report By www.thehindu.com Published On :: Thu, 07 Nov 2024 18:34:50 +0530 The study by Delhi-based independent think tank Council on Energy, Environment and Water (CEEW) said policies for India's power, residential and transport sectors have already saved 440 million tonnes of carbon dioxide (MtCO2) between 2015 and 2020. Full Article Environment
ici Leaves taken by doctors during RG Kar protest to be adjusted against their official quota: AIIMS Delhi By www.thehindu.com Published On :: Fri, 08 Nov 2024 01:12:12 +0530 Full Article Delhi
ici Dialectics of government deficits By www.thehindubusinessline.com Published On :: Sun, 03 Jan 2021 20:03:22 +0530 The book, espousing modern monetary theory, busts a few conservative myths on government spending Full Article Books
ici International conference to recommend policies to address gender inequality at farms By www.thehindu.com Published On :: Sat, 07 Oct 2023 03:43:00 +0530 “The conference aims to promote the sharing of cutting-edge knowledge on gender and inclusion in agri-food systems.” Full Article India
ici Open sale of hazardous pesticides continues to impact the health of farmers in Maharashtra By www.thehindu.com Published On :: Sat, 23 Dec 2023 21:26:27 +0530 In 2017, reports of pesticide poisoning emerging from Maharashtra drew global criticism against India’s pesticide regulation policies, yet not much appears to have changed since then Full Article India
ici SC notice to Centre on plea alleging overuse of pesticides on crops and food items By www.thehindu.com Published On :: Sat, 18 May 2024 16:51:00 +0530 Full Article India
ici Home cooks in Thiruvananthapuram are championing artificial additive-free jams, preserves, juice, ethnic eats and more By www.thehindu.com Published On :: Wed, 16 Oct 2024 13:42:08 +0530 Four home cooks in Thiruvananthapuram are turning fruits into value-added products without using artificial flavours or preservatives Full Article Features
ici Markets rebound in early trade on buying in ICICI bank, firm trends in Asian peers By www.thehindu.com Published On :: Mon, 28 Oct 2024 10:39:29 +0530 Equity markets rise on ICICI bank boost, Asian trends, and domestic buying and also BSE Sensex, NSE Nifty climb Full Article Markets
ici Agriculture officials conduct surprise checks at fertiliser outlets in Tiruchi district By www.thehindu.com Published On :: Sun, 10 Nov 2024 21:09:17 +0530 63 outlets were checked across various agricultural blocks for illegal hoarding and also to check adherence to maximum retail price; dealers asked to comply with guidelines Full Article Tiruchirapalli
ici Network interactions simultaneously enhance stiffness and lubricity of triple-network hydrogels By pubs.rsc.org Published On :: Soft Matter, 2024, Advance ArticleDOI: 10.1039/D4SM00969J, PaperNabila Ali, Connor J. Demott, Olivia F. Dingus, Melissa A. Grunlan, Alison C. DunnTough hydrogels with a charge-variable third network were assessed for biomimicking lubricity in both water and FBS solution.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici Effective patchiness from critical points of a coarse-grained protein model with explicit shape and charge anisotropy By pubs.rsc.org Published On :: Soft Matter, 2024, 20,8455-8467DOI: 10.1039/D4SM00867G, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jens Weimar, Frank Hirschmann, Martin OettelCritical points of an anisotropic, coarse-grained protein model are used to detemine an “effective patchiness” by comparison to the Kern–Frenkel patchy model.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici Enhanced chemotaxis efficiency of Escherichia coli in viscoelastic solutions By pubs.rsc.org Published On :: Soft Matter, 2024, 20,8675-8683DOI: 10.1039/D4SM01094A, PaperShaoying Zhu, Rui He, Caijuan Yue, Rongjing Zhang, Junhua YuanE. coli shows enhanced chemotaxis in viscoelastic media, with faster migration and higher accumulation in attractant-rich areas compared to Newtonian conditions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici Interfacial viscoelasticity in oscillating drops of cyclodextrin-surfactant aqueous solution: experiments and theory By pubs.rsc.org Published On :: Soft Matter, 2024, Accepted ManuscriptDOI: 10.1039/D4SM01007H, PaperJosé Roberto Romero-Arias, Alberto S. Luviano, Miguel Costas, Aurora Hernandez-Machado, Rafael A BarrioWe present experiments involving oscillating droplets in aqueous cyclodextrin-surfactant solutions. In these experiments, α-cyclodextrin (αCD) and anionic surfactants exhibit remarkable viscoelasticity at the liquid/air interface, with dilatational modulus varying across...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ici ICICI Bank Q2 PAT rises 15% to ₹11,746 crore on strong core income growth By www.thehindubusinessline.com Published On :: Sat, 26 Oct 2024 18:54:10 +0530 NIM moderated 9 basis points sequentially to 4.27 per cent on higher cost of funds Full Article Money & Banking
ici ICICI Prudential Multi asset completes 22 years By www.thehindubusinessline.com Published On :: Mon, 11 Nov 2024 14:51:39 +0530 A lump sum investment of ₹10 lakh at the time of inception in October 31, 2002 will be worth about ₹7.26 crore given compounded annual growth rate of 22 per cent Full Article Money & Banking
ici Alone in the Abyss / directed by: Claudie Ottawa ; produced by: Manon Barbeau, Patricia Bergeron, Manon Barbeau, Yves Bisaillon, Ravida Din ; production agencies: Corporation Wapikoni mobile (Montreal), National Film Board of Canada (Montreal) By darius.uleth.ca Published On :: Montreal : National Film Board of Canada, 2018 Full Article
ici At Home : The Wound Inside / directed by: Darryl Nepinak ; produced by: Brendon Sawatzky, Alicia Smith, David Christensen ; production agency: National Film Board of Canada (Montreal) By darius.uleth.ca Published On :: Montreal : National Film Board of Canada, 2012 Full Article
ici Governor participates in Uttarakhand Foundation Day celebrations at Raj Bhavan By www.thehindu.com Published On :: Sat, 09 Nov 2024 18:17:26 +0530 Full Article Andhra Pradesh
ici Nandyal collector asks officials to complete land acquisition By www.thehindu.com Published On :: Mon, 11 Nov 2024 18:30:01 +0530 Full Article Andhra Pradesh
ici Endowments Secretary and Commissioner takes oath as ex-officio member of TTD Trust Board By www.thehindu.com Published On :: Mon, 11 Nov 2024 18:58:44 +0530 Full Article Andhra Pradesh
ici YSRCP social media activist Varra Ravindra Reddy sent to judicial remand By www.thehindu.com Published On :: Tue, 12 Nov 2024 20:08:23 +0530 Police form district-level teams to monitor ‘defamatory posts’ Full Article Andhra Pradesh
ici Stop digging borewells for uranium, A.P. Chief Minister directs officials By www.thehindu.com Published On :: Tue, 12 Nov 2024 21:05:53 +0530 Full Article Andhra Pradesh
ici Vorticity, statistical mechanics, and Monte Carlo simulation [electronic resource] / Chjan Lim, Joseph Nebus By darius.uleth.ca Published On :: New York : Springer, 2007 Full Article
ici Address problems in accident black spots scientifically, Udupi DC tells officials By www.thehindu.com Published On :: Tue, 29 Oct 2024 20:04:27 +0530 Full Article Mangaluru
ici Poojary asks officials to hasten Karavali junction-Malpe stretch highway widening project by paying compensation to land losers by November 10 By www.thehindu.com Published On :: Thu, 31 Oct 2024 07:00:00 +0530 Full Article Mangaluru
ici Don’t delay loan sanction and disbursal to central schemes beneficiaries, Srinivas Poojary tells banks By www.thehindu.com Published On :: Thu, 07 Nov 2024 07:00:00 +0530 Full Article Mangaluru
