It is increasingly being realised that achieving net-zero is not possible without nuclear energy

Karnataka has achieved 10.2% GDP in 2023-24, higher to national average of 8.2%, says Udupi district in-charge minister

He demanded Telangana government to immediately release reimbursement and scholarship dues amount to about ₹4,000 crore

Paatal Lok is definitely a must watch show.The credit for its success goes to the writers who enthralled us with their unique characters, but also to the wonderful band of actors who grabbed the opportunity to showcase their frightening raw talent, notes Aseem Chhabra.

'Top actors came to me while Kabali was being shot, to ask me to cast them in at least one scene with Thalaivar -- even if it required them to clean a table on the side while Thalaivar is in the shot.' Kabali producer Kalaipuli S Thanu tries to explain the Rajinikanth phenomenon.

Rajinikanth gave a realistic portrayal in his 2016 release Kabali.

U.S. intelligence officials say a video that purports to show election fraud in Georgia is fake and the work of “Russian influence actors."

A host of macroeconomic data announcements, the last batch of September quarter earnings, global trends, and trading activity of foreign investors will be the major driving factors for the equity market this week, according to analysts. Equity markets would remain closed on Friday for Guru Nanak Jayanti. "India is set to release CPI and IIP data on November 12, with WPI data expected on November 14.

Thalassemia is a group of inherited blood disorders that has a similar characteristic: defective and reduced production of haemoglobin, the iron-containing protein in red blood cells that helps in carrying oxygen throughout the body. Beta-thalassemia (BT) is one of

Growing a beard has now become a fashion amongst youngsters. Nowadays, a majority of girls love to see their partners with a beard. Cinema is the main reason for making this beard look famous amongst the masses. South Industries

After opening nearly 3 per cent higher, RIL share price slipped 1.90 per cent in Mondays' trade. American private equity firm Silver Lake Partner announced an investment of Rs 5,655.75 crore in Reliance Jio.

The rally in Sensex and Nifty was supported by buying in financial counters with HDFC Bank, HDFC, ICICI Bank and Bajaj Finance as top index contributors

With theatres being shut since for over a month now, many small and mid-rung production houses are understood to be in talks with video over-the-top (OTT) platforms for direct-to-digital launch of their unreleased movies.

Whatever a company’s size, one of the constant challenges it faces is to achieve optimum productivity from its workforce. There are several particularly important factors […]

The post 5 factors with an impact on labor productivity appeared first on e-Learning Feeds.

After an extended period of lockdown, economic stimulus is badly needed.

This paper presents the findings of an international stocktaking of the regulatory frameworks that apply to institutional investment in different jurisdictions and how these frameworks are interpreted by institutional investors in terms of their ability or responsibility to integrate environmental, social and governance (ESG) factors in their governance processes.

This paper presents the findings of an international stocktaking of the regulatory frameworks that apply to institutional investment in different jurisdictions and how these frameworks are interpreted by institutional investors in terms of their ability or responsibility to integrate environmental, social and governance (ESG) factors in their governance processes.

When it comes to labour and migration, global governance of almost any kind is missing. When it comes to labour, the International Labour Organization, which is the oldest among the institutions mentioned here, has little power and deals mostly with national labour rules.

This report investigates the effects of select climate policies, non-climate policies, as well as political economy factors on the decarbonisation of electricity in OECD countries from 2000 to 2015. Effects are analysed on the three phases of decarbonisation: (1) increasing the share of renewables installed, (2) increasing the use of renewables in generation, and (3) reducing the emissions from electricity.

When it comes to labour and migration, global governance of almost any kind is missing. When it comes to labour, the International Labour Organization, which is the oldest among the institutions mentioned here, has little power and deals mostly with national labour rules.

The higher the level of education, the higher the salary cost of teachers per student. In Belgium (Flemish Community), France and Spain, the difference in the annual salary cost between the primary and upper secondary levels of education exceeds USD 1 800 in 2010.

The star, 55, was sending a personalised message to a fan at £249 a pop. In one clip, he says in reference to his films: 'I hope you enjoy me bashing the s**t out of some of them prima donna actors. I do love it.'

On Monday, banks and NBFCs (non-banking finance companies) were among the biggest losers on the Indian stock exchanges. ICICI Bank ended 10.56 percent lower, HDFC 9.98 percent down, HDFC Bank 7.89 percent lower, SBI was down 5.88 percent and NSE's banking

Shivin Narang, Vijayendra Kumeria and Meera Deosthale among others have shared loving notes on the occasion of Mother's Day 2020.

Dedicating a whole day to honour and celebrate the women who raised us is beyond special. Mothers are selfless, they are strong and can overcome any obstacle with all their might to protect their family. With Mother's Day just round the

Vinay Rajkumar recently unveiled the teaser and posters of his upcoming movies (Gramayana and 10) as birthday gifts to his fans. The actor who turned 31-years-old on May 7, also opened up about the life under lockdown in a recent interview

Chagas diseases (CD) is a silent yet life-threatening disease caused by a protozoan parasite named Trypanosoma cruzi (T.cruzi). The disease is also known as American trypanosomiasis as it is found mainly in rural areas of America where there is a lack

Thyroid cancer is the cancer of the thyroid gland which is found at the neck's front just below Adam's apple. The thyroid gland is a butterfly-shaped gland with two lobes, one at each side joined by a narrow tissue called the

Thalassemia is a group of inherited blood disorders that has a similar characteristic: defective and reduced production of haemoglobin, the iron-containing protein in red blood cells that helps in carrying oxygen throughout the body. Beta-thalassemia (BT) is one of

The actress came in support of the artists who were backlashed for their 'intolerance' comment.

TIRUVARUR Power tillers and tractors purchased by the Farmers Producers Organisations in Tiruvarur district for deployment in the forthcoming crop sea

Parking usage down, contractors seek fee relief

The bond-valence method was performed on 51 crystal data sets from nitrogenase proteins, indicating the presence of molybdenum(III) in FeMo cofactors and vanadium(III) with more reduced iron complements in FeV cofactors.

Good prior estimates of the effective root-mean-square deviation (r.m.s.d.) between the atomic coordinates of the model and the target optimize the signal in molecular replacement, thereby increasing the success rate in difficult cases. Previous studies using protein structures solved by X-ray crystallography as models showed that optimal error estimates (refined after structure solution) were correlated with the sequence identity between the model and target, and with the number of residues in the model. Here, this work has been extended to find additional correlations between parameters of the model and the target and hence improved prior estimates of the coordinate error. Using a graph database, a curated set of 6030 molecular-replacement calculations using models that had been solved by X-ray crystallography was analysed to consider about 120 model and target parameters. Improved estimates were achieved by replacing the sequence identity with the Gonnet score for sequence similarity, as well as by considering the resolution of the target structure and the MolProbity score of the model. This approach was extended by analysing 12 610 additional molecular-replacement calculations where the model was determined by NMR. The median r.m.s.d. between pairs of models in an ensemble was found to be correlated with the estimated r.m.s.d. to the target. For models solved by NMR, the overall coordinate error estimates were larger than for structures determined by X-ray crystallography, and were more highly correlated with the number of residues.

Most articles dealing with R2TSi3 compounds are only interested in one specific composite or in a series of composites with varying T elements while keeping R fixed (or vice versa). The present work gives an overview of the complete range of 2:1:3 silicides, similar those of Hoffmann & Pöttgen (2001) and Pan et al. (2013). In contrast to the work of Hoffmann & Pöttgen (2001), reasons for formation of the different symmetries and superstructures are discussed. Here, crystallographic properties are in[the] focus, whereas physical and magnetic properties are omitted because those are given by Pan et al. (2013). READS LIKE AN ABSTRACT, please re-write and remove references if possible. Should be two sentences max.

National Zoo lion keeper Rebecca Stites, at right in photo, was joined by Georgie Henley, at left in photo, and Skandar Keynes, actors in the […]

The post Zoo lion cub named “Aslan” by actors Georgie Henley and Skandar Keynes appeared first on Smithsonian Insider.

The bond-valence method has been used for valence calculations of FeMo/V cofactors in FeMo/V proteins using 51 crystallographic data sets of FeMo/V proteins from the Protein Data Bank. The calculations show molybdenum(III) to be present in MoFe7S9C(Cys)(HHis)[R-(H)homocit] (where H4homocit is homocitric acid, HCys is cysteine and HHis is histidine) in FeMo cofactors, while vanadium(III) with a more reduced iron complement is obtained for FeV cofactors. Using an error analysis of the calculated valences, it was found that in FeMo cofactors Fe1, Fe6 and Fe7 can be unambiguously assigned as iron(III), while Fe2, Fe3, Fe4 and Fe5 show different degrees of mixed valences for the individual Fe atoms. For the FeV cofactors in PDB entry 5n6y, Fe4, Fe5 and Fe6 correspond to iron(II), iron(II) and iron(III), respectively, while Fe1, Fe2, Fe3 and Fe7 exhibit strongly mixed valences. Special situations such as CO-bound and selenium-substituted FeMo cofactors and O(N)H-bridged FeV cofactors are also discussed and suggest rearrangement of the electron configuration on the substitution of the bridging S atoms.

Su Ming Sun, Amandine Batte, Mireille Tittel-Elmer, Sophie van der Horst, Tibor van Welsem, Gordon Bean, Trey Ideker, Fred van Leeuwen, and Haico van Attikum

Eukaryotic chromosomes are replicated in interphase and the two newly duplicated sister chromatids are held together by the cohesin complex and several cohesin auxiliary factors. Sister chromatid cohesion is essential for accurate chromosome segregation during mitosis, yet has also been implicated in other processes, including DNA damage repair, transcription and DNA replication. To assess how cohesin and associated factors functionally interconnect and coordinate with other cellular processes, we systematically mapped genetic interactions of 17 cohesin genes centered on quantitative growth measurements of >52,000 gene pairs in budding yeast. Integration of synthetic genetic interactions unveiled a cohesin functional map that constitutes 373 genetic interactions, revealing novel functional connections with post-replication repair, microtubule organization and protein folding. Accordingly, we show that the microtubule-associated protein Irc15 and the prefoldin complex members Gim3, Gim4 and Yke2 are new factors involved in sister chromatid cohesion. Our genetic interaction map thus provides a unique resource for further identification and functional interrogation of cohesin proteins. Since mutations in cohesin proteins have been associated with cohesinopathies and cancer, it may also identify cohesin interactions relevant in disease etiology.

Structural investigations of amorphous and nanocrystalline phases forming in solution are historically challenging. Few methods are capable of in situ atomic structural analysis and rigorous control of the system. A mixed-flow reactor (MFR) is used for total X-ray scattering experiments to examine the short- and long-range structure of phases in situ with pair distribution function (PDF) analysis. The adaptable experimental setup enables data collection for a range of different system chemistries, initial supersaturations and residence times. The age of the sample during analysis is controlled by adjusting the flow rate. Faster rates allow for younger samples to be examined, but if flow is too fast not enough data are acquired to average out excess signal noise. Slower flow rates form older samples, but at very slow speeds particles settle and block flow, clogging the system. Proper background collection and subtraction is critical for data optimization. Overall, this MFR method is an ideal scheme for analyzing the in situ structures of phases that form during crystal growth in solution. As a proof of concept, high-resolution total X-ray scattering data of amorphous and crystalline calcium phosphates and amorphous calcium carbonate were collected for PDF analysis.

Relativistic electron diffraction depends on linear and quadratic terms in the electric potential, the latter being neglected in the frequently used relativistically corrected Schrödinger equation. The quadratic electric potential term modifies atomic scattering amplitudes in particular for large-angle scattering and backscattering. The respective correction increases with increasing scattering angle, increasing atomic number and increasing kinetic energy. Conventional tabulations for electron scattering and its large-angle extrapolations can be amended in closed form by a universal correction based on the screened Coulomb potential squared.

A new aspherical scattering factor formalism has been implemented in the crystallographic least-squares refinement program SHELXL. The formalism relies on Gaussian functions and can optionally complement the independent atom model to take into account the deformation of electron-density distribution due to chemical bonding and lone pairs. Asphericity contributions were derived from the electron density obtained from quantum-chemical density functional theory computations of suitable model compounds that contain particular chemical environments, as defined by the invariom formalism. Thanks to a new algorithm, invariom assignment for refinement in SHELXL is automated. A suitable parameterization for each chemical environment within the new model was achieved by metaheuristics. Figures of merit, precision and accuracy of crystallographic least-squares refinements improve significantly upon using the new model.

Su Ming Sun
Apr 16, 2020; 0:jcs.237628v1-jcs.237628
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