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MdMYB6 regulates anthocyanin formation in apple both through direct inhibition of the biosynthesis pathway and through substrate removal




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Author Correction: Quantum metasurfaces with atom arrays




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A stereotyped light chain may shape virus-specific B-cell receptors in HCV-dependent lymphoproliferative disorders




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Opioid and Hedgehog signalling pathways converge to modulate OA




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<i>KRAS</i> amplification in metastatic colon cancer is associated with a history of inflammatory bowel disease and may confer resistance to anti-EGFR therapy




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Deconvoluting MLL1-dependent pathways in hematopoiesis and leukemogenesis




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Abstracts from the 2nd International Norges Teknisk-Naturvitenskapelige Universitet (NTNU) Symposium: Day 1—Immunotherapy and Hematology




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Team Players

Microbial partnerships turn out to be more common and influential than scientists could have ever imagined




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Galileo’s story is always relevant




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Picking away at fossilized skeletons




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Tunable correlated states and spin-polarized phases in twisted bilayer–bilayer graphene




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Multilayered mechanisms ensure that short chromosomes recombine in meiosis




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A better way to ‘squeeze the vacuum’ could speed the search for gravitational waves




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Isolation of SARS-CoV-2-related coronavirus from Malayan pangolins




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Cellular thermal shift assay for the identification of drug–target interactions in the <i>Plasmodium falciparum</i> proteome




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Short-term NAD<sup>+</sup> supplementation prevents hearing loss in mouse models of Cockayne syndrome




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Repository of proposed pathways and protein–protein interaction networks in age-related macular degeneration




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Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells




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Author Correction: Quantum wave–particle superposition in a delayed-choice experiment




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An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9




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Anger and shock may follow tooth loss




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Noncanonical amino acids on display




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COVID-19 Research in Brief: 2 May to 8 May, 2020




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Defense Playbook for Campaigns

The 2018 National Defense Strategy (NDS) is predicated on a single organizing principle: America’s military pre-eminence is rapidly eroding. This is not a new concept. For years, experts have warned that the economic and technological advancements of U.S. adversaries, coupled with the 2008 financial crisis and America’s focus on peripheral conflicts, have caused a decline in America’s military dominance. 

In this context, the advances of near-peer competitors such as China and Russia have created plausible “theories of victory” in potential conflicts across Eastern Europe and East Asia. Competitors’ unaddressed improvements in strategic innovation, economic investment, and dual-use technology increases the risk of conflict and strains the U.S. alliance system. It is urgent that the United States reestablish and maintain credible deterrents against these near-peer competitors. After decades of focusing on post-Cold War ‘shaping’ operations, the American military needs to reinvigorate for full spectrum great power competition.

This report is intended as a blueprint on how to begin that process from graduate students at the Belfer Center for Science and International Affairs at Harvard University. Contained inside are 12 memorandums. Each provides a high-level overview and specific recommendations on a key issue of American defense policy. 




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How the Pentagon Is Struggling to Stay out of Politics

 Gen. Mark. A. Milley’s job is to provide sound military advice to the president. But at a deeper level, his responsibility is to safeguard the independence and integrity of the armed forces. The last thing the country needs is a military leadership that’s trying to curry favor with any commander in chief, particularly one who’s hungry for affirmation.




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Maxwell Taylor's Cold War: From Berlin to Vietnam

Nathaniel Moir reviews Maxwell Taylor's Cold War: From Berlin to Vietnam by Ingo Trauschweizer.




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H-Diplo Review Essay 192 on Lawson. Anatomies of Revolution

Emily Whalen reviews Anatomies of Revolution by George Lawson (Cambridge: Cambridge University Press, 2019).




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COVID-19 Pandemic Accelerates the Rise of Digital Payments

Could using the cash in your pocket have the potential to spread covid-19? That question has rarely appeared in the news, but many governments and leaders in the digital payments industry are wondering how the virus might impact the use of cash. Several countries have already taken drastic measures to limit circulation of bank notes. Could such interventions lead to the end of cash payments?




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Carmen Reinhart Says Argentina’s Debt Workout Won’t Be Its Last

Argentina’s latest effort to restructure its overseas debt probably won’t be its last, according to Harvard University economist Carmen Reinhart, who has sounded alarms over coming emerging markets crises in Venezuela and Turkey.




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H-Diplo Review Essay 192 on Lawson. Anatomies of Revolution

Emily Whalen reviews Anatomies of Revolution by George Lawson (Cambridge: Cambridge University Press, 2019).




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COVID-19 Pandemic Accelerates the Rise of Digital Payments

Could using the cash in your pocket have the potential to spread covid-19? That question has rarely appeared in the news, but many governments and leaders in the digital payments industry are wondering how the virus might impact the use of cash. Several countries have already taken drastic measures to limit circulation of bank notes. Could such interventions lead to the end of cash payments?




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Carmen Reinhart Says Argentina’s Debt Workout Won’t Be Its Last

Argentina’s latest effort to restructure its overseas debt probably won’t be its last, according to Harvard University economist Carmen Reinhart, who has sounded alarms over coming emerging markets crises in Venezuela and Turkey.




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Correction to ‘Genotyping of Malaysian G6PD-deficient neonates by reverse dot blot flow-through hybridisation’




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Maxwell Taylor's Cold War: From Berlin to Vietnam

Nathaniel Moir reviews Maxwell Taylor's Cold War: From Berlin to Vietnam by Ingo Trauschweizer.




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Washington Should Take Action on AI or Stay Out of the Way

Federal and local regulations are part of the solution to tough issues related to Artificial Intelligence, writes K. Gretchen Greene, but no regulatory approach on its own can fully answer these questions today. "Finding answers will require significant investments in research and development, collaboration, negotiation, and experimentation, deep and careful thought across many fields and leadership at all levels, across and between governments. The U.S. federal government is well positioned to lead, but if it won't, it should at least stay out of the way."




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Harvard Business School Professor Rebecca Henderson Outlines Ways Organizations are Changing in Response to the Coronavirus Pandemic and Climate Change in New Edition of "Environmental Insights"

Rebecca Henderson, the John and Natty McArthur University Professor at Harvard University, shared her perspectives on how large organizations are changing in response to the coronavirus pandemic and climate change in the newest episode of "Environmental Insights: Discussions on Policy and Practice from the Harvard Environmental Economics Program," a podcast produced by the Harvard Environmental Economics Program. Listen to the interview here. Listen to the interview here.




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Associations between the activity of placental nutrient-sensing pathways and neonatal and postnatal metabolic health: the ECHO Healthy Start cohort