While the island and world are facing unprecedented challenges due to the Covid-19 pandemic, one thing remains constant: the island’s beauty. As always, Bernews features a “Photo of the Day” in our email newsletters and various social media accounts seven days a week in order to continue to highlight the stunning scenes that Bermuda has to offer. Always popular, […] (Click to read the full article)

Bernews posted more than 1,000 videos on YouTube during 2019, with the top twenty most viewed videos on our channel including coverage of Cup Match, the Rising Inferno Concert with Koffee, the Bermuda Carnival Parade of Bands, the island’s LGBTQ Pride Parade, the Bermuda Day Parade, coverage of Hurricane Humberto, an overview of the NCL […] (Click to read the full article)

Shiona Turini recently worked as a stylist for The New York Times’ T Magazine, with the Bermudian fashion consultant styling a group which included a number of highly prominent black actresses and entertainers including Halle Berry, Taraji Henson, Mary J. Blige, Angela Bassett, Lynn Whitfield, Kimberly Elise, and Viola Davis. Sharing one of the shoot’s photos […] (Click to read the full article)

Legal & General Reinsurance [L&G Re] has launched the Lighthouse Connect fund at the Bermuda Community Foundation, in partnership with the Mirrors Programme, to raise funds to provide free laptops to Bermuda public school students. A spokesperson said, “Bermuda-based Legal & General Reinsurance [L&G Re] has launched the Lighthouse Connect fund at the Bermuda Community […] (Click to read the full article)

Bermudian actor Nicholas Christopher is getting set to join the cast of a production of Band Geeks in Concert. The show, which will also star Ben Platt, Lindsay Mendez, and Patti Murin, will take place at Broadway supper club 54 Below today [Jan 18]. BroadwayWorld.com says, “Band Geeks features music by Mark Allen, Gaby Alter, […] (Click to read the full article)

Bernews posted more than 800 videos on YouTube during 2017, and the top twenty most viewed on our Youtube channel are actually all from the America’s Cup, which dominated our Youtube statistics, with the sailing event attaining over two million views on our Youtube channel alone. We have also compiled the top 20 ‘non America’s […] (Click to read the full article)

[Updated with video] “Bermuda has seen 5 shootings in the past two weeks,” Police Commissioner Stephen Corbishley said, adding that to “fully tackle gang violence requires the absolute support of communities.” Commissioner Corbishley said, “Bermuda has seen 5 shootings in the past two weeks. This has overshadowed the previous year where for the first time for […] (Click to read the full article)

One of the most fascinating things about planet Earth is the way that life shapes the Earth and the Earth shapes life. We only have to look back to the Great Oxygenation Event (GOE) of 2.4 billion years ago to see how lifeforms have shaped the Earth. In that event, phytoplanktons called cyanobacteria pumped the …

Continue reading "New Data Show How Phytoplankton Pumps Carbon Out of the Atmosphere at an Enormous Scale"

The post New Data Show How Phytoplankton Pumps Carbon Out of the Atmosphere at an Enormous Scale appeared first on Universe Today.

Every adult leader must complete an extensive Youth Protection Training program. ...

I hold these truths to be self-evident: Any law whatsoever, no matter how desirable on balance, will impose some costs on someone somewhere. In any society with more than about 12 people, it is virtually certain that those costs will be borne unequally. If the costs are borne unequally, then the costs borne by various […]

[I am happy to turn this space over to my former colleague and (I trust) lifelong friend Romans Pancs, who offers what he describes as a polemical essay. It has no references and no confidence intervals. It has question marks. It makes a narrow point and does not weigh pros and cons. It is an […]

You may recall in the early days of the pandemic, that pharma giant Gilead Sciences -- which has been accused of price gouging and (just last year!) charging exorbitant prices on drug breakthroughs developed with US taxpayer funds -- was able to sneak through an orphan works designation for its drug remdesevir for COVID-19 treatment. As we pointed out, everything about this was insane, given that orphan works designations, which give extra monopoly rights to the holders (beyond patent exclusivity), are meant for diseases that don't impact a large population. Gilead used a loophole: since the ceiling for infected people to qualify for orphan drug status is 200,000, Gilead got in its application bright and early, before there were 200,000 confirmed cases (we currently have over 1.3 million). After the story went, er... viral, Gilead agreed to drop the orphan status, realizing the bad publicity it was receiving.

After a brief dalliance with chloroquine, remdesivir has suddenly been back in demand as the new hotness of possible COVID-19 treatments. Still, a close reading of the research might give one pause. There have been multiple conflicting studies, and Gilead's own messaging has been a mess.

On April 23, 2020, news of the study’s failure began to circulate. It seems that the World Health Organization (WHO) had posted a draft report about the trial on their clinical trials database, which indicated that the scientists terminated the study prematurely due to high levels of adverse side effects.

The WHO withdrew the report, and the researchers published their results in The Lancet on April 29, 2020.

The number of people who experienced adverse side effects was roughly similar between those receiving remdesivir and those receiving a placebo. In 18 participants, the researchers stopped the drug treatment due to adverse reactions.

But then...

However, also on April 29, 2020, the National Institute of Allergy and Infectious Diseases (NIAID) announced that their NIH trial showed that remdesivir treatment led to faster recovery in hospital patients with COVID-19, compared with placebo treatment.

“Preliminary results indicate that patients who received remdesivir had a 31% faster time to recovery than those who received placebo,” according to the press release. “Specifically, the median time to recovery was 11 days for patients treated with remdesivir compared with 15 days for those who received placebo.”

The mortality rate in the remdesivir treatment group was 8%, compared with 11.6% in the placebo group, indicating that the drug could improve a person’s chances of survival. These data were close to achieving statistical significance.

And then...

“In addition, there is another Chinese trial, also stopped because the numbers of new patients with COVID-19 had fallen in China so they were unable to recruit, which has not yet published its data,” Prof. Evans continues. “There are other trials where remdesivir is compared with non-remdesivir treatments currently [being] done and results from some of these should appear soon.”

Gilead also put out its own press release about another clinical trial, which seems more focused on determining the optimal length of remdesivir treatment. Suffice it to say, there's still a lot of conflicting data and no clear information on whether or not remdesevir actually helps.

Still, that hasn't stopped people from trying to figure out just how much Gilead will price gouge going forward:

The Institute for Clinical and Economic Review (ICER), which assesses effectiveness of drugs to determine appropriate prices, suggested a maximum price of $4,500 per 10-day treatment course based on the preliminary evidence of how much patients benefited in a clinical trial. Consumer advocacy group Public Citizen on Monday said remdesivir should be priced at $1 per day of treatment, since “that is more than the cost of manufacturing at scale with a reasonable profit to Gilead.”

Some Wall Street investors expect Gilead to come in at $4,000 per patient or higher to make a profit above remdesivir’s development cost, which Gilead estimates at about $1 billion.

So... we've got a range of $10 to $4,500 on a treatment that we don't yet know works, and which may or may not save lives. But, given that we're in the midst of a giant debate concerning things like "reopening the economy" -- something that can really only be done if the public is not afraid of dying (or at least becoming deathly ill) -- the value to the overall economy seems much greater than whatever amount Gilead wants to charge. It seems the right thing to do -- again, if it's shown that remdesevir actually helps -- is to just hand over a bunch of money to Gilead, say "thank you very much" and get the drug distributed as widely as possible. Though, again, it should be noted that a decent chunk of the research around remdesevir was not done or paid for by Gilead, but (yet again) via public funds to public universities, which did the necessary research. The idea that it's Gilead that should get to reap massive rewards for that seems sketchy at best. But the absolute worst outcome is one in which Gilead sticks to its standard operating procedure and prices the drug in a way that millions of Americans can't afford it, and it leads to a prolonging/expanding of the pandemic.

Update used wrong data type, causing Tinder to Spotify to fall over

A change in the Facebook SDK backend managed to crash many popular iOS apps that integrated the code library, used for implementing various Facebook services.…

Компания обещает бесплатный ремонт устройств и возмещение расходов, если ноутбук уже отремонтировали.

Parents, kids: Fear not the silica gel pack. Sure it says DO NOT EAT and THROW AWAY. But you should only follow one of those rules.    Instead, save the packs and use them a whole lot of ways: Place them on the car dashboard by the windshield to keep it from fogging up.   […]

The National Highway Traffic Safety Administration (NHTSA) finds Tesla's Autopilot cuts crashes by 40%. How cool is that? Autonomous vehicles are going to cause a huge decline in accidents and deaths. Even short of autonomous vehicles, when you get your next car try to get one that supports automatic braking on imminent collision detection. You could get a large fraction of the collision avoidance benefit at a much lower cost today. Check out Insurance Institute for Highway Safety ratings of collision avoidance systems in current cars. Watch a Tesla react to a crash in front of it: Watch a Tesla avoid hitting a reckless driver: A recent analysis finds that autonomous vehicles will allow 2 million disabled people to get...

It’s not everyday we regurgitate a few old (and new!) chemistry jokes. How often do we tell them? Periodically. We told one the other day, but there was no reaction. Hahaha! Wait? How come nobody else is laughing? Ehem… well, anyways, here are a few more: When I first heard oxygen and magnesium got together […]

The post Top 20 Chemistry Jokes of Some Time appeared first on Funny & Jokes.

The post New Arrivals: Top Fishing Sunglasses You Can Try this 2020 appeared first on Ocean Blue Fishing Adventures.

The renaissance of complement diagnostics and therapeutics has introduced precision medicine into a widened field of complement-mediated diseases. In particular, complement-mediated diseases (or complementopathies) with ongoing or published clinical trials of complement inhibitors include paroxysmal nocturnal hemoglobinuria, cold agglutinin disease, hemolytic uremic syndrome, nephropathies, HELLP syndrome, transplant-associated thrombotic microangiopathy, antiphospholipid antibody syndrome, myasthenia gravis, and neuromyelitis optica. Recognizing that this field is rapidly expanding, we aim to provide a state-of-the-art review of (a) current understanding of complement biology for the clinician, (b) novel insights into complement with potential applicability to clinical practice, (c) complement in disease across various disciplines (hematology, nephrology, obstetrics, transplantation, rheumatology, and neurology), and (d) the potential future of precision medicine. Better understanding of complement diagnostics and therapeutics will not only facilitate physicians treating patients in clinical practice but also provide the basis for future research toward precision medicine in this field.

Facioscapulohumeral muscular dystrophy (FSHD) is caused by loss of repression of the DUX4 gene; however, the DUX4 protein is rare and difficult to detect in human muscle biopsies, and pathological mechanisms are obscure. FSHD is also a chronic disease that progresses slowly over decades. We used the sporadic, low-level, muscle-specific expression of DUX4 enabled by the iDUX4pA-HSA mouse to develop a chronic long-term muscle disease model. After 6 months of extremely low sporadic DUX4 expression, dystrophic muscle presented hallmarks of FSHD histopathology, including muscle degeneration, capillary loss, fibrosis, and atrophy. We investigated the transcriptional profile of whole muscle as well as endothelial cells and fibroadiopogenic progenitors (FAPs). Strikingly, differential gene expression profiles of both whole muscle and, to a lesser extent, FAPs, showed significant overlap with transcriptional profiles of MRI-guided human FSHD muscle biopsies. These results demonstrate a pathophysiological similarity between disease in muscles of iDUX4pA-HSA mice and humans with FSHD, solidifying the value of chronic rare DUX4 expression in mice for modeling pathological mechanisms in FSHD and highlighting the importance FAPs in this disease.

This week saw a couple of big announcements, led by the launch of an update for the 13-inch MacBook Pro line. Most notably, the update brought the improved Magic Keyboard previously introduced on its 16-inch sibling and the MacBook Air, with high-end models also receiving updated processors.

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The second significant announcement this week was that Apple's first all-digital Worldwide Developers Conference will kick off on June 22. Other news this week included a firmware update for the AirPods Pro, an update on Apple's Mini-LED efforts, and more.

Read on below and check out our video above for recaps of all of this week's most important stories!

New 13-Inch MacBook Pro Announced With Magic Keyboard, 10th-Gen Processors, Up to 32GB RAM and 4TB SSD, and More

Apple this week refreshed its 13-inch MacBook Pro lineup, with key features including the same Magic Keyboard as the 16-inch MacBook Pro, up to 80 percent faster Intel graphics than the previous generation, up to 32GB of RAM, up to 4TB of SSD storage, and 6K display support.


First introduced on the 16-inch MacBook Pro last year, the Magic Keyboard features a far more reliable scissor mechanism with 1mm of key travel. After five years, Apple has finally transitioned its entire notebook lineup away from its issue-prone butterfly keyboard.

10th-generation Intel processor options are only available on higher-end models, with the $1,799 configuration proving to be up to 16.5% faster than the $1,299 base model with an older 8th-generation processor.

Apple's Virtual WWDC Event to Kick Off on June 22

Apple has announced that its first-ever online-only WWDC will begin Monday, June 22 via the Apple Developer app and website. The weeklong event will include a virtual keynote, sessions, and labs, with more details to be shared in June. And it's free!


Apple is expected to introduce iOS 14, iPadOS 14, macOS 10.16, tvOS 14, and watchOS 7 at WWDC 2020, with beta testing to take place over the summer.

Student developers from all over the world can enter Apple's Swift Student Challenge by creating an interactive scene in Swift Playgrounds that can be experienced in three minutes. Winners will receive an exclusive WWDC20 jacket and pin set. Submissions are open through May 17.

Apple Updates AirPods Pro Firmware to Version 2D15

Apple this week released a new firmware version 2D15 for the AirPods Pro, replacing version 2C54.


In recent months, some AirPods Pro owners have been complaining about reduced noise cancellation and crackling or static sounds, so users have listened for any improvements following the update.

Perhaps proving how subjective sound quality can be, feedback has been decidedly mixed, with some users noticing an improvement, some noticing no change, and some noticing further degradation to noise cancellation.

Apple has offered some help in the form of two new support documents for users to troubleshoot noise cancellation or crackling sound issues.

10 Tips and Tricks for the iPad Pro Magic Keyboard

Have you recently picked up a new Magic Keyboard for the iPad Pro? Here's a list of our favorite tips and tricks that you need to know.


The tips and tricks relate to adjusting the backlight brightness, customizing the cursor's behavior, enabling tap-to-click on the trackpad, other trackpad gestures, accessing the Emoji keyboard, and more.

Apple's Mini-LED Product Roadmap May Have Been Pushed Back to 2021

Disappointed that the new 13-inch MacBook Pro was not the rumored 14-inch model? That may be due to a slight delay in Apple's plans to release a range of new products with Mini-LED backlit displays.

Kuo believes Apple's first Mini-LED products might not launch until 2021. The analyst has previously said these products would include a new 14.1-inch MacBook Pro, 16-inch MacBook Pro, 12.9-inch iPad Pro, and more.


Kuo has previously said that Mini-LED displays will allow for thinner and lighter product designs, while offering many of the same benefits of OLED displays used on the latest iPhones, including good wide color gamut performance, high contrast and dynamic range, and local dimming for truer blacks.

NFC-Based Digital Key Specification Released Ahead of Apple's Rumored CarKey Feature on iPhone

Amid rumors that Apple is working on a digital "CarKey" feature for iPhone, the Car Connectivity Consortium has announced that its NFC-based Digital Key Release 2.0 specification has been finalized and made available to its members, which includes Apple.


"CarKey" will allow an iPhone or Apple Watch to unlock, lock, and start an NFC-compatible vehicle. Just like credit cards and boarding passes, users will be able to add a digital car key to the Wallet app, eliminating the need to use a physical car key or key fob.

MacRumors Newsletter

Each week, we publish an email newsletter like this highlighting the top Apple stories, making it a great way to get a bite-sized recap of the week hitting all of the major topics we've covered and tying together related stories for a big-picture view.

So if you want to have top stories like the above recap delivered to your email inbox each week, subscribe to our newsletter!
This article, "Top Stories: New 13" MacBook Pro, WWDC Starts June 22, AirPods Pro Firmware Update, and More" first appeared on MacRumors.com

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Accountants CPA Hartford Connecticut LLC:  This transcript may contain errors. The Willis Report:  And tonight’s stunning accusation against Intuit, the maker of Turbotax, the popular tax preparation software.  Two whistleblowers claim that Intuit knew that criminals used its tax software … Continue reading →

Berlin needs an independent candidate on its Town Council to counter and prevent the dominance of a major political party from unilaterally imposing its agenda and will on the citizens of Berlin. Our Town Council has been voting along strict party lines on key issues even though members pledged to reach across the aisle. It has dismissed or circumvented the results of referendums, reducing them to mere dog-and-pony shows. Berlin has more unaffiliated voters than those of the two major parties. Let's petition, nominate, and place on the ballot an independent candidate to represent these citizens and prevent the control of our Town by the dominant party on the Town Council. If interested, please contact us: berlinctpropertyownersassn@gmail.com. Continue reading →

we know how politics works in the United States. Whoever—whatever political party gets into government is going to merge with the bureaucracy pretty damn fast. It will be in a position where it has some levers in its hand. And so, as a result, corporate lobbyists will move in to help control those levers. So it doesn’t make much difference in the end. What does make a difference is political accountability, a general deterrence set to stop political organizations behaving in a corrupt manner. Continue reading →

Noor asks Hedges how the presidential nominees should respond to these types of terrorist attacks in the U.S. “Their response should be the end of the occupation in the Middle East and the cessation of saturation bombing by drones and military aircrafts and missiles in parts of Iraq and Syria and Pakistan and Yemen and Somalia,” Hedges responds. He goes on to explain how decades of foreign policy decisions made by both parties have created the circumstances for terrorist attacks. Continue reading →

"Trump didn’t hijack the populism, the Democratic Party made a gift of it to him. And he simply accepted it. … that elite … made a decision that in the midst of a global insurrection against political corruption and economic oligarchy that Hillary Clinton’s 'pay to play' politics in global finance capitalism would somehow play better than Bernie Sanders Democratic Socialism. … they ignored every poll they had, all the data they had, and even all the anecdotes they could possibly have accumulated in order to reach the conclusion that Hillary was a stronger candidate than Bernie. … And I remain certain that if anyone other than Clinton - and certainly if you accept for just one moment that when all the polls said the right things by such wide margins for so long they might be right - Bernie Sanders could have won this had he been the nominee, like Roosevelt took out Landon." Continue reading →

Root cause analysis is one of the best ways to solve difficult or significant problems, but sometimes, root cause analysis efforts fail because the corrective actions weren't effective. If the original problem happens again, or the needed improvements haven't materialized, or a new problem arises because of the corrective actions, you need to figure out what happened […]

NOT. HAPPY. AUSTRALIA! ScoMo offers some plain speakin’ to a country in chaos.  Plus, the media embrace social distancing. And a CNN interview turns into family therapy. 

What if you made it more comfortable to sleep at a bus stop?

A batch of advice for visiting Disneyland with two young teens

IBM Watson Health™ today published its 100 Top Hospitals® annual study identifying top–performing hospitals in the U.S. based on overall organizational performance. Formerly known as the Truven Health Analytics® 100 Top Hospitals, this study spotlights the best–performing hospitals in the U.S. based on a balanced scorecard of publicly available clinical, operational, and patient satisfaction metrics and data. It has been conducted annually since 1993.

IBM inventors received a record 9,043 patents in 2017, marking the company’s 25th consecutive year of U.S. patent leadership and crossing the 100,000-patent milestone. The new patents were granted to a diverse group of more than 8,500 IBM researchers, engineers, scientists and designers in 47 different U.S. states and 47 countries.

IBM today announced that it set a new U.S. patent record in 2011, marking the 19th consecutive year that the company has led the annual list of patent recipients. IBM inventors earned a record 6,180 U.S. patents in 2011, more than quadrupling Hewlett-Packard’s issuances and exceeding by six times those of Oracle/Sun.

Declares Intent to Break the Exaflop Barrier; Develops Exascale Research Collaboratory in Dublin

IBM today announced that it received a record 6,478 patents in 2012 for inventions that will enable fundamental advancements across key domains including analytics, Big Data, cybersecurity, cloud, mobile, social networking and software defined environments, as well as industry solutions for retail, banking, healthcare, and transportation. These patented inventions also will advance a major shift in computing, known as the era of cognitive systems.

IBM Security today announced a new capability from IBM Trusteer that helps banks identify fraudulent accounts before they are opened. The technology also protects consumers even if they are not a customer of the bank being targeted with the fake account.

IBM (NYSE: IBM ) today announced the local availability of the Virtual Desktop for Smart Business, a new workforce mobility solution offering anytime, anywhere, access to corporate data from mobile devices, such as tablets or laptops on the move.

In the latest episode of their feathery but unruffled podcast, Ken and Robin talk history spoilers, political pigeons, Sarah Bernhardt, and the Dark Watchers.

Professional and high-performance athletes in Spain were allowed to return to practice, but some were jeered for doing so during the coronavirus pandemic.

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In the comments to these weekly posts (and only these posts), it's your chance to go as off topic as you like. Talk about non-comics stuff, thread derail, and just generally chat among yourselves.

The EU hosted a summit where over 40 countries and global organisations promised a starting figure of over $8 billion to the development of a covid-19 vaccine.

Much of the world is starting to experiment with opening up again in a new sort-of-post-Covid19 world, with places like Germany and Spain relaxing, gradually, some of the lockdown protocols, with strong limitations and provisos.

In New Zealand, consistent reminder that competent politicians exist Jacinda Ardern has suggested that the country may not have open borders for a long time to come.

In the UK, a phone app is being developed for contact tracingM and notification of people you may have been in contact with who develop Covid19, though in true current UK style, it's going against every other countries developed app by not using the personalised data storage method (Where your information never leaves your phone), but a centralised database, which is raising some concerns about the storage and disposal (or not) of this data.

The US government is planning on borrowing around 3 TRILLION dollars in the next quarter to pay for pandemic support initiatives. That's 3,000,000,000,000 (Which I only mention because I've never had a reason to type an actual number that big in a real world context!)

The US is also starting to open up in places, though the wisdom of this is being called into question by... well, pretty much everyone else on the planet, and a goodly number of the local population of course.

The Clone Wars seventh and final season came to an end with a frankly spectacular arc which saw Ahsoka Tano facing off against Darth Maul in the sort of iconic fight scene that, truth be told, the sequel trilogy was mostly completely lacking, at least on an emotional level), and giving us a chance to see the impact of General Order 66 from the point of view of Ahsoka, as well as the actual Clone Troopers who we have got to know and care about over the years of this series. THIS is how you do it!

The long overdue, repeatedly delayed, New Mutants movie was briefly appearing as forthcoming video on demand from Amazon, though without a release date, but it has now disappeared again. This DOES seem to suggest it might go straight to digital with no cinema release.

Also a new image of a new baddies form the movie have been released in the shape of the Smiley-Men.

And I've clearly been watching waaaay too much anime, or at least listening to too many anime soundtracks when a random video from something called Argonavis (A games based anime from what I can see) popped up and I thought "Gosh that sounds like Unison Square Garden" (who did "Orion o Nazoru", the belter of an OP for Tiger and Bunny) only to discover it's not, but it was written and arranged by two of the members.

In terms of podcasts, alongside old favourites like "Jay and Miles X-Plain the X-Men" (pretty much what it says on the tin and currently looking at Age of Apocalypse), "The NoSleep Podcast" (Horror fiction) and "The Arkham Sessions" (An actual qualified clinical psychologist, Dr Andrea Letamendi, examined, firstly "Batman the Animated Series" and is now looking at the "Doom Patrol" TV series for their depictions of mental conditions), I've just started Mockery Manor, a horror/mystery/drama set at a gloriously awful (and thankfully fictional) British theme park in the late 1980's.

So today's extra curricular activity for the community: What podcasts are you currently listening to that you'd recommend to others?


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