été A novel, glutathione-activated prodrug of pimasertib loaded in liposomes for targeted cancer therapy By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00517A, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Arianna Amenta, Susanna Comi, Marcelo Kravicz, Silvia Sesana, Antonia Antoniou, Daniele Passarella, Pierfausto Seneci, Sara Pellegrino, Francesca ReA novel, glutathione-activated prodrug of pimasertib (PROPIMA) has been developed. PROPIMA showed ability to inhibit tumour cell migration and proliferation controlled over time, while also achieving a high incorporation rate into liposomes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Inhibition of monoamine oxidases by heterocyclic derived conjugated dienones: synthesis and in vitro and in silico investigations By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00608A, Research ArticleSunil Kumar, Bishnu Prasad Pandey, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Rania B. Bakr, Hoon Kim, Bijo MathewA total of 18 heterocyclic derived conjugated dienones (CD1–CD18) were evaluated for their potential monoamine oxidase (MAO)-A/-B inhibitory activity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Development, biological evaluation, and molecular modelling of some benzene-sulfonamide derivatives as protein tyrosine phosphatase-1B inhibitors for managing diabetes mellitus and associated metabolic disorders By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00594E, Research ArticleNagat Ghareb, Khaled M. Darwish, Mohamed S. Nafie, Ranwa Elrayess, Noha M. Abourobe, Shaimaa A. Fattah, Reem M. Hazem, Eman T. Mehanna, Ranza ElrayessOne benzene-sulfonamide derivative exhibited potent protein tyrosine phosphatase-1B inhibition for managing diabetes mellitus and associated metabolic disorders.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été A decade of pyridine-containing heterocycles in US FDA approved drugs: a medicinal chemistry-based analysis By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00632A, Review ArticleAshish Ranjan Dwivedi, Shivani Jaiswal, Deepak Kukkar, Roshan Kumar, Thakur Gurjeet Singh, Mahendra Pratap Singh, Abhay M. Gaidhane, Sorabh Lakhanpal, K. Nagendra Prasad, Bhupinder KumarThe present review is a concerted effort to cover drugs bearing pyridine rings approved in the last decade, and it provides thorough discussion and commentary on their pharmacokinetics and pharmacodynamics together with in-depth structural analysis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Tiruchi district SHGs compete to prepare healthy millet-based recipes at food festival By www.thehindu.com Published On :: Fri, 08 Nov 2024 07:51:25 +0530 Women entrepreneurs urged to take advantage of social media platforms to advertise and market their products to a wider customer base Full Article Tiruchirapalli
été New venture Zerofifty from ad veterans wants to simplify the agency model By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 10:46:58 +0530 ZeroFifty Mediaworks, set up by three ad veterans, wants to bring in Bandra vibes into the agency model Full Article Marketing
été Diamonds are a UV photodetector’s best friend By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 21:34:55 +0530 How lab-grown rocks from Surat are set to power the development of high-performance electronics Full Article Science and Technology
été ARRL Opening Late on Friday, Nov. 8 and Closed on Veterans Day, Nov. 11 By www.arrl.org Published On :: Thu, 07 Nov 2024 13:42:00 -0600 ARRL® The National Association for Amateur Radio® has two closures coming up for our headquarters in Newington, Connecticut:ARRL will be closed on Friday morning, November 8, 2024, for an employee meeting. During the short closure, members are encouraged to use the ARRL website, www.arrl.org, for membership renewals, publication purchases, and to access most benefits, services, and programs. T... Full Article
été Babar named 'Most Valuable Cricketer' in PCB Awards By www.rediff.com Published On :: Fri, 01 Jan 2021 21:05:46 +0530 In the four Tests played during the year, Babar scored 338 runs at an average of 67.6. Full Article Babar Azam PCB Mount Maunganui Kamran Ghulam Naseem Shah Khyber Pakhtunkhwa Aliya Riaz Mohammad Rizwan Fawad Alam Fatima Sana Twitter New Zealand South Africa Bangladesh Pakistan
été 'He's the most valuable cricketer right now' By www.rediff.com Published On :: Sun, 15 Sep 2024 15:37:06 +0530 Since making his Test debut in 2018, Bumrah has made 36 Test appearances and has 159 wickets to his name. Full Article
été Karaikal police round up history-sheeters under ‘Operation Trishul’ By www.thehindu.com Published On :: Sun, 10 Nov 2024 20:25:35 +0530 Eight long-pending non-bailable warrants were successfully executed, and two arrests made under the Arms Act for possession of dangerous weapons Full Article Tiruchirapalli
été T.N. stretch of Bengaluru-Chennai Expressway may be completed by August 2025 By www.thehindu.com Published On :: Sun, 10 Nov 2024 22:17:27 +0530 While the 24.50-km package from Walajapet to Arakkonam has the most progress, with over 84% of the work being carried out, the Arakkonam to Kancheepuram package has the least progress with about 52% Full Article Chennai
été Organic/inorganic heterostructures templated by interfacial instability-driven BCP colloids in deformable emulsion droplets By pubs.rsc.org Published On :: Soft Matter, 2024, 20,8174-8180DOI: 10.1039/D4SM00921E, CommunicationYuqing Song, Nan Yan, Lingli Wan, Jingjing Li, Ye GaoCore–shell colloids are self-assembled in emulsion droplets driven by interfacial instability, which serve as excellent scaffolds for designing organic/inorganic heterostructures.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Nature of barriers determines first passage times in heterogeneous media By pubs.rsc.org Published On :: Soft Matter, 2024, 20,8353-8362DOI: 10.1039/D4SM00908H, PaperMoumita Dasgupta, Sougata Guha, Leon Armbruster, Dibyendu Das, Mithun K. MitraThe nature of barriers control the first passage times in heterogenous media. For entropic barriers, the first passage times increases monotonically with increasing number of barriers, while for energetic barriers, passage times show a non-monotonic behaviour with increasing barriers.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Self-assembly of amphiphilic homopolymers grafted onto spherical nanoparticles: complete embedded minimal surfaces and a machine learning algorithm for their recognition By pubs.rsc.org Published On :: Soft Matter, 2024, 20,8385-8394DOI: 10.1039/D4SM00616J, PaperD. A. Mitkovskiy, A. A. Lazutin, A. L. Talis, V. V. VasilevskayaAmphiphilic macromolecules grafted onto spherical nanoparticles can self-assemble into morphological structures corresponding to the family of complete embedded minimal surfaces. They arise situationally, can coexist and transform into each other.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Chronicles of a triathelete By www.thehindu.com Published On :: Mon, 11 Jul 2016 16:41:58 +0530 Anu Vaidyanathan talks about her journey as a triathelete in her memoir Anywhere but Home Full Article Athletics
été Time to act against early-onset diabetes By www.thehindu.com Published On :: Sat, 12 Nov 2016 17:24:08 +0530 Catching diabetes in its early stages could mean lesser complications later Full Article Fitness
été ICICI Prudential Multi asset completes 22 years By www.thehindubusinessline.com Published On :: Mon, 11 Nov 2024 14:51:39 +0530 A lump sum investment of ₹10 lakh at the time of inception in October 31, 2002 will be worth about ₹7.26 crore given compounded annual growth rate of 22 per cent Full Article Money & Banking
été The Agony of Jimmy Quinlan / directed by: George Mihalka, George Williams ; produced by: Robert Duncan, Janice Brown, Andy Thomson, Peter Katadotis ; production agency: National Film Board of Canada (Montreal) By darius.uleth.ca Published On :: Montreal : National Film Board of Canada, 2008 Full Article
été Nandyal collector asks officials to complete land acquisition By www.thehindu.com Published On :: Mon, 11 Nov 2024 18:30:01 +0530 Full Article Andhra Pradesh
été Research problems in discrete geometry [electronic resource] / Peter Brass, William Moser, Janos Pach By darius.uleth.ca Published On :: New York : Springer, 2005 Full Article
été Riemannian geometry [electronic resource] / Peter Petersen By darius.uleth.ca Published On :: New York : Springer, [2006] Full Article
été Point process theory and applications [electronic resource] : marked point and piecewise deterministic processes / Martin Jacobsen By darius.uleth.ca Published On :: Boston : Birkhäuser, [2006] Full Article
été Principles of computational fluid dynamics [electronic resource] / Pieter Wesseling By darius.uleth.ca Published On :: Berlin ; Heidelberg : Springer-Verlag, 2009, 2001 Full Article
été Problems and theorems in classical set theory [electronic resource] / Peter Komjath, Vilmos Totik By darius.uleth.ca Published On :: New York ; Berlin : Springer, 2006 Full Article
été Samithi to hold collective dharna on November 26 demanding complete restoration of Nanthoor-Surathkal stretch of NH 66 By www.thehindu.com Published On :: Thu, 07 Nov 2024 07:00:00 +0530 Preparatory meeting highlights battered carriageway stretch, absence of service roads and shoulder drains and delayed execution of new bridge at Kulur Full Article Mangaluru
été NEP 2020: Michel Danino advocates ‘complete overhaul’ of school education By www.thehindu.com Published On :: Wed, 06 Nov 2024 17:23:51 +0530 The Hindu’s webinar discusses NEP 2020’s changes in Indian education with prominent educationists. Full Article Education
été Pete’s Dragon: a winsome Disney adventure By www.thehindu.com Published On :: Fri, 19 Aug 2016 17:26:46 +0530 Full Article Reviews
été Brookfield-led consortium completes acquisition of American Tower’s operations in India By www.thehindubusinessline.com Published On :: Thu, 12 Sep 2024 19:30:34 +0530 The acquisition, valued at $2.2 billion, encompasses approximately 76,000 communications sites, solidifying the consortium’s commitment to advancing India’s connectivity Full Article Real Estate
été Visible-light heterogeneous photocatalysis with an ionic porous organic polymer (IPOP): synthesis of β-keto sulfoxides and benzothiophene diesters by tandem radical addition–oxidation reactions By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01382D, Research ArticleAjay Kumar Sahoo, Parag Tamuly, Jarugu Narasimha MoorthyAn IPOP, constructed constructed from cyanuric chloride and the readily accessible 2,5-di(pyridin-4-yl)thiazolo[5,4-d]thiazole (BpyTzTz), is shown to exhibit excellent visible light absorption and serve as a metal-free heterogeneous photocatalyst.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été I2-Promoted oxidative annulation of three different amines to access diverse biheteroaryls By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01801J, Research ArticleGuangping Fan, Penghui Cao, Fang Bai, Yanyan Yin, Xueyan Hou, Yani Liu, Zhenzhen Xing, Yanhui Wang, Tangqiang Sun, Qinghe GaoAn I2-promoted oxidative annulation of three different amines enables the assembly of nonsymmetrical 2,2'-biquinolines and related bis-azines through a [4π + 2σ] annulation reaction.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Stereoselective access to furan-fused [5.5.0] bicyclic heterocycles enabled by gold-catalyzed asymmetric [8 + 4] cycloaddition By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01841A, Research ArticleXunhua Wang, Jianhua Wang, Xiaoxun LiA gold-catalyzed asymmetric [8 + 4] cycloaddition was developed to afford highly functionalized furan/pyrrole-fused [5.5.0] polycyclic heterocycles with good diastereo- and enantioselectivity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Structure determination of difficult-to-crystallize organic molecules by co-crystallization of a phosphorylated macrocycle By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6358-6366DOI: 10.1039/D4QO01498G, Research ArticleHeng Li, Zhijin Li, Juli Jiang, Chen Lin, Leyong WangThis work reported that 37 different difficult-to-crystallize guest molecules were co-crystallized with the host macrocycle F[3]A1-[P(O)Ph]3 at room temperature, and the molecular structures of the guests could be determined by SCXRD.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été A pillar[5]arene-based three-component supramolecular copolymer for the fluorescence detection of spermine By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6293-6303DOI: 10.1039/D4QO01470G, Research Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Martina Mazzaferro, Daniele Crisafulli, Francesca Mancuso, Marco Milone, Fausto Puntoriero, Anna Irto, Salvatore Patanè, Valentina Greco, Alessandro Giuffrida, Ilenia Pisagatti, Anna Notti, Melchiorre F. Parisi, Giuseppe GattusoA supramolecular copolymer, composed of a bis-pillar[5]arene diacid and complementary alkylidene- and perylene-bisimide-bis-imidazole comonomers, acts as an OFF/ON luminescent sensor for spermine.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Nickel-catalysed enantioselective cross-electrophile coupling reaction with the retention of the β-fluorine atom By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6459-6469DOI: 10.1039/D4QO01555J, Research ArticleXin-Yi Shi, Xueyuan Yan, Xiaodong Tang, Shi-Jing Zhai, Genping Huang, Jun-An Ma, Fa-Guang ZhangA nickel-catalysed enantioselective reductive cross-coupling reaction of a new monofluoromethyl building block with acid chlorides is developed to give chiral α-monofluoromethyl acyloin derivatives.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Dendron-mediated control over self-assembly of chlorophyll rosettes into columnar vs. discrete aggregates By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6304-6310DOI: 10.1039/D4QO01629G, Research Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ryo Kudo, Hiroki Hanayama, Balaraman Vedhanarayanan, Hitoshi Tamiaki, Nobuyuki Hara, Sarah E. Rogers, Martin J. Hollamby, Biplab Manna, Koji Harano, Shiki YagaiBy controlling the π-π stacking of chlorophyll supramolecular rosettes through steric hindrance of alkyl dendrons, it become possible to create chlorophyll tubes and discrete rings that resemble to natural chlorophyll assemblies.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Recent advances in asymmetric synthesis of chiral benzoheterocycles via Earth-abundant metal catalysis By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6534-6557DOI: 10.1039/D4QO01686F, Review ArticleJinhui Cai, Wenting Zhang, Usman Muhammad, Weishuang Li, Yanjun XieThis review mainly focus on the assembly of chiral benzoheterocycles, such as dihydrobenzofurans, chromans, indolines, tetrahydroquinolines, etc., via Earth-abundant metal-catalyzed (Cu, Fe, Ni, and Ti) asymmetric synthesis in the last few decades.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Catalyst-free C–H methylation of heteroarenes enabled by electron donor–acceptor complex photoactivation By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01309C, Research ArticleJiayang Wang, Baoer Shao, Haixia Ge, Huiyu Xue, Xiangyuan Ding, Yuqi Li, Peiyao ShengA visible-light-induced direct C–H methylation of heterocycles (including quinoxalinones, pyrazinones, quinolinones and coumarins) with methylamines via EDA complex photoactivation was developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Stereocontrolled synthesis of heterocycles from unactivated alkynes by photoredox/nickel dual-catalyzed cyclization By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01627K, Research ArticleBo-Rong Leng, Feng Yang, Jin-Lian Bai, Yu-Wen Huang, Qing-Quan Liu, Ping Wei, De-Cai Wang, Yi-Long ZhuWe report a nickel/photoredox dual catalysis method for synthesizing heterocyclics from unactivated alkynes and aryl iodides, offering a direct, selective, and green alternative to traditional synthesis with potential in medicinal chemistry.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été CM Revanth Reddy announces resolve to complete pending projects of Palamuru district By www.thehindu.com Published On :: Sun, 10 Nov 2024 23:43:29 +0530 Criticises opposition parties for trying to create obstacles in district development Full Article Telangana
été I will prove my that my retention was right decision: Shashank By www.thehindu.com Published On :: Fri, 01 Nov 2024 16:16:44 +0530 Shashank established himself as a fine finisher for Punjab Kings in the last season where he was their top run-getter with 354 runs at a strike rate of 164.65. He averaged 44.25. Full Article Cricket
été I want to be a complete batter and a complete spinner: Tanush Kotian’s mission statement By www.thehindu.com Published On :: Fri, 01 Nov 2024 23:35:04 +0530 The Mumbai all-rounder’s consistent match-winning feats have catapulted him into national reckoning. Judging by the challenges he has overcome so far, as well as his clear-headed approach to cricket, the 26-year-old will be keen to test himself on India-A’s tour of Australia Full Article Cricket
été The Complete to Planning Your Estate in Florida: A Step-by-Step Plan to Protect Your Assets, Limit Your Taxes, and Ensure Your Wishes are Fulfilled for Florida Residents By atlanticpub.wordpress.com Published On :: Tue, 31 Jul 2012 19:34:40 +0000 What happens to your estate after you are gone is very much within your control. Estate planning is not only for the wealthy; it is for everyone. It is simply the process of deciding where your assets are to be distributed after your death. For those people who wish to preserve their assets for designated […] Full Article Publisher
été The Complete to Planning Your Estate in Pennsylvania: A Step-by-Step Plan to Protect Your Assets, Limit Your Taxes, and Ensure Your Wishes are Fulfilled for Pennsylvania Residents By atlanticpub.wordpress.com Published On :: Tue, 31 Jul 2012 19:36:37 +0000 What happens to your estate after you are gone is very much within your control. Estate planning is not only for the wealthy; it is for everyone. It is simply the process of deciding where your assets are to be distributed after your death. For those people who wish to preserve their assets for designated […] Full Article Publisher
été The Complete to Planning Your Estate in Michigan: A Step-by-Step Plan to Protect Your Assets, Limit Your Taxes, and Ensure Your Wishes are Fulfilled for Michigan Residents By atlanticpub.wordpress.com Published On :: Tue, 31 Jul 2012 19:37:54 +0000 What happens to your estate after you are gone is very much within your control. Estate planning is not only for the wealthy; it is for everyone. It is simply the process of deciding where your assets are to be distributed after your death. For those people who wish to preserve their assets for designated […] Full Article Publisher
été The Complete to Planning Your Estate in Georgia: A Step-by-Step Plan to Protect Your Assets, Limit Your Taxes, and Ensure Your Wishes are Fulfilled for Georgia Residents By atlanticpub.wordpress.com Published On :: Tue, 31 Jul 2012 19:39:15 +0000 What happens to your estate after you are gone is very much within your control. Estate planning is not only for the wealthy; it is for everyone. It is simply the process of deciding where your assets are to be distributed after your death. For those people who wish to preserve their assets for designated […] Full Article Publisher
été The Complete to Planning Your Estate in Virginia: A Step-by-Step Plan to Protect Your Assets, Limit Your Taxes, and Ensure Your Wishes are Fulfilled for Virginia Residents By atlanticpub.wordpress.com Published On :: Tue, 31 Jul 2012 19:40:29 +0000 What happens to your estate after you are gone is very much within your control. Estate planning is not only for the wealthy; it is for everyone. It is simply the process of deciding where your assets are to be distributed after your death. For those people who wish to preserve their assets for designated […] Full Article Publisher
été The Complete to Planning Your Estate in Washington: A Step-by-Step Plan to Protect Your Assets, Limit Your Taxes, and Ensure Your Wishes are Fulfilled for Washington Residents By atlanticpub.wordpress.com Published On :: Tue, 31 Jul 2012 19:44:24 +0000 What happens to your estate after you are gone is very much within your control. Estate planning is not only for the wealthy; it is for everyone. It is simply the process of deciding where your assets are to be distributed after your death. For those people who wish to preserve their assets for designated […] Full Article Publisher
été Enhanced surface functionalization of 2D molybdenum/tin chalcogenide nanostructures for effective SERS detection of Escherichia coli By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35021-35034DOI: 10.1039/D4RA05315J, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Zainab Ishfaq, Layla A. Almutairi, M. Yasir Ali, Salhah Hamed Alrefaee, Mohamed Abdelsabour Fahmy, Elsammani Ali Shokralla, Lamiaa G. Alharbe, Adnan Ali, Arslan Ashfaq, A. R. Abd-ElwahedThis study enhances MoS2/SnS2 nanoparticles for SERS, functionalizing them with L-cysteine. Successful detection of E. coli demonstrates their potential as cost-effective SERS substrates for real-world applications.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
été Investigation of the titanium-mediated catalytic enantioselective oxidation of aryl benzyl sulfides containing heterocyclic groups By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35105-35113DOI: 10.1039/D4RA07088G, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maria Annunziata M. Capozzi, Angel Alvarez-Larena, Joan F. Piniella Febrer, Cosimo CardellicchioEnantiopure benzyl heteroaryl sulfoxides were obtained by asymmetric oxidation. However, two benzimidazolyl sulfoxides were found to be conglomerates.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
