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P3MOT-decorated metal-porphyrin-based zirconium-MOF for the efficient electrochemical detection of 4-nitrobenzaldehyde

Anal. Methods, 2024, 16,2093-2100
DOI: 10.1039/D4AY00152D, Paper
Wen-yi Chen, Xin-yu Huang, Qian Sun, En-qing Gao
Developed a novel hybrid P3MOT@PCN-222(Fe) via in situ polymerization for 4-NBA detection. Showcased broad detection range, high sensitivity, selectivity and stability, laying groundwork for environmental monitoring.
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Sodium alginate hydrogelation mediated paper-based POCT sensor for visual distance reading and smartphone-assisted colorimetric dual-signal determination of L-lactate

Anal. Methods, 2024, 16,2077-2084
DOI: 10.1039/D4AY00041B, Paper
Wenjuan Wang, Danrong Chen, Yujiao Cai, Zijing Liu, Hongfen Yang, Hongbin Xie, Jinquan Liu, Shengyuan Yang
Here, we show a paper-based POCT sensor based on lactate dehydrogenase-mediated alginate gelation combined with visual distance reading and smartphone-assisted colorimetric dual-signal analysis to determine the concentration of L-lactate in yogurt samples.
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été

An electrochemiluminescence microsensor based on DNA-silver nanoclusters amplification for detecting cellular adenosine triphosphate

Anal. Methods, 2024, 16,2019-2024
DOI: 10.1039/D4AY00212A, Paper
GuanQi Wu, Jian Chen, JinXin Dou, XiangWei He, Hai-Fang Li, Jin-Ming Lin
An ECL microsensor integrating RCA magnification and in situ DNA-templated AgNC generation for sensitive detection of cellular ATP.
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été

High performance and recyclable Ag/ZnO/PM substrate for the detection of organic pollutants

Anal. Methods, 2024, 16,2051-2062
DOI: 10.1039/D4AY00103F, Paper
Yixin Shao, Hongxin Cai, Lingling Yan, Hang Yu, Qiang Hu, Liang Chen, Haitao Zong, Xiufang Hou
A sensitive and recyclable substrate was fabricated through in situ reduction of silver nanoparticles on zinc oxide nanorods.
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A novel multifunctional SERS microfluidic sensor based on ZnO/Ag nanoflower arrays for label-free ultrasensitive detection of bacteria

Anal. Methods, 2024, 16,2085-2092
DOI: 10.1039/D4AY00018H, Paper
Yue Liu, Guanwen Su, Wei Wang, Hongyuan Wei, Leping Dang
Design and working principle of bacterial capture and identification using a ZnO/Ag microfluidic SERS sensor array.
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été

Construction of a three-mode sensor based on gold nanoparticles and carbon quantum dots as probes for the detection of thiosemicarbazone

Anal. Methods, 2024, 16,2127-2134
DOI: 10.1039/D4AY00256C, Paper
Zhili Liu, Xiaojun Wang, Jing Li, Wenfeng Zhou, Haixiang Gao, Runhua Lu
A three-mode sensor for thiocarbazone (TSC) was constructed based on gold nanoparticles and carbon quantum dots (CQDs). (A) Synthesis process of CQDs using ginkgo leaves. (B) Colorimetric and chrominance TSC detection. (C) Fluorescence detection of TSC.
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A screening method for the quantitative determination of selective androgen receptor modulators (SARMs) in capsules by high resolution 19F- and 1H-NMR spectroscopy

Anal. Methods, 2024, 16,2135-2146
DOI: 10.1039/D4AY00188E, Paper
Alessandro Maccelli, Anna Borioni, Federica Aureli, Maria Cristina Gaudiano, Livia Manna, Mariangela Raimondo
A new method for rapid determination of selective androgenic receptor modulators (SARMs) andarine, cardarine, ligandrol, ostarine and S-23 in capsules by 1H- and 19F-high resolution NMR spectroscopy was described and validated.
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été

Electrochemical aptasensor based on silver-thiolated graphene for high-sensitive detection of Pb2+

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00322E, Paper
Jie Zhou, Changchun Hu, Shuo Li, Chuanxiang Zhang, Yuan Liu, Zhu Chen, Song Li, Hui Chen, Yan Deng
The presence of lead ions (Pb2+) not only leads to environmental contamination but also poses a significant risk to public health through their migration into food and drinking water. Therefore,...
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Luminescent and time-resolved determination of gemifloxacin mesylate in pharmaceutical formulations and spiked blood plasma samples using a lanthanide complex as a probe

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00236A, Paper
Gasser M. Khairy, Rania M. Goda, Zeinab M. Anwar, Mohamed M. Aboelnga, Axel Duerkop
A new luminescent europium probe for the determination of the antibiotic gemifloxacin is presented. Time-resolved luminescence enables its quantitation in pharmaceutical formulations and blood samples.
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été

A lateral flow strip for on-site detection of homocysteine based on a truncated aptamer

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00274A, Paper
Yunqing Wu, Tianyu Huang, Xin Chen, Mingyuan Wang, Xiaoli Wang, Yuting Zhang, Nandi Zhou
A lateral flow strip based on a truncated aptamer for on-site detection of homocysteine in human serum.
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été

PCB-C4D coupled with paper-based microfluidic sampling for the rapid detection of liquid conductivity

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00198B, Paper
Mingpeng Yang, Mingyi Cao, Zhixuan Zhang, Chaofan Wang
A solution conductivity detection method, using PCB-C4D coupled with paper-based microfluidic sampling, has been proposed for the rapid and in situ analysis of raw solution with particle filtration, improving detection consistency and reliability.
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été

Direct detection of dithiocarbamate fungicides by SALDI/MS using porous TiC ceramic powder as a substrate

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY01533E, Paper
Hiroshi Moriwaki, Issey Osaka, Kotaro Hashimoto, Osamu Yamada
Direct detection of dithiocarbamate fungicides (DTCs) has been achieved by SALDI/MS using porous titanium carbide (TiC) ceramic powder as a substrate.
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Establishing a new methodology for determining the water absorbability of cellulose-derived materials via a vapor-monitoring headspace strategy

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02209A, Communication
Yi-Xian Gong, Wei-Qi Xie
In this research, for the first time, we introduce a vapor-monitoring headspace strategy to establish a new methodology for determining the water absorbability of cellulose-derived materials.
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été

Correction: An impedimetric sensor based on molecularly imprinted nanoparticles for the determination of trypsin in artificial matrices – towards point-of-care diagnostics

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY90029D, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Sabrina Di Masi, Marco Costa, Francesco Canfarotta, Antonio Guerreiro, Alicia Hartley, Sergey A. Piletsky, Cosimino Malitesta
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été

An efficient electrochemical sensor based on the Ce-MOF/g-C3N5 composite for the detection of nitrofurazone

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02221H, Paper
Jianxia Gu, Yiqiong Jia, Zhanbin Jin, Tingting Wei, Yongxia Li
The Ce-MOF/g-C3N5 composite was first constructed using a simple reflux method in an oil bath, and the electrochemical sensor fabricated based on this composite shows excellent detection performance in nitrofurazone detection in practical samples.
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été

Dual-mode detection of 2,6-pyridinedicarboxylic acid based on the enhanced peroxidase-like activity and fluorescence property of novel Eu-MOFs

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00331D, Paper
Jintao Yi, Xianqin Han, Jiahao Jian, Yayan Lai, Jun Lu, Lei Peng, Zhongkai Liu, Jun Xue, Hui Zhou, Xun Li
The dual-mode fluorescence and colorimetric detection of 2,6-pyridinedicarboxylic acid (DPA) based on the enhanced peroxidase-like activity and fluorescence property of a novel MOF.
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Near-infrared responsive gold nanorods for highly sensitive colorimetric and photothermal lateral flow immuno-detection of SARS-CoV-2

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00347K, Paper
Xiaohui Liu, Jingwen Li, Kun Wang, Xiang Li, Shenming Wang, Gengchen Guo, Qiaowen Zheng, Maosheng Zhang, Jingbin Zeng
We developed a colorimetric and photothermal dual-mode LFIA platform for sensitive and selective SARS-CoV-2 N protein detection based on gold nanorods.
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été

A Multimode Biosensor Based on Prussian Blue Nanoparticle Loaded with Gold Nanoclusters for the Detection of Aflatoxin B1

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D3AY02330C, Paper
zhaodi Fu, juan Huang, Wei Wei, zhihui Wu, Xingbo Shi
Herein, a novel fluorescent/colorimetric/photothermal biosensor is proposed for aflatoxin B1 (AFB1) detection in food based on Prussian blue nanoparticles (PBNPs) (~50 nm), gold nanocluster (AuNCs) and aptamer (Apt) within three...
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été

Dual-signal detection of tannin acid in red wines based on peroxidase activity carbon dots

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00526K, Paper
Bin Liu, Yu Yin, qianwen Li, wanwan Li, Fubing Xiao, Jinquan Liu, Yan Tan, Shengyuan Yang
Herein, a novel sort of phosphorus and iron-doped carbon dots (P,Fe-CDs) with outstanding peroxidase activity and excellent fluorescence performance was hydrothermally synthesized to colorimetrically and fluorimetrically detect tannic acid (TA)....
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Converging optical and electrochemical detection strategies for multimodal hydrazine sensing: insights into substituent-driven diverse response

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00063C, Paper
Rikitha S. Fernandes, Sahil Deepak Vasistha, Ritesh Kumar Singh, Sanket Goel, Nilanjan Dey
A pair of pyrene-based chalcogen derivatives have been developed, which demonstrate multimodal ratiometric response towards hydrazine.
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été

A novel ratiometric sensor for fluorimetric and visual dual-mode detection of Al3+ in environmental water based on the target-regulated formation of Eu MOFs

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00324A, Paper
Tao-Li Chen, Xiang-Juan Kong, Xin-Xin Dong, Zhi-Jie Mao, Fang-Fang Kong, Qiang Xiao
The illustration of the ratiometric sensor for fluorimetric (A) and visual detection (B) of Al3+.
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été

Layer-by-layer assembly of homopolypeptide polyelectrolytes on asymmetric nanochannels for the detection of nickel ions

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00422A, Paper
Pengrong An, Jincan Yang, Tianming Wang, Saiwen Lu, Dehao Wang, Zhuoyue Wang, Chun-Lin Sun, Chuanguang Qin, Jun Li
We report PA-γ-PGA-modified asymmetric nanochannels that enable ultra-sensitive detection of Ni2+ (limit of detection is 1 × 10−8 M).
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été

LAMP-based hydrogen ion selective electrochemical sensor for highly sensitive detection of Mycoplasma pneumoniae

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00341A, Paper
Huiqing Wang, Yang Li, Lin Tian, Xinyi Li, Qian Gao, Yaru Liu, Cuiping Ma, Qing Wang, Chao Shi
An urgent need for a concise and rapid detection method for Mycoplasma pneumoniae is required due to its severe impact on human’s health. To meet such a need, this study...
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été

Antibody-labeled Gold Nanoparticles Based Resonance Rayleigh Scattering Detection of S100B

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00335G, Paper
tiantian Wang, yonghui Wang, junbo Li
Traumatic brain injury (TBI) is a sudden brain injury due to an external force that causes a large number of deaths and permanent disabilities every year. S100B has been recognized...
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Rapid detection of monkeypox virus and differentiation of West African and Congo Basin strains using endonuclease restriction-mediated real-time PCR-based testing

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00492B, Paper
Juan Zhou, Fei Xiao, Xiaolan Huang, Jin Fu, Nan Jia, Chunrong Sun, Min Chen, Zheng Xu, Hui Huang, Yi Wang
A novel multiplex ET-PCR assay that integrates PCR amplification, restriction endonuclease cleavage and real-time fluorescence detection was devised to diagnose MPXV infection and distinguish the Congo Basin and West Africa MPXV strains.
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été

Ag-coated tetrapod gold nanostars (Au@AgNSs) for acetamiprid determination in tea using SERS combined with microfluidics

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00297K, Paper
Qian Ke, Limei Yin, Heera Jayan, Hesham R. El-Seedi, Xiaobo Zou, Zhiming Guo
The combination of highly sensitive SERS substrate core–shell Au@AgNSs and microfluidic chip featuring four circular split hybrid structures were used for quantitative detection of acetamiprid in tea. The LOD of acetamiprid was 0.048 ng mL−1.
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été

Development of a label-free, sensitive gold nanoparticles-poly (adenine)aptasensing platform for colorimetric determination of aflatoxin B1 in corn

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00605D, Paper
Omid Heydari Shayesteh, Katayoun Derakhshandeh, Akram Ranjbar, Reza Mahjub, Abbas Farmany
In this work, a sensitive colorimetric bioassay method based on poly (adenine) aptamer (polyA apt) and gold nanoparticles (AuNPs) was developed to the determination of aflatoxin B1 (AFB1). The polyA...
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été

A novel fluorescent probe with a large Stokes shift for colorimetric and selective detection of cysteine in water, milk, cucumber, pear and tomato

Anal. Methods, 2024, 16,2322-2329
DOI: 10.1039/D3AY02322B, Paper
Lin Luo, Ranran Guo, Lianjie Wang, Xixi Song, Zhao Wang, Junliang Wu
A novel fluorescent probe for colorimetric and selective detection of cysteine was efficiently constructed through a simple and mild reaction conditions. Probe 2 displays a linear response to Cys concentrations (0–30 μM), low detection limit (0.89 μM), large Stoke shift (125 nm).
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A three-dimensional network structure of metal-based nanozymes for the construction of colorimetric sensors for the detection of antioxidants

Anal. Methods, 2024, 16,2292-2300
DOI: 10.1039/D3AY02199H, Paper
Shuo Qin, Bin Liu, Yuting Xue, Ruixue Zhao, Guo Wang, Kai Li, Lirong Zheng, Pingyang Wang, Tianhao Tang, Yue Yang, Zhengbo Chen, Xia Zuo
Although many excellent nanozymes have been developed, designing and synthesizing highly active nanozymes is still challenging.
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été

Heparin-stabilized gold nanoparticles embedded in graphene for the electrochemical determination of esculetin

Anal. Methods, 2024, 16,2256-2266
DOI: 10.1039/D4AY00229F, Paper
Vinicius José da Silva, Luan Gabriel Baumgarten, Juliana Priscila Dreyer, Edson Roberto Santana, Almir Spinelli, João Paulo Winiarski, Iolanda Cruz Vieira
A conductive nanocomposite consisting of heparin-stabilized gold nanoparticles embedded in graphene was prepared for esculetin determination in tea and jam samples.
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A pH-response-based fluorescent probe for detecting the mitophagy process by tracing changes in colocalization coefficients

Anal. Methods, 2024, 16,2241-2247
DOI: 10.1039/D4AY00211C, Paper
Nongyi Hao, Zekun Jiang, Lina Zhou, Xiaoyu Dai, Xiuqi Kong
A novel pH-response fluorescent probe MP for the detection of mitophagy process via tracing colocalization coeffcients was developed.
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Construction of a stable fluorescent sensor based on CsPbBr3/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol

Anal. Methods, 2024, 16,2267-2277
DOI: 10.1039/D4AY00032C, Paper
Yang He, Yangjie Li, Han Wang, Site Luo, Haihu Yu
Construction of a stable fluorescent sensor based on CsPbBr3/CdS core/shell quantum dots for selective and sensitive detection of tetracycline in ethanol via a mechanism integrating photoinduced electron transfer.
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Phenylboronic acid modification-based novel dumbbell-shaped Au–Ag nanorod SERS substrates for ultrasensitive detection of SO42−

Anal. Methods, 2024, 16,2311-2321
DOI: 10.1039/D3AY01831H, Paper
Kang Shen, Caili Bi, Haifan Yang, Miaowen Xu, Lili Huang, Youwei Wang
Based on the coordination principle of Lewis acids, a novel 4-MPBA-modified dumbbell-shaped Au–Ag nanorod (4-MPBA@DS Au–AgNR) SERS substrate was developed to realize the high sensitivity and specificity of SO42− detection.
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Characterizing a visual lateral flow device for rapid SARS-CoV-2 virus protein detection: pre-clinical and system assessment

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02075D, Paper
Natpapas Wiriyachaiporn, Jetnapang Kongrueng, Kannika Sukkuea, Rattana Tanrattanawong, Jarunee Vanichtanankul, Thanaya Saeyang, Tararat Jantra, Deanpen Japrung, Weerakanya Maneeprakorn, Suwussa Bamrungsap, Pareena Janchompoo, Ekawat Pasomsub
Analytical and pre-clinical evaluation of a visual screening lateral flow device for SARS-CoV-2 virus protein detection and its system characterization.
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été

Construction of coumarin-appended calix[4]arene-based fluorescence sensor for the detection of carbofuran in cabbage

Anal. Methods, 2024, 16,2400-2411
DOI: 10.1039/D4AY00030G, Paper
Heni Soni, Nidhi Verma, Divyesh Y. Chaudhari, Sahaj A. Gandhi, Alok Pandya, Pinkesh G. Sutariya
This study presents a novel approach for the detection of carbofuran (CBF) insecticide by exploring a calix[4]arene-derived fluorescence probe, CouC4S, functionalized with two coumarin-labelled at the narrow edge of the calix[4]arene platform.
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An overview of electrochemical biosensors used for COVID-19 detection

Anal. Methods, 2024, 16,2164-2176
DOI: 10.1039/D3AY02042H, Minireview
Tatiana Lima Valerio, Raquel Anastácio, Stella Schuster da Silva, Carolina Camargo de Oliveira, Marcio Vidotti
This short review presents the latest advances in the field of electrochemical biosensors, focusing particularly on impedimetric biosensors for the direct measurement of analytes.
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A new colorimetric aptasensor for paraquat detection based on the designed aptamer with multiple paraquat binding sites in combination with gold nanoparticles

Anal. Methods, 2024, 16,2340-2348
DOI: 10.1039/D4AY00053F, Paper
Pakawat Kongpreecha, Sineenat Siri
Given paraquat's environmental health risks, there is a need for a fast and simple detection method. This study presents a novel colorimetric aptasensor with a tailored aptamer, boosting sensitivity by targeting multiple paraquat binding sites.
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An immunochromatographic strip sensor for rapid and sensitive detection of candesartan, olmesartan medoxomil, and irbesartan in herbal beverages

Anal. Methods, 2024, 16,2359-2367
DOI: 10.1039/D4AY00151F, Paper
Dingyu Li, Aihong Wu, Liqiang Liu, Hua Kuang, Chuanlai Xu, Xiaoling Wu
Sartans, as a class of antihypertensive drugs, pose a threat to human health when illegally added to herbal beverages.
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Detection of Free DNA Based on Metal-Enhanced Fluorescence Triggered by CRISPR-Cas12a and Colorimetric Analysis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00149D, Paper
Ming-Qiu Zheng, Yuyao Li, Liling Zhang, Cheng-Yu Li, Menghan Liu, Hongwu Tang
The CRISPR-Cas system has been found to be extremely sensitive and there is an urgent demand to extend its potential in bioassay. Herein, we developed a novel nanobiosensor to detect...
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A simple and rapid colorimetric detection of Staphylococcus Aureus relied on the distance-dependent optical properties of silver nanoparticles

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D3AY02189K, Paper
Ngoc Anh Thu Phan, Hoang Men Nguyen, Cam Duyen Thi Vo, Toi Vo Van, Phuoc Long Truong
The quick and accurate diagnosis of pathogens has appeared as a pressing issue in clinical diagnostics, environmental monitoring, and food safety. The current assays are suffering from limited capacities in...
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Paper-based sensors: affordable, versatile, and emerging analyte detection platforms

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02258G, Critical Review
Open Access
Sumit Malik, Joginder Singh, Kajal Saini, Vivek Chaudhary, Ahmad Umar, Ahmed A. Ibrahim, Sheikh Akbar, Sotirios Baskoutas
The schematic representation of distance based paper sensor to identify lead in food samples.
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été

A reaction based carbazole–indolium conjugate probe for the selective detection of environmentally toxic ions

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00301B, Paper
Jayasudha Palanisamy, Mansour K. Gatasheh, Ashraf Atef Hatamleh
Carbazole–indolium based colorimetric probe was designed for detecting cyanide ions in various water samples. An outstanding response was shown by paper test strips prepared using the probe for the easy detection of cyanide in real time.
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été

Polymeric membrane potentiometric sensors based on template-removal-free imprinted receptors for determination of antibiotics

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D4AY00263F, Paper
Xinyao Wang, Guohua Cui, Rongning Liang, Wei Qin
Currently, Nernstian-response-based polymeric membrane potentiometric sensors using the molecularly imprinted polymers (MIPs) as the receptors have been successfully developed for determination of organic ionic species. However, the preparation of these...
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Design and fabrication of La-based perovskites incorporated with functionalized carbon nanofibers for the electrochemical detection of roxarsone in water and food samples

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00264D, Paper
Mariya Antony John Felix, Santhiyagu Sahayaraj Rex Shanlee, Shen-Ming Chen, Sundaresan Ruspika, Ramachandran Balaji, Narendhar Chandrasekar, Periyanayagam Arockia Doss
Fabrication of potent electrocatalyst, La-based perovskites coupled with functionalized carbon nanofibers (LMO/f-CNF) for ultrasensitive electrochemical detection of roxarsone in edible and water samples.
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été

A chemodosimetric chemosensor for the ratiometric detection of nerve agent-mimic DCP in solution and vapor phases

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00451E, Paper
Shilpita Banerjee, Pintu Ghosh, Anirban Karak, Dipanjan Banik, Ajit Kumar Mahapatra
The probe MNFZ undergoes a hydrolysis reaction in the presence of DCP to exhibit a naked eye color change from blue to cyan. It was successfully applied to sense DCP in the vapor phase.
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été

A highly selective probe engineered to detect polarity and distinguish normal cells and tumor cells in tissue sections

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00438H, Paper
Sai Zhu, Lixuan Dai, Xiaoli Zhong, Weiying Lin
We have designed a polarity fluorescent probe (DCI-Cou-polar) with high selectivity for diagnosing cancer.
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été

A colorimetric tandem combination of CRISPR/Cas12a with dual functional hybridization chain reaction for ultra-sensitive detection of mycobacterium bovis

Anal. Methods, 2024, Accepted Manuscript
DOI: 10.1039/D3AY02200E, Paper
Qiong Liu, Mei Yang, He Zhang, Wenjie Ma, Xin Fu, Huiqing Li, Sainan Gao
Tuberculosis caused by Mycobacterium bovis poses a global infectious threat to humans and animals. Therefore, there is an urgent need to develop a sensitive, precise, and easy-to-readout strategy. Here, a...
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Detecting Specific Text Input with HTML and CSS

Recently I came across a CodePen demo by a developer/engineer named Jane that was Tweeted out by Šime Vidas. The demo has a neat collection of HTML and CSS tricks rolled into one that I thought was worth examining in detail.

The page displays a secret message based on specific text input. Ok, that’s no big deal, right? Well this is done using pure HTML and CSS – no JavaScript. I’ve seen stuff like this before, but I thought it would be cool to break down exactly how this works. There are a few notable things happening in the code so I’ll break down each of the parts.

The post Detecting Specific Text Input with HTML and CSS appeared first on Impressive Webs.




été

Design, synthesis, inhibitory activity, and molecular simulations study for D-glucose-conjugated thioureas containing pyrimidine ring as multitarget inhibitors against α-amylase, α-glucosidase, DDP-4, and PTP1B in Type 2 diabetes mellitus

RSC Med. Chem., 2024, 15,3395-3417
DOI: 10.1039/D4MD00334A, Research Article
Vu Ngoc Toan, Do Son Hai, Hoang Thi Kim Van, Nguyen Minh Tri, Duong Ngoc Toan, Nguyen Thi Thanh Mai, Nguyen Dinh Thanh
D-Glucose-conjugated thioureas from 2-aminopyrimidines had inhibitory activity against α-amylase, α-glucosidase, DPP-4, PTP1B. The cytotoxicity, inhibitory kinetics, and molecular simulations of the most potent inhibitors 8k, 8j, 8f, and 8h were studied.
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été

Rational design and in vitro testing of new urease inhibitors to prevent urinary catheter blockage

RSC Med. Chem., 2024, 15,3597-3608
DOI: 10.1039/D4MD00378K, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
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In silico identification of urease inhibitors based on thiourea, tested to determine IC50 and tested on a catheterised in vitro bladder model, showing efficacy in reducing catheter blockage.
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