esea How do we decide? Knowledge? Experience? Research? By feeds.nature.com Published On :: 2020-03-27 Full Article
esea Guidelines and definitions for research on epithelial–mesenchymal transition By feeds.nature.com Published On :: 2020-04-16 Full Article
esea 2020–2021 International Security Program Research Fellowships: Apply Now By feedproxy.google.com Published On :: Jan 9, 2020 Jan 9, 2020The International Security Program (ISP) is still accepting applications for 2020–2021. ISP is a multidisciplinary research group that develops and trains new talent in security studies by hosting pre- and postdoctoral research fellows. Full Article
esea 2020–2021 International Security Program Research Fellowships: Apply Now By feedproxy.google.com Published On :: Jan 9, 2020 Jan 9, 2020The International Security Program (ISP) is still accepting applications for 2020–2021. ISP is a multidisciplinary research group that develops and trains new talent in security studies by hosting pre- and postdoctoral research fellows. Full Article
esea Viral genomics in Ebola virus research By feeds.nature.com Published On :: 2020-05-04 Full Article
esea 2020–2021 International Security Program Research Fellowships: Apply Now By feedproxy.google.com Published On :: Jan 9, 2020 Jan 9, 2020The International Security Program (ISP) is still accepting applications for 2020–2021. ISP is a multidisciplinary research group that develops and trains new talent in security studies by hosting pre- and postdoctoral research fellows. Full Article
esea 2020–2021 International Security Program Research Fellowships: Apply Now By feedproxy.google.com Published On :: Jan 9, 2020 Jan 9, 2020The International Security Program (ISP) is still accepting applications for 2020–2021. ISP is a multidisciplinary research group that develops and trains new talent in security studies by hosting pre- and postdoctoral research fellows. Full Article
esea 2020–2021 International Security Program Research Fellowships: Apply Now By feedproxy.google.com Published On :: Jan 9, 2020 Jan 9, 2020The International Security Program (ISP) is still accepting applications for 2020–2021. ISP is a multidisciplinary research group that develops and trains new talent in security studies by hosting pre- and postdoctoral research fellows. Full Article
esea 2020–2021 International Security Program Research Fellowships: Apply Now By feedproxy.google.com Published On :: Jan 9, 2020 Jan 9, 2020The International Security Program (ISP) is still accepting applications for 2020–2021. ISP is a multidisciplinary research group that develops and trains new talent in security studies by hosting pre- and postdoctoral research fellows. Full Article
esea 2020–2021 International Security Program Research Fellowships: Apply Now By feedproxy.google.com Published On :: Jan 9, 2020 Jan 9, 2020The International Security Program (ISP) is still accepting applications for 2020–2021. ISP is a multidisciplinary research group that develops and trains new talent in security studies by hosting pre- and postdoctoral research fellows. Full Article
esea 2020–2021 International Security Program Research Fellowships: Apply Now By feedproxy.google.com Published On :: Jan 9, 2020 Jan 9, 2020The International Security Program (ISP) is still accepting applications for 2020–2021. ISP is a multidisciplinary research group that develops and trains new talent in security studies by hosting pre- and postdoctoral research fellows. Full Article
esea 2020–2021 International Security Program Research Fellowships: Apply Now By feedproxy.google.com Published On :: Jan 9, 2020 Jan 9, 2020The International Security Program (ISP) is still accepting applications for 2020–2021. ISP is a multidisciplinary research group that develops and trains new talent in security studies by hosting pre- and postdoctoral research fellows. Full Article
esea 2020–2021 International Security Program Research Fellowships: Apply Now By feedproxy.google.com Published On :: Jan 9, 2020 Jan 9, 2020The International Security Program (ISP) is still accepting applications for 2020–2021. ISP is a multidisciplinary research group that develops and trains new talent in security studies by hosting pre- and postdoctoral research fellows. Full Article
esea 2020–2021 International Security Program Research Fellowships: Apply Now By feedproxy.google.com Published On :: Jan 9, 2020 Jan 9, 2020The International Security Program (ISP) is still accepting applications for 2020–2021. ISP is a multidisciplinary research group that develops and trains new talent in security studies by hosting pre- and postdoctoral research fellows. Full Article
esea You Can Never Have Too Much Money, New Research Shows By webfeeds.brookings.edu Published On :: Mon, 29 Apr 2013 00:00:00 -0400 Downloads Download full paper Full Article
esea Passages to India: Reflecting on 50 years of research in South Asia By webfeeds.brookings.edu Published On :: Wed, 18 May 2016 13:30:00 -0400 Editors’ Note: How do states manage their armed forces, domestic politics, and foreign affairs? Stephen Cohen, senior fellow with the India Project at Brookings, has studied this and a range of other issues in Southeast Asia since the 1960s. In a new book, titled “The South Asia Papers: A Critical Anthology of Writings,” Cohen reflects on more than a half-century of scholarship on India, describing the dramatic changes he has personally witnessed in the field of research. The following is an excerpt from the book’s preface. [In the 1960s, questions about how states manage their armed forces] were not only unasked in the South Asian context by scholars; they were also frowned on by the Indian government. This made preparation both interesting and difficult. It was interesting because a burgeoning literature on civil–military relations in non-Western states could be applied to India. Most of it dealt with two themes: the “man on horseback,” or how the military came to power in a large number of new states, and how the military could assist in the developmental process. No one had asked these questions of India, although the first was relevant to Pakistan, then still governed by the Pakistani army in the form of Field Marshal Ayub Khan. *** During my first and second trips [in the 1960s] my research was as a historian, albeit one interested in the army’s social, cultural, and policy dimensions. I discovered, by accident, that this was part of the movement toward the “new military history.” Over the years I have thus interacted with those historians who were interested in Indian military history, including several of my own students. While the standard of historians in India was high in places like the University of Calcutta, military history was a minor field, just as it was in the West. Military historians are often dismissed as the “drums and trumpets” crowd, interested in battles, regiments, and hardware, but not much else. My own self-tutoring in military history uncovered something quite different: a number of scholars, especially sociologists, had written on the social and cultural impact of armed forces, a literature largely ignored by the historians. While none of this group was interested in India, the connection between one of the world’s most complicated and subtle societies, the state’s use of force, and the emergence of a democratic India was self-evident. *** A new generation of scholars and experts, many of them Indians (some trained in the United States) and Indian Americans who have done research in India, have it right: this is a complex civilizational-state with expanding power, and its rise is dependent on its domestic stability, its policies toward neighbors (notably Pakistan), the rise of China, and the policies of the United States. The literature that predicts a conflict between the rising powers (India and China), and between them and America the “hegemon,” is misguided: the existence of nuclear weapons by all three states, plus Pakistan, ensures that barring insanity, any rivalries between rising and established states will be channeled into “ordinary” diplomatic posturing, ruthless economic competition, and the clash of soft power. In this competition, India has some liabilities and many advantages, and the structure of the emerging world suggests a closer relationship between the United States and India, without ruling out much closer ties between China and India. There remain some questions: Can the present Indian leadership show magnanimity in dealing with Pakistan, and does it have the foresight to look ahead to new challenges, notably environmental and energy issues that require new skills and new international arrangements? Importantly, some of the best work on answering these questions is being done in India itself, and the work of Kanti Bajpai, Amitabh Mattoo, Harsh Pant, C. Raja Mohan, Rajesh Basrur, and others reveals the maturity of Indian thinking on strategic issues. It has not come too soon, as the challenges that India will face are growing, and those of Pakistan are even more daunting. Authors Stephen P. Cohen Full Article
esea Hubs of Transformation: Leveraging the Great Lakes Research Complex for Energy Innovation By webfeeds.brookings.edu Published On :: Wed, 02 Jun 2010 14:29:00 -0400 Policy Brief #173 America needs to transform its energy system, and the Great Lakes region (including Minnesota, Wisconsin, Iowa, Missouri, Illinois, Indiana, Ohio, Michigan, Kentucky, West Virginia, western Pennsylvania and western New York) possesses many of the needed innovation assets. For that reason, the federal government should leverage this troubled region’s research and engineering strengths by launching a region-wide network of collaborative, high intensity energy research and innovation centers.Currently, U.S. energy innovation efforts remain insufficient to ensure the development and deployment of clean energy technologies and processes. Such deployment is impeded by multiple market problems that lead private firms to under-invest and to focus on short-term, low-risk research and product development. Federal energy efforts—let alone state and local ones—remain too small and too poorly organized to deliver the needed breakthroughs. A new approach is essential. RECOMMENDATIONS The federal government should systematically accelerate national clean energy innovation by launching a series of “themed” research and commercialization centers strategically situated to draw on the Midwest’s rich complex of strong public universities, national and corporate research laboratories, and top-flight science and engineering talent. Organized around existing capacities in a hub-spoke structure that links fundamental science with innovation and commercialization, these research centers would engage universities, industries and labs to work on specific issues that would enable rapid deployment of new technologies to the marketplace. Along the way, they might well begin to transform a struggling region’s ailing economy. Roughly six compelling innovation centers could reasonably be organized in the Great Lakes states with total annual funding between $1 billion and $2 billion.To achieve this broad goal, the federal government should:Increase energy research funding overall. Adopt more comprehensive approaches to research and development (R&D) that address and link multiple aspects of a specific problem, such as transportation. Leverage existing regional research, workforce, entrepreneurial and industrial assets. America needs to transform its energy system in order to create a more competitive “next economy” that is at once export-oriented, lower-carbon and innovation-driven. Meanwhile, the Great Lakes region possesses what may be the nation’s richest complex of innovation strengths—research universities, national and corporate research labs, and top-flight science and engineering talent. Given those realities, a partnership should be forged between the nation’s needs and a struggling region’s assets.To that end, we propose that the federal government launch a distributed network of federally funded, commercialization-oriented, sustainable energy research and innovation centers, to be located in the Great Lakes region. These regional centers would combine aspects of the “discovery innovation institutes” proposed by the National Academy of Engineering and the Metropolitan Policy Program (as articulated in “Energy Discovery-Innovation Institutes: A Step toward America’s Energy Sustainability”); the “energy innovation hubs” created by the Department of Energy (DOE); and the agricultural experiment station/cooperative extension model of the land-grant universities.In the spirit of the earlier land-grant paradigm, this network would involve the region’s research universities and national labs and engage strong participation by industry, entrepreneurs and investors, as well as by state and local governments. In response to local needs and capacities, each center could have a different theme, though all would conduct the kinds of focused translational research necessary to move fundamental scientific discoveries toward commercialization and deployment.The impact could be transformational. If built out, university-industry-government partnerships would emerge at an unprecedented scale. At a minimum, populating auto country with an array of breakthrough-seeking, high-intensity research centers would stage a useful experiment in linking national leadership and local capacities to lead the region—and the nation—toward a more prosperous future. The Great Lakes Energy System: Predicaments and Possibilities The Great Lakes region lies at the center of the nation’s industrial and energy system trials and possibilities. No region has suffered more from the struggles of America’s manufacturing sector and faltering auto and steel industries, as indicated in a new Metropolitan Policy Program report entitled “The Next Economy: Rebuilding Auto Communities and Older Industrial Metros in the Great Lakes Region.”The region also lies at ground zero of the nation’s need to “green” U.S. industry to boost national economic competitiveness, tackle climate change and improve energy security. Heavily invested in manufacturing metals, chemicals, glass and automobiles, as well as in petroleum refining, the Great Lakes states account for nearly one-third of all U.S. industrial carbon emissions.And yet, the Great Lakes region possesses significant assets and capacities that hold promise for regional renewal as the “next economy” comes into view. The Midwest’s manufacturing communities retain the strong educational and medical institutions, advanced manufacturing prowess, skills base and other assets essential to helping the nation move toward and successfully compete in the 21st century’s export-oriented, lower-carbon, innovation-fueled economy.Most notably, the region has an impressive array of innovation-related strengths in the one field essential to our nation’s future—energy. These include:Recognized leadership in R&D. The Great Lakes region accounts for 33 percent of all academic and 30 percent of all industry R&D performed in the United States. Strength and specialization in energy, science and engineering. In FY 2006, the Department of Energy sent 26 percent of its federal R&D obligations to the Great Lakes states and is the second largest federal funder of industrial R&D in the region. Also in 2006, the National Science Foundation sent 30 percent of its R&D obligations there. Existing clean energy research investments and assets. The University of Illinois is a key research partner in the BP-funded, $500 million Energy Biosciences Institute, which aims to prototype new plants as alternative fuel sources. Toledo already boasts a growing solar industry cluster; Dow Corning’s Michigan facilities produce leading silicon and silicone-based technology innovations; and the Solar Energy Laboratory at the University of Wisconsin-Madison, the oldest of its kind in the world, has significant proficiency in developing practical uses for solar energy. Finally, the region is home to the largest U.S. nuclear utility (Exelon), the nation’s largest concentration of nuclear plants and some of the country’s leading university programs in nuclear engineering. Industry potential relevant to clean energy. Given their existing technological specializations, Midwestern industries have the potential to excel in the research and manufacture of sophisticated components required for clean energy, such as those used in advanced nuclear technologies, precision wind turbines and complex photovoltaics. Breadth in energy innovation endeavors and resources. In addition to universities and industry, the region’s research laboratories specialize in areas of great relevance to our national energy challenges, including the work on energy storage systems and fuel and engine efficiency taking place at Argonne National Laboratory, research in high-energy physics at the Fermi National Accelerator Laboratory, and the work on bioenergy feedstocks, processing technologies and fuels occurring at the DOE-funded Great Lakes BioEnergy Research Center (GLBRC). Regional culture of collaboration. Finally, the universities of the Great Lakes area have a strong history of collaboration both among themselves and with industry, given their origins in the federal land-grant compact of market and social engagement. GLBRC—one of the nation’s three competitively awarded DOE Bioenergy Centers—epitomizes the region’s ability to align academia, industry and government around a single mission. Another example is the NSF-supported Blue Waters Project. This partnership between IBM and the universities and research institutions in the Great Lakes Consortium for Petascale Computation is building the world’s fastest computer for scientific work—a critical tool for advancing smart energy grids and transportation systems.In short, the Great Lakes states and metropolitan areas—economically troubled and carbon-reliant as they are—have capabilities that could contribute to their own transformation and that of the nation, if the right policies and investments were in place.Remaking America’s Energy System within a Federal Policy FrameworkAmerica as a whole, meanwhile, needs to overcome the massive sustainability and security challenges that plague the nation’s energy production and delivery system. Transformational innovation and commercialization will be required to address these challenges and accelerate the process of reducing the economy’s carbon intensity.Despite the urgency of these challenges, however, a welter of market problems currently impedes decarbonization and limits innovation. First, energy prices have generally remained too low to provide incentives for companies to commit to clean and efficient energy technologies and processes over the long haul. Second, many of the benefits of longrange innovative activity accrue to parties other than those who make investments. As a result, individual firms tend to under-invest and to focus on short-term, low-risk research and product development. Third, uncertainty and lack of information about relevant market and policy conditions and the potential benefits of new energy technologies and processes may be further delaying innovation. Fourth, the innovation benefits that derive from geographically clustering related industries (which for many years worked so well for the auto industry) have yet to be fully realized for next-generation energy enterprises. Instead, these innovations often are isolated in secure laboratories. Finally, state and local governments—burdened with budgetary pressures—are not likely to fill gaps in energy innovation investment any time soon.As a result, the research intensity—and so the innovation intensity—of the energy sector remains woefully insufficient, as pointed out in the earlier Metropolitan Policy Program paper on discovery innovation institutes. Currently, the sector devotes no more than 0.3 percent of its revenues to R&D. Such a figure lags far behind the 2.0 percent of sales committed to federal and large industrial R&D found in the health care sector, the 2.4 percent in agriculture, and the 10 percent in the information technology and pharmaceutical industries.As to the national government’s efforts to respond to the nation’s energy research shortfalls, these remain equally inadequate. Three major problems loom:The scale of federal energy research funding is insufficient. To begin with, the current federal appropriation of around $3 billion a year for nondefense energy-related R&D is simply too small. Such a figure remains well below the $8 billion (in real 2008 dollars) recorded in 1980, and represents less than a quarter of the 1980 level when measured as a share of GDP. If the federal government were to fund next-generation energy at the pace it supports advances in health care, national defense, or space exploration, the level of investment would be in the neighborhood of $20 billion to $30 billion a year.Nor do the nation’s recent efforts to catalyze energy innovation appear sufficient. To be sure, the American Recovery and Reinvestment Act (ARRA) provided nearly $13 billion for DOE investments in advanced technology research and innovation. To date, Great Lakes states are slated to receive some 42 percent of all ARRA awards from the fossil energy R&D program and 39 percent from the Office of Science (a basic research agency widely regarded as critical for the nation’s energy future). However, ARRA was a one-time injection of monies that cannot sustain adequate federal energy R&D.Relatedly, the Great Lakes region has done well in tapping two other relatively recent DOE programs: the Advanced Research Projects Agency–Energy (ARPA-E) and Energy Frontier Research Centers (EFRCs). Currently, Great Lakes states account for 44 and 50 percent of ARPA-E and EFRC funding. Yet, with ARPA-E focused solely on individual signature projects and EFRC on basic research, neither initiative has the scope to fully engage all of the region's innovation assets.The character and format of federal energy R&D remain inadequate. Notwithstanding the question of scale, the character of U.S. energy innovation also remains inadequate. In this respect, the DOE national laboratories—which anchor the nation’s present energy research efforts—are poorly utilized resources. Many of these laboratories’ activities are fragmented and isolated from the private sector and its market, legal and social realities. This prevents them from successfully developing and deploying cost-competitive, multidisciplinary new energy technologies that can be easily adopted on a large scale.For example, DOE activities continue to focus on discrete fuel sources (such as coal, oil, gas or nuclear), rather than on fully integrated end use approaches needed to realize affordable, reliable, sustainable energy. Siloed approaches simply do not work well when it comes to tackling the complexity of the nation’s real-world energy challenges. A perfect example of a complicated energy problem requiring an integrated end-use approach is transportation. Moving the nation’s transportation industry toward a clean energy infrastructure will require a multi-pronged, full systems approach. It will depend not only upon R&D in such technologies as alternative propulsion (biofuels, hydrogen, electrification) and vehicle design (power trains, robust materials, advanced computer controls) but also on far broader technology development, including that related to primary energy sources, electricity generation and transmission, and energy-efficient applications that ultimately will determine the economic viability of this important industry.Federal programming fails to fully realize regional potential. Related to the structural problems of U.S. energy innovation efforts, finally, is a failure to fully tap or leverage critical preexisting assets within regions that could accelerate technology development and deployment. In the Great Lakes, for example, current federal policy does little to tie together the billions of dollars in science and engineering R&D conducted or available annually. This wealth is produced by the region’s academic institutions, all of the available private- and public-sector clean energy activities and financing, abundant natural resources in wind and biomass, and robust, pre-existing industrial platforms for research, next-generation manufacturing, and technology adoption and deployment. In this region and elsewhere, federal policy has yet to effectively connect researchers at different organizations, break down stovepipes between research and industry, bridge the commercialization “valley of death,” or establish mechanisms to bring federally-sponsored R&D to the marketplace quickly and smoothly.A New Approach to Regional, Federally Supported Energy Research and Innovation And so the federal government should systematically accelerate clean energy innovation by launching a series of regionally based Great Lakes research centers. Originally introduced in the Metropolitan Policy Program policy proposal for energy discovery-innovation institutes (or e-DIIs), a nationwide network of regional centers would link universities, research laboratories and industry to conduct translational R&D that at once addresses national energy sustainability priorities, while stimulating regional economies.In the Great Lakes, specifically, a federal effort to “flood the zone” with a series of roughly six of these high-powered, market-focused energy centers would create a critical mass of innovation through their number, size, variety, linkages and orientation to pre-existing research institutions and industry clusters.As envisioned here, the Great Lakes network of energy research centers would organize individual centers around themes largely determined by the private market. Based on local industry research priorities, university capabilities and the market and commercialization dynamics of various technologies, each Great Lakes research and innovation center would focus on a different problem, such as renewable energy technologies, biofuels, transportation energy, carbon-free electrical power generation, and distribution and energy efficiency. This network would accomplish several goals at once:Foster multidisciplinary and collaborative research partnerships. The regional centers or institutes would align the nonlinear flow of knowledge and activity across science and non-science disciplines and among companies, entrepreneurs, commercialization specialists and investors, as well as government agencies (federal, state and local) and research universities. For example, a southeastern Michigan collaboration involving the University of Michigan, Michigan State University, the University of Wisconsin and Ford, General Motors, and Dow Chemical could address the development of sustainable transportation technologies. A Chicago partnership involving Northwestern and Purdue Universities, the University of Chicago, the University of Illinois, Argonne National Lab, Exelon and Boeing could focus on sustainable electricity generation and distribution. A Columbus group including Ohio State University and Battelle Memorial Institute could address technologies for energy efficiency. Regional industry representatives would be involved from the earliest stages to define needed research, so that technology advances are relevant and any ensuing commercialization process is as successful as possible. Serve as a distributed “hub-spoke” network linking together campus-based, industry-based and federal laboratory-based scientists and engineers. The central “hubs” would interact with other R&D programs, centers and facilities (the “spokes”) through exchanges of participants, meetings and workshops, and advanced information and communications technology. The goals would be to limit unnecessary duplication of effort and cumbersome management bureaucracy and to enhance the coordinated pursuit of larger national goals. Develop and rapidly deploy highly innovative technologies to the market. Rather than aim for revenue maximization through technology transfer, the regional energy centers would be structured to maximize the volume, speed and positive societal impact of commercialization. As much as possible, the centers would work out in advance patenting and licensing rights and other intellectual property issues.Stimulate regional economic development. Like academic medical centers and agricultural experiment stations—both of which combine research, education and professional practice—these energy centers could facilitate cross-sector knowledge spillovers and innovation exchange and propel technology transfer to support clusters of start-up firms, private research organizations, suppliers, and other complementary groups and businesses—the true regional seedbeds of greater economic productivity, competitiveness and job creation. Build the knowledge base necessary to address the nation’s energy challenges. The regional centers would collaborate with K-12 schools, community colleges, regional universities, and workplace training initiatives to educate future scientists, engineers, innovators, and entrepreneurs and to motivate the region’s graduating students to contribute to the region’s emerging green economy. Complement efforts at universities and across the DOE innovation infrastructure, but be organizationally and managerially separate from either group. The regional energy centers would focus rather heavily on commercialization and deployment, adopting a collaborative translational research paradigm. Within DOE, the centers would occupy a special niche for bottom-up translational research in a suite of new, largely top-down innovation-oriented programs that aim to advance fundamental science (EFRCs), bring energy R&D to scale (Energy Innovation Hubs) and find ways to break the cost barriers of new technology (ARPA-E).To establish and build out the institute network across the Great Lakes region, the new regional energy initiative would:Utilize a tiered organization and management structure. Each regional center would have a strong external advisory board representing the participating partners. In some cases, partners might play direct management roles with executive authority. Adopt a competitive award process with specific selection criteria. Centers would receive support through a competitive award process, with proposals evaluated by an interagency panel of peer reviewers. Receive as much federal funding as major DOE labs outside the Great Lakes region. Given the massive responsibilities of the proposed Great Lakes energy research centers, total federal funding for the whole network should be comparable to that of comprehensive DOE labs, such as Los Alamos, Oak Ridge and others, which have FY2010 budgets between $1 and $2 billion. Based on existing industry-university concentrations, one can envision as many as six compelling research centers in the Great Lakes region.Conclusion In sum, America’s national energy infrastructure—based primarily upon fossil fuels—must be updated and replaced with new technologies. At the same time, no region in the nation is better equipped to deliver the necessary innovations than is the Great Lakes area. And so this strong need and this existing capacity should be joined through an aggressive initiative to build a network of regional energy research and innovation centers. Through this intervention, the federal government could catalyze a dynamic new partnership of Midwestern businesses, research universities, federal laboratories, entrepreneurs and state and local governments to transform the nation’s carbon dependent economy, while renewing a flagging regional economy. Downloads Download Policy Brief Video Research Strength in the Great LakesPursuing Large Scale Innovation Authors James J. DuderstadtMark MuroSarah Rahman Full Article
esea Improving productivity in pharmaceutical research and development By webfeeds.brookings.edu Published On :: Tue, 28 Jul 2015 08:30:00 -0400 Event Information July 28, 20158:30 AM - 5:00 PM EDTAmbassador Ball RoomEmbassy Row Hotel2015 Massachusetts AvenueWashington, DC 20036 Register for the EventThe role of clinical pharmacology and experimental medicine The high failure rate of investigational compounds during drug development, especially in late stages of the clinical development process, is widely seen as a key contributor to the outsize amount of time and resources necessary to develop new drugs. Advances in clinical pharmacology and experimental medicine have the potential to rebalance these trends by providing researchers with the tools to more efficiently and systematically identify promising targets and compounds, appropriate patient populations, and adequate doses for study much earlier in development. On July 28, the Center for Health Policy at Brookings, in collaboration with the International Consortium for Innovation & Quality in Pharmaceutical Development and the U.S. Food and Drug Administration (FDA), hosted a public meeting to tackle these issues. Through presentations and case studies, leading experts from industry, academia, and government agencies explored the evolving role of clinical pharmacology tools in pre-clinical and clinical development, existing gaps in the application of those tools, and how emerging science could be better leveraged to improve the efficiency of drug development programs and better optimize treatments. Discussion at this event will potentially be harnessed to inform downstream guidance documents, to establish best practices for the application of emerging clinical pharmacology tools, or to support academic publications. Speakers will convene privately to discuss such downstream deliverables and key takeaways from the conference. Click here to access the full event agenda. Video Introductory keynotes: Framing the issuesOptimizing target and compound selection to enhance early stage decision-makingThe right dose for the right patient: Challenges and opportunities in dose optimizationPrecision medicine: Trial enrichment, biomarker science, and mechanistic reasoning to optimize patient selectionApplications of clinical pharmacology to support demonstration of efficacy Event Materials Event Slide DeckClinical Pharmacology Public ConferenceClinical Pharmacology BackgrounderClinical Pharmacology Private Roundtable Full Article
esea Learning First: A Research Agenda for Improving Learning in Low-Income Countries By webfeeds.brookings.edu Published On :: Mon, 03 Dec 2012 16:27:00 -0500 EXECUTIVE SUMMARY Parents, educators, government ministers and policymakers in all contexts and countries around the world are concerned with learning and how to improve it. There are many reasons for this, but none is more important than the fact that learning is at the heart of success at the individual, community and global levels. Learning First is the title of this report, with the strong implication that learning should be the foremost goal of education policies worldwide. The present review seeks not only to explain why this is the case but also focuses on what we need to know—that is, what research is needed—in order to improve learning in the decades to come, particularly among those children most in need. This question is addressed in the following six sections. Learning Goals and Research. The first section begins with a historical synopsis of international education goals put forward in 1990 at the World Conference on Education for All in Jomtien (Thailand), in 2000 at the Education for All conference in Dakar, and later in 2000 as a part of the UN Millennium Development Goals for 2015. In 2011, the Center for Universal Education at the Brookings Institution published A Global Compact on Learning: Taking Action on Education in Developing Countries, which stated that there is a “global learning crisis—which affects children and youth who are out of school with limited learning opportunities and those who are in school but not learning the skills they need for their futures.” The present review of learning research in low-income countries follows from that report. The overall purpose is to explore the most pressing learning issues today that require further research attention in the years to come. Learning Definitions and Contexts. This section reviews how the field of education has defined learning over the years. Here, learning is defined as a modification of behavior due to experience—such as in knowledge, skills, attitudes and values. Three main principles of effective learning are suggested: individual active involvement, social participation, and meaningful engagement. As a way to emphasize the importance of learning contexts, three individual stories—Illa, a four-year-old Quechua-speaking girl in Peru; Pawan, an eight-year-old primary school student in urban India; and Rachida, a young illiterate woman in rural Morocco—are provided in order to better explain the importance of learning as a culturally specific phenomenon. These stories help to illustrate a more general learning framework, encompassing the relationship between two dimensions of learning—its processes and contexts. A discussion follows concerning the need to disaggregate learners and their learning contexts—between countries and within countries—as a way to overcome frequent and simplistic generalizations about how the “average” child learns. Global Change and the Contexts of Learning. This section considers the issue of global change on how learning and learning contexts are being transformed around the world. For example, researchers need to pay more attention to the impact of migration on children’s learning and on educational systems more broadly. In each instance of translocation, children confront the challenges of adapting to a new environment that may include different languages, dialects or cultures within the nonformal learning contexts of daily life. Similarly, in formal education contexts, student migrants have to cope with contrasts in culture, lifestyle and language of schooling, and demonstrate skills and achievement that may vary dramatically with their culture of origin. Other changes due to globalization include increased multilingualism in schools, growing overcrowding in classrooms, inability to keep up with teacher training, changes in intergenerational learning, and the growing importance of 21st-century skills. Based on these observations, it is suggested that learning contexts and needs should be understood as a shifting target. Downloads Download the full paper Authors Daniel A. WagnerKatie M. MurphyHaley De Korne Image Source: © Soe Zeya Tun / Reuters Full Article
esea New BPEA Research on Partisanship, Poverty, Unemployment, Homebuyer Perceptions and Capital Controls By webfeeds.brookings.edu Published On :: Thu, 13 Sep 2012 00:00:00 -0400 BPEA co-editor Justin Wolfers describes new research that found: people dropped out of the labor force before the recession started; there are better ways to forecast unemployment; homebuyer expectations helped inflate the bubble; the U.S. is not actually as politically polarized as most people think; central banks’ recent experiments with capital controls haven’t delivered results; and the U.S. is making inroads fighting poverty. Video U.S. Not Actually as Politically Polarized as Most ThinkPoverty Has Fallen Much More than Previously ThoughtNew Unemployment Model Can Outperform ForecastersPerceptions Matter: Homebuyer Expectations Helped Inflate BubbleCentral Banks’ Recent Experiments with Capital Controls Haven’t Delivered Results Authors Justin Wolfers Full Article
esea You Can Never Have Too Much Money, New Research Shows By webfeeds.brookings.edu Published On :: Mon, 29 Apr 2013 00:00:00 -0400 Downloads Download full paper Full Article
esea Addressing the Global Learning Crisis: Lessons from Research on What Works in Education By webfeeds.brookings.edu Published On :: Fri, 27 Jan 2012 09:00:00 -0500 Event Information January 27, 20129:00 AM - 12:30 PM ESTStein RoomThe Brookings Institution1775 Massachusetts Avenue, N.W.Washington, DC 20036 Register for the EventDespite the notable success in enrolling children in primary school over the past decade, the education agenda is unfinished as millions of children are still excluded from learning opportunities and millions more leave school without having acquired the essential knowledge and skills needed to participate in society.On January 27, the Center for Universal Education at Brookings hosted a half-day conference that focused on the research examining “what works in education” to achieve improved learning opportunities and outcomes. In addition to hearing from researchers studying the effectiveness of various education strategies, participants discussed how to facilitate a future research agenda that could have the most meaningful impact on learning. Senior Fellow Jacques van der Gaag moderated the discussion. View the full event summary » Transcript Improving Education in the Developing World: Evidence from Randomized Evaluations Presentation (.pdf)Sociocultural Gradients for Language Scores by Country Slide (.pdf)School Resources and Educational Outcomes in Developing Countries Presentation (.pdf)Making Learning for All a Reality Presentation (.pdf)Addressing the Global Learning Crisis Presentation (.pdf) Event Materials 0127_improving_education_in_developing_world0127_slide_vandergaag0127_edinptoh0127_king0127_wagner Full Article
esea DOE’s justification for rescinding Gainful Employment rules distorts research By webfeeds.brookings.edu Published On :: Mon, 08 Jul 2019 14:09:47 +0000 The Department of Education has rescinded the Gainful Employment regulations developed by the Obama administration. These regulations were designed to cut off federal student aid to postsecondary programs that produce earnings too low to support the debt students incur while earning credentials that promise to lead to good jobs. This action is a significant step… Full Article
esea Rare Swan 'Divorce' Puzzles Researchers By www.treehugger.com Published On :: Sun, 24 Jan 2010 21:55:27 -0500 Once thought of as pillars of monogamy in the animal kingdom, it appears the flame of love can burn out for swans as well. For the first time in 40 years, after following some 4 thousand swans at a reserve in the UK, researchers discovered one formerly Full Article Science
esea New Research Shows Baltimore Heatwave Was Worsened by DC's Hot Air By www.treehugger.com Published On :: Mon, 28 Dec 2009 12:12:54 -0500 In July of 2007, the East Coast was slammed by a record-setting heat wave. From New York City to Washington, DC, temperatures averaged above 90 degrees Fahrenheit, causing more than 40 deaths. Full Article Technology
esea First-Ever Geoengineering Research Ban Considered by Convention on Biological Diversity By www.treehugger.com Published On :: Wed, 20 Oct 2010 12:05:00 -0400 While preservation of the planet's dwindling biodiversity itself has rightly grabbed the headlines at the ongoing Convention on Biological Diversity in Japan, Science Insider points out an important geoengineering Full Article Science
esea Researchers Use Rust and Water to Store Solar Energy as Hydrogen By www.treehugger.com Published On :: Mon, 12 Nov 2012 11:31:43 -0500 Researchers have used abundant and inexpensive materials to create a tandem solar cell that can store solar energy as hydrogen for use at any time of day. Full Article Technology
esea Researchers discover way to produce hydrogen fuel from any plant By www.treehugger.com Published On :: Wed, 10 Apr 2013 08:00:00 -0400 Virginia Tech researchers figure out how to extract large quantities of hydrogen from any plant which could drive down fuel cell costs. Full Article Technology
esea From toilet to table: Peecycling research at U of M investigates urine as fertilizer By www.treehugger.com Published On :: Wed, 29 Apr 2015 16:09:30 -0400 Could human urine be used on a commercial scale to fertilize the food we eat? Full Article Science
esea Researchers at Texas A&M develop a bossy and nosy standing desk By www.treehugger.com Published On :: Thu, 09 Feb 2017 10:57:48 -0500 It tells you when to get up and to sit down, and checks up on you too. Full Article Design
esea Researchers say they're close to a finger swipe-powered phone By www.treehugger.com Published On :: Mon, 12 Dec 2016 11:03:10 -0500 Forget plugging in your phone to charge, soon the battery could stay topped off from swipes and typing. Full Article Technology
esea Researchers in Fiji Say Eating Less Fish Helps Coral Reefs By www.treehugger.com Published On :: Tue, 25 Nov 2008 08:35:00 -0500 As reported in the Otago Daily Times, the noticeable impacts of climate change on area coral reefs and a recent starfish outbreak are not as bad as previously thought due to noticeable changes in the Fijian lifestyle. From Full Article Business
esea Honeybee waggle dance tells researchers about the health of the ecosystem (Video) By www.treehugger.com Published On :: Tue, 27 May 2014 17:40:00 -0400 Honeybees survey vast tracts of land during their communal foraging. They share their best finds in a waggle dance, which new research has turned into a powerful tool for assessing ecosystem health. Full Article Science
esea Yeti robot scans polar ice to warn researchers of dangerous crevasses By www.treehugger.com Published On :: Mon, 02 Sep 2013 07:00:00 -0400 The autonomous robot allows scientists to more safely study polar enviroments and also collects valuable information on ice conditions for climate research. Full Article Technology
esea African grey parrots surprise researchers with their altruism By www.treehugger.com Published On :: Fri, 10 Jan 2020 09:18:33 -0500 Few other animals are known to be intrinsically motivated to assist others in need. Full Article Science
esea Could These Spider-Like, Human-Sized Webs Refine Rainforest Research? By www.treehugger.com Published On :: Fri, 03 Aug 2012 08:00:00 -0400 This project learns from spiders by envisioning a series of interconnected webs that would allow scientists to study the rainforest without harming it. Full Article Design
esea Researchers produce electricity with paper, tape and a pencil By www.treehugger.com Published On :: Tue, 26 Jan 2016 10:37:09 -0500 The device made from household objects could replace AA batteries for powering small electronics. Full Article Technology
esea Researchers Develop Chlorine-Tolerant Membrane for Easy Desalination By www.treehugger.com Published On :: Wed, 30 Jul 2008 19:50:00 -0400 Record droughts, falling water tables and the rapid depletion of aquifers have helped make desalination, a process once considered impractical and too expensive, a viable technology -- at least in some places. As such, there has been a rash of stories -- Full Article Technology
esea New forest research project works to conserve caribou in western Alberta By www.treehugger.com Published On :: Tue, 11 Sep 2018 10:16:19 -0400 Woodland caribou are an iconic but threatened species throughout Canada. They’re natural prey to bears and wolves, who can gain easier access to Caribou habitat through forest roads, pipelines, and other human disturbances. Full Article Business
esea Research From Robert Half, FEI Examines Trends, Reveals Standards in Finance and Accounting - Benchmarking the Accounting & Finance Function: 2014 By feedproxy.google.com Published On :: 13 May 2014 12:08:00 EDT Benchmarking the Accounting & Finance Function: 2014 Full Article Banking Financial Services Workforce Management Human Resources Broadcast Feed Announcements Survey Polls & Research MultiVu Video
esea CEB Research Identifies Ways to Boost Employee Performance - Human Resources By feedproxy.google.com Published On :: 27 Jan 2015 11:20:00 EST Human Resources Full Article Banking Financial Services Workforce Management Human Resources Economic news trends analysis Broadcast Feed Announcements Survey Polls & Research MultiVu Video
esea St. Jude Children's Research Hospital® to honor legendary Hispanic TV personality Cristina Saralegui at upcoming FedEx/St. Jude Angels and Stars Gala - Celeb Gala B-roll By feedproxy.google.com Published On :: 02 May 2016 13:25:00 EDT Miami Gala celebrity B-roll for download Full Article Entertainment Healthcare Hospitals Television Hispanic-oriented News Children-related News Broadcast Feed Announcements MultiVu Video
esea Changing the Research Paradigm with a Patient-Powered Network - CCFA Partners: A patient-powered research network By feedproxy.google.com Published On :: 19 Feb 2015 16:10:00 EST CCFA Partners is an innovative network where patients and researchers work together. Become a part of groundbreaking research: www.ccfapartners.org. Full Article Healthcare Hospitals Medical Pharmaceuticals Higher Education Broadcast Feed Announcements Survey Polls & Research MultiVu Video
esea Cancer Research Funded by The Leukemia & Lymphoma Society Featured in New PBS Documentary Series - Someday Is Today By feedproxy.google.com Published On :: 23 Feb 2015 11:00:00 EST The Leukemia & Lymphoma Society exists to find cures and ensure access to treatments for blood cancer patients. We are saving lives not someday, but today. Full Article Healthcare Hospitals Medical Pharmaceuticals Publishing Information Services Television Broadcast Feed Announcements MultiVu Video
esea Lund University Research Shows a Patented Spinach Extract is Tied To Weight Loss - Spinach extract for losing weight? By feedproxy.google.com Published On :: 28 Apr 2015 16:25:00 EDT Spinach extract for losing weight? Full Article Food Beverages Healthcare Hospitals Supplementary Medicine Broadcast Feed Announcements Survey Polls & Research MultiVu Video
esea L'Oreal Paris and Melanoma Research Alliance (MRA) Unveil It's THAT Worth It To Me, a Public Health Campaign and Social Media Call-to-Action that Drives Melanoma Awareness, Raises Funding for Research and Encourages Sun Protection and Sunless Tann By feedproxy.google.com Published On :: 04 May 2015 20:50:00 EDT Eva Longoria :30 English Full Article Healthcare Hospitals Retail Cosmetics & Personal Care New Products Services Broadcast Feed Announcements MultiVu Video
esea #pass4prostate Challenge Raises Prostate Cancer Awareness and Research Funds - Nick Cummins promotes #pass4prostate By feedproxy.google.com Published On :: 06 Aug 2015 10:50:00 EDT Qantas Wallabies player Nick Cummins promotes the #pass4prostate challenge and USA vs. Australia match coming up on Sept. 5 in Chicago. #pass4prostate and the match are presented by Astellas Pharma Full Article Healthcare Hospitals Internet Technology Medical Pharmaceuticals Sports Social Media Broadcast Feed Announcements Corporate Social Responsibility MultiVu Video
esea American Association for Cancer Research National Survey Shows 74 Percent of Voters Want More Federal Funding for Cancer Research - AACR Survey and Cancer Progress Report 2015 Video By feedproxy.google.com Published On :: 16 Sep 2015 17:15:00 EDT AACR Survey and Cancer Progress Report 2015 Video Full Article Healthcare Hospitals Medical Pharmaceuticals Broadcast Feed Announcements Survey Polls & Research Domestic Policy MultiVu Video
esea The Leukemia & Lymphoma Society Commits $28.6 Million to New Cancer Research Funding - Dr. David Weinstock, Dana-Farber By feedproxy.google.com Published On :: 30 Sep 2015 14:45:00 EDT Dr. David Weinstock of Dana-Farber Cancer Institute discusses his LLS grant Full Article Biotechnology Education Healthcare Hospitals Medical Pharmaceuticals Higher Education Pharmaceuticals Financing Agreements Not for Profit MultiVu Video