“With this expansion, we are excited to connect with even more individuals and families, offering them a curated selection of products that inspire creativity and enrich everyday life," said Divyanshu Solanki, founder and CEO of the company.

My "new" band The Coffee Sergeants. The first single off our new album, Racing Shadows.

So whew, it's been a while! I have been busy with gigs, and stuff, and Carbon 7 is no more, and -- I joined this already-existing band (longtime good friends) 2.5 years ago, and it took us a year to put together enough songs for an album, then another year to get it recorded, mixed and pressed. It's at all the usual online outlets. I borrowed a Rickenbacker 4001 for this song because it just seemed to need it. Yes, it's all the notes all the time. Most of our stuff isn't this frenetic, as you'll see in coming weeks. Carey writes and sings, but he lets the rest of us do our things, so the arrangements are collaborative. Guitars, bass & drums are live & unedited, take two. Keys and vox overdubbed because of bleed.

Glenn Fleishman returns to the show to talk about Elon Musk’s impending acquisition of Twitter, Apple’s credibility problem when arguing against being required to allow sideloading on iOS, and Glenn’s new (and much-needed) book, “Take Control of Untangling Connections”.

Afgelopen jaar vierden we de 20ste verjaardag van de PlayStation. Velen gingen het Japanse bedrijf voor en faalden na hun eerste console uit te hebben gebracht… Waar ging het mis? Betere vraag: waar ging het bij Sony juist wel goed?

Playing video games has long been a challenge for many people with disabilities, since the traditional controllers for the PlayStation, Xbox or Nintendo can be difficult or even impossible to maneuver when a person has limited mobility. Losing the ability to play doesn’t just mean the loss of a favorite pastime — it can also exacerbate social isolation for a community that already experiences it at far higher rates than the general population. Sony’s new Access Controller, developed with input from accessibility consultants, aims to change that.

78 solar panels have been installed at the City of Hamilton’s Front Street pump station which is anticipated to “save the City more than $30,000 a year on electricity costs.” A spokesperson said, “This month the City of Hamilton oversaw the installation of 78 solar panels at its Front Street pump station which, it is […]

The Stationery Store partnered with 15-year-old local artist Nico Bean to launch a new collection of custom notebooks just in time for the back-to-school season. A spokesperson said, “As students gear up for the new school year, the Stationery Store is excited to announce a special partnership with 15-year-old local artist Nico Bean on his […]

“The OBA maintains that the current polling station is not a neutral venue, given the connection found to exist with the PLP candidate,” the OBA Leader said today. Opposition Leader Jarion Richardson said, “Today the Bermuda Court found that the PLP candidate for the Sandys North bye election has a connection to the polling station. […]

Police are investigating an armed robbery that occurred at Robinson’s Marina in Somerset this morning [Oct 24], where a suspect “brandishing a machete, entered the service station and demanded money.” A police spokesperson said, “Shortly after 6:30 a.m. on Thursday, October 24, 2024, police received a report of a robbery at the service station located […]

Death Stranding Director’s Cut - PlayStation 5 $10.00

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Title says it all

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PlayStation $100 GC $90 w/coupon: FTTCX9645

Xbox $100 GC $88 w/coupon: FTTCX9426

Nintendo $50 GC $45 w/coupong: FTTCX9425

Sonic MotherBoard $189.99

All Gaming items at Fantastech Sale

Everything at NewEgg's Fantastech Sale

The post Hydro-Electric Power Station In a Freezing Cold Place of Russia appeared first on English Russia.

Archaeologists are working to understand how astronauts really use their space on the ISS—and help improve space habitats of the future.

An anonymous reader quotes a report from BleepingComputer: VMware has announced that its VMware Fusion and VMware Workstation desktop hypervisors are now free to everyone for commercial, educational, and personal use. In May, the company also made VMware Workstation Pro and Fusion Pro free for personal use, allowing students and home users to set up virtualized test labs and experiment with other OSs by running virtual machines and Kubernetes clusters on Windows, Linux, and macOS devices. Starting this week, the Pro versions and the two products will no longer be available under a paid subscription model. "Effective immediately, both VMware Fusion and VMware Workstation will transition away from the paid subscription model, meaning you can now utilize these tools without any cost. The paid versions of these offerings -- Workstation Pro and Fusion Pro -- are no longer available for purchase," said Broadcom product marketing director Himanshu Singh. "If you're currently under a commercial contract, you can rest easy knowing that your agreement will remain in effect until the end of your term. You will continue to receive the full level of service and enterprise-grade support as per your contract." While the free versions will include all the features available in the paid products, Broadcom will no longer provide users with support ticketing for troubleshooting. Broadcom plans to continue developing new features and improvements and ensure that updates are rolled out promptly. "We're actively investing in new features, usability improvements, and other valuable enhancements," Singh added. "Our engineering teams are committed to maintaining our high standards for stability, with timely updates and reliable performance." You can download VMware Fusion and VMware Workstation here (sign-in required).

Read more of this story at Slashdot.

India has built a 3km-long runway on Agalega and no-one has fully explained why, angering residents.

Satellite images and on-the-ground photos show the scale of destruction caused by the floods.

It was inevitable that a big streamer like Showmax would use the story of the Station Strangler for a 99-minute standalone documentary.

The PlayStation 5 Pro hits shops on Thursday with a price tag that has raised eyebrows among gamers, but growing sticker shocks in the tech industry have yet to deter consumers.

Expert

Africa Aware: Supply chains, land contestation, conflict Audio NCapeling 30 March 2023

This episode examines relations between Ethiopia and Sudan as part of an XCEPT project mini-series.

The war in northern Ethiopia since November 2020, and subsequent conquest of disputed farmlands in Al-Fashaga by the Sudanese army on the Ethiopia-Sudan border, has brought into focus the importance of agricultural commodities such as sesame as a potential driver of land contestation and conflict. 

The panel discusses the interrelation of commodity and conflict supply chains, land contestation, and boundary disputes in the Horn of Africa, with a particular focus on the regions of Wolkait/Western Tigray in northwest Ethiopia and Al Fashaga in eastern Sudan.

This podcast was produced with support from the Cross-Border Conflict Evidence, Policy and Trends (XCEPT) project, funded by UK Aid from the UK government.

Mutations in the GUCY2D gene coding for the dimeric human retinal membrane guanylyl cyclase (RetGC) isozyme RetGC1 cause various forms of blindness, ranging from rod dysfunction to rod and cone degeneration. We tested how the mutations causing recessive congenital stationary night blindness (CSNB), recessive Leber's congenital amaurosis (LCA1), and dominant cone–rod dystrophy-6 (CORD6) affected RetGC1 activity and regulation by RetGC-activating proteins (GCAPs) and retinal degeneration-3 protein (RD3). CSNB mutations R666W, R761W, and L911F, as well as LCA1 mutations R768W and G982VfsX39, disabled RetGC1 activation by human GCAP1, -2, and -3. The R666W and R761W substitutions compromised binding of GCAP1 with RetGC1 in HEK293 cells. In contrast, G982VfsX39 and L911F RetGC1 retained the ability to bind GCAP1 in cyto but failed to effectively bind RD3. R768W RetGC1 did not bind either GCAP1 or RD3. The co-expression of GUCY2D allelic combinations linked to CSNB did not restore RetGC1 activity in vitro. The CORD6 mutation R838S in the RetGC1 dimerization domain strongly dominated the Ca2+ sensitivity of cyclase regulation by GCAP1 in RetGC1 heterodimer produced by co-expression of WT and the R838S subunits. It required higher Ca2+ concentrations to decelerate GCAP-activated RetGC1 heterodimer—6-fold higher than WT and 2-fold higher than the Ser838-harboring homodimer. The heterodimer was also more resistant than homodimers to inhibition by RD3. The observed biochemical changes can explain the dominant CORD6 blindness and recessive LCA1 blindness, both of which affect rods and cones, but they cannot explain the selective loss of rod function in recessive CSNB.

Voltage-gated Cav1 and Cav2 Ca2+ channels are comprised of a pore-forming α1 subunit (Cav1.1-1.4, Cav2.1-2.3) and auxiliary β (β1-4) and α2δ (α2δ−1−4) subunits. The properties of these channels vary with distinct combinations of Cav subunits and alternative splicing of the encoding transcripts. Therefore, the impact of disease-causing mutations affecting these channels may depend on the identities of Cav subunits and splice variants. Here, we analyzed the effects of a congenital stationary night blindness type 2 (CSNB2)-causing mutation, I745T (IT), in Cav1.4 channels typical of those in human retina: Cav1.4 splice variants with or without exon 47 (Cav1.4+ex47 and Cav1.4Δex47, respectively), and the auxiliary subunits, β2X13 and α2δ-4. We find that IT caused both Cav1.4 splice variants to activate at significantly more negative voltages and with slower deactivation kinetics than the corresponding WT channels. These effects of the IT mutation, along with unexpected alterations in ion selectivity, were generally larger in channels lacking exon 47. The weaker ion selectivity caused by IT led to hyperpolarizing shifts in the reversal potential and large outward currents that were evident in channels containing the auxiliary subunits β2X13 and α2δ-4 but not in those with β2A and α2δ-1. We conclude that the IT mutation stabilizes channel opening and alters ion selectivity of Cav1.4 in a manner that is strengthened by exclusion of exon 47 and inclusion of β2X13 and α2δ-4. Our results reveal complex actions of IT in modifying the properties of Cav1.4 channels, which may influence the pathological consequences of this mutation in retinal photoreceptors.

Tianeptine, an addictive drug at high doses, is being sold as a dietary supplement in gas stations and convenient stores. But such products could be contaminated with metals, microorganisms or other undisclosed drugs

An unnamed astronaut was released from Ascension Sacred Heart Pensacola in Florida and returned to Johnson Space Center in Houston in good health Saturday, NASA reported.

A new trio of Chinese astronauts reached the Tiangong space station on Wednesday, starting a handover from the current crew already on the orbiting laboratory.

SpaceX launched a rocket loaded with 6,000 pounds of supplies to the International Space Station on Monday night from the Florida coast.

The first wood-panel satellite is on a SpaceX flight to the International Space Station, where it will test the durability of wood in space.

The Liège-Guillemins railway station looks like it belongs far in the future: a vast curving monolith of glass, steel and concrete curves extending high above the train tracks. Just as astonishing as its design is the fact that it was built while the normal train schedules continued, with no disruption.

Read more at http://blogs.smithsonianmag.com/aroundthemall/2011/06/dancing-splash-mob-floods-the-natural-history-museum In an effort to celebrate World Oceans Day, organizers planned a "splash" mob at the National Museum of Natural History's Sant Ocean Hall.

The Town of Tecumseh will be getting six new EV charging stations, the province announced Tuesday, in a bid to "support the electrification of transportation across the province."

A handful of voting stations were temporarily closed due to power outages on Saturday morning during the final day of B.C.’s provincial election, while the only station in Dease Lake was fully closed because an election official had travel difficulties.

Apple is set to streamline its retail displays, making way for new Mac models by downgrading the Apple Vision Pro demo experience.

Glyde's specially designed sliding charging station is a great way to charge all your smaller Apple devices.

Check out the latest from Bluetti with an exclusive discount on the Elite 200 V2 portable power station capable of generating reliable 2 kWh power for 17 years.

Current charging stations for electric vehicles, or EVs, can be expensive to install, and limited in the number of parking spaces they reach. Penn State engineering student Jonathan Smith and his team have spent the last three years creating a possible solution: smaller, mounted charging stations, which can move to cover as many as five parking spaces. As CEO of Streamline Charging, he’s used his Penn State education and customized coursework to get the team’s ideas to market. 

Ahead of the film's release, Vikrant made a surprise visit to Godhra railway station on Monday, the site where the Sabarmati incident happened

State of Delaware, DuPont and University of Delaware partner to form Delaware Innovation Space, Inc.   WILMINGTON, Del. – Governor John Carney on Monday announced the creation of the Delaware Innovation Space, Inc. – a nonprofit public-private partnership established by the State of Delaware, DuPont, and the University of Delaware that will catalyze the entrepreneurial […]

Read the in depth Review of Synology DiskStation DS920+ Storage. Know detailed info about Synology DiskStation DS920+ configuration, design and performance quality along with pros & cons, Digit rating, verdict based on user opinions/feedback.

Read the in depth Review of PlayStation 5 Gaming. Know detailed info about PlayStation 5 configuration, design and performance quality along with pros & cons, Digit rating, verdict based on user opinions/feedback.

[SAPS] - Polokwane based Hawks Serious Commercial Crime Investigation in collaboration with National Traffic Anti-corruption Unit arrested 11 suspects between the ages of 27 and 57 for alleged fraud at various Provinces during operation "SISFIKILE".

LONDON — British writer Samantha Harvey won the Booker Prize for fiction on Tuesday with "Orbital," a short, wonder-filled novel set aboard the International Space Station that ponders the beauty and fragility of the Earth. Harvey was awarded the 50,000-pound ($64,000) prize for what she has called a "space pastoral" about six orbiting astronauts, which she began writing during COVID-19 pandemic lockdowns. The confined characters loop through 16 sunrises and 16 sunsets over the course of a day, trapped in one another's company and transfixed by the globe's ever-changing vistas. "To look at the Earth from space is like a child looking into a mirror and realizing for the first time that the person in the mirror is herself," said Harvey, who researched her novel by reading books by astronauts and watching the space station's live camera. "What we do to the Earth we do to ourselves." She said the novel "is not exactly about climate change, but implied in the view of the Earth is the fact of human-made climate change." She dedicated the prize to everyone who speaks "for and not against the Earth, for and not against the dignity of other humans, other life." "All the people who speak for and call for and work for peace — this is for you," she said. Writer and artist Edmund de Waal, who chaired the five-member judging panel, called "Orbital" a "miraculous novel" that "makes our world strange and new for us." Gaby Wood, chief executive of the Booker Prize Foundation, noted that "in a year of geopolitical crisis, likely to be the warmest year in recorded history," the winning book was "hopeful, timely and timeless." Harvey, who has written four previous novels and a memoir about insomnia, is the first British writer since 2020 to win the Booker. The prize is open to English-language writers of any nationality and has a reputation for transforming writers' careers. Previous winners include Ian McEwan, Margaret Atwood, Salman Rushdie and Hilary Mantel. De Waal praised the "crystalline" writing and "capaciousness" of Harvey's succinct novel — at 136 pages in its U.K. paperback edition, one of the shortest-ever Booker winners. "This is a book that repays slow reading," he said. He said the judges spent a full day picking their winner and came to a unanimous conclusion. Harvey beat five other finalists from Canada, the United States, Australia and the Netherlands, chosen from among 156 novels submitted by publishers. American writer Percival Everett had been the bookies' favorite to win with "James," which reimagines Mark Twain's "Huckleberry Finn" from the point of view of its main Black character, the enslaved man Jim. The other finalists were American writer Rachel Kushner's spy story "Creation Lake"; Canadian Anne Michaels' poetic novel "Held"; Charlotte Wood's Australian saga "Stone Yard Devotional"; and "The Safekeep" by Yael van der Wouden, the first Dutch author to be shortlisted for the Booker. Harvey is the first female Booker winner since 2019, though one of five women on this year's shortlist, the largest number in the prize's 55-year history. De Waal said issues such as the gender or nationality of the authors were "background noise" that did not influence the judges. "There was absolutely no question of box ticking or of agendas or of anything else. It was simply about the novel," he said before the awards ceremony at Old Billingsgate, a grand former Victorian fish market in central London. Founded in 1969, the Booker Prize is open to novels originally written in English published in the U.K. or Ireland. Last year's winner was Irish writer Paul Lynch for post-democratic dystopia "Prophet Song." Lynch handed Harvey her Booker trophy at the ceremony, warning her that her life was about to change dramatically because of the Booker publicity boost. Harvey said she was "overwhelmed" but remained down-to-earth about spending her prize money. She said she'd disburse "some of it on tax. I want to buy a new bike. And then the rest — I want to go to Japan."

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Lab-reared German cockroaches are susceptible to consumer insecticide sprays, allowing manufacturers to pass US regulatory tests, but insects taken from real-world infestations are able to shrug off the products

From artificial retinas to ageing mice, here are five of the most promising results from research performed on the ISS – and what they might mean for humans on Earth and in space

Title: Gestational Diabetes Ups Child Obesity
Category: Health News
Created: 8/29/2007 12:00:00 AM
Last Editorial Review: 8/29/2007 12:00:00 AM