Cierre del portal Usme afecta a 35,000 usuarios: Gerente de TrasnMilenio

Natalia Tinjacá, directora técnica de Transmilenio, habló sobre cómo afectó la movilidad de Transmilenio en bloqueo de vendedores ambulantes 

[Updated] Friday’s sitting of the House of Assembly saw a number of unusual “what if” questions posed, including queries pertaining to being kicked out of a church for stealing while committing adultery, being beaten up after sleeping with a neighbour’s wife and buying marijuana. This exchange followed a motion brought by Independent MP Terry Lister […]

Mapping Black London — which is led by Northeastern University and aims to “visualise the multi-racial foundations and histories of London and the UK” — has created an interactive map chronicling the life of Bermudian Mary Prince. The organization said, “This exhibit traces the life of Mary Prince through the locations she described in her […]

Jacinda Ardern is the prime minister of New Zealand. She decided to drop in and catch up with well known Twitch streamer, Broxh. What ensues is nothing short of a magical, wholesome interaction. 

The post Unusual Residents of Saint-Petersburg appeared first on English Russia.

The award supports independent research in the arts and humanities at the American Academy in Rome. Both Princeton recipients are undergraduate alumni.

A 30-minute guided tour of the latest exhibition in the Milberg Gallery in Firestone Library at Princeton University. Tours meet in the lobby of Firestone Library. The exhibition is open Monday to Friday from 10 a.m. to 6 p.m., and 11 a.m. to 6 p.m. on Saturday and Sunday in the Milberg Gallery, Firestone Library. Open to the public. “Monsters and Machines: Caricature, Visual Satire, and the Twentieth-Century Bestiary” will focus on the use of bestiary – animal or zoological motifs – in visual satire during the period between World War I and the end of the Cold War. Drawing from PUL’s rich collections of 20th-century posters, illustrated periodicals, and ephemera from North America, Europe, Asia, Eurasia, and the Middle East, the exhibition will look at works of weaponized visual humor created by and aimed at exponents of different national cultures and ideologies. The exhibition will run from September 12 to December 8, 2024.

In this talk, Graham Neubig will discuss a new frontier in AI models, vision-language models that understand the world's cultures. The talk will be in two parts. First, Neubig will discuss training of multilingual multimodal multicultural models that understand images and text, and have increased ability to answer culture-specific questions about multimodal data. Second, he will discuss work on "image transcreation", where models have been developed that can transform images to make them more relevant to a particular culture. This work has applications in a number of areas, such as cultural localization of educational materials (to accompany translated text). While these methods cover many languages, African and not, the talk will focus on examples specifically from the African context, and challenges we currently face therein.

Các băng người Việt và khách hàng của họ vận hành tách biệt với các nhóm khác, thận trọng và kín kẽ hơn.

Hurricanes Helene and Milton have bookended a particularly stormy period. What's behind it?

It was business as usual at the Lebombo border post between SA and Mozambique on Saturday morning, with vehicles moving freely between both countries after a shutdown earlier this week.

The main protease (3CL Mpro) from SARS–CoV-2, the etiological agent of COVID-19, is an essential enzyme for viral replication. 3CL Mpro possesses an unusual catalytic dyad composed of Cys145 and His41 residues. A critical question in the field has been what the protonation states of the ionizable residues in the substrate-binding active-site cavity are; resolving this point would help understand the catalytic details of the enzyme and inform rational drug development against this pernicious virus. Here, we present the room-temperature neutron structure of 3CL Mpro, which allowed direct determination of hydrogen atom positions and, hence, protonation states in the protease. We observe that the catalytic site natively adopts a zwitterionic reactive form in which Cys145 is in the negatively charged thiolate state and His41 is doubly protonated and positively charged, instead of the neutral unreactive state usually envisaged. The neutron structure also identified the protonation states, and thus electrical charges, of all other amino acid residues and revealed intricate hydrogen-bonding networks in the active-site cavity and at the dimer interface. The fine atomic details present in this structure were made possible by the unique scattering properties of the neutron, which is an ideal probe for locating hydrogen positions and experimentally determining protonation states at near-physiological temperature. Our observations provide critical information for structure-assisted and computational drug design, allowing precise tailoring of inhibitors to the enzyme's electrostatic environment.

Eiji Kinoshita
Apr 1, 2006; 5:749-757
Technology

Persuasion or manipulation? Limiting campaigning online Expert comment NCapeling 15 February 2021

To tackle online disinformation and manipulation effectively, regulators must clarify the dividing line between legitimate and illegitimate campaign practices.

Democracy is at risk, not only from disinformation but from systemic manipulation of public debate online. Evidence shows social media drives control of narratives, polarization, and division on issues of politics and identity. We are now seeing regulators turn their attention to protecting democracy from disinformation and manipulation. But how should they distinguish between legitimate and illegitimate online information practices, between persuasive and manipulative campaigning?

Unregulated, the tactics of disinformation and manipulation have spread far and wide. They are no longer the preserve merely of disaffected individuals, hostile international actors, and authoritarian regimes. Facebook’s periodic reporting on coordinated inauthentic behaviour and Twitter’s on foreign information operations reveal that militaries, governments, and political campaigners in a wide range of countries, including parts of Europe and America, have engaged in manipulative or deceptive information campaigns.

For example, in September 2019, Twitter removed 259 accounts it says were ‘falsely boosting’ public sentiment online that it found to be operated by Spain’s conservative and Christian-democratic political party Partido Popular. In October 2020, Facebook removed accounts with around 400,000 followers linked to Rally Forge, a US marketing firm which Facebook claims was working on behalf of right-wing organisations Turning Point USA and Inclusive Conservation Group. And in December 2020, Facebook took down a network of accounts with more than 6,000 followers, targeting audiences in Francophone Africa and focusing on France’s policies there, finding it linked with individuals associated with the French military.

Public influence on a global scale

Even more revealingly, in its 2020 Global Inventory of Organized Social Media Manipulation, the Oxford Internet Institute (OII) found that in 81 countries, government agencies and/or political parties are using ‘computational propaganda’ in social media to shape public attitudes.

These 81 countries span the world and include not only authoritarian and less democratic regimes but also developed democracies such as many EU member states. OII found that countries with the largest capacity for computational propaganda – which include the UK, US, and Australia – have permanent teams devoted to shaping the online space overseas and at home.

OII categorizes computational propaganda as four types of communication strategy – the creation of disinformation or manipulated content such as doctored images and videos; the use of personal data to target specific segments of the population with disinformation or other false narratives; trolling, doxing or online harassment of political opponents, activists or journalists; and mass-reporting of content or accounts posted or run by opponents as part of gaming the platforms’ automated flagging, demotion, and take-down systems.

Doubtless some of the governments included within OII’s statistics argue their behaviour is legitimate and appropriate, either to disseminate information important to the public interest or to wrestle control of the narrative away from hostile actors. Similarly, no doubt some political campaigners removed by the platforms for alleged engagement in ‘inauthentic behaviour’ or ‘manipulation’ would defend the legitimacy of their conduct.

The fact is that clear limits of acceptable propaganda and information influence operations online do not exist. Platforms still share little information overall about what information operations they see being conducted online. Applicable legal principles such as international human rights law have not yet crystallised into clear rules. As information operations are rarely exposed to public view – with notable exceptions such as the Cambridge Analytica scandal – there is relatively little constraint in media and public scrutiny or censure.

OII’s annual reports and the platforms’ periodic reports demonstrate a continual expansion of deceptive and manipulative practices since 2016, and increasing involvement of private commercial companies in their deployment. Given the power of political influence as a driver, this absence of clear limits may result in ever more sophisticated techniques being deployed in the search for maximal influence.

Ambiguity over reasonable limits on manipulation plays into the hands of governments which regulate ostensibly in the name of combating disinformation, but actually in the interests of maintaining their own control of the narrative and in disregard of the human right to freedom of expression. Following Singapore’s 2019 prohibition of online untruths, 17 governments ranging from Bolivia to Vietnam to Hungary passed regulations during 2020 criminalising ‘fake news’ on COVID-19 while many other governments are alleged to censor opposition arguments or criticisms of official state narratives.

Clear limits are needed. Facebook itself has been calling for societal discussion about the limits of acceptable online behaviour for some time and has issued recommendations of its own.

The European Democracy Action Plan: Aiming to protect pluralism and vigour in democracy

The European Democracy Action Plan (EDAP), which complements the European Commission’s Digital Services Act and Digital Markets Act proposals, is a welcome step. It is ground-breaking in its efforts to protect the pluralism and vigour of European democracies by tackling all forms of online manipulation, while respecting human rights.

While the EDAP tackles disinformation, it also condemns two categories of online manipulation – information influence operations which EDAP describes as ‘coordinated efforts by either domestic or foreign actors to influence a target audience using a range of deceptive means’ and foreign interference, described as ‘coercive and deceptive efforts to disrupt the free formation and expression of individuals’ political will by a foreign state actor or its agents’. These categories include influence operations such as harnessing fake accounts or gaming algorithms, and the suppression of independent information sources through censorship or mass reporting.

But the categories are so broad they risk capturing disinformation practices not only of rogue actors, but also of governments and political campaigners both outside and within the EU. The European Commission plans to work towards refined definitions. Its discussions with member states and other stakeholders should start to determine which practices ought to be tackled as manipulative, and which ought to be tolerated as legitimate campaigning or public information practices.

The extent of the EDAP proposals on disinformation demonstrates the EU’s determination to tackle online manipulation. The EDAP calls for improved practical measures building on the Commission’s 2020 acceleration of effort in the face of COVID-19 disinformation. The Commission is considering how best to impose costs on perpetrators of disinformation, such as by disrupting financial incentives or even imposing sanctions for repeated offences.

Beyond the regulatory and risk management framework proposed by the Digital Services Act (DSA), the Commission says it will issue guidance for platforms and other stakeholders to strengthen their measures against disinformation, building on the existing EU Code of Practice on Disinformation and eventually leading to a strengthened Code with more robust monitoring requirements. These are elements of a broader package of measures in the EDAP to preserve democracy in Europe.

Until there are clear limits, manipulative practices will continue to develop and to spread. More actors will resort to them in order not to be outgunned by opponents. It is hoped forthcoming European discussions – involving EU member state governments, the European Parliament, civil society, academia and the online platforms – will begin to shape at least a European and maybe a global consensus on the limits of information influence, publicly condemning unacceptable practices while safeguarding freedom of expression.

Most importantly, following the example of the EDAP, the preservation of democracy and human rights – rather than the promotion of political or commercial interest – should be the lodestar for those discussions.

Expert

Visualizing the Data: The Evolution of Trade Tensions in Metals and Minerals Markets 18 January 2018 — 4:30PM TO 6:00PM Anonymous (not verified) 19 December 2017 Chatham House, London

Over the past decade, producer countries such as South Africa, Zambia, Indonesia, the DRC and, most recently, Tanzania have restricted exports of unprocessed precious metals, copper, nickel, cobalt and other minerals in an attempt to support, or create, downstream processing industries and jobs or increase revenues. These moves have invariably created tensions with trading partners. Research suggests that export restrictions are not the best way to achieve such policy objectives and can instead harm the producer country’s economy and undermine the functioning of international metals and minerals.

Drawing on OECD and Chatham House research on resource trade, the speaker will present analysis and data visualizations exploring the drivers of past export restrictions and their political and economic impacts. They will also consider how the drivers of ‘resource nationalist measures’ are changing, whether and where export restrictions might present strategic and economic risks in the current context, and the extent to which producer and consumer governments and international governance mechanisms are prepared to address them.

Attendance at this event is by invitation only.

When using the distinct count function in SAS Visual Analytics reports, you might find that a negative value is displayed instead of the actual distinct count: imgalt="distinct_count" src="{fusion_66562_1_disti

Mitochondrial DNA (mtDNA) encodes proteins and RNAs that support the functions of mitochondria and thereby numerous physiological processes. Mutations of mtDNA can cause mitochondrial diseases and are implicated in aging. The mtDNA within cells is organized into nucleoids within the mitochondrial matrix, but how mtDNA nucleoids are formed and regulated within cells remains incompletely resolved. Visualization of mtDNA within cells is a powerful means by which mechanistic insight can be gained. Manipulation of the amount and sequence of mtDNA within cells is important experimentally and for developing therapeutic interventions to treat mitochondrial disease. This review details recent developments and opportunities for improvements in the experimental tools and techniques that can be used to visualize, quantify, and manipulate the properties of mtDNA within cells.

Junhwan Kim
Dec 1, 2020; 61:1707-1719
Research Articles

If you have configured more than one SAS Application Server, then SAS Visual Data Builder might unexpectedly use the wrong application server when you preview or schedule queries. This problem occurs even though you h

When viewing a SAS Visual Analytics report, you might intermittently see an error that includes content similar to the following:

Driven by the energy of a photon, the visual pigments in rod and cone photoreceptor cells isomerize 11-cis-retinal to the all-trans configuration. This photochemical reaction initiates the signal transduction pathway that eventually leads to the transmission of a visual signal to the brain and leaves the opsins insensitive to further light stimulation. For the eye to restore light sensitivity, opsins require recharging with 11-cis-retinal. This trans–cis back conversion is achieved through a series of enzymatic reactions composing the retinoid (visual) cycle. Although it is evident that the classical retinoid cycle is critical for vision, the existence of an adjunct pathway for 11-cis-retinal regeneration has been debated for many years. Retinal pigment epithelium (RPE)–retinal G protein-coupled receptor (RGR) has been identified previously as a mammalian retinaldehyde photoisomerase homologous to retinochrome found in invertebrates. Using pharmacological, genetic, and biochemical approaches, researchers have now established the physiological relevance of the RGR in 11-cis-retinal regeneration. The photoisomerase activity of RGR in the RPE and Müller glia explains how the eye can remain responsive in daylight. In this review, we will focus on retinoid metabolism in the eye and visual chromophore regeneration mediated by RGR.  

Phospholipids, including ether phospholipids, are composed of numerous isomeric and isobaric species that have the same backbone and acyl chains. This structural resemblance results in similar fragmentation patterns by collision-induced dissociation of phospholipids regardless of class, yielding complicated MS/MS spectra when isobaric species are analyzed together. Furthermore, the presence of isobaric species can lead to misassignment of species when made solely based on their molecular weights. In this study, we used normal-phase HPLC for ESI-MS/MS analysis of phospholipids from bovine heart mitochondria. Class separation by HPLC eliminates chances for misidentification of isobaric species from different classes of phospholipids. Chromatography yields simple MS/MS spectra without interference from isobaric species, allowing clear identification of peaks corresponding to fragmented ions containing monoacylglycerol backbone derived from losing one acyl chain. Using these fragmented ions, we characterized individual and isomeric species in each class of mitochondrial phospholipids, including unusual species, such as PS, containing an ether linkage and species containing odd-numbered acyl chains in cardiolipin, PS, PI, and PG. We also characterized monolysocardiolipin and dilysocardiolipin, the least abundant but nevertheless important mitochondrial phospholipids. The results clearly show the power of HPLC-MS/MS for identification and characterization of phospholipids, including minor species.

BOSTON, Dec. 12, 2023 — Aliro Quantum today announced the controlled availability of Aliro Simulator, a versatile, modular quantum network simulator equipped to model all portions of a quantum network from […]

The post Aliro Quantum Debuts Aliro Simulator, Enhancing Quantum Network Simulation and Visualization appeared first on HPCwire.

PITTSBURGH, June 19, 2024 — Ansys today announced that it is adopting NVIDIA Omniverse application programming interfaces (APIs) to offer 3D-IC designers valuable insights from Ansys’ physics solver results through […]

The post Ansys Enables 3D Multiphysics Visualization of Next-Gen 3D-IC Designs with NVIDIA Omniverse appeared first on HPCwire.

Many people overthink persuasion, when it is the most natural approaches that work best.

Michele Deodato
Oct 2, 2024; 44:e2308232024-e2308232024
BehavioralSystemsCognitive

Kyle E. Mathewson
Mar 4, 2009; 29:2725-2732
BehavioralSystemsCognitive

Gijs Joost Brouwer
Nov 4, 2009; 29:13992-14003
BehavioralSystemsCognitive

Recent visual experience heavily influences our visual perception, but how neuronal activity is reshaped to alter and improve perceptual discrimination remains unknown. We recorded from populations of neurons in visual cortical area V4 while two male rhesus macaque monkeys performed a natural image change detection task under different experience conditions. We found that maximizing the recent experience with a particular image led to an improvement in the ability to detect a change in that image. This improvement was associated with decreased neural responses to the image, consistent with neuronal changes previously seen in studies of adaptation and expectation. We found that the magnitude of behavioral improvement was correlated with the magnitude of response suppression. Furthermore, this suppression of activity led to an increase in signal separation, providing evidence that a reduction in activity can improve stimulus encoding. Within populations of neurons, greater recent experience was associated with decreased trial-to-trial shared variability, indicating that a reduction in variability is a key means by which experience influences perception. Taken together, the results of our study contribute to an understanding of how recent visual experience can shape our perception and behavior through modulating activity patterns in the mid-level visual cortex.

It is well established that holding information in working memory (WM) elicits sustained stimulus-specific patterns of neural activity. Nevertheless, here we provide evidence for a distinct class of neural activity that tracks the number of individuated items in working memory, independent of the type of visual features stored. We present two EEG studies of young adults of both sexes that provide robust evidence for a signal tracking the number of individuated representations in working memory, regardless of the specific feature values stored. In Study 1, subjects maintained either colors or orientations across separate blocks in a single session. We found near-perfect generalization of the load signal between these two conditions, despite being able to simultaneously decode which feature had been voluntarily stored. In Study 2, participants attended to two features with very distinct cortical representations: color and motion coherence. We again found evidence for a neural load signal that robustly generalized across these distinct visual features, even though cortically disparate regions process color and motion coherence. Moreover, representational similarity analysis provided converging evidence for a content-independent load signal, while simultaneously showing that unique variance in EEG activity tracked the specific features that were stored. We posit that this load signal reflects a content-independent "pointer" operation that binds objects to the current context while parallel but distinct neural signals represent the features that are stored for each item in memory.

The Black Death of 1348 was a devastating event, wiping out half the population of Britain. And in churches like this one, drawings on the wall provide a haunting visual record of the scale of the tragedy.

The annual award ceremony featured costumes, songs and paper airplanes as scientists recognized comedic research across ten disciplines

A new exhibition at the Smithsonian's National Museum of Natural History combines satellite observations and historical data to offer a "larger-than-life look" at our planet's climate today

In insects, oocyte resorption (oosorption) or follicular atresia is one of the key physiological processes and evolutionary strategies used to optimize reproductive fitness. Mosquitoes are ideal model organisms for studying egg maturation in arthropods, as their follicle development is initiated only following the ingestion of a blood meal, followed by a carefully orchestrated series of hormonally regulated events leading to egg maturation. A cohort of approximately 100 follicles per mosquito ovary begin developing synchronously. However, a significant fraction of follicles ultimately undergo apoptosis and oosorption, especially when available resources from the blood meal are limited. Therefore, simple, rapid, and reliable techniques to accurately evaluate follicular atresia are necessary to understand mechanisms underlying follicle development in insects. This protocol describes how to detect apoptotic follicle cells within the Aedes aegypti mosquito ovaries using a commercially available fluorescent-labeled inhibitor of caspases (FLICA). Caspases are key players in animal apoptosis. In this assay, the FLICA reagent enters the intracellular compartment of follicles in dissected mosquito ovaries and covalently binds to active caspases. The bound reagent remains within the cell and its fluorescent signal can be observed by confocal microscopy. Although this method was specifically developed for visualizing apoptotic ovarian follicles during Ae. aegypti mosquito egg development, it should be applicable to other mosquito tissues that undergo caspase-mediated program cell death in a time-dependent manner.

The latest episode of "Growing Impact" explores how a research team is using computer modeling and animations to visualize future flood and levee failure scenarios.

NEW CASTLE (22 de Febrero de 2022) – La División de Servicios Sociales de Delaware emitirá beneficios de emergencia para Febrero a los hogares elegibles como parte de la respuesta continua del estado a la crisis de salud pública de COVID-19. Los beneficios se emitirán como parte del Programa de Asistencia Nutricional Suplementaria (SNAP) y […]

NEW CASTLE (23 de Marzo de 2022) – La División de Servicios Sociales de Delaware emitirá beneficios de emergencia para Marzo a los hogares elegibles como parte de la respuesta continua del estado a la crisis de salud pública de COVID-19. Los beneficios se emitirán como parte del Programa de Asistencia Nutricional Suplementaria (SNAP) y […]

NEW CASTLE (26 de Abril de 2022) – La División de Servicios Sociales de Delaware emitirá beneficios de emergencia para Abril a los hogares elegibles como parte de la respuesta continua del estado a la crisis de salud pública de COVID-19. Los beneficios se emitirán como parte del Programa de Asistencia Nutricional Suplementaria (SNAP) y […]

NEW CASTLE (25 de Mayo de 2022) – La División de Servicios Sociales de Delaware emitirá beneficios de emergencia para Mayo a los hogares elegibles como parte de la respuesta continua del estado a la crisis de salud pública de COVID-19. Los beneficios se emitirán como parte del Programa de asistencia nutricional suplementaria (SNAP) y […]

NEW CASTLE (28 de Junio de 2022) – La División de Servicios Sociales de Delaware emitirá beneficios de emergencia para Junio a los hogares elegibles como parte de la respuesta continua del Estado a la crisis de salud pública de COVID-19. Los beneficios se emitirán como parte del Programa de Asistencia Nutricional Suplementaria (SNAP) y […]

SAS Visual Text Analytics can easily analyze similar words and phrases coming from various cultural heritage-related documents to construct a heritage wordbook that cultural workers can use to identify what relevant conservation technique to use on a structure/artifact.

Building a cultural wordbook via SAS Visual Text Analytics was published on SAS Users.

This phenomenon has been in the news recently, so I've updated this article that I originally published in 2017. The paper currency in circulation in the US is mostly $100 bills. And not just by a little bit -- these account for 34% of the notes by denomination and nearly [...]

The post Visualized: US Currency in circulation, past and present appeared first on The SAS Dummy.

We live in the age of data. From global warming stats to customer behavior patterns, new technologies have made it easier to collect, store, access and analyze information. But our use of these technologies has also eroded our attention spans and fueled post-truth misunderstandings. To combat these trends, the question [...]

SAS Customer Intelligence 360: Visual analytics, sankey diagrams and customer journeys was published on Customer Intelligence Blog.

Everything happens somewhere, and much of our customer data includes location information. Websites include x, y coordinates in semi-structured click streams, and the mobile apps your prospects depend on frequently support device location to provide a personalized, targeted experience. As my SAS peer Robby Powell said: "Human brains are hardwired [...]

SAS Customer Intelligence 360: Data visualization, location analytics and geospatial insights was published on Customer Intelligence Blog.

Read the in depth Review of CloudWalker 55 Inches 4K Ultra HD Smart LED Screen (55SUA7) TV. Know detailed info about CloudWalker 55 Inches 4K Ultra HD Smart LED Screen (55SUA7) configuration, design and performance quality along with pros & cons, Digit rating, verdict based on user opinions/feedback.