India's consumer price inflation likely surged to a 14-month high in October, driven by soaring vegetable and edible oil prices. Economists predict inflation hit 5.81%, just below the central bank's 6% tolerance limit. A weak rupee and rising global commodity prices add to inflationary pressures, potentially delaying anticipated interest rate cuts.

Furnishka will use the new capital to advance product design and development, strengthen manufacturing and supply chain capabilities, and expand to new geographies. The company will also expand its product categories focused on premium living room, dining room and bedroom collections, open six large-format stores, and create educational content to guide customers.

Rentomojo reported a 60% rise in operating revenue to Rs 193 crore in FY24. Controlled rise in expenses during the year saw net profit surge more than threefold to Rs 22 crore last fiscal from Rs 6 crore in FY23.

Manos Nikolakis, GM, BIC Cello, said, "While e-commerce is growing significantly across the country, the landscape of the Indian market is still heavily reliant on traditional trade. Accordingly, this remains our main sales driver. The lack of digital penetration in semi-urban and rural areas can sometimes create a challenge in the e-commerce space, which means that e-commerce is mostly relevant in bigger cities with a more mature infrastructure."

La Luciérnaga se enciende para hablar del senador Jota Pe Hernández, quien tras el incremento del salario de los congresistas explicó la alternativa que queda para bajar el salario. De acuerdo con el congresista, el proyecto que presentó ya pasó el primer debate en la Comisión Primera del Senado y le falta un debate más allí. Se debe destacar que esta polémica no es nueva, pues desde hace años, se ha buscado que la diferencia entre el salario de los congresistas y el salario mínimo que gana un colombiano no sea tan exagerado. También, la alcaldesa de Bogotá, Claudia López, aseguró que no hay acuerdo entre el Gobierno y el Distrito para la modificación de la primera línea del metro, para que un tramo sea subterráneo. Así, el presidente Gustavo Petro respondió asegurando que ante esta situación el Gobierno ha sido engañado. Y por último, estrenamos nuestra sección "el tablero político de La Luciérnaga" nuestro principal tema fue: Los Godos se van con Dilian Francisca Toro para la Gobernación del Valle. 
La Luciérnaga, un espacio de humor y opinión de Caracol Radio que acompaña desde hace más de 30 años a sus oyentes en el regreso a casa.

A response from Fang Wengen, the lawyer of Mrs Yang Huiyan

When something is on the ballot that will hurt the National Western Stock Show, the Denver Powwow, our fly-fishing businesses and hatmakers, that should rile us all up. Hands off our hats!

There are no regulations or federal laws protecting the animals as they languish in small, wire-bottomed cages for their entire lives.

Denver voters were giving a strong thumbs-down Tuesday night to ballot measures that would ban businesses from making or selling fur-based products and outlaw slaughterhouses within city limits.

Courtland Sutton and the Broncos were still celebrating his 32-yard touchdown catch in the second quarter Sunday when the tremor preceding the earthquake rippled.

His efforts weren’t ‘good enough,’ he says.

Minister of Youth, Social Development and Seniors Tinee Furbert is attending the XVI Ministerial Development Forum for Latin America and the Caribbean from 30 October to 1 November 2024 in Bridgetown, Barbados. A Government spokesperson said, “The theme for this year’s Forum is ‘Resilience in Action: Social Policies to Navigate Uncertainty in Latin America and […]

Minister of Transport Wayne Furbert provided an overview of the 2024 cruise ship season, stating that ”comparing the 2023 season, which saw 183 calls and 41 cancellations with 525,413 passengers, to 2024, we project a marginal increase of 22,651 passengers or 4.3%, and a small decrease in the number of cruise calls by 6 or 3.2%.” The Minister’s […]

In the wake of the devastation rendered by Hurricane Helene, Carolina Furfare released a newsletter on October 1 stating the cancellation of the event that was to occur this weekend, and indicating that the hotels and facilities were needed in order to assist with rescue and sheltering efforts after the Hurricane hit the mountainous region.

This weather event hit the top ten most fatal and costly hurricanes in the United States even before full recovery efforts could be finalized. People who pre-registered have been given the option to roll over to next year, or to Bewhiskered 2025; due to the cancellation being so close to event day they cannot guarantee refunds for now.

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The 2024 Good Furry Awards were presented this Tuesday, 15 October, at Biggest Little Fur Con.

This year saw the Award divided into three categories, the winners of which were:

• Image Award: Finn the Panther
• Furtastic Award: Spottacus Cheetah
• Good Egg Award: Shutter Karelian

Meanwhile, 2024's Lifetime Achievement award was presented to Albedo creator Steve Gallacci.

We have another GIANT list of games this season for the Fall 2024 Steam Next Fest! We're looking forward to a ton of these, and have compiled as many as we could find with animals and/or anthropomorphic characters featured in them! Be sure to let us know of any others you find by commenting below!

We'll be playing some of these demos this week and next, and hopefully providing some previews and progress updates throughout development! Additionally, we have an actively updated Furry & Animal Games List over at @GamingFurever that you can follow and get updates for lots of indie titles with TONS of lovely furry characters!

If you're a developer of any of these games, feel free to hit us up on email over on our Contact Us page!

We're sure everyone will find at least a couple games that strike their fancy during this Next Fest!

Check out the full October list here!

Yes, aiffinkso!

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If you're looking to save big on your next outdoor furniture splurge, now's the ultimate time. READ MORE...

We’ve all been there – the frustration of searching high and low for that elusive piece of furniture to turn our home decorating vision into reality. For Sabrina, her search was for the ideal console table. “Unfortunately, I could not find the perfect console, so my husband had to believe in it again and build one himself!” she shared on her Instagram post. After realizing that the perfect entryway console was nowhere to be found, the couple decided to take […]

The post Failed Furniture Hunt Inspires Couple’s Fabulous Entryway Console Hack appeared first on IKEA Hackers.

Wood is one of the most common materials used for manufacturing and construction. Despite it being a natural resource with potential for reuse and its biodegradable qualities, the wood used in the industry is far from circular. In fact, each year, millions of tons of this precious material are wasted. To prevent this, a group of designers from the firm Disrupt.Design Lab (D.DLAB) have been exploring the development of circular solutions for wood. By developing new techniques that combine advanced fabrication and traditional methods, the team aims to contribute to the development of zero-waste industries.[...]

With roots in America, western-style furniture is a traditional and vintage style. There are many reasons to admire such furniture, whether captivated by its timeless beauty or collecting and displaying them as part of one’s house decor. People have a particular appreciation for and attraction to Western-style because of its traditional and rustic charm. People ... Read more

The post Western Rustic Charm: Creating A Personalized Retreat With Western-Style Furniture appeared first on Star Two.

6 Common Furniture Mistakes to Avoid

The Archbishop of Canterbury has announced he will step down over a damning report into abuse.

Donald Trump has riled the left-wing, anti-American Democrats once again, this time by naming Biden critic and immigration expert Thomas D. Homan as his “border czar.” Homan is an excellent choice for this, certainly. No one knows more about fixing border policy better than Homan who ha spent the last 5 years bedeviling the left […]

The post Donald Trump’s New Border Czar Means Business… and Democrats are Furious appeared first on The Lid.

Carlota Oleaga
Nov 17, 2020; 0:jlr.RA120000964v1-jlr.RA120000964
Research Articles

Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates cholesterol metabolism by inducing the degradation of hepatic low-density lipoprotein receptor (LDLR). Plasma PCSK9 has two main molecular forms: a 62-kDa mature form (PCSK9_62) and a 55-kDa, furin-cleaved form (PCSK9_55). PCSK9_55 is considered less active than PCSK9_62 in degrading LDLR. We aimed to identify the site of PCSK9_55 formation (intra- vs. extracellular) and to further characterize the LDLR-degradative function of PCSK9_55 relative to PCSK9_62. Co-expressing PCSK9_62 with furin in cell culture induced formation of PCSK9_55, most of which was found in the extracellular space. Under the same conditions we found that: i) adding a cell-permeable furin inhibitor preferentially decreased the formation of PCSK9_55 extracellularly; ii) using pulse-chase, we observed the formation of PCSK9_55 exclusively extracellularly in a time-dependent manner. A recombinant form of PCSK9_55 was efficiently produced but displayed impaired secretion that resulted in its intracellular trapping. However, the non-secreted PCSK9_55 was able to induce degradation of LDLR, though with 50% lower efficiency compared with PCSK9_62. Collectively, our data show that PCSK9_55 is generated in the extracellular space, and that intracellular PCSK9_55 is not secreted but retains the ability to degrade the LDLR through an intracellular pathway.

The Biden administration has sanctioned the West Darfur commander of the Rapid Support Forces on accusations that troops under his control have been responsible for violence targeting civilians.

ATHENS, Ga. — With five players scoring in double-figures, the Georgia Lady Bulldogs defeated Furman, 74-46, on a rainy Sunday afternoon at Stegeman Coliseum. Fast Facts * Sunday’s matchup marked the 14th-straight year that Georgia and Furman have met during the regular season. The Lady Dogs lead the series 21-0, which includes a 17-0 record at home. * The Lady Dogs went on a 14-0 run at the ...

The apartment once occupied by the author of Les Miserables is now a museum dedicated to his life and to 19th century Paris

An OM worker from Latin America uses his carpentry skills to disciple young men in their faith and give them better employment opportunities for the future.

After nearly six complete seasons, the Canadian Premier League finds itself at an inflection point. Ahead of Saturday’s championship match, it appears there’s some stability — and, consequently, an opportunity to further establish the league’s place within the rapidly growing soccer landscape.

The Kamloops School District has made further cuts, including staff reductions, as it faces a budget deficit of more than $2 million from the 2023-24 school year.

With 3D CAD, Company Reduces Design Cycle from Three Weeks to Three or Four Days

Longtime U.K. office furniture maker streamlines custom, quality product development

New version of content delivery Web site boosts innovation and productivity

A local church, with the help of the OM team, starts a café ministry in their second-hand shop in Råslätt, Sweden.

The percentage of U.S. public school teachers participating in unions has been declining steadily over the last two decades—and the numbers are soon likely to take an even steeper dive.

DOVER, DE (Oct. 10, 2022) – Delaware’s cancer mortality, or death, rate has further declined, according to the latest cancer data from the Division of Public Health (DPH).  Between 2005 and 2019, mortality rates for cancer at all locations throughout the body, known as all-site cancer, decreased an average of 1.7% per year in both Delaware and […]

NEW CASTLE (March 19, 2024) – The Delaware Department of Health and Social Services and Governor John Carney announced additional investments in child care for the upcoming year. Building on the Governor’s Recommended Budget, which proposes expanding eligibility for Purchase of Care to 200% of the Federal Poverty Level (FPL) and creating over 200 additional […]

[Daily Maverick] Office of the Chief Justice reveals Constitutional Court has been unable to sit because of unreliable water supply. This article is free to read.Sign up for free or sign in to continue reading.Unlike our competitors, we don't force you to pay to read the news but we do need your email address to make your experience better.Create your free account or sign in FAQ | Contact Us Nearly there! Create a password to finish signing up with us: You want to receive First Thing, our flagship daily newsletter. Opt

The federal state of Brandenburg is committed to ensuring investors are welcomed into Frankfurt (Oder) through a string of generous incentives.

Frankfurt (Oder) is building on the strengths of its university to foster the development of successful start-ups through new co-working spaces and the promotion of sustainable practices and products. 

AstraZeneca will set up a R&D centre and an AI innovation centre in Shanghai, as well as create a $1bn fund that would invest in healthcare start-ups.

Save 57% on a pair of refurbished Dyson Corrale straighteners at Walmart.

Save 37% on a refurbished Dyson Airwrap at Walmart.

The Hisense 50" Class R6 Series 4K UHD Roku Smart TV is currently on sale for $138 at Walmart's early Black Friday sale — get it now and save 43% or $100-off.