Brain tumors or glioblastomas are one of the most difficult cancer types to treat. These masses are malignant tumors that are made up of abnormal neuronal

Brain tumors or glioblastomas are one of the most difficult cancer types to treat. These masses are malignant tumors that are made up of abnormal neuronal

High-grade glioma (HGG), a type of aggressive brain cancer, accounts for the leading cause of cancer-related mortality for children and adolescents. 

Pilocytic astrocytomas are the most common pediatric brain tumors, typically presenting as low-grade neoplasms. We report two cases of pilocytic astrocytoma with atypical tumor progression. Case 1 involves a 12-yr-old boy with an unresectable suprasellar tumor, negative for BRAF rearrangement but harboring a BRAF p.V600E mutation. He experienced tumor size reduction and stable disease following dabrafenib treatment. Case 2 describes a 6-yr-old boy with a thalamic tumor that underwent multiple resections, with no actionable driver detected using targeted next-generation sequencing. Whole-genome and RNA-seq analysis identified an internal tandem duplication in FGFR1 and RAS pathway activation. Future management options include FGFR1 inhibitors. These cases demonstrate the importance of escalating molecular diagnostics for pediatric brain cancer, advocating for early reflexing to integrative whole-genome sequencing and transcriptomic profiling when targeted panels are uninformative. Identifying molecular drivers can significantly impact treatment decisions and improve patient outcomes.

Newly discovered targets may hold the key to effectively treating glioblastoma, a deadly form of brain cancer. These targets were identified by screening

Recent trials have shown that immunotherapy can safely be delivered through injections into the cerebrospinal fluid; scientists are now exploring how to adapt these methods to penetrate the tumour more effectively

Few relationships would be immune to the pressures wrought by their ordeal: the strain of caring for their desperately sick child, their brief life as fugitives, the draining legal battles.

Few relationships would be immune to the pressures wrought by their ordeal: the strain of caring for their desperately sick child, their brief life as fugitives, the draining legal battles.

The field of film and television in India has lost a number of gems in the past few days. In another setback, revered Doordarshan presenter Malvika Marathe breathed her last on May 7, 2020.  The anchor and actress was 53.   Malvika

The field of film and television in India has lost a number of gems in the past few days. In another setback, revered Doordarshan presenter Malvika Marathe breathed her last on May 7, 2020.  The anchor and actress was 53.   Malvika

People with brain cancer are at increased risk for suicide compared to the general population, particularly within the first year following diagnosis, a new analysis has found.

Title: Could AI Help Doctors Map Out Treatments for Brain Cancers?
Category: Health News
Created: 4/24/2020 12:00:00 AM
Last Editorial Review: 4/27/2020 12:00:00 AM

Tributes have poured in for Scrubs actor Sam Lloyd, who has died at the age of 56.

Highlights: Zika virus can specifically kill brain cancer cells, without harming normal cells It

Medication used to treat non-small cell lung cancer that has metastasized, may benefit patients with metastatic brain cancers, according to a new review and analysis led by researchers at St.

There are no targeted therapies or immunotherapies proven effective to treat pediatric brain cancer better than chemotherapy. In fact, chemotherapy has

Brain cancer patients typically need a biopsy so physicians can assess their mutation status and make a treatment decision. But, a new AI (Artificial

TPR gene is closely linked to ependymoma. It can help with not just diagnosis, but also treatment options for the condition, according to Richard Wong's

The One Pound Warriors Facebook page was launched by Lillie Cotgrove, 13, from Benfleet, Essex, to raise money for her best friend Lily Wythe, 14, who is suffering with brain cancer.

Carrie Bickmore caught up with the judges from Masterchef on Tuesday, where they donned her popular Beanies 4 Brain Cancer head wear.

Carrie Bickmore, host of Australian talk show The Project has released a new range of headwear called Carrie’s Beanies 4 Brain Cancer to raise money for brain cancer research.

Ashan Corrick, 25, from Filton, Bristol, was diagnosed with brain cancer at Southmead Hospital on August 17, after suffering a headache for just two days. He died on December 17.

Nikita Pearl played Gloria in the film - also starring Lupita Nyong'o - about a chess prodigy from a Ugandan slum. She died at hospital in Naalya, Kampala, last night, Ugandan media reports.