Williams will put safety first even though the team is one of several whose survival depends on Formula One starting racing again, deputy principal Claire Williams said.

Vegas, here we come. All of us fun EDA engineers at once. Be prepared, next week’s Design Automation Conference will be busy! The trends I had outlined after last DAC in 2018—system design, cloud, and machine learning—have...(read more)

Collection of articles covering safety and security of dams and civil structures

The North Carolina Attorney General's Office has filed a court injunction against the German ownership group that owns the damaged Woodlake Dam in an effort to make it pay for dam safety repairs.

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Amidst the attention grabbing hysteria of Coronavirus headlines, some commentators have speculated that employers may be about to face prosecution if they don’t take all precautions possible to protect staff and third parties from infection. I...

On 29 April 2020, a directive addressing the implementation of necessary occupational health and safety measures in workplaces to reduce and eliminate the escalation of Covid-19 infections (“Directive”) was published. The Occupational He...

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INTRODUCTION The COVID-19 Regulations issued by the government have required persons to work from home, where they can. As we have engaged with our clients on a daily basis, one of the key questions is whether a person’s home becomes a “...

On 17 March 2020, we sent out an e-Brief: Occupational Health and Safety: COVID-19 (click here to access this e-brief) where we discussed the responsibilities which are placed on employers in terms...

Are you comfortable with latest government guidelines on working in a pandemic? Are you enforcing social distancing? In a sea of ‘fake news’ do you understand how Coronavirus is actually spread and what is safe and unsafe?...

Prosecutions are down. There is no new safety law, and Brexit should not make much difference, but employers cannot drop their guard when it comes to the health and safety of people. ...

Overview for owners and occupiers 1. Introduction 1.1. In the current climate many businesses are faced with the difficult decision as to whether they can continue with their operations at this unprecedented time; none more so than those who operate...

Episode 4 - COVID-19 webinar - When does a pandemic crisis spell disaster? - May 4 Listen to the replay of Eversheds Sutherland's episode 4 podcast providing guidance on at what stage does the pandemic crisis spell disaster. Reputations will be ma...

HEALTH AND SAFETY In the courts - cameras to broadcast from the Crown Court for the first time The government has announced new legislation which will permit the sentencing remarks of High Court and senior judges in certain criminal cases to be film...

There have been many examples of high profile health and safety incidents in recent years, including major rail disasters, the serious incident at Alton Towers and of course the tragedy at Grenfell Tower. These have rightly received high profile, wi...

ENVIRONMENT Long Awaited Environment Bill Back in Parliament The UK Environment Bill seeks to deliver “the most ambitious environmental programme of any country on earth” by setting a “gold standard” for environmental protect...

In June 2019, an FSA report on the approach to regulatory enforcement and sanctions acknowledged that enforcement of food law has historically relied upon criminal sanctions. Whilst the report stated that “in relation to some lower level failu...

  HEALTH & SAFETY So what now? Where low occupancy poses water-borne risks Most organisations during this pandemic have rightly focused on the health and safety of employees and the general public in tackling the spread of the virus. Whilst...

“We want to ensure that these crimes don’t pay.” Michael Caplan QC, Sentencing Council Member In an era where price fixing and anti-competitive practices attract fines measured in billions, the disparity associated with sentencin...

New rules, no problem. At least, that’s the case for a Henderson cafe preparing to host customers for the first time in nearly two months. Magnolia Magat already was set on implementing Centers for Disease Control and Prevention-driven changes to her Truffles N’ Bacon Cafe, 8872 S. Eastern Ave., before the governor told her what she must to do open her business on Saturday. If she doesn’t comply with mandated social distancing, face coverings for her employees and limiting occupancy, she is at risk of a verbal warning, citation and business license suspension. But that likely won’t concern Magat, whose measures for her own cafe will be more stringent than those...

The market for wearable tech is huge and growing, driven by new wellness applications and improved connectivity. Add to that the increasing number of new IoT devices and applications in the home, workplace and industry, and the opportunities both fo...

HSE’s Business plan With major structural changes to the UK economy expected post Brexit, now is a time for the Health and Safety Executive (HSE) to reflect on its business plan and the associated implications.  The HSE will be keen to de...

Millions of Asia’s informal workers – such as vendors, day laborers, and others – are left out of national pension systems. Here’s what we can do to help them in their later years.

Health and safety on the jobsite involves more than simply enforcing rules and regulations. A culture of prevention, as well as innovative digital solutions, are needed to keep workers alive and healthy.

Past financial crises have demonstrated how adequate financial safety net arrangements—globally, regionally, and nationally—are vital to safeguarding financial stability.

In recent years, particularly in many developing countries, road developers have failed to give sufficient consideration to road safety features in the design and construction of highways. As a result, these roads have become more deadly.

"I was inspired by my sense of fashion," Ward said. "It was my first home and I wanted my home decor to represent me and my personality as much as possible. I have a lot of space so I could create different aspects of my life into each room."

Islamabad : The Ministry of Human Rights on Friday issued guidelines to create public awareness on the protection of mental and physical health of children and their online safety during COVID-19 lockdown days.According to guidelines issued on different media forums, parents are advised to engage...

Microchip Simplifies Functional Safety Requirements with MPLAB TÜV SÜD-certified Tools

New Functional Safety Ready AVR® DA Microcontroller Family Enables Real-Time Control, Connectivity and HMI Applications

Functional Safety Manual and FMEDA Access for dsPIC33C Family

MPLAB XC Compiler Functional Safety Manual

STAMFORD, CT – September 14, 2016 –HARMAN International Industries, Incorporated (NYSE:HAR), the premier connected technologies company for automotive, consumer and enterprise markets, announced it will showcase additional sensor functionality for the...

A decade ago, Johan Rockström identified the limits to Earth's life support systems. From chemical pollution to climate change, we're veering into the danger zone - so why is he (cautiously) optimistic about the future?

When it comes to electric vehicles, there’s no denying the multitude of benefits for manufacturers, consumers, and the environment – from reduced emissions to lower fuel costs, increased efficiency, and lower noise pollution. These benefits continue to...

Analysts are forecasting that 250 million connected cars will be on the road as early as 2020. At the same time, the magnitude of data transfers between these cars and their environment will only continue to grow. The automotive industry is at a tipping...

Title: FDA Targets Safety Problems With Infusion Drug Pumps
Category: Health News
Created: 4/23/2010 4:10:00 PM
Last Editorial Review: 4/26/2010 12:00:00 AM

Title: Better Ways Needed to Track Drug Safety: Report
Category: Health News
Created: 5/1/2012 2:05:00 PM
Last Editorial Review: 5/2/2012 12:00:00 AM

Title: Let Safety Bloom in Your Garden This Season
Category: Health News
Created: 4/22/2016 12:00:00 AM
Last Editorial Review: 4/25/2016 12:00:00 AM

Title: Contraception Safety Program for Acne Drug Failing in Canada
Category: Health News
Created: 4/25/2016 12:00:00 AM
Last Editorial Review: 4/26/2016 12:00:00 AM

Title: When Grandparents Raise Grandkids, Are They Up to Date on Child Safety?
Category: Health News
Created: 5/4/2017 12:00:00 AM
Last Editorial Review: 5/4/2017 12:00:00 AM

Title: Ecstasy May Help Some PTSD Sufferers, but Safety Issues Remain
Category: Health News
Created: 5/1/2018 12:00:00 AM
Last Editorial Review: 5/2/2018 12:00:00 AM

Title: Many Smokers Switch to Vaping While Pregnant, But Safety Issues Remain
Category: Health News
Created: 4/29/2019 12:00:00 AM
Last Editorial Review: 4/30/2019 12:00:00 AM

Title: Study Confirms Safety, Effectiveness of Children's Vaccines
Category: Health News
Created: 4/23/2020 12:00:00 AM
Last Editorial Review: 4/24/2020 12:00:00 AM

Causal analysis is a core function of safety programs. Although established protocols exist for conducting root cause analysis for serious safety events, there is limited guidance for apparent cause analysis (ACA) in health care. At our institution, through a novel facilitated ACA approach, we aim to improve safety culture and provide a clear approach to address precursor safety events and near-miss safety events. We define facilitated ACA as limited investigation (scope and duration) of a safety event that resulted in little to no harm. These investigations require fewer resources and focus on preventive strategies. Our facilitated ACA model, with an operational algorithm and structured process, was developed and implemented at our tertiary-care, freestanding, urban pediatric hospital in 2018. Sixty-four ACAs were completed, and 83% were identified with the algorithm. Process measures, including time from event reporting to ACA launch (median 3 days; interquartile range 2–6 days), are tracked. Patient safety consultants averaged 5 hours to complete a facilitated ACA. A median of 3 disciplines or departments participated in each facilitated ACA. Through an iterative process, we implemented a structured process for facilitated ACA, and the model’s strength includes (1) right event, (2) right team, (3) right analysis, and (4) right action plans. This novel facilitated ACA model may support organizational cause analysis and improve safety culture with higher-reliability processes.

Background

Canagliflozin reduced renal and cardiovascular events in people with type 2 diabetes in the CREDENCE trial. We assessed efficacy and safety of canagliflozin by initial estimated glomerular filtration rate (eGFR).

Inhaled corticosteroid/long-acting β₂-agonist combination therapy is a recommended treatment option for patients with chronic obstructive pulmonary disease (COPD) and increased exacerbation risk, particularly those with elevated blood eosinophil levels. SOPHOS (NCT02727660) evaluated the efficacy and safety of two doses of budesonide/formoterol fumarate dihydrate metered dose inhaler (BFF MDI) versus formoterol fumarate dihydrate (FF) MDI, each delivered using co-suspension delivery technology, in patients with moderate-to-very severe COPD and a history of exacerbations.

In this phase 3, randomised, double-blind, parallel-group, 12–52-week, variable length study, patients received twice-daily BFF MDI 320/10 µg or 160/10 µg, or FF MDI 10 µg. The primary endpoint was change from baseline in morning pre-dose trough forced expiratory volume in 1 s (FEV₁) at week 12. Secondary and other endpoints included assessments of moderate/severe COPD exacerbations and safety.

The primary analysis (modified intent-to-treat) population included 1843 patients (BFF MDI 320/10 µg, n=619; BFF MDI 160/10 µg, n=617; and FF MDI, n=607). BFF MDI 320/10 µg and 160/10 µg improved morning pre-dose trough FEV₁ at week 12 versus FF MDI (least squares mean differences 34 mL [p=0.0081] and 32 mL [p=0.0134], respectively), increased time to first exacerbation (hazard ratios 0.827 [p=0.0441] and 0.803 [p=0.0198], respectively) and reduced exacerbation rate (rate ratios 0.67 [p=0.0001] and 0.71 [p=0.0010], respectively). Lung function and exacerbation benefits were driven by patients with blood eosinophil counts ≥150 cells·mm^–3. The incidence of adverse events was similar, and pneumonia rates were low (≤2.4%) across treatments.

SOPHOS demonstrated the efficacy and tolerability of BFF MDI 320/10 µg and 160/10 µg in patients with moderate-to-very severe COPD at increased risk of exacerbations.

OBJECTIVE

Most individuals with type 2 diabetes also have obesity, and treatment with some diabetes medications, including insulin, can cause further weight gain. No approved chronic weight management medications have been prospectively investigated in individuals with overweight or obesity and insulin-treated type 2 diabetes. The primary objective of this study was to assess the effect of liraglutide 3.0 mg versus placebo on weight loss in this population.