iq

Intermixed Dimethyl-Sulfoxide-Based Nonadhesive Liquid Embolic Agents Delivered Serially via the Same Microcatheter for Cerebral AVM Treatment [INTERVENTIONAL]

BACKGROUND AND PURPOSE:

Conventional nonadhesive liquid embolic agents currently are the criterion standard for endovascular embolization of cerebral AVMs. However, inadequate distal penetration into the nidus and unstable proximal plug formation are the major limitations of this approach and of the currently available embolic materials. The aim of this study was to evaluate the hypothetic efficacy of combining liquid embolic agents with different properties and viscosities for use in endovascular embolization of cerebral AVMs.

MATERIALS AND METHODS:

From March 2018 to March 2019, sixteen patients with cerebral AVMs (12 women, 4 men; age range, 33–61 years) underwent endovascular embolization with combined liquid embolic agents delivered serially via a single microcatheter. The procedure consists of initial embolization with PHIL 30%, followed by Menox 18 through the same microcatheter. According to the Spetzler-Martin scale, 11 (68.75%) AVMs were grades I–II, 4 (25%) were grade III, and 1 (6.25%) was grade IV. Angiographic, technical, and clinical outcomes were analyzed independently.

RESULTS:

Combined PHIL and Menox embolization through the same microcatheter via 21 pedicles was performed in these 16 patients. Once the length of the reflux reached approximately 2 cm, PHIL 30% was switched to Menox 18. Antegrade flow and distal penetration of the serially applied liquid embolic agents were observed in all 16 cases. The ability to completely control the flow of the materials and avoid any dangerous proximal reflux was noted in all performed embolizations. The estimated average size reduction of the treated AVMs was 85%, ranging from 50% to 100%. Complete embolization was achieved in 10/16 or 62.5% of the cases. There was no procedure-related complication during or after the embolization. No mortality or postprocedural clinical worsening was seen. Clinical success and complete obliteration were confirmed with at least 1 follow-up angiography in 10/16 patients.

CONCLUSIONS:

Serial delivery of nonadhesive liquid embolic agents via the same microcatheter was safe and effective in our study and may be a potential technique for routine AVM treatment. However, further investigations are required to validate the safety and the efficacy of the method.




iq

THE OPERA RESIDENCE AND ITS PRIME UNIQUE LOCATION AT THUTHIEM NEW URBAN - +84911 130 135

Proudly located at a unique position that no project has - adjacent to the Opera House, another masterpiece of The Metropole Thu Thiem project named The Opera Residence is ready for REFUNDABLE BOOKING to reserve the chance at the official launch this Q3. This third masterpiece of...




iq

SAIGON GARDEN RIVERSIDE VILLAGE THE UNIQUE PRODUCT IN DISTRICT 9, PRICE FROM 21 million VND/M

-Location: Long Binh ward, district 9, HCM city. -Price only from 21 million VND/m2. -The house is in the heart of nature, a peaceful place for yourself. -The unique masterpiece in Saigon. ----- HIGHLIGHTS -Landscape channel leading to each villa. -Tennis court and children's pla...




iq

3 options for safe investment when liquidity of land lot segment drops

Many investors have shifted their money into real estate for lease or short-term deposit in banks as the liquidity of land lot segment has declined sharply.




iq

Don't miss: Emotional veg, antique innovations and spooky maths

This week, hide behind the sofa from mind-altering plants, listen and learn from technologies past and find out how the world is underpinned by numbers




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Liquid metal that floats on water could make transformable robots

A lightweight liquid metal alloy that is less dense than water could be used to make exoskeletons and transformable flexible robots




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Liquid iron rain spotted on super-heated exoplanet WASP-76b

Exoplanet WASP-76b, which is about 390 light years from the solar system, has a strange iron signature in its atmosphere, suggesting the metal is raining down on the planet's night side




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Unique 3D-images reveal the architecture of nerve fibers

Researchers have used synchrotron light to study what happens to the nerves in diabetes. The technique shows the 3D-structure of nerve fibers in very high resolution.




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Selah and the Spades review – teen cliques drama balances satire and surrealism

This uncanny story of preppy drug dealers has a touch of Heathers and a bit of Bret Easton Ellis, and an intriguing take on what high school is really like

Tayarisha Poe, like her partial namesake, has a gift for the uncanny. She is the photographer and film-maker behind this feature debut, which began as an online multimedia project and was developed as a conventional movie through the Sundance screenwriters and directors labs. What has emerged is an intriguing, opaque, tonally elusive story that seems weirdly unfinished. It is set in a privileged high school – a world of ivy-covered stone buildings and shady quadrangles where rich kids are separated into malign and mutually hostile cliques. It has a touch of Donna Tartt and Bret Easton Ellis, a hint of Heathers and a bit of the elegant, disdainful satire of Dear White People.

Somehow, though, it is odder, more stylised and contrived, always holding out the possibility that it is set in the future, or in an alternative present on some other planet, or inside the head of one of its characters who is having a disturbing dream – the kind that ends just as it is about to give up its meaning. Right until the closing credits, I half-expected the face of each person on screen to flip upwards, revealing a Stepford-like set of dials.

Continue reading...




iq

'Heartbroken' Sadiq Khan confirms 21 London transport workers have now died from Covid-19

Follow our live Covid-19 updates HERE




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Sadiq Khan reiterates calls for face masks to be worn amid Covid-19 outbreak as Grant Shapps insists it's 'not right time' to change advice

Read our live coronavirus updates HERE




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Sadiq Khan announces free bus travel in London to protect drivers from coronavirus

Follow our live coronavirus updates HERE Coronavirus: The symptoms




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London's air quality has 'dramatically improved' amid coronavirus lockdown, says Sadiq Khan

London's air quality has "dramatically improved" due to the drop in traffic amid the coronavirus lockdown, Sadiq Khan has said.




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What is an 'awake' operation? The technique being increasingly used during the coronavirus pandemic

FULL STORY: Patients kept awake during cancer surgery to protect them from coronavirus




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Sadiq Khan 'really worried' about capital's transport after lockdown easing

The Mayor of London warned against a 'big bang' of lifting lockdown measures




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Union demands Sadiq Khan make travel free for Tube cleaners who are 'integral' to capital's coronavirus response

Union bosses have written to Sadiq Khan to demand a reversal of Transport for London's "disgraceful" decision to deny free travel to London Underground's cleaners.




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Sadiq Khan urges Londoners not to relax 'monumental effort' to beat coronavirus over Bank Holiday weekend

Mayor Sadiq Khan today made an urgent appeal to Londoners not to relax their "monumental effort" to beat coronavirus as the death toll in the capital's hospitals rose to 5,414.




iq

Archaeologists Have a Lot of Dates Wrong for North American Indigenous History — But Are Using New Techniques to Get It Right

Modern dating techniques are providing new time frames for indigenous settlements in Northeast North America, free from the Eurocentric bias that previously led to incorrect assumptions.




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Antiques Roadshow: Guitar once owned by George Harrison and John Lennon valued at up to £400,000

Show's expert called it 'by far the most expensive thing [he's] ever seen in 25 years'




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James Bond: Goldfinger hat valued at £30,000 on Antiques Roadshow

The bowler hat was used by Goldfinger's henchman Oddjob




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National Password Day project: A unique password for every website you go to

We need to have a different strong, password for every website we go to. Password managers like Dashlane and 1Password help us remember them.

      




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At-home boxing workouts: pro tips to help you tweak your technique without a bag

No eqiupment, no problem




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Barcelona coach Quique Setien dreams of 'showing Champions League trophy to the cows' in his village

Barcelona coach Quique Setien has said he dreams of winning the Champions League and showing the trophy to the cows in his village.




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Lionel Messi will finish his career at Barcelona, says coach Quique Setien

Barcelona coach Quique Setien says he is sure Lionel Messi will finish his career at Camp Nou.




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Philippe Coutinho to Chelsea: Barcelona coach Quique Setien delivers transfer update

Barcelona coach Quique Setien believes Philippe Coutinho is a 'great player' and says he is 'counting on' the 27-year-old for next season.




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Lautaro Martinez to Barcelona: Head coach Quique Setien lifts lid on chances of signing the Inter Milan star

Barcelona head coach Quique Setien has lifted the lid on his side's pursuit of Inter Milan star Lautaro Martinez.




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Barcelona head coach Quique Setien reveals 'huge incentive' for Lautaro Martinez to complete transfer

Barcelona head coach Quique Setien has labelled Lautaro Martinez a "great footballer" and believes the chance to play alongside Lionel Messi is a huge incentive for the Inter Milan striker.




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Barcelona boss Quique Setien dons mask and gloves as Lionel Messi and fellow stars return to training

Barcelona's players returned to training on Friday after medical tests conducted earlier this week.




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How 'Animal Crossing' was built to be ubiquitous in coronavirus time — back in 2001

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Un retour des Nordiques pourrait être favorisé par la pandémie, selon Pierre Karl Péladeau

Selon Pierre Karl Péladeau, la crise du coronavirus pourrait permettre d’établir les bases du retour d’une équipe de hockey professionnelle à Québec.




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Man Ki Baat: Ramayan Breaks Record, Kim Jong-un Is Alive & Liquor Stores Finally Open



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7 Successful Companies With Unique Concepts That Ratan Tata Has Invested In




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YouTuber CarryMinati’s Roast Destroys TikToker Amir Siddiqui & Desi Twitter Says ‘Boht Hard’




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India develops unique model to hit enemy targets without positioning error

New Delhi (Sputnik) Apr 22, 2020
Due to the unavailability of a reliable model to predict the electron density of the ionosphere, navigation errors remain, creating technological hurdles. A new model developed by Indian researchers has potential applications in calculating these Global Navigation Satellite System (GNSS) positioning errors. In a major development that could have a wider impact, ranging from accurate aiming




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Le PLQ plaide pour l’intégration des services psychologiques dans le régime public

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Pascal Dupuis s'implique avec les Cataractes

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Jeux olympiques de Montréal: un projet grandiose qui a 50 ans

Fierté collective ou tache dans l’histoire, les Québécois débattent encore sur leur héritage des Jeux olympiques de 1976 à Montréal.




iq

QUB Musique: les coups de cœur de Yann Perreau

Porte-parole de QUB Musique avec Alex Nevsky et Guylaine Tanguay, Yann Perreau passe son confinement en famille à son chalet de Lanaudière.




iq

Chez QUB Musique, Offenbach côtoiera les Rolling Stones

En quoi ce nouveau service d’écoute musicale en continu va se démarquer de ses gigantesques rivaux sur le marché. Explications en cinq points.




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5 films et séries d’action à visionner pour mettre du piquant dans votre journée

Notre sélection des sorties du mois sur Club illico




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Les maladies chroniques et la COVID-19

Les études réalisées jusqu’à maintenant montrent qu’une proportion des patients sont affectés par une condition de santé précaire.




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Five sisters, one dream: Meet regional Victoria's 'unique' football-playing quintet

Five sisters make up a quarter of their tiny town's under-16s Aussie Rules team. They can't compete right now, but they are all determined to break into the professional ranks one day.



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Five years of horrific pain made Monique question her own sanity, until she was finally diagnosed

This swimmer spent years battling endometriosis, an insidious enemy within her own body that consumed her with crippling pain. The fact that most coaches in women's sport are men also didn't help, she says.




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New Fluorescence Microscopy Technique for Nanostructure Visualization Within Cells

Researchers at Purdue University have developed a new technique to dramatically enhance the resolution achievable when imaging intracellular structures with super-resolution fluorescence microscopy. The technique uses the distortions created by a specimen to pinpoint the location of individual molecules, and thereby infer the location of intracellular structures. The technique could be particularly useful in studying […]





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UK Government focus on strengthening clinical research amidst unique challenges of Brexit

The Association of Clinical Research Organizations (ACRO) convenes discussion series that seeks to advance an industry with important health and economic impacts...




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Dr. Cynthia Verst of IQVIA Elected 2019 ACRO Chair

Washington DC – The Association of Clinical Research Organizations (ACRO) is pleased to announce that its Board of Directors has elected Dr. Cynthia Verst,...




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ACRO offers unique insights on risk-based monitoring of clinical trials, calls for adoption of RBM as a best practice

Following meetings with then-Commissioner Scott Gottlieb and senior leadership from the Center for Drug Evaluation and Research on the role of CROs and technology companies in designing and implementing risk-based monitoring (RBM) of clinical trials, ACRO this week submitted extensive comments on recent FDA Guidance.Increasing the use of innovative RBM technologies helps make clinical trials safer, more efficient and higher quality. ACRO’s comments offer unique insights into the recent expansion of RBM implementation and call for further increasing the use of these oversight technologies.




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Bristol Myers Squibb's blood thinner Eliquis soars on COVID-19 demand, but Opdivo could suffer: execs

Bristol Myers Squibb CEO Giovanni Caforio credited COVID-19-related stocking for high sales of some products in the first quarter, including Eliquis, a blood thinner that's being snapped up to reduce clotting risk in patients with the virus. But the pandemic has limited access to oncology clinics and other non-COVID-19 services, raising challenges that could impact sales later this year.




iq

Attorney General Eric Holder Speaks at the Inaugural Justice Revius O. Ortique Jr. Lecture on Law and Society at Dillard University

"Tonight, it is clear that the spirit of justice that motivated Justice Ortique still burns brightly," said Attorney General Holder.