In addition to the service outlined below, starting on Thursday, March 19, Route 301 will add the weekday roundtrip leaving Wilmington at 4:20 AM, arriving in Dover at 5:42 AM; and then leaving Dover at 6:00 AM, arriving in Wilmington at 7:41 AM. Route 303 will be operating the weekday schedule. In Sussex County, Route 206 will operate on the normal weekday schedule.

DART public transit services are operating on the following reduced service schedule until further notice. On weekdays, regular fixed route services are operating on a Saturday service schedule statewide, with additional service on Routes 15, 18, 43 and 301. DART’s regularly scheduled weekend service will operate normal service levels. For specifics, please visit https://www.DartFirstState.com.

Statewide Paratransit services will continue to operate normal hours, as will the Reservations Call Center.

Due to the presence of Coronavirus (COVID-19) in Delaware, business closures, reductions in staffing and lower ridership levels, effective Wednesday, March 18, DART public transit services will operate on the following reduced service schedule until further notice. On weekdays, regular fixed route services will operate on a Saturday service schedule statewide, with additional service on […]

The Delaware Department of Insurance today released a list of consumer-friendly automobile insurer actions that are being implemented due to reduced vehicle use throughout the COVID-19 pandemic. As filed with the department, these actions represent millions of dollars being returned to or saved by policyholders throughout the state. The following list may not be inclusive […]

In February 2020, international passenger capacity reduced by 13 per cent, mainly related to traffic from/to States experiencing an early outbreak and States deeply interconnected to China.

Weeks of lockdown in the country to fight coronavirus may have reduced greenhouse gas emissions enabling people to breathe cleaner air and feast on blue skies, but it is only a temporary phase and will not benefit the environment in the long run.

The Government has today announced, just as predicted, a fall in RPI-linked compensation limits. The maximum compensatory award for unfair dismissal will decrease from £66,200 to £65,300 for effective dates ...

Dunbar v Virgo Consultancy Services Limited [2019] EWHC B12 (Costs) Mr Dunbar instructed law firm Virgo Consultancy to assist a Greek legal team with a defence of his son, in a serious criminal offences action brought against him in Crete. A deposit...

The Smith Commission has today revealed that control of Employment Tribunals in Scotland is to be devolved to the Scottish Parliament.  The move will mean Scotland will be able to decide the level at which fees are set for claims made in Scotla...

There are no signs North Korean leader Kim Jong-un received heart surgery when he disappeared from state media for three weeks, but he reduced public activity due to coronavirus concerns, South Korean lawmakers briefed by the spy agency said on Wednesday.Kim attended the completion of a fertiliser plant, North Korea’s official media said on Saturday, the first report of his appearing in public since April 11.His absence fuelled a flurry of speculation about his health and whereabouts, with a…

Czech Development Agency

While as late as 1990 the WHO reported 116 deaths for every 1,000 births in Cambodia, the situation has now improved fourfold. This is credited to a Czech Development Agency project through which health care equipment and neonatal tools, including incubators, were provided to the Pediatric Hospital in Phnom Penh.

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Title: FDA OKs Farxiga for Heart Failure With Reduced Ejection Fraction
Category: Health News
Created: 5/6/2020 12:00:00 AM
Last Editorial Review: 5/7/2020 12:00:00 AM

Synesthesia is a neurologic trait in which specific inducers, such as sounds, automatically elicit additional idiosyncratic percepts, such as color (thus “colored hearing”). One explanation for this trait—and the one tested here—is that synesthesia results from unusually weak pruning of cortical synaptic hyperconnectivity during early perceptual development. We tested the...

Human activities and population growth have increased the natural burden of reactive nitrogen (N) in the environment. Excessive N deposition on Earth’s surface leads to adverse feedbacks on ecosystems and humans. Similar to that of air pollution, emission control is recognized as an efficient means to control acid deposition. Control...

Andreas Nord, Arne Hegemann, and Lars P. Folkow

Animals in seasonal environments must prudently manage energy expenditure to survive the winter. This may be achieved through reductions in the allocation of energy for various purposes (e.g. thermoregulation, locomotion, etc.). We studied whether such trade-offs also include suppression of the innate immune response, by subjecting captive male Svalbard ptarmigan (Lagopus muta hyperborea) to bacterial lipopolysaccharide (LPS) during exposure to either mild temperature (0°C) or cold snaps (acute exposure to –20°C), in constant winter darkness when birds were in energy-conserving mode, and in constant daylight in spring. The innate immune response was mostly unaffected by temperature. However, energy expenditure was below baseline when birds were immune challenged in winter, but significantly above baseline in spring. This suggests that the energetic component of the innate immune response was reduced in winter, possibly contributing to energy conservation. Immunological parameters decreased (agglutination, lysis, bacteriostatic capacity) or did not change (haptoglobin/PIT54) after the challenge, and behavioural modifications (anorexia, mass loss) were lengthy (9 days). While we did not study the mechanisms explaining these weak, or slow, responses, it is tempting to speculate they may reflect the consequences of having evolved in an environment where pathogen transmission rate is presumably low for most of the year. This is an important consideration if climate change and increased exploitation of the Arctic would alter pathogen communities at a pace outwith counter-adaption in wildlife.

In 2016, the proportion of Neisseria gonorrhoeae isolates with reduced susceptibility to azithromycin rose to 3.6%. A phylogenetic analysis of 334 N. gonorrhoeae isolates collected in 2016 revealed a single, geographically diverse lineage of isolates with MICs of 2 to 16 μg/ml that carried a mosaic-like mtr locus, whereas the majority of isolates with MICs of ≥16 μg/ml appeared sporadically and carried 23S rRNA mutations. Continued molecular surveillance of N. gonorrhoeae isolates will identify new resistance mechanisms.

A drug used to treat Ebola patients has shown "very promising" early results in a trial of people admitted to hospital with coronavirus.

Fewer people would have died from coronavirus in the UK if the country had greater testing capacity sooner, Transport Secretary Grant Shapps has said.

The rate of transmission of coronavirus is "much reduced" and the death toll is steadily falling, the Downing Street press conference has heard.

Damien Comolli, the former Liverpool and Tottenham director of football, believes the transfer window will be very different next time around due to the coronavirus pandemic.

Jose Mourinho is expecting to be limited to free agents and swap deals in the next transfer window, as the top-flight prepares for a drastically changed financial outlook brought on by the coronavirus pandemic.

Farxiga is the first sodium glucose co-transporter 2 inhibitor cleared by the FDA to treat heart failure with reduced ejection fraction

The FDA has moved to approve an oral tablet formulation of AstraZeneca’s Farxiga (dapagliflozin) to reduce the risk of cardiovascular death and hospitalisation in adult patients with New York Heart Association’s functional class II-IV heart failure with reduced ejection fraction.

Attorney General Eric Holder announced Tuesday that the Justice Department would formally support a proposal under consideration by the U.S. Sentencing Commission to allow certain individuals serving time in federal prison for nonviolent drug offenses to be eligible for reduced sentences.

Major League Baseball will hold a five-round draft in June, a big reduction from the usual 40 rounds. Many Southland players are expected to be taken.

Environmentalists feel that carbon emissions may have reduced drastically but are likely to go back to the pre-corona levels in a few weeks' time, once the virus threat mitigates.

The family of Michael Schumacher have confirmed media reports he is slowly being brought out of his medically induced coma

A new study suggests we look to the past for guidance on how to cope going forward.

They've done more than just change out a few lightbulbs to meet this goal, and in fact this is only the beginning. Their ultimate goal is to reduce Yale University's greenhouse gas emissions to 43% below 2005 levels by the year 2020. Sure, you say, but

Eldar Sætre, CEO of Equinor, discusses the company's first-quarter earnings.

Senior citizens can preserve muscle mass by consuming more protein at breakfast or lunchtime. The body's mechanisms for producing new muscle require

Traffic pollution in UK is reducing thanks to the COVID-19 lockdown. But more urban ozone - a dangerous air pollutant which can cause airway inflammation

To end AIDS epidemic by 2030 according to World Health Organization goals, tuberculosis must also be reduced, said Forum of International Respiratory Societies (FIRS).

Traffic pollution in UK is reducing thanks to the COVID-19 lockdown.

Among adults with mental health disorders, losing Medicaid coverage was found to lead to lasting reductions in overall healthcare use and in outpatients

Checking children affected from blunt trauma for CSI (cervical spine injury) risk factors could cut unnecessary computed tomography (CT) scans and radiation exposure by half.

The Indian economy is expanding at a fast pace, boosting living standards and reducing poverty nationwide. Further reforms are now necessary to maintain strong growth and ensure that all Indians benefit from it, according to a new report from the OECD.

Radamel Falcao has been reduced to tears by his Manchester United nightmare, according to his former agent. The 29-year-old has also expressed fear of an injury playing for the Under 21s.

David Davis, the former Brexit Secretary and ex-SAS reservist, relished his reputation as the hard man of British politics. But he cannot help but cry when he thinks of his granddaughter Chloe.

Count the previously buoyant European Tour as another branch of sport staring into a financial black hole owing to the effects of coronavirus.

ITV bosses are thought to be discussing how to keep the shows running in case cast members get struck down by the pandemic.

EXCLUSIVE BY WILL KELLEHER AND NIK SIMON: The Premiership' s £7million salary cap could be reduced to mitigate the impact of the coronavirus.

The president laid flowers at the tomb of the unknown soldier outside the Kremlin in Moscow.

Jurgen Klopp has admitted the challenge of preparing Liverpool to face Atletico Madrid was like nothing he has ever experienced as the Coronavirus pandemic swept the Spanish capital.

Mayor Sadiq Khan said public transport should only be used for critical workers in a bid to stop the spread of coronavirus. But the reduced transport services have only exacerbated the situation.

The former Paralympic athlete, 31, had asked South Africa's Constitutional Court to review the sentence, which was increased from six to 15 years in November.

Last year teams agreed to a budget cap of 175million US dollars (£142million) for 2021 but there have been suggestions that could be cut further.

Brisbane mother-of-three Violet, has been forced to provide for her family after her husband lost his job and was heartbroken to hear her rent would not be reduced.

Demolition work on the house — at Elstree Studios in Borehamwood — Hertfordshire, kicked off just two weeks after the November finale, which saw Cameron Cole crowned as the victor.