Half of the residents of troubled Gold Coast nursing home Earle Haven were being physically restrained, and 71 per cent received medical restraint, in the weeks before it abruptly closed its doors last month, the aged care Royal Commission hears.

The Tait twins, Sara and Kristen, had a tough start. One was born with spina bifida, the other with two large holes in her heart. But that hasn't stopped either of them from becoming high achievers.

For the first time two overall winners have won the prestigious David Malin Awards which honours the best in Australian astrophotography.

(United States Ninth Circuit) - Held that a health insurance company did not violate the Affordable Care Act's Medical Loss Ratio provision, which requires an insurer to pay a rebate to enrollees if it uses less than 80 percent of the revenue it takes in to pay medical claims. Affirmed a dismissal, in this proposed class action lawsuit brought by health insurance enrollees.

(United States Seventh Circuit) - Held that an insurance company was not liable for bad faith for failing to settle a medical malpractice claim for the policy limit. Affirmed a JMOL against the claims of an outpatient surgical center.

(United States Federal Circuit) - Affirming a Patent Trial and Appeal Board determination that patents relating to systems for performing marine seismic surveying were unpatentable because they made no error justifying the disturbance of their obviousness decisions.

(United States Supreme Court) - Reversed and remanded. WesternGeco owns a patent for a system to survey the ocean floor and they believed that a competing system owned by ION infringed on their patent. WesternGeco sued. The jury found ION liable and awarded WesternGeco damages including lost profit damages. ION argued that the lost profit damages was not allowed and the appellate court agreed with them. The US Supreme Court disagreed and reversed and remanded the decision stating that lost profits for a domestic patent was permissible under the Patent Act.

(United States Fifth Circuit) - Held that a university-affiliated medical practice must return $8 million to the federal agency that administers Medicare. The medical practice's test of a new care management model (a Medicare demonstration project) did not achieve the expected cost savings. Upheld an administrative order.

Physician and Rep. Gregory Murphy said on SiriusXM’s Breitbart News Daily that “draconian” lockdowns are no longer needed in many places.

The latest developments in the coronavirus pandemic from weekend across the region. We check in with the mayors of Truckee and Chico on how their cities are managing, and a local photographer offers a window into the lives of her neighbors.

From Leah Wing: Dear Colleagues, The National Center for Technology and Dispute Resolution is happy to announce the unveiling of a newly updated extensive Online Dispute Resolution (ODR) bibliography which is available on our website and here. It is wonderful to see so many new partners from the courts, alternative dispute resolution, and many other … Continue reading Extensive ODR Bibliography →

The sheriff's office is telling hikers not to gather in groups large than four.

“Laughter is often the best medicine.”

Watch the comedian in "Boomerang" this week.

One of the most fascinating things about planet Earth is the way that life shapes the Earth and the Earth shapes life. We only have to look back to the Great Oxygenation Event (GOE) of 2.4 billion years ago to see how lifeforms have shaped the Earth. In that event, phytoplanktons called cyanobacteria pumped the …

Continue reading "New Data Show How Phytoplankton Pumps Carbon Out of the Atmosphere at an Enormous Scale"

The post New Data Show How Phytoplankton Pumps Carbon Out of the Atmosphere at an Enormous Scale appeared first on Universe Today.

Giant-scale physics experiments are increasingly reliant on big data and complex algorithms fed into powerful computers, and managing this multiplying mass of data presents its own unique challenges. To better prepare for this data deluge posed by next-generation upgrades and new experiments, physicists are turning to the fledgling field of quantum computing.

Facioscapulohumeral muscular dystrophy (FSHD) results from expression of the full-length double homeobox 4 (DUX4-FL) retrogene in skeletal muscle. However, even in cases of severe FSHD the presence of DUX4 is barely detectable. In this issue of the JCI, Bosnakovski et al. used an inducible, muscle-specific human DUX4 to reproduce the low-level, sporadic DUX4 expression of human FSHD muscle as well the myopathology seen in human FSHD disease. Notably, dysregulated fibroadipogenic progenitors accumulated in affected muscles, thus providing a mechanism for the replacement of muscle by fibrosis and fat.

Lamin A is a component of the inner nuclear membrane that, together with epigenetic factors, organizes the genome in higher order structures required for transcriptional control. Mutations in the lamin A/C gene cause several diseases belonging to the class of laminopathies, including muscular dystrophies. Nevertheless, molecular mechanisms involved in the pathogenesis of lamin A–dependent dystrophies are still largely unknown. The polycomb group (PcG) of proteins are epigenetic repressors and lamin A interactors, primarily involved in the maintenance of cell identity. Using a murine model of Emery-Dreifuss muscular dystrophy (EDMD), we show here that lamin A loss deregulated PcG positioning in muscle satellite stem cells, leading to derepression of non–muscle-specific genes and p16INK4a, a senescence driver encoded in the Cdkn2a locus. This aberrant transcriptional program caused impairment in self-renewal, loss of cell identity, and premature exhaustion of the quiescent satellite cell pool. Genetic ablation of the Cdkn2a locus restored muscle stem cell properties in lamin A/C–null dystrophic mice. Our findings establish a direct link between lamin A and PcG epigenetic silencing and indicate that lamin A–dependent muscular dystrophy can be ascribed to intrinsic epigenetic dysfunctions of muscle stem cells.

[Image: An example of gravitational lens effects, via Wikipedia.] Over at WIRED, Daniel Oberhaus, author of the recent book Extraterrestrial Languages, takes a look at some proposals from NASA’s Innovative Advanced Concept (NIAC) program. “Among this year’s NIAC grants,” Oberhaus writes, “are proposals to turn a lunar crater into a giant radio dish, to develop … Continue reading "Gravitational Lensing, Interstellar Cinematography, and the Future of Magical Warfare in Space"

The actor behind Luke Skywalker takes StarWars.com on a journey through filming the Star Wars sequel in time for the 40th anniversary of its release.

PSY is doing all those moves in a mock-turtleneck and with a belt on. Clearly that's enough proof that PSY is talented K-Pop robot sent to inspire us all.

Astrophysical jets are flows of matter that moves at relativistic speed. They are opportunity to see length contraction in action. An astrophysical jet is analyzed to explain the length contraction effect. Astrophysical jets are ejected from compact objects such as black holes. https://en.wikipedia.org/wiki/Astrophysical_jet#/media/File:M87_jet.jpg is a photograph of the jet ejected by the supermassive black hole...

TROLLING PHYSICS Existed in comics way before the internet

John Sullivan, deputy chief of the Worcester Fire Department/vice chair of the IAFC health and safety section, discusses why it's so important for firefighters to get physical exams each year.  The average age of a first heart attack for the general

As of May 5, more than 3.5 million people in 215 countries around the world have been infected with the novel coronavirus, according to the World Health Organization. While the world continues to socially distance, designers and creatives are beginning to imagine different ways to protect people from the virus; case in point, this futuristic bubble shield by DesignLibero.[...]

The post Color Photography Exercises to Help You Improve Your Skills appeared first on Digital Photography School. It was authored by Kevin Landwer-Johan.

Use these fun color photography exercises to not only expand your knowledge of color but so you can use color more effectively in your photos.

The post Color Photography Exercises to Help You Improve Your Skills appeared first on Digital Photography School. It was authored by Kevin Landwer-Johan.

The post Weekly Photography Challenge – Everyday Objects appeared first on Digital Photography School. It was authored by Caz Nowaczyk.

Since many of us are still limited to where we can go, this week’s photography challenge topic is the EVERYDAY OBJECTS! Everyday objects can be anything from a cup filled with coffee, TV remote, shoes, pens, computer mouse to a guitar pick. You get the picture! Get creative with them, either with the photography style […]

The post Weekly Photography Challenge – Everyday Objects appeared first on Digital Photography School. It was authored by Caz Nowaczyk.

Led by Princeton’s Cristian Galbiati, a massive international team worked to design, test and finalize the Mechanical Ventilator Milano (MVM), a low-cost ventilator designed to ease device shortages caused by COVID-19.

Jenny Murphy believes Irish women's rugby has not developed enough in the time period since the senior team's historic Grand Slam win in 2013.

Freezing soap bubbles look like snow globes. This whimsical effect could help us improve biological freezing techniques—and is incredibly fun to watch.

Researchers are using fluid dynamics to try to improve the study of crime scene blood spatter.

A new refrigeration technique harnesses the ability of rubber and other materials to cool down when released from a tight twist.

A look at what trainers and medical experts think about NBA players returning to games.

A memo to the newsroom from Times Editor Davan Maharaj and Managing Editor Marc Duvoisin: Today we announce a reorganization involving three of our most important news departments.

Left-hander Alex Wood gave up three runs as the Dodgers lost 6-5 to the Brewers, but he believes last year's back problems are in the past.

Phyllis Lyon and her longtime partner were among the first same-sex couples to marry in California.

These sweet pillows designed by Catstudio husband-and-wife artists Terrell and Carmel Swan could be a cozy reminder of someplace special in your relationship — meeting at USC, for example, or that romantic trip to Yosemite or a honeymoon in Santa Barbara.

Jenn Shapland's "My Autobiography of Carson McCullers" and Mark Doty's "What Is the Grass," about Walt Whitman, are hybrid memoir-biographies.