Use of a standard treatment protocol with stringent weaning guidelines for infants with neonatal abstinence syndrome supports improved outcomes including shorter duration of opioid exposure and length of hospital stay.

We demonstrate generalizability of a protocol-driven weaning strategy for improvement in hospital outcomes for neonatal abstinence syndrome. After adoption, adherent protocol-adopting centers improved outcomes and eliminated differences in outcomes compared with centers with preexisting stringent weaning protocols. (Read the full article)

Interactive mobile media devices have revolutionized children’s access to and experience of media, but research is lagging behind its adoption. A critical first step is to understand when and how young children adopt mobile media devices.

Our study found almost universal exposure, early adoption, and use of mobile media devices among young children in an urban, low-income, minority community. Studies are needed to update guidelines on the use of mobile media by young children. (Read the full article)

It had been 19 years since Germany lost a qualifier but Iceland ended that run in stunning style with a 3-2 away win that finished some incredible runs by the twice world champions.

Penn State senior Abigail Cowser was recently named one of 10 American Society of Civil Engineers "2020 New Faces of Civil Engineering - College Edition."

The issue is significant not only for school employment but also for whether a related federal law would protect students on the same basis.

Pennsylvania College of Technology dental hygiene students and volunteer dental professionals will provide free dental hygiene services to veterans, members of the armed services, and their dependents on Saturday, April 4.

Educators are wrestling with tough questions as more schools embrace personalized learning and its accompanying belief in giving students more control over their academic experiences.

Very carefully, experts say, while understanding that federal laws governing special education were not written with online education in mind.

Enter PCMag.com's Readers' Choice/Business Choice Survey sweepstakes for a chance to win!

We visit the grassroots club where it all began for the EURO '96 finalist and UEFA Champions League winner.

Nationally, at least five million children have at least one parent who is undocumented. Supporting those children should be a priority if the threat of a raid is not imminent, advocates said.

All is in place for a violent confrontation in Burundi. The failed coup on 13 May has intensified opposition to President Pierre Nkurunziza’s push for a third term in office. After ten years of peace, Burundi is in danger of reopening the fault lines that once led the country into civil war.

Carbapenems are currently the preferred agents for the treatment of serious Acinetobacter infections. However, whether cefepime/cefpirome can be used to treat Acinetobacter bloodstream infection (BSI) if it is active against the causative pathogens is not clear. This study aimed to compare the efficacy of cefepime/cefpirome and carbapenem monotherapy in patients with Acinetobacter BSI. The population included 360 patients with monomicrobial Acinetobacter BSI receiving appropriate antimicrobial therapy admitted to four medical centres in Taiwan in 2012–2017. The predictors of 30-day mortality were determined by Cox regression analysis. The overall 30-day mortality rate in the appropriate antibiotic treatment group was 25.0% (90/360 patients), respectively. The crude 30-day mortality rates for cefepime/cefpirome and carbapenem therapy were 11.5% (7/61 patients) and 26.3% (21/80 patients), respectively. The patients receiving cefepime/cefpirome/carbapenem therapy were infected by Acinetobacter nosocomialis (51.8%), A. baumannii (18.4%) and A. pittii (12.1%). After adjusting for age, Sequential Organ Failure Assessment (SOFA) score, invasive procedures, and underlying diseases, cefepime/cefpirome therapy was not independently associated with a higher or lower 30-day mortality compared to the carbapenem therapy. SOFA score (hazard ratio [HR], 1.324; 95% confidence interval [CI], 1.137–1.543; P < 0.001) and neutropenia (HR, 7.060; 95% CI, 1.607–31.019; P = 0.010) were independent risk factors for 30-day mortality of patients receiving cefepime/cefpirome or carbapenem monotherapy. The incidence density of 30-day mortality for cefepime/cefpirome versus carbapenem therapy was 0.40% versus 1.04%. The therapeutic response of cefepime/cefpirome therapy was comparable to that of carbapenems among patients with Acinetobacter BSI receiving appropriate antimicrobial therapy.

Mycobacterium abscessus lung infections remain difficult to treat. Recent studies have recognized the power of new combinations of antibiotics such as bedaquiline and imipenem although in vitro data have questioned this combination. We report that the efficacy of the bedaquiline plus imipenem treatment relies essentially on the activity of bedaquiline in a C3HeB/FeJ mice model of infection with a rough variant of M. abscessus. The addition of imipenem contributed at clearing the infection in the spleen.

Dihydroartemisinin-piperaquine has shown excellent efficacy and tolerability in malaria treatment. However, concerns have been raised of potentially harmful cardiotoxic effects associated with piperaquine. The population pharmacokinetics and cardiac effects of piperaquine were evaluated in 1,000 patients, mostly children enrolled in a multicentre trial from 10 sites in Africa. A linear relationship described the QTc-prolonging effect of piperaquine, estimating a 5.90ms mean QTc-prolongation per 100ng/mL increase in piperaquine concentration. The effect of piperaquine on absolute QTc-interval estimated a mean maximum QTc-interval of 456ms (EC₅₀=209ng/mL). Simulations from the pharmacokinetic-pharmacodynamic models predicted 1.98-2.46% risk of having QTc-prolongation > 60ms in all treatment settings. Although piperaquine administration resulted in QTc-prolongation, no cardiovascular adverse events were found in these patients. Thus, the use of dihydroartemisinin-piperaquine should not be limited by this concern.

The JSE fell on Tuesday as global markets tumbled on the back of a rout in crude oil prices.

Oil prices made a spectacular comeback Thursday as fresh US-Iran tensions erupted, also helping equities advance after US labour market figures provided a glimmer of hope for the world's top economy.

BACKGROUND:

In the United States, transgender youth are at especially high risk for HIV infection. Literature regarding HIV prevention strategies for this vulnerable, often-hidden population is scant. Before effective, population-based HIV prevention strategies may be adequately developed, it is necessary to first enhance the contextual understanding of transgender youth HIV risk and experiences with HIV preventive services.

BACKGROUND:

Pediatricians are less frequently sued than other physicians. When suits are successful, however, the average payout is higher. Little is known about changes in the risk of litigation over time. We sought to characterize malpractice lawsuit trends for pediatricians over time.

True to its name, Home Chef is the homiest of meal services we've tried. The recipes are simple and not too adventurous, but for some home chefs, that's a good thing.

Credit card fraud increased to 19.47% as at the end of March 2019, compared to 12.2% reported at the beginning of January 2019.

Penn State Hazleton’s Student Services and Engagement team is continuing to forge personal connections with students while operating under the restrictions in the virtual environment created by the COVID-19 crisis.

Katie Marshall, Penn State World Campus mental health case manager, connects students learning online to resources in their own communities.

The Walkman NW-ZX2 has Bluetooth compatibility, 128GB of internal storage, and a big price tag.

You'll get a trial, but that's it. If you want any kind of free music, you'll have to stick with iTunes Radio.

Don't take your safety for granted. These apps, services, and gadgets will help you communicate your location to trusted contacts and get help should trouble arise.

Very carefully, experts say, while understanding that federal laws governing special education were not written with online education in mind.

A leading autism researcher and former special education teacher offers advice to help students cope with the abrupt changes brought on by the novel coronavirus outbreak.

Rangers vice-chairman John Bennett has criticised the SPFL for their 'cynical tactics' over their labelling of the club's dossier as a "smoking gun" - and insists the issue is not merely Gers vs the governing body.

Understanding how research is actually used by district leaders is essential for research-practice partnerships to effectively bridge research and practice in education.

If researchers hope to identify programs that will prepare students for the future, then they cannot continue to measure innovation based on the ideas from the past.

Marc Tucker looks at what the world's top performers tell us about the school choice agenda likely to be pursued by President Trump and his Education Secretary nominee Betsy DeVos.

Shoo K. Lee
Nov 1, 2000; 106:1070-1079
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Marcia E. Herman-Giddens
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England won the 2017 Maurice Burlaz Trophy, the prize awarded to the nation that achieved the best results in UEFA's men's youth competitions over the previous two seasons.

Penn State Harrisburg this spring recognized staff members who have served the college for 25 years.

If you want new printer, there's only one manufacturer to consider—the same printer maker PCMag readers have rated the very best for more than a decade.

Brother International has long dominated PCMag's Business Choice Awards for printers, but this year it's joined by another top contender.

Web hosting doesn't need to be expensive. In fact, it can be extremely low cost. If you want solid hosting that won't drain your bank account, these are the 10 best cheap web hosting services that we've reviewed.

Retail stores, corporate offices, and contact centers in China are closed through February 9 as the coronavirus spreads globally. Apple's online store will remain open, though.

Penn State Health St. Joseph opened a curbside, chest X-ray service at the medical center’s main entrance at 2500 Bernville Road on May 4. This new service is part of its continued efforts to increase patient safety during the coronavirus pandemic.

The top-rated Kindle Paperwhite, a PCMag Editors' Choice product, is available right now from $84.99 ($45 off) and the new Kindle is on sale starting at $59.99 ($30 off).

Cecelia Minnick, who will graduate this Saturday with a 3.98 GPA in accounting and minors in information systems management and legal environment of business, has been selected as Smeal’s spring 2020 accounting student marshal.

Bria Nickerson turned her love of true crime television into a passion for criminal justice. During her time at Penn State Schuylkill, this administration of justice major has distinguished herself in the classroom and as a campus leader, earning her this year's Student Life Chancellor's Award for Student Leadership for contributions to the improvement and advancement of campus life.

Penn State Schuylkill biology student Eric Thompson will graduate with honors on May 9. After surviving pediatric cancer in his early teens, Thompson has transformed a tragic situation into a passion to help people. This fall, he will embark on a new academic journey at Thomas Jefferson University’s Sidney Kimmel Medical College, where he will commit himself to earning his M.D. and delivering medical expertise to underserved communities.

This isn't the first time states and schools have turned to projects, portfolios, exhibitions, and essays to measure students' learning. Here are lessons from the last go-around.