Change is definitely on the horizon. READ MORE...

Hardcover, Kindle, Audiobook – March 3, 2020

By Carly Tennes Published: November 10th, 2024

By Carly Tennes Published: November 12th, 2024

The post 10 Ways to Take Stunning Portraits (Portrait Photography Guide) appeared first on Digital Photography School. It was authored by Darren Rowse.

How do you do portrait photography that has the wow factor? Capturing stunning portraits often seems difficult, but it’s actually pretty easy once you know a few tips and tricks. Below, I share my 10 absolute favorite techniques for shooting portraits, including tips for lighting, composition, perspective, and much more. I’ve also included plenty of […]

The post 10 Ways to Take Stunning Portraits (Portrait Photography Guide) appeared first on Digital Photography School. It was authored by Darren Rowse.

We’ve all been there – the frustration of searching high and low for that elusive piece of furniture to turn our home decorating vision into reality. For Sabrina, her search was for the ideal console table. “Unfortunately, I could not find the perfect console, so my husband had to believe in it again and build one himself!” she shared on her Instagram post. After realizing that the perfect entryway console was nowhere to be found, the couple decided to take […]

The post Failed Furniture Hunt Inspires Couple’s Fabulous Entryway Console Hack appeared first on IKEA Hackers.

In the IKEAHackers Facebook Group, Brianna shared how she turned basic KALLAX units into something totally unexpected — a gorgeous credenza that includes a perfect spot for her dog to lounge. Brianna took two 2×4 KALLAX units and set them up on either end of the nook. The middle section would be left open for a dog bed. But she didn’t stop at just placing the units – she snuck in a little hacking to give the credenza an upgraded […]

The post This IKEA KALLAX Hack Combines Storage and a Cozy Dog Bed in the Coolest Way appeared first on IKEA Hackers.

A new elevated wooden boardwalk in Fyresdal, Norway invites visitors to embrace a simultaneous expression of exceptional design and environmental sustainability. Traversing the natural landscape, the six-feet wide boardwalk gracefully snakes from the forest floor, skirting the picturesque Lake Fyresvatn. It ascends amidst the lofty treetops, culminating at the majestic summit of Klokkarhamaren, all while protecting the environment against unnecessary harm. [...]

Vampire bats rely on amino acids from their blood diet to fuel their exercise, scientists discovered after observing the animals on tiny treadmills.

Behavioral analytics, long associated with threat detection (i.e. UEBA or UBA), is experiencing a renaissance. Once primarily used to identify suspicious activity, it’s now being reimagined as a powerful post-detection technology that enhances incident response processes. By leveraging behavioral insights during alert triage and investigation, SOCs can transform their workflows to become more

The post Ukrainian Politician Has Got His Own Gilded Railway Car appeared first on English Russia.

Princeton chemists used MacMillan's µMap, a molecular mapping technology, to watch tiny changes in a DNA-protein complex called chromatin — essentially, an architecture that allows for the compaction of DNA — in the presence of genetic mutations associated with cancer.

From the moment the phonograph was discovered, things began to move upwards, so that today, for very little money, we could have music and even find out the name of the song we are currently listening to, with one click. Modern technology has changed the ways of listening to music. Music has never been more ... Read more

The post How Modern Technology has Changed the Way we Listen to Music? appeared first on Star Two.

In the early 18th century, English criminal Jonathan Wild maintained a highly organized gang of thieves and long escaped punishment by posing as an instrument of justice and helping the authorities catch other criminals independent of, or rebellious to, his control. One such criminal was Blake, who was arrested after a burglary. He was tried, convicted, and hanged. What other notorious criminal—Blake's partner in crime—escaped from prison when Blake attacked a witness at his trial?

We have already shared our thoughts on why people do blog and why blogging is still afloat despite the rise of social media. We have also reasoned the help of automated blogging and even its necessity. And after RSS Ground has updated all of its automated posters we would like to dwell in more detail […]

The post Smart Way To Set Up Automated Blog Posting appeared first on RSSground.com.

Improving organic traffic can sometimes be challenging, but if you apply the correct SEO strategies, the hard work will eventually pay off. Search engine traffic is great because it’s relevant and targeted. For most websites, organic traffic converts much better than traffic from social media or other sources. Another great advantage is that visits from […]

The post 10 Smart Ways To Increase Organic Traffic To A Website appeared first on RSSground.com.

The exoplanet candidate is about the size of Saturn and located in a Whirlpool galaxy system 28 million light-years from Earth.

Thessaloniki offers visitors 2,300-plus years of history, tremendous shopping, and a Jewish story like no other in Europe. 

The trains could be charged in a matter of minutes before setting off on their journeys

For whatever reason, every election year Broward County always manages to steal the show when it comes to shady campaign practices. The 2020 election cycle is no different, and we are not referring to the embarrassment that is the Broward Republican Executive Committee, yet but there is still plenty of time for that group of misfits to step in it.

The post Smear campaign underway against DeSantis’ sheriff pick appeared first on Shark Tank.

(Oct. 25)  Even for original and continuing Never Trumpers, there is compelling reason not to vote for Democratic presidential nominee Kamala Harris: She appears to be a clear and present […]

The post Not for Kamala Harris. No way. No how. appeared first on Quin Hillyer.

The world is wildly off track in tackling climate change, the UN says, as CO2 in the atmosphere accumulates faster than ever

A selection of photographs sent in by our readers on the theme of "railways".

Arsenal captain Martin Odegaard says he must "listen to my body" after withdrawing from Norway's squad.

Top Home Features Swaying Buyers’ Purchase Decisions

England prop Ellis Genge admits last year's World Cup semi-final defeat by South Africa is something he will carry for the rest of his career.

Marine scientist uncovers the story behind Andruha's escape from Russian military training programme.

Video shows a flooded terminal inside El Prat airport and partially submerged cars on a highway.

There were no immediate reports of casualties after heavy rain on Thursday.

Building the link to western Europe has become more urgent as the Baltics see Russia as a threat.

Southampton defender Taylor Harwood-Bellis says "there was always a pathway" after being handed his first England senior call-up by interim manager Lee Carsley - the pair worked together with England Under-21s.

1. Song Jae Rim Passes Away: South Korean Star's Last Post Goes Viral, His Cryptic Insta Bio Grabs Eyeballs  News18
2. Song Jae Rim death: South Korean actor's last Instagram post sparks concern among fans  The Economic Times
3. South Korea’s popular actor Song Jae Rim found dead in Seoul apartment  Mint
4. Song Jae Rim's recent Instagram bio update was about 'starting a long journey'  Moneycontrol
5. 'My Military Valentine' fame South Korean actor Song Jae-rim dies 39  India TV News

1. PM Modi’s Rs 12,100 crore infrastructure push to transform Bihar’s railways and roadways – Here’s all you need to know  The Financial Express
2. PM Modi to visit Bihar on Wednesday, inaugurate projects worth Rs 12,100 Cr  Deccan Herald
3. PM Modi lays foundation stone for AIIMS Darbhanga, says NDA Govt committed to welfare of people  The Hindu
4. PM Modi Bihar Visit Live: Nitish Kumar removed 'jungle raj' in Bihar, says PM Modi in Darbhanga  Moneycontrol
5. Politics News Today Live Updates on November 13, 2024: ‘BJP trying to create controversy’: Karnataka Deputy CM Shivakumar on ‘Kaalia’ remark against Kumaraswamy  Mint

velocityconf: RT @allspaw: Operations and System Safety - always a student http://t.co/1VYBEZYrK8 #devops #velocityconf

Teachers can use evidence-based strategies for delivering vocabulary instruction to improve reading comprehension and vice versa by integrating literacy across content areas. These should engage students in active processing, which is essential to student learning and retention.

Most classroom walls display rules about arriving on time or raising hands to speak. Tim Smyth’s has a sign reminding students: “You’re Not Allowed to Ask Which is Better, Marvel or DC.” Even as he sidesteps fervent debates about which comic book publisher is superior, Smyth leans into comics and graphic novels in his 10th and 11th grade social studies classes at Wissahickon High School in Ambler, Pa. He believes they can offer students an engaging entry point into history and world cultures.

Selling your services and wares online can be challenging, as today’s digital shoppers are smart and demanding. You need a customer-focused approach right from the start. The customer is the most significant pillar of modern businesses, so you need to build a genuine relationship with them if you want your online store to survive. Read […]

The 2Checkout team kicked off Feb 2019 by joining over 12,000 participants in San Jose for SaaStr Annual 2019, the largest conference in the world for B2B software. The general consensus of 2Checkout team members at the end of the conference was simple and to the point: “It. Was. Amazing.”

The Internet Archive, an online repository of web pages, was offline Thursday after its founder confirmed a major cyberattack that exposed the data of millions of users and left the site defaced.

Between vacation, end-of-year projects, the coming holidays, and other hysteria, I haven’t come up with an article this month. So here’s a quick list of things that have amazed me recently. Are we virtual yet? I’m far from the first person to find NotebookLM amazing, and I certainly won’t be the last. I did a […]

Preikestolen, Pulpit Rock, is one of Norway's most famous natural landmarks. It's located in Rogaland county, near the town of Forsand. It overlooks the stunning Lysefjorden, a narrow fjord surrounded by steep cliffs.

In this video of the 604m Rock, both the stunning beauty and dizzying height of the rock are shown. — Read the rest

The post The stunning view from Preikestolen, 604m over Norway's Lysefjorden appeared first on Boing Boing.

If killjoy leftists can wear their self-parodying and ridiculous 'Handmaid's Tale' outfits, then they can't complain when a MAGA voter plays the same game... only better.

The post MUST-WATCH: MAGA Voter Finds Hilarious Way To Sidestep Election Clothing Rules appeared first on Clash Daily.

By Cynthia Farahat On Friday 27th, 2023 at 11:00 am EST, my sweet dear younger brother Amir Farahat passed away. Amir was the most loving father I have ever seen, a great brother, son, husband, and brother-in-law. My little Miró, my little prince, my soul is shattered by your loss. I will forever mourn your […]

The human cardiovascular system has adapted to function optimally in Earth's 1G gravity, and microgravity conditions cause myocardial abnormalities, including atrophy and dysfunction. However, the underlying mechanisms linking microgravity and cardiac anomalies are incompletely understood. In this study, we investigated whether and how calpain activation promotes myocardial abnormalities under simulated microgravity conditions. Simulated microgravity was induced by tail suspension in mice with cardiomyocyte-specific deletion of Capns1, which disrupts activity and stability of calpain-1 and calpain-2, and their WT littermates. Tail suspension time-dependently reduced cardiomyocyte size, heart weight, and myocardial function in WT mice, and these changes were accompanied by calpain activation, NADPH oxidase activation, and oxidative stress in heart tissues. The effects of tail suspension were attenuated by deletion of Capns1. Notably, the protective effects of Capns1 deletion were associated with the prevention of phosphorylation of Ser-345 on p47phox and attenuation of ERK1/2 and p38 activation in hearts of tail-suspended mice. Using a rotary cell culture system, we simulated microgravity in cultured neonatal mouse cardiomyocytes and observed decreased total protein/DNA ratio and induced calpain activation, phosphorylation of Ser-345 on p47phox, and activation of ERK1/2 and p38, all of which were prevented by calpain inhibitor-III. Furthermore, inhibition of ERK1/2 or p38 attenuated phosphorylation of Ser-345 on p47phox in cardiomyocytes under simulated microgravity. This study demonstrates for the first time that calpain promotes NADPH oxidase activation and myocardial abnormalities under microgravity by facilitating p47phox phosphorylation via ERK1/2 and p38 pathways. Thus, calpain inhibition may be an effective therapeutic approach to reduce microgravity-induced myocardial abnormalities.

IQGAP1 is a key scaffold protein that regulates numerous cellular processes and signaling pathways. Analogous to many other cellular proteins, IQGAP1 undergoes post-translational modifications, including phosphorylation. Nevertheless, very little is known about the specific sites of phosphorylation or the effects on IQGAP1 function. Here, using several approaches, including MS, site-directed mutagenesis, siRNA-mediated gene silencing, and chemical inhibitors, we identified the specific tyrosine residues that are phosphorylated on IQGAP1 and evaluated the effect on function. Tyr-172, Tyr-654, Tyr-855, and Tyr-1510 were phosphorylated on IQGAP1 when phosphotyrosine phosphatase activity was inhibited in cells. IQGAP1 was phosphorylated exclusively on Tyr-1510 under conditions with enhanced MET or c-Src signaling, including in human lung cancer cell lines. This phosphorylation was significantly reduced by chemical inhibitors of MET or c-Src or by siRNA-mediated knockdown of MET. To investigate the biological sequelae of phosphorylation, we generated a nonphosphorylatable IQGAP1 construct by replacing Tyr-1510 with alanine. The ability of hepatocyte growth factor, the ligand for MET, to promote AKT activation and cell migration was significantly greater when IQGAP1-null cells were reconstituted with IQGAP1 Y1510A than when cells were reconstituted with WT IQGAP1. Collectively, our data suggest that phosphorylation of Tyr-1510 of IQGAP1 alters cell function. Because increased MET signaling is implicated in the development and progression of several types of carcinoma, IQGAP1 may be a potential therapeutic target in selected malignancies.