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Fans can attend the red carpet for The Lord of the Rings: The War of the Rohirrim World Premiere in London on Dec 3

On Tuesday December 3, London's iconic Leicester Square will host the World Premiere of the feature-length anime The Lord of the Rings: The War of the Rohirrim ahead of the general film's release on December 13 (note: some locations, such as Japan, are actually getting it a little later).

There will be a slew of cast and crew from the film in attendance: Brian Cox, Gaia Wise, and Laurence Ubong Williams, as well as director Kenji Kamiyama, producers Philippa Boyens, Jason DeMarco, and Joseph Chou, and singer Paris Paloma. Carlos Laloli, Peter Jackson, Ken Kamis, Sam Register, Phoebe Gittins and Arty Papageorgiou will also be there.

Warner Bros. says it will be setting setting up a an area for a "limited number of fans to watch the red carpet arrivals". Warner Bros. also say they are setting up a ballot, and are taking applications for double passes.

Applications will close at 23:59 GMT Wednesday 20th November and winners will be drawn at random.

  • Click here to apply for access to the GENERAL ACCESS FAN AREA
  • Click here to apply for access to the ACCESSIBLE FAN AREA

In addition, there will be a live stream of the red carpet with details to be announced soon. Stay tuned, I guess!

Source: Warner Bros.






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Baby milk prices 'punish those who don't breastfeed'

Parents say they feel penalised by the high cost of formula, which cannot be discounted under the law.




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Don't Lose Sleep Over the End of Daylight Saving: Tips for a Smooth Adjustment

Highlights: Maintaining your usual sleep schedule, even during daylight saving shifts, helps keep your circadia





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Bad Hires Can Cost You Thousands to Replace — and AI May Be to Blame. Try These 3 Ways to Ensure You Don't Fall Into Its Trap.

Over-relying on AI-driven hiring tools means taking human intuition out of the hiring process. The result? You miss out on top talent and risk stifling long-term growth.




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Donald Trump Hires Elon Musk and Vivek Ramaswamy to Bring 'Drastic Change' to the U.S. Government — And Gives Them a 2 Year Deadline

Musk and Ramaswamy have to find ways to cut down on government spending and overall bureaucracy.




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Don Lemon officially leaves Elon Musk’s X

Former CNN anchor Don Lemon said on Wednesday he is leaving Elon Musk’s X, a decision made less than a year after X announced that “The Don Lemon Show” would appear on the social media platform three times a week. That deal was canceled before it was ever signed, and Lemon sued Musk and X […]

© 2024 TechCrunch. All rights reserved. For personal use only.




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Meet Vivek Ramaswamy, Harvard-Yale graduate, son of immigrants, now part of Donald Trump's cabinet, his net worth is...

Born in the US to Indian immigrant parents, Ramaswamy gained wealth through his biotech company




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Asymmetric [3 + 2] cycloaddition of donor–acceptor cyclopropanes with azadienes enabled by Brønsted base catalysis

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00002A, Research Article
Shu Li, Zhi-Hong Dong, Si-Yu Dan, Mei-Jun Zheng, Teng Long, Jie Zhan, Qing Zhou, Wen-Dao Chu, Quan-Zhong Liu
A chiral bifunctional Brønsted base-catalyzed enantioselective [3 + 2] cycloaddition of D–A cyclopropanes and azadienes is reported. The protocol features broad substrate scope, mild reaction conditions and high functional group tolerance.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Electron donor–acceptor complex photoactivation for deaminative alkynylation, alkenylation and allenylation: a comprehensive study

Org. Chem. Front., 2024, 11,2231-2240
DOI: 10.1039/D4QO00177J, Research Article
Romain Lapierre, Lina Truong, Matthieu Hedouin, Hassan Oulyadi, Bruno Schiavi, Alexandre Jean, Philippe Jubault, Thomas Poisson
Herein, we disclose our study toward photoinduced deaminative alkynylation, alkenylation and allenylation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Palladium-catalyzed asymmetric [4 + 3] cycloaddition of acyclic α,β-unsaturated imines with trimethylenemethane donors: access to chiral non-fused azepines

Org. Chem. Front., 2024, 11,2326-2331
DOI: 10.1039/D4QO00064A, Research Article
Ting-Peng Li, Shuixiu Su, Jia-Huan Shen, Meng Zang, Yang-Zi Liu, Quannan Wang, Wei-Ping Deng
An efficient approach for the construction of non-fused azepines in good yields with high enantioselectivity via Pd-catalyzed asymmetric [4 + 3] cycloaddition was developed.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Thiourea as a precatalyst for the electron donor–acceptor complex photoactivation platform of oxime esters

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00424H, Research Article
Haichen Mao, Yuting Zhang, Hengrong Cao, Qianqian Shi, Yu Lan, Junbiao Chang, Bo Zhu
A novel electron donor–acceptor (EDA) complex catalysis strategy has been developed using thiourea as a precatalyst under blue LED irradiation. Using 2–5 mol% of thiourea, various nitrogen-containing compounds were successfully synthesized.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Indonesia and Australia hold joint military drills after signing a new defense agreement

The Indonesian and Australian militaries are holding joint combat drills off Indonesia’s main island of Java with about 2,000 troops training in air, maritime, amphibious and land operations




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In vitro identification of oridonin hybrids as potential anti-TNBC agents inducing cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP

RSC Med. Chem., 2024, 15,3674-3694
DOI: 10.1039/D4MD00580E, Research Article
Jinhua Ning, Nini Zhan, Zhanpan Wu, Yuzhe Li, Die Zhang, Yadian Shi, Yingxun Zhou, Chuan-Huizi Chen, Wenbin Jin
Oridonin analogue 11a showed significant antitumor efficacy in vitro via cell cycle arrest and apoptosis by regulation of p21, γH2AX and cleaved PARP accumulation, meanwhile, displayed much more stable than oridonin in human plasma.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Furoxan–piplartine hybrids as effective NO donors and ROS inducers in PC3 cancer cells: design, synthesis, and biological evaluation

RSC Med. Chem., 2024, 15,3778-3794
DOI: 10.1039/D4MD00281D, Research Article
Carolyne Brustolin Braga, Julio Cesar Milan, Matheus Andrade Meirelles, Bruno Zavan, Guilherme Álvaro Ferreira-Silva, Ester Siqueira Caixeta, Marisa Ionta, Ronaldo A. Pilli
A novel hybrid integrating piplartine with a furoxan moiety exhibited a sub-micromolar IC50 and extraordinary selectivity for PC3 cells, which was associated with its capacity to release NO, generate ROS, induce DNA damage, and trigger apoptosis.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Donald Trump meets Joe Biden in White House; both pledge smooth transition

In a brief meeting, the two leaders assured the nation of a peaceful transition of power on January 20, 2025.




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Don’t follow self-healing methods to control diabetes, says diabetologists




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Indonesia's volcanic eruption grounds international flights on tourist island of Bali

Indonesia's Mount Lewotobi Laki Laki volcano on the remote island of Flores in East Nusa Tenggara province spewed towering columns of hot ash high into the air since its initial huge eruption on November 4 killed nine people and injured dozens of others




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Meet Tulsi Gabbard, Hindu American who is appointed by Donald Trump as US director of national intelligence

Gabbard, who has served in the Army National Guard for more than two decades, deploying to Iraq and Kuwait, would come to the role as somewhat of an outsider, compared to her predecessor.




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'Citadel Makers Could Have Done More...'

'On the big screen, we focus on hope for your dreams whereas OTT is the bitter reality.'




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Chrome Update to Kill Many Addons, including Blockers

Almost one in six Chrome extensions could stop working this summer thanks to a major Google update. They include one of the most prominent ad-blocking tools. An extension is a third party tool that integrates with Chrome to improve the user's experience when accessing websites. They can include tools as diverse as password managers, page translators and video downloaders, though ad blockers are perhaps the best known. Extensions are able to integrate with Chrome and access its data thanks for a platform called Manifest. Google has developed a Version 3 of Manifest and is phasing out support ... (view more)




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Why Do Some Parishes Reach Out and Others Don't?

Assembly of Bishops Researcher Alexei Krindatch joins Fr. Barnabas to discuss the latest study on evangelism in the Orthodox Church.




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Donald Trump selects Tulsi Gabbard to oversee intelligence gathering

President-elect Donald Trump said he plans to nominate former Rep. Tulsi Gabbard as the director of national intelligence, the Cabinet member in charge of gathering and sharing sensitive foreign information and secrets.




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E. coli cases tied to McDonald's Quarter Pounders climb to 104

At least 104 people have been sickened, with 34 hospitalized, in an outbreak of E. coli food poisoning tied to onions served on McDonald's Quarter Pounder hamburgers, federal health officials said Wednesday.




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Donald Trump triumphantly returns to White House as Joe Biden pledges 'smooth transition'

President-elect Donald Trump made his victorious return to Washington on Wednesday, meeting with jubilant House Republicans and then conferring with President Biden in the Oval Office, where they mutually pledged a smooth transfer of power after a bitter election in which they repeatedly disparaged each other.




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Analyzing spatial patterns of thermal alteration in the Stikine and Wrangell terranes of the Canadian Cordillera using the conodont color alteration index (CAI) to identify hot spots and cold spots

Lei, J Z X; Golding, M L; Husson, J M. Geological Survey of Canada, Open File 8746, 2020, 43 pages, https://doi.org/10.4095/327243
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_327243.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_327243.jpg" title="Geological Survey of Canada, Open File 8746, 2020, 43 pages, https://doi.org/10.4095/327243" height="150" border="1" /></a>




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Middle-Upper Devonian conodont faunas and biostratigraphy of the Horn River Group in the northern Mackenzie Mountains and Plain (NWT, Canada)

Gouwy, S A. Geoconvention 2020, abstract archive; 2020 p. 1
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20200407.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20200407.jpg" title="Geoconvention 2020, abstract archive; 2020 p. 1" height="150" border="1" /></a>




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Erratum for 'Devonian (c. 388-375 Ma) Horn River Group of Mackenzie Platform (NW Canada) is an open-shelf succession recording oceanic anoxic events', Journal of the Geological Society, London, 176, 29-45

Kabanov, P. Journal of the Geological Society vol. 177, 2020 p. 231, https://doi.org/10.1144/jgs2019-205
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20190636.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20190636.jpg" title="Journal of the Geological Society vol. 177, 2020 p. 231, https://doi.org/10.1144/jgs2019-205" height="150" border="1" /></a>




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Evaluation and optimization of acid processing procedures for the extraction of conodont elements from calcareous rock

Gallotta, C; Gouwy, S A; Komaromi, L. Geological Survey of Canada, Open File 8792, 2021, 50 pages, https://doi.org/10.4095/328273
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_328273.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_328273.jpg" title="Geological Survey of Canada, Open File 8792, 2021, 50 pages, https://doi.org/10.4095/328273" height="150" border="1" /></a>




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Devonian conodont biostratigraphy of the Mackenzie Mountains, western part of the Northwest Territories

Re-release; Gouwy, S A. Sedimentary basins of northern Canada: contributions to a 1000 Ma geological journey and insight on resource potential; by Lavoie, D (ed.); Dewing, K (ed.); Geological Survey of Canada, Bulletin 609, 2022 p. 159-184, https://doi.org/10.4095/326098
<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326098.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_326098.jpg" title="Sedimentary basins of northern Canada: contributions to a 1000 Ma geological journey and insight on resource potential; by Lavoie, D (ed.); Dewing, K (ed.); Geological Survey of Canada, Bulletin 609, 2022 p. 159-184, https://doi.org/10.4095/326098" height="150" border="1" /></a>




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Focus on London

Post&Parcel Live is a seminar series from the experts at Post&Parcel (www.postandparcel.info). On 27 April 2017 we launched our first seminar titled "Solving the Inner City Challenge". In this keynote Tim Ward, Freight and Fleet Programme Manager at Transport for London gives a focus on London.



  • Inner City Challenge

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Scurri: HelloDone’s technology offering is highly complementary to ours

Delivery management platform, Scurri, today announced the acquisition of HelloDone, the UK-based, market-leading artificial intelligence (AI) platform which provides conversational AI solutions to retailers and brands. 







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Fox Hosts ‘Don’t Remember Republicans Acting Out’ After Biden Won

It’s no surprise that the sore winners at Fox News are already working to demonize people that don’t love the Felonious p***y grabber as much as they do. But in this case, they really ought to come up with better material.

Media Matters caught the delusional exchange on Fox & Friends this morning. It started out with cohost Steve Doocy saying “people are all entitled to their opinion” but since Trump just won a four-year term, “just deal with it.”

read more




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Fox News Lawyer Suggests Trump Commit Extortion For Pardon

Fox News legal editor Kerri Urbahn told 'The Story with Martha McCallum that Trump could force a pardon from Gov. Hochul by threatening to withhold federal funds to New York unless she pardons his 34 felonies.

This shouldn't come as a surprise since Urbahn was the Director of Public Affairs for the Department of Justice under Attorney General Bill Barr during the first Trump administration.

This segment was prompted by the judge delaying a decision on Trump's 34 felony convictions for another week.

MACCALLUM: Governor Hochul could also pardon President Trump on these charges because it is a state charge, right?

URBAHN: Yeah that's right and look she needs to really be thinking through this because New York state needs federal money and they get a lot of it.

And there is a lot that the federal government could do in terms of pulling funding from both the city and the state of New York. There's a bunch of ways to do it through the Justice Department and other places, and you know, at the end of the day it's all politics.

read more




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I DON'T KNOW DENISE

I DON'T KNOW DENISE sometimes I feel like we live in a slum




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The Internet Watches as the Mystery of the London Bridge Wedding Photo Unfolds

This photo was taken by passing photographer, Saber Miresmailli, who then took to the internet to find the lovely couple.  Responses have been tremendous and a Twitter user came forward claiming to know the couple.  The photographer then made a statement on his Facebook page saying that, until they come home from their honeymoon and claim the picture, their identities are unconfirmed. 

Finally, they have returned from their honeymoon and even did an interview with ITV News London.  They say they were shocked at the attention they got and basically agree that it's a very nice picture. 




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See What Happens When They Don't Listen To The Lady?

October is Breast Cancer Awareness Month. I TOLD those scientists they should be finding a cure for breast cancer instead of playing around with that atomic energy nonsense, but NO....




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Why the name switch from Snowdonia to Eryri matters

For many Welsh speakers, Eryri and Yr Wyddfa are the names they have used all along.




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London, Rome, Paris Top TripAdvisor's Most-Reviewed Cities List

Filed under: , , , ,

Alamy
The litany of year-end travel-related lists continues. Today, it's TripAdvisor, which unveiled its most reviewed cities. Leading the way: London, Rome and Paris, according to the Telegraph. The top U.S city was New York, which ranked fourth overall -- a stunning blow for American exceptionalism.

Continue reading London, Rome, Paris Top TripAdvisor's Most-Reviewed Cities List

London, Rome, Paris Top TripAdvisor's Most-Reviewed Cities List originally appeared on Gadling on Tue, 17 Dec 2013 14:11:00 EST. Please see our terms for use of feeds.

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Donald Trump’s policies risk making the US dollar a source of global instability

Donald Trump’s policies risk making the US dollar a source of global instability Expert comment LToremark

Although Trump favours a weaker exchange rate, his policies are likely to have the opposite effect. The risk is that the US dollar could become too strong, which is bad news for the global economy.

President-elect Donald Trump has a dollar problem. In recent months he has shown a clear preference for a weaker exchange rate to support the competitiveness of US exports and help reduce the US trade deficit. And yet, as the market has sensed since the US election, the much more likely outcome is that his policies end up strengthening the greenback. The risk is that the US dollar – which is expensive already – becomes more obviously overvalued, and this could increase the risk of global financial instability. 

The risk is that the US dollar – which is expensive already – becomes more obviously overvalued, and this could increase the risk of global financial instability. 

The dollar has been on a rollercoaster ride in the past few decades. From 2002 until 2011, for example, the dollar weakened by around 30 per cent in inflation-adjusted, trade-weighted terms, according to BIS data. Yet in the years since 2011, the dollar has strengthened and is now at a more appreciated level than at any time since 1985.

What shapes this rollercoaster, broadly speaking, is the global balance of economic vitality: when the US economy gains momentum relative to the rest of the world, the dollar tends to strengthen; and vice versa. 

After China joined the WTO in 2001, the balance of economic vitality shifted decisively away from the US, in favour of China and other emerging economies. This was the decade of the commodity boom: the longest, biggest peacetime increase in commodity prices in nearly 200 years during which a sustained surge in China’s economy supported GDP growth across the developing world. The dollar weakened as a result.

But after 2011, a combination of factors – including the eurozone crisis and its aftermath, together with the sagging of the Chinese economy – tipped the balance of economic vitality back in favour of the US. The dollar strengthened once again.

And since both the European and Chinese economies remain very fragile, the balance of economic vitality seems likely to keep favouring the US dollar.

Two more considerations also point to a stronger US dollar under a second Trump administration.

The first is the exchange rate implications of Donald Trump’s proposed tariffs on imports. When the US imposes tariffs on a trading partner, the foreign exchange market tends to sell that trading partner’s currency, forcing it to weaken to offset the dollar-price increase induced by the tariff. This helps explain why the Chinese renminbi depreciated by some 10 per cent in 2018 after Trump began imposing trade restrictions on China in January of that year. 

More widespread tariffs on a whole range of US trading partners should therefore strengthen the dollar more broadly.

A stronger dollar should also result from the macroeconomic framework Trump seems likely to deliver. He will certainly want to extend his 2017 tax cuts beyond 2025 when they are currently due to expire, so a more sustained loosening of US fiscal policy seems likely. Since boosting the US economy will create inflationary pressure, the market will expect interest rates to end up higher than they might otherwise be. The resulting combination of looser fiscal and tighter monetary policy tends to be a stronger currency.

The dollar probably has a fair amount of room to keep going up, since it is not obviously overvalued just yet. The US current account deficit – the broadest measure of a country’s trade deficit, and a rough but useful measure of financial vulnerability – was a little over 3 per cent of GDP last year. 

This is around half the level it reached in 2006, just before the 2008 global financial crisis, meaning the risks arising from an overvalued dollar may be for the latter part of Trump’s second presidency.

A strengthening dollar is also not great news for the rest of the world economy. A strong dollar tends to depress global trade growth, restrict developing countries’ access to international capital markets, and make it more difficult for countries whose currencies will be weakening to keep inflation under control.

If and when the dollar becomes unsustainably expensive, a further problem will present itself: how to deal with an overvalued currency without risking a lot of financial dislocation.

This problem last occurred in early 1985, when the dollar was universally reckoned to be dangerously dear. At that time the US was able to call on trading partners who depended on the US security umbrella – the UK, Germany, France and Japan – to negotiate the ‘Plaza Accord’, which coordinated a series of interventions in the foreign exchange market that allowed the dollar to decline in a measured way.  

Without much scope for a negotiated decline in the dollar, more chaotic alternatives seem likely. 

It is virtually unimaginable that something similar could be negotiated today, not least because Chinese policymakers believe that the post-Plaza strengthening of the yen in the late 1980s led to an economic disaster for Japan. Beijing will not play ball.

Without much scope for a negotiated decline in the dollar, more chaotic alternatives seem likely. 

One is that the market decides suddenly that it no longer has an appetite for expensive dollar-denominated assets, and this might lead to a messy adjustment in the foreign exchange market. 




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Disinformation enabled Donald Trump&#x2019;s second term and is a crisis for democracies everywhere

Donald Trump did not win the 2020 election, but asserting that he did became a prerequisite for Republicans standing for nomination to Congress or the Senate to win their primaries. An entire party became a vehicle for disinformation.1 Trump did win the 2024 presidential election, and key to that victory was building on the success of that lie. If you control enough of the information ecosystem, truth no longer matters.Another telling example: Haitian migrants in Springfield, Ohio, are not eating cats and dogs. US vice president elect, JD Vance, the source of that claim, admitted as much even as he justified it. “If I have to create stories so that the American media actually pays attention to the suffering of the American people, then that’s what I'm going to do,” he said.2Disinformation in politics is nothing new. History is replete with claims that were fabricated to advance political aims. Although...




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Malcolm Donaldson: paediatric endocrinologist, musician, and proud collaborator with his wife Julia, author of The Gruffalo

bmj;387/nov12_10/q2481/FAF1faJulia and Malcolm Donaldsondonaldson20241111.f1Malcolm Donaldson was a distinguished paediatric endocrinologist with a string of research publications to his name—but he was also happy to play second fiddle (almost literally) to his wife Julia, the celebrated author of much loved children’s books, including The Gruffalo and Room on the Broom.Malcolm, a talented musician and performer, accompanied his wife as she toured festivals, schools, and libraries in the UK and around the world. Together they performed the stories, with Malcolm acting characters ranging from an accident prone dragon to a comic cattle thief. His star role, in the words of Julia’s literary agent, was “a particularly suave fox” in The Gruffalo.Malcolm met Julia Shields when they were students at the University of Bristol and they married in 1972. Donaldson went on to work in Brighton, London, and Lyon, France, before moving back to Bristol to be a senior registrar in paediatrics. Six...




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Abandoning ruinous traditions

A woman from a least-reached group of people accepted Christ during Discipleship Centre student outreach.




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Playing and sharing in London

Mikael from Norway is 18 years old and passionate for Jesus. Recently he shared his faith during a sports outreach in London.




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Don't worry, trust Jesus

In partnership with a local church, OM Lifehope teaches truths about God and the Bible to children at their recent Easter holiday club.