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Amides of moronic acid and morolic acid with the tripeptides MAG and GAM targeting antimicrobial, antiviral and cytotoxic effects

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00742E, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Uladzimir Bildziukevich, Lucie Cerna, Jana Trylčová, Marie Kvasnicova, Lucie Rárová, David Šaman, Petra Lovecká, Jan Weber, Zdenek Wimmer
A series of amides of the selected plant triterpenoids, moronic acid and morolic acid, with the tripeptides MAG and GAM was designed and synthesized. Two required tripeptides 5 and 10...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Metal-free synthesis of N-fused quinazolino-quinazoline-diones as a MALAT1 RNA triple helix intercalator

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00614C, Research Article
Vijay Babu Pathi, Pranotosh Das, Abhyuday Guin, Manish Debnath, Biswadip Banerji
The development of chemical scaffolds that target highly conserved MALAT1 RNA received attention due to its significance in splicing, nuclear organization, and gene expression in disease progression pathways.
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553: TypeScript, DX, GripeScript, and Astro v2 with Fred Schott

Fred Schott stops by to talk about TypeScript, what DX means in 2023, a bit of GripeScript, and being transparent about what Astro is good at, and what it's not.




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572: Text Sqwunch Property, Figma Developer Mode, Stripe Elements

Show DescriptionDave reports back from the Figma Conference, how to build a better developer to designer bridge, do clients really want to update their website, using Stripe in 2023, permissions and sharing, and are you feeling overwhelmed by CSS in 2023? Listen on Website →Links Config 2023 | Figma’s Annual Conference Figma Visual Studio Code […]




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593: Beep & Texts, Tumblr, JavaScript & Web Components, & Cool Blog Post Ideas

Thoughts on smashing all communication messaging apps together, what's happened to Tumblr under Automattic, what the situation is with native web components and JavaScript, and looking at a list of types of blog posts.




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603: Deno, React Alternatives, and Copilot Concerns with Triple Threat Josh Collinsworth

Josh (or Jsoh) stops by to talk about his work at Deno, recent blog posts on Copilot, why Svelte is awesome and React is not, Apple and PWA, and building word games on the web.




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610: TypeScript in 2024, Signals, Productivity Sniped, and Follow Up

Dave's about to be eclipsed, the state of TypeScript in 2024, signals stage zero proposal, corrections on accessibility in frameworks (thanks!), web apps for better collaborative writing, getting productivity sniped, the problem with email may be you, indieweb follow up, and ultimate guitar tab apps.




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611: React! TypeScript! Jobification! Drupal!

Dave & Chris and thoughts on career advice that worked 3 years ago but isn't as helpful now, marking tests with ChatGPT, is taking a Drupal job in 2024 a good idea, Chris got #gear sniped, P3 color follow up, the confusing File System APIs, and where did all the lightboxes go?




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Coming to grips with mega disasters

Rooted in research, the book reveals the existential threats we face and charts the roadmap ahead




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Policy prescription for economic and political maladies

Bimal Jalan delves deep into issues that are critical to the country with suggestions on how to overcome challenges 




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Filmmaker-farmer duo script a story of transformation with natural farming

Vishy, a Rex Karmaveer Chakra Fellowship awardee advocates popularising the farming practices and the broader promotion of natural farming and popularising his co-award winner Narayanappa’s farming practices




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Mango growers demand uniform relief of ₹30,000 per acre, fixed prices at tripartite meeting in Krishnagiri




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After loss of one vision, carpenter overcomes odds to script a success story in farming

After Udayakumar, from Mahadevikadu, near Haripad, lost his vision in one eye 15 years ago, his career as a woodworker came to an abrupt end. He then turned to agriculture to find solace and success through determination and resilience.




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By 2021, India to have 810 m smartphone subscriptions




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Network interactions simultaneously enhance stiffness and lubricity of triple-network hydrogels

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00969J, Paper
Nabila Ali, Connor J. Demott, Olivia F. Dingus, Melissa A. Grunlan, Alison C. Dunn
Tough hydrogels with a charge-variable third network were assessed for biomimicking lubricity in both water and FBS solution.
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Ripple Button Effect Using Pure CSS

Google’s Material Design guidelines introduced the ripple effect, a subtle animation that indicates user action. The ripple effect rapidly gained popularity in web design as a sophisticated visual feedback form that refines user interaction, particularly on buttons. Today, we’ll show …




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Creating ripples in a pool

Jenifir K. Sharma, the latest to join the fitness bandwagon, is going all out to promote aqua zumba in Bengaluru




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Shriram Properties to quadruple profit, triple revenue by FY27

“Shriram Properties will embrace the new era under the banner SPLNxT to reposition the brand; enhance focus on mid-market and mid-premium segments, and accelerate growth”




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Ind vs NZ 3rd Test: New Zealand scripts history as India suffers Test series whitewash

No team had been able to win all the Test matches in India in a series featuring three or more Test matches in nine decades.




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Retraction: Highly sensitive cadmium sulphide quantum dots as a fluorescent probe for estimation of doripenem in real human plasma: application to pharmacokinetic study

RSC Adv., 2024, 14,35992-35992
DOI: 10.1039/D4RA90134G, Retraction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Marwa F. B. Ali, Baher I. Salman, Samiha A. Hussein, Mostafa A. Marzouq
The content of this RSS Feed (c) The Royal Society of Chemistry




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Poorva wins triple jump gold with meet record; men’s pole vault final postponed as pit reaches late




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PIX: New Zealand script historic win in Bengaluru

IMAGES from Day 5 of the first Test played between India and New Zealand, in Bengaluru, on Sunday.




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Joe Biden set to announce new student loan relief ahead of upcoming trip

Biden is also expected to reveal federal actions as part of his administration’s efforts to replace the nation’s lead pipes within a decade




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Generating Random Mazes with JavaScript

I didn't get a chance to hit the pumpkin patch this year, so I missed out on seeing any corn mazes. To make up for it, I decided to make some mazes of my own! Being a programmer, I over-engineered it and built a random maze generator!




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Investors flock to Sovereign Gold Bonds despite price rises, FY24 sees record subscriptions

SGBs offer a hedge against gold price fluctuations, with investors receiving the ongoing market price at redemption



  • Gold & Silver

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Gold rush grips Asia despite near-record prices

Gold demand has also been boosted due to lower confidence in other investment options, such as real estate and equities, analysts say



  • Gold & Silver

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Influence of triphosphine ligand coordination geometry in Mn(I) hydride complexes [(P∩P∩P)(CO)2MnH] on their kinetic hydricity

Dalton Trans., 2024, Accepted Manuscript
DOI: 10.1039/D4DT02496F, Paper
Sergey A. Kovalenko, Ekaterina S. Gulyaeva, Elena S. Osipova, Oleg A. Filippov, Anastasia Danshina, Laure Vendier, Nikolay V. Kireev, Ivan A. Godovikov, Yves CANAC, Dmitry A. Valyaev, Natalia Belkova, Elena Shubina
Octahedral Mn(I) complexes bearing tridentate donor ligands [(L∩L’∩L’’)(CO)2MnX] have recently emerged as major players in catalytic (de)hydrogenation processes. While most of these systems are still based on structurally rigid pincer...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Triple-shelled Ni@MnO/C hollow spheres with enhanced performance for rechargeable zinc-ion capacitors

Dalton Trans., 2024, Advance Article
DOI: 10.1039/D4DT02303J, Paper
Tao Xiang, Zaiting Qu, Daohong Zhang, Chenglong Hu, Zhen Chen, Qiufan Wang
Ni/MnO@C nanospheres with different core–shell structures are obtained by using Ni3Mn-MOFs as templates, exhibiting excellent electrochemical properties as cathodes in zinc-ion storage.
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Tunability of triplet excited states and photophysical behaviour of bis-cyclometalated iridium(III) complexes with imidazo[4,5-f][1,10]phenanthroline

Dalton Trans., 2024, 53,17934-17947
DOI: 10.1039/D4DT01996B, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Katarzyna Choroba, Joanna Palion-Gazda, Mateusz Penkala, Patrycja Rawicka, Barbara Machura
The impact of cyclometalating ligands on the photophysical behaviour of heteroleptic Ir(III) complexes with imidazo[4,5-f][1,10]phenanthroline. [Ir(ppy)2(imphen)]+ is a 3MLLCT emitter, while [Ir(pybzth)2(imphen)]+ has a predominant 3LCN∩C character.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Beyond the triple bond: unlocking dinitrogen activation with tailored superbase phosphines

Dalton Trans., 2024, Advance Article
DOI: 10.1039/D4DT02703E, Paper
Vilakkathala U. Krishnapriya, Cherumuttathu H. Suresh
Dinitrogen activation has long been a challenging goal in chemistry. Tailored superbase phosphines offer a promising approach to overcome this challenge by going beyond the traditional triple bond.
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Modular synthesis of triphenylphosphine-derived cage ligands for rhodium-catalyzed hydroformylation applications

Dalton Trans., 2024, Advance Article
DOI: 10.1039/D4DT02627F, Paper
Wenlong Wang, Cunyao Li, Wenhao Wang, Yuqin Qiu, Hongguang Liu, Jinlong Lu, Yizhou Zhan, Li Yan, Yunjie Ding
Cage ligands can be easily synthesized via dynamic imine chemistry, and a specific cage ligand exhibits excellent performance in Rh-catalyzed hydroformylation reaction (TOF up to 2665 h−1 and the l/b ratio reaches 2.6).
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Asymmetric triply bridged lanthanide binuclear clusters with distinctly different magnetic behaviors

Dalton Trans., 2024, Accepted Manuscript
DOI: 10.1039/D4DT02652G, Communication
Yue Yang, Yu-Xia Wang, Yu-Zhe Lei, Peng Cheng
Isomorphic binuclear clusters Gd and Dy with antiferromagnetic and ferromagnetic couplings are separately exhibiting single-molecule magnetic behavior and strong magnetocaloric entropy.
The content of this RSS Feed (c) The Royal Society of Chemistry




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A trip to Panchmarhi

A college tour to the picturesque destination breaks the ice




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Maharashtra key to India's growth story being scripted in Modi 3.0: EAM Jaishankar




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UV-LED irradiation for biofouling reduction in drip irrigation emitters fed with wastewater effluent

Environ. Sci.: Water Res. Technol., 2024, 10,2723-2735
DOI: 10.1039/D4EW00271G, Paper
Open Access
Yael Gilboa, Barak White, Inbar Shlomo, Karl G. Linden, Eran Friedler
To improve efficiency of drip irrigation emitters fed by treated wastewater, it is desired to minimize biofouling clogging. In the present study efficiency of UV-LED and chlorine to reduce biofilm formation was compared.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Applicability of β-lactamase entrapped agarose discs for removal of doripenem antibiotic: reusability and scale-up studies

Environ. Sci.: Water Res. Technol., 2024, Advance Article
DOI: 10.1039/D4EW00572D, Paper
Huma Fatima, Amrik Bhattacharya, Sunil Kumar Khare
Schematic diagram illustrating antibiotic removal via β-lactamase-entrapped agarose discs in a fixed-bed column bioreactor, highlighting the potential for scale-up.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Solar cell manufacturing to outstrip global demand by 2024: report

The sector experienced huge growth in 2023 with solar cell, wafers and modules capacity nearly doubling in comparison with the previous year, says World Solar Market Report 2024




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Man stripped and thrashed in Thenmala




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COVID-19 triples across Europe on past six weeks; hospitalisations double: World Health Organisation

WHO's Europe director Dr. Hans Kluge described COVID-19 as “a nasty and potentially deadly illness” that people should not underestimate.




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‘The violence, to me, seemed scripted against Dalits,’ says Ajaz Ashraf, author of Bhima Koregaon — Challenging Caste

Different castes remember the incident at Bhima Koregaon on January 1, 2018, and the reasons for it differently




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Stress regulation via surface micro-etching and reconstruction for enhancing triple-cation perovskite solar cells with an efficiency of 25.54%

Energy Environ. Sci., 2024, Advance Article
DOI: 10.1039/D4EE04248D, Paper
Yang Ding, Erming Feng, Siyuan Lu, Jianhui Chang, Caoyu Long, Sichao Tong, Hengyue Li, Junliang Yang
A surface micro-etching and reconstruction strategy is developed to regulate the stresses in a perovskite film, achieving a benign transition from tensile stress to compressive stress.
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Reinforcing the symmetry of stripping/plating behavior via in situ interface construction for long-lasting zinc metal batteries

Energy Environ. Sci., 2024, 17,8855-8865
DOI: 10.1039/D4EE03102D, Paper
Dongmin Li, Yunpeng Zhong, Xieyu Xu, Daren Zhou, Yan Tang, Liangbing Wang, Shuquan Liang, Bingan Lu, Yangyang Liu, Jiang Zhou
Asymmetry of stripping/plating of the Zn anode dominates dendrite evolution and cell failure. To regulate it, a 2H8D electrolyte with a water-poor solvated structure is designed to construct a Cl-rich SEI, achieving long-lasting reversibility of ZBs.
The content of this RSS Feed (c) The Royal Society of Chemistry




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The prescription is no more AIIMS or CHCs

Rural Community Health Centres and the new AIIMS have a high staff vacancy; the solution is to manage things efficiently with the resources that are available




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Industrial AI firm Avathon to focus on India for R&D growth, aims to triple workforce in two years

India will play a pivotal role in our expansion, serving as a hub for product engineering, delivery, support and R&D, says CEO Johan




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Integrated transcriptomics and untargeted metabolomics reveal bone development and metabolism of newly weaned mice in response to dietary calcium and boron levels

Food Funct., 2024, 15,10853-10869
DOI: 10.1039/D4FO03657C, Paper
Shuo Li, Xuehai Cao, Tiande Zou, Zirui Wang, Xingping Chen, Jun Chen, Jinming You
Boron supplementation in diets with varying calcium levels modulates bone development and bone parameters in mice by regulating calcium signaling, lipid metabolism, and neural signaling and inflammatory signaling.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Metagenomic and transcriptomic profiling of the hypoglycemic and hypotriglyceridemic actions of Tremella fuciformis-derived polysaccharides in high-fat-diet- and streptozotocin-treated mice

Food Funct., 2024, 15,11096-11114
DOI: 10.1039/D4FO01870B, Paper
Xiaofei Xu, Xiaofei Liu, Liyan Liu, Jin Chen, Jingjing Guan, Donghui Luo
Tremella fuciformis polysaccharides exhibit hypoglycemic and hypotriglyceridemic activities through altering the taxonomic and functional attributes of the gut microbiota and modulating gene expression in the liver.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Correction: Using integrated transcriptomics and metabolomics to explore the effects of infant formula on the growth and development of small intestinal organoids

Food Funct., 2024, Advance Article
DOI: 10.1039/D4FO90094D, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Xianli Wang, Yuxin Jing, Chengdong Zheng, Chenxuan Huang, Haiyang Yao, Zimo Guo, Yilun Wu, Zening Wang, Zhengyang Wu, Ruihong Ge, Wei Cheng, Yuanyuan Yan, Shilong Jiang, Jianguo Sun, Jingquan Li, Qinggang Xie, Xiaoguang Li, Hui Wang
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Ripley Review

The show takes its own pace to pick up, but then when you least expect, it grabs you by the throat, notes Aseem Chhabra.




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Add Class To Body If JavaScript Is Enabled

This snippet is super small but is super handy. It detects to see if JavaScript is enabled on the users browser. If yes, a class will be added to the <body> tag Adds the class yourClassName to <body> tag if Javascript is enabled.

The post Add Class To Body If JavaScript Is Enabled appeared first on Web Design Weekly.




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Gripping mythological

The play ‘Bhakta Markandeya’ by Savera Arts, Kadapa was gripping and entertaining.