A fully Keynesian approach will need to be taken by the government. People are losing jobs and production activity has come to a standstill due to the lockdown.

•Dassault Systèmes collaborated with SATS, Asia’s leading food solutions and gateway services provider, to boost operational efficiency, minimize food waste •Growth in airline passenger travel underscores need for sustainable excellence in aerospace industry-related commercial services •Digital twin experience with the 3DEXPERIENCE platform bridges the gap between the virtual and real for in-flight catering production

Canada's Atlantic Ocean-bordering provinces are making the most of their coastal resources, using decades of knowhow to balance economic growth with sustainability.

At the reveal of Tesla's redesigned Roadster in 2017, the company said the car would start production in 2020. At the time we said the company was notorious for being late on deadlines, and we were right to say it. In a podcast interview with comedian Joe Rogan on Thursday, Tesla CEO Elon Musk said the redesigned Roadster would be pushed back to...

The first power has been produced at the MeyGen tidal power site in Scotland, according to project developer Atlantis Resources Ltd.

The renewable energy industry has come a long way in relatively little time. The costs of renewable technologies continue to go down, while renewable capacities at many utilities continue to go up. Although, in many cases, renewable technology is mature and ready for utility-scale deployment, state and federal production and investment tax policies appear less evolved.

With its revival for fiscal year 2014, the Hydroelectric Production Incentives Program shows promise as a new federal revenue stream for hydro facilities.

By Boy Lüthje HONOLULU (6 April 2020)—The development of electric and self-driving vehicles is bringing on a massive restructuring of the global automotive industry. Emerging forms of new and shared mobility undermine the very model of private car ownership that has underpinned the automotive industry since the days of Henry Ford.

This is a summary only. Click the title for the full article, or visit www.EastWestCenter.org/Research-Wire for more.

LG International Corp., Korea's leading general trading company, is set to kick off the operation of a cement factory in Myanmar for which it has invested for two years. This is part of the company's strategy to preempt the rapidly growing Myanmar market by becoming the first general trading firm to build a cement plant in the Southeast Asian nation. According to industry sources on September 11, LG International is currently making a pilot run of the cement plant in the erstwhile reclusive c...

JEFFERSON CITY, Mo. (AP) " Frustrated by scarce supplies and a chaotic...

By DAVID A. LIEB JEFFERSON CITY, Mo. (AP) — Frustrated by scarce supplies and a chaotic marketplace amid the coronavirus outbreak, some U.S. governors are seeking to bolster their home-state production of vital medical and protective equipment to ensure a reliable long-term source for state stockpiles. The efforts come as states have been competing against each other, the federal government, hospitals, emergency responders and even other countries to get items such as N95 masks, gloves, medical gowns and hand sanitizer — often paying higher-than-usual prices because of the high demand. Before the coronavirus pandemic, the U.S. got much of its medical supplies from China. But China limited...

JEFFERSON CITY, Mo. (AP) — Frustrated by scarce supplies and a chaotic marketplace amid the coronavirus outbreak, some U.S. governors are seeking to bolster their home-state production of vital medical and protective equipment to ensure a reliable long-term source for state stockpiles. The efforts come as states have been competing against each other, the federal government, hospitals, emergency responders and even other countries to get items such as N95 masks, gloves, medical gowns and hand sanitizer — often paying higher-than-usual prices because of the high demand. Before the coronavirus pandemic, the U.S. got much of its medical supplies from China. But China limited exports earlier...

Many anime releases have been delayed indefinitely due to the COVID-19 outbreak, but in the meantime, with their vast libraries of anime films and series, ...

A senior civil servant overseeing the distribution of reusable masks to all Hongkongers has promised to put the production of their replacement filters out to tender after admitting to shortcomings in the transparency of the original contract awarded by the government.Annie Choi Suk-han, permanent secretary of the Innovation and Technology Bureau, on Friday rejected suggestions the government had intentionally hidden the identity of the manufacturer chosen for the HK$320 million (US$41 million)…

The transmission channels of perishables like fruits and vegetables from producers to consumers in developing countries need a revamp to provide benefits to all involved.

ADB and the Government of Mongolia today signed $40 million in loans and a $2 million Japan Fund for Poverty Reduction grant to support the modernization of government-owned irrigation networks and vegetable production in Mongolia.

Approved project 51423-002 in Mongolia.

Stamford, Connecticut – February 03, 2020 – HARMAN International, a wholly-owned subsidiary of Samsung Electronics Co., Ltd. focused on connected technologies for automotive, consumer and enterprise markets, has launched the world’s first active road...

Auto production in Mexico and Brazil, Latin America's top producers, plunged by an unprecedented 99% in April as a result of the coronavirus crisis, with the two countries building a total of just 5,569 vehicles.

Pfizer Inc said on Friday it is in talks to shift more of its medicine production to outside contractors as it prepares for large-scale production of an experimental vaccine to prevent COVID-19, should it prove safe and effective.

Pfizer Inc said on Friday it is in talks to shift more of its medicine production to outside contractors as it prepares for large-scale production of an experimental vaccine to prevent COVID-19, should it prove safe and effective.

The BCG tuberculosis vaccine boosts the production of immune cells and this may explain how it protects newborns from dying of sepsis

Title: Production of Two Excedrin Painkillers Halted
Category: Health News
Created: 1/22/2020 12:00:00 AM
Last Editorial Review: 1/22/2020 12:00:00 AM

Hydrogen sulfide (H₂S), a plant gasotransmitter, functions in the plant response to cadmium (Cd) stress, implying a role for cysteine desulfhydrase in producing H₂S in this process. Whether d-CYSTEINE DESULFHYDRASE (DCD) acts in the plant Cd response remains to be identified, and if it does, how DCD is regulated in this process is also unknown. Here, we report that DCD-mediated H₂S production enhances plant Cd tolerance in Arabidopsis (Arabidopsis thaliana). When subjected to Cd stress, a dcd mutant accumulated more Cd and reactive oxygen species and showed increased Cd sensitivity, whereas transgenic lines overexpressing DCD had decreased Cd and reactive oxygen species levels and were more tolerant to Cd stress compared with wild-type plants. Furthermore, the expression of DCD was stimulated by Cd stress, and this up-regulation was mediated by a Cd-induced transcription factor, WRKY13, which bound to the DCD promoter. Consistently, the higher Cd sensitivity of the wrky13-3 mutant was rescued by the overexpression of DCD. Together, our results demonstrate that Cd-induced WRKY13 activates DCD expression to increase the production of H₂S, leading to higher Cd tolerance in plants.

Terpene volatiles are found in many important fruit crops, but their relationship to flavor is poorly understood. Here, we demonstrate using sensory descriptive and discriminant analysis that 1,8-cineole contributes a key floral/eucalyptus note to the aroma of ripe 'Hort16A’ kiwifruit (Actinidia chinensis). Two quantitative trait loci (QTLs) for 1,8-cineole production were identified on linkage groups 27 and 29a in a segregating A. chinensis population, with the QTL on LG29a colocating with a complex cluster of putative terpene synthase (TPS)-encoding genes. Transient expression in Nicotiana benthamiana and analysis of recombinant proteins expressed in Escherichia coli showed four genes in the cluster (AcTPS1a–AcTPS1d) encoded functional TPS enzymes, which produced predominantly sabinene, 1,8-cineole, geraniol, and springene, respectively. The terpene profile produced by AcTPS1b closely resembled the terpenes detected in red-fleshed A. chinensis. AcTPS1b expression correlated with 1,8-cineole content in developing/ripening fruit and also showed a positive correlation with 1,8-cineole content in the mapping population, indicating the basis for segregation is an expression QTL. Transient overexpression of AcTPS1b in Actinidia eriantha fruit confirmed this gene produced 1,8-cineole in Actinidia. Structure-function analysis showed AcTPS1a and AcTPS1b are natural variants at key TPS catalytic site residues previously shown to change enzyme specificity in vitro. Together, our results indicate that AcTPS1b is a key gene for production of the signature flavor terpene 1,8-cineole in ripe kiwifruit. Using a sensory-directed strategy for compound identification provides a rational approach for applying marker-aided selection to improving flavor in kiwifruit as well as other fruits.

Jessica M. Judson, Dawn M. Reding, and Anne M. Bronikowski

Immunosenescence is a well-known phenomenon in mammal systems, but its relevance in other long-lived vertebrates is less understood. Further, the influence of age and reproductive effort on immune function in long-lived species can be challenging to assess, as long-term data are scarce and it is often difficult to sample the oldest age classes. We used the painted turtle (Chrysemys picta) to test hypotheses of immunosenescence and a trade-off between reproductive output and immune function in a population of a long-lived vertebrate that has been monitored for over 30 years. These long-term data are utilized to employ a unique approach of aging turtles with mark-recapture data and population-specific growth modeling to obtain more accurate estimates of age. We analyzed natural antibodies, lysis ability, and bactericidal competence in 126 individuals from 1 to 33 years of age captured during May and June in 2011. Older turtles exhibited greater natural antibody levels than young individuals across sexes. Young females with large clutches exhibited greater lysis ability, while older females with large clutches had decreased lysis ability, suggesting a trade-off between reproductive output and immune function conditional upon age. However, bactericidal competence increased later in the nesting season for older females. Our study rejects the hypothesis of immunosenescence in a long-lived turtle, despite evidence of actuarial and reproductive senescence in this population. Additionally, we detected mixed evidence for a trade-off between reproduction and immune health.

Understanding fructose metabolism might provide insights to renal pathophysiology. To support systemic glucose concentration, the proximal tubular cells reabsorb fructose as a substrate for gluconeogenesis. However, in instances when fructose intake is excessive, fructose metabolism is costly, resulting in energy depletion, uric acid generation, inflammation, and fibrosis in the kidney. A recent scientific advance is the discovery that fructose can be endogenously produced from glucose under pathologic conditions, not only in kidney diseases, but also in diabetes, in cardiac hypertrophy, and with dehydration. Why humans have such a deleterious mechanism to produce fructose is unknown, but it may relate to an evolutionary benefit in the past. In this article, we aim to illuminate the roles of fructose as it relates to gluconeogenesis and fructoneogenesis in the kidney.

Taurine is one of the most abundant amino acids in mammalian tissues. It is obtained from the diet and by de novo synthesis from cysteic acid or hypotaurine. Despite the discovery in 1954 that the oxygenation of hypotaurine produces taurine, the identification of an enzyme catalyzing this reaction has remained elusive. In large part, this is due to the incorrect assignment, in 1962, of the enzyme as an NAD-dependent hypotaurine dehydrogenase. For more than 55 years, the literature has continued to refer to this enzyme as such. Here we show, both in vivo and in vitro, that the enzyme that oxygenates hypotaurine to produce taurine is flavin-containing monooxygenase (FMO) 1. Metabolite analysis of the urine of Fmo1-null mice by ¹H NMR spectroscopy revealed a buildup of hypotaurine and a deficit of taurine in comparison with the concentrations of these compounds in the urine of wild-type mice. In vitro assays confirmed that human FMO1 catalyzes the conversion of hypotaurine to taurine, utilizing either NADPH or NADH as cofactor. FMO1 has a wide substrate range and is best known as a xenobiotic- or drug-metabolizing enzyme. The identification that the endogenous molecule hypotaurine is a substrate for the FMO1-catalyzed production of taurine resolves a long-standing mystery. This finding should help establish the role FMO1 plays in a range of biologic processes in which taurine or its deficiency is implicated, including conjugation of bile acids, neurotransmitter, antioxidant and anti-inflammatory functions, and the pathogenesis of obesity and skeletal muscle disorders.

OBJECTIVE

Sodium–glucose cotransporter 2 (SGLT2) inhibition causes an increase in endogenous glucose production (EGP). However, the mechanisms are unclear. We studied the effect of SGLT2 inhibitors on EGP in subjects with type 2 diabetes (T2D) and without diabetes (non-DM) in kidney transplant recipients with renal denervation.

Microsoft and Sony are both hard at working preparing their next generation consoles, the Xbox Series X and PlayStation 5, for launch this holiday season. 

A key factor in getting as many consoles shipped for both companies will be from AMD, who will be providing the latest Zen 2-powered CPU and matching Navi GPU.

AMD is ramping up production as they expect semi-custom revenue to grow in the second quarter and have a big increase in the second half of 2020 as they provide parts for the Xbox Series X and PS5. 

"We expect semi-custom revenue to increase in the second quarter and be heavily weighted towards the second-half of the year, as we ramp production to support the holiday launches of the new PlayStation 5 and Xbox Series X consoles," said AMD CEO Dr. Lisa Su. 

Thanks Tom's Hardware.

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel dedicated to gaming Let's Plays and tutorials. You can contact the author at wdangelo@vgchartz.com or on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/443398/amd-ramping-up-cpu-production-for-xbox-series-x-and-playstation-5/

COMPUTER services company PTC is using augmented reality , the enhanced visual technology seen in Pokemon Go smartphone games and Iron Man movies, to produce ventilators in record time for the NHS.

The BCG tuberculosis vaccine boosts the production of immune cells and this may explain how it protects newborns from dying of sepsis

Alongside its financial results for Q1

After two months of strict lockdown due of coronavirus pandemic,...

The post Prada Restarts Production In Italy appeared first on Man's World India.

Meat production this week is up about 3 percent compared with the previous week, according to market reports by SiriusXM’s Rural Radio. That’s still off by as much as a third from a year ago. The numbers are causing some retailers to ration fresh meat purchases or risk selling out their entire supplies. The beef,... Continue Reading

Hydrogen is a possible next generation energy solution, and it can be produced from sunlight and water using photocatalysts. A research group has now developed a strategy that greatly increases the amount of hydrogen produced using hematite photocatalysts. In addition to boosting the high efficiency of what is thought to be the world's highest performing photoanode, this strategy will be applied to artificial photosynthesis and solar water-splitting technologies via university-industry collaborations.

Tesla Inc has not been allowed to resume operations at its California vehicle factory as local lockdown measures to curb the spread of the coronavirus remain in effect, a county health official said on Friday.

Pfizer Inc said on Friday it is in talks to shift more of its medicine production to outside contractors as it prepares for large-scale production of an experimental vaccine to prevent COVID-19, should it prove safe and effective.

Follow our live coronavirus updates here Coronavirus: the symptoms

Frustrated by scarce supplies and a chaotic marketplace amid the coronavirus outbreak, some U.S. governors are seeking to bolster their home-state production of vital medical and protective equipment to ensure a reliable long-term source for state stockpiles. The efforts come as states have been competing against each other, the federal government, hospitals, emergency responders and even other countries to get items such as N95 masks, gloves, medical gowns and hand sanitizer — often paying higher-than-usual prices because of the high demand. Before the coronavirus pandemic, the U.S. got much of its medical supplies from China.

No major Hollywood film since has attempted anything quite like Cast Away.

'Weekend Update' among segments returning

The production company behind the megahit Deadpool 2 has been fined nearly $290,000 for violating multiple safety rules leading to the death of a stuntwoman on a set in Vancouver in 2017.

Australia's largest flour mill will produce an extra 50 million kilograms by the middle of the year as consumer demand goes through the roof.

General Motors says it plans to restart some production at its engine plant in St. Catharines, Ont. next week ahead of a wider restart of North American operations the week of May 18.

AdvaMed has announced the launch of a new platform, which will attempt to connect ventilator companies with component suppliers to ensure quick scale production and distribution of these devices during the Covid-19 pandemic.